id author title date pages extension mime words sentences flesch summary cache txt cord-273741-ipnt6g0i Khan, Adeel A Fluid Replacement Versus Fluid Restriction in COVID-19 Associated Hyponatremia 2020-07-08 .txt text/plain 1186 91 45 Literature describes syndrome of inappropriate anti diuretic hormone (SIADH) as the mechanism of hyponatremia in COVID-19 requiring fluid restriction for management. We present a case of hypovolemic hyponatremia in a patient with COVID-19, which unlike SIADH, required fluid replacement early in the disease course for its correction. Hypovolemic hyponatremia should be distinguished from SIADH as these conditions employ different management strategies, and early diagnosis and management of hypovolemic hyponatremia affects morbidity and mortality. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been recently reported to manifest as hyponatremia secondary to syndrome of inappropriate anti diuretic hormone (SIADH ) [2] [3] [4] [5] [6] . With the prevalence of gastrointestinal (GI) symptoms in coronavirus disease 2019 (COVID-19), there is a possibility of hypovolemic hyponatremia secondary to GI loss [7] . An early clinical judgement should consider the volume status of the COVID-19 patients with hyponatremia to decide between fluid restriction and isotonic fluid replacement. ./cache/cord-273741-ipnt6g0i.txt ./txt/cord-273741-ipnt6g0i.txt