id author title date pages extension mime words sentences flesch summary cache txt cord-287490-g1r9zew2 Despres, Cyrielle Prone positioning combined with high-flow nasal or conventional oxygen therapy in severe Covid-19 patients 2020-05-26 .txt text/plain 874 65 55 title: Prone positioning combined with high-flow nasal or conventional oxygen therapy in severe Covid-19 patients Prone positioning combined with high-flow nasal or conventional oxygen therapy in severe Covid-19 patients Cyrielle Despres 1 , Yannick Brunin 1 , Francis Berthier 1 , Sebastien Pili-Floury 1,2 and Guillaume Besch 1,2* Dear Editor, A massive outbreak of coronavirus disease 2019 (Covid-19) occurred in France in March and April 2020. We report the case of 6 severe Covid-19 patients admitted to our critical care unit between March and April 2020, who had PP combined with either highflow nasal oxygen (HFNO) or conventional oxygen therapy (COT). The efficacy of PP combined with HFNO therapy or non-invasive ventilation was recently reported in small cohorts of non-infectious and infectious non-Covid-19 ARDS patients [2, 3] . Considering these observations, PP combined with either HFNO or COT could be proposed in spontaneously breathing, severe Covid-19 patients to avoid intubation. Prone positioning combined with high-flow nasal cannula in severe noninfectious ARDS ./cache/cord-287490-g1r9zew2.txt ./txt/cord-287490-g1r9zew2.txt