id author title date pages extension mime words sentences flesch summary cache txt cord-291877-7sgxiilt Cruz Salcedo, Elis M Use of Dexmedetomidine in Early Prone Positioning Combined With High-Flow Nasal Cannula and Non-Invasive Positive Pressure Ventilation in a COVID-19 Positive Patient 2020-09-13 .txt text/plain 1717 76 37 Patients who are developing ARDS secondary to COVID-19 pneumonia have been treated with self-proning intervals in combination with supplementation of oxygenation via high-flow nasal cannula (HFNC) or non-invasive positive pressure ventilation (NIPPV); however, a few patients have poor tolerance to the devices, leading to poor compliance and eventual worsening respiratory symptoms leading to intubation. In the current case report, we detail how a patient was able to successfully be self-proned with proper tolerance to HFNC and NIPPV while using dexmedetomidine, leading to discharge without the need for further oxygen supplementation at home. Our case details a patient with COVID-19 pneumonia who was successfully managed with awake self-proning while using dexmedetomidine in combination with HFNC and noninvasive positive pressure ventilation (NIPPV) during the beginning stages of the disease in order to promote increased adherence to proning cycles and oxygen support equipment, to prevent endotracheal intubation. ./cache/cord-291877-7sgxiilt.txt ./txt/cord-291877-7sgxiilt.txt