id author title date pages extension mime words sentences flesch summary cache txt cord-262886-irmwqjfh Beiu, Cristina Frequent Hand Washing for COVID-19 Prevention Can Cause Hand Dermatitis: Management Tips 2020-04-02 .txt text/plain 1626 91 47 Frequent hand washing implies a prolonged exposure to water and other chemical or physical agents and may induce several pathophysiologic changes, such as epidermal barrier disruption, impairment of keratinocytes, the subsequent release of proinflammatory cytokines, activation of the skin immune system, and delayed-type hypersensitivity reactions. This article aims to review the potential dermatological adverse effects that may arise due to frequent hand washing, as well as practical tips for preventing these uncomfortable skin reactions. Frequent hygienization of hands may generate various changes in skin texture, ranging from the development of cutaneous xerosis (dryness of the skin) up to irritant contact dermatitis (ICD) or, rarely, even allergic contact dermatitis (ACD). In these times, it is very important to adapt our hand washing habits to ensure efficient protection against the spread of COVID-19 while lowering the risk of skin adverse reactions. Regular skin hydration is a key component in preventing hand dermatitis as a consequence of frequent washing. ./cache/cord-262886-irmwqjfh.txt ./txt/cord-262886-irmwqjfh.txt