id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-255216-87ursh0s	de Castro, Isabel Fernández	First evidence of a pro-inflammatory response to severe infection with influenza virus H1N1	2010-02-11		.txt	text/plain	1313	82	53	This is the first work reporting the association of a pro-inflamatory immune response with a severe pandemic infection, although it is likely that more studies are needed to understand the detrimental or beneficial roles these cytokines play in the evolution of mild and severe nvH1N1 infection. By analyzing 29 cytokines and chemokines and the hemagglutination inhibition activity, Bermejo-Martin and colleagues [1] assessed the early host innate and adaptive immune responses in patients both mildly and severely infected with nvH1N1. The great majority of infections caused by the pandemic variant of the infl uenza virus (nvH1N1) are self-limited, but a small percentage of patients develop severe symptoms requiring hospitalization. This is the fi rst work reporting the association of a pro-infl amatory immune response with a severe pandemic infection, although it is likely that more studies are needed to understand the detrimental or benefi cial roles these cytokines play in the evolution of mild and severe nvH1N1 infection.	./cache/cord-255216-87ursh0s.txt	./txt/cord-255216-87ursh0s.txt