id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-304550-6j1pb1pu	Yongchen, Zhang	Different longitudinal patterns of nucleic acid and serology testing results based on disease severity of COVID-19 patients	2020-05-02		.txt	text/plain	2032	108	43	Here, we conducted a serial investigation on 21 individuals infected with SARS-CoV-2 in two medical centres from Jiangsu Province, including 11 non-severe COVID-19 patients, and 5 severe COVID-19 patients and 5 asymptomatic carriers based on nucleic acid test and clinical symptoms. In this respective study, we serially analysed the virus RNA test results in swab samples, along with anti-SARS-CoV-2 IgM and IgG responses among 21 COVID-19 patients at the Second Hospital of Nanjing and the Affiliated Hospital of Xuzhou Medical University in Jiangsu Province, China. Our serial SARS-CoV-2 RNA testing identified a prolonged viral shedding for asymptomatic cases compared to COVID-19 patients, suggesting the importance of early identification and timely quarantine for these asymptomatic carriers. It is possible that significantly high level of SARS-CoV-2 viral load observed in severe cases [8, 9] drives an early antibody response produced by immediate activation of extrafollicular B cells during acute infection [10, 11] .	./cache/cord-304550-6j1pb1pu.txt	./txt/cord-304550-6j1pb1pu.txt