id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-277603-hpn1ovgo	Strapazzon, Giacomo	To compare the incomparable: COVID-19 pneumonia and high-altitude disease	2020-06-25		.txt	text/plain	1055	60	39	Some clinicians have found the clinical features of COVID-19 pneumonia to be similar to high-altitude pulmonary oedema (HAPE) [1] , and such theory has been amplified via social media. The assumption that the clinical features of COVID-19 pneumonia are similar to HAPE [1] may rely on the initial clinical presentation of COVID-19 patients, showing profound hypoxaemia with no respiratory distress, similar to patients with acute high-altitude disease that have a chemoreceptor dysfunction. The pathogenesis of the two diseases (HAPE and COVID-19 pneumonia) is clearly different, despite similarities in clinical features, chest imaging and bronchoalveolar lavage findings in later stages, as has recently been emphasised by LUKS et al. The use @ERSpublications COVID-19 pneumonia is a viral infection; high-altitude pulmonary oedema is a non-cardiogenic oedema. Clinicians should focus on the development of therapeutic strategies based on the pathogenesis of the disease, and should remember that COVID-19 pneumonia is a viral infection primarily leading to diffuse alveolar damage and airway inflammation.	./cache/cord-277603-hpn1ovgo.txt	./txt/cord-277603-hpn1ovgo.txt