id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-325186-nq6ay4eo	Sieswerda, Elske	Recommendations for antibacterial therapy in adults with COVID-19 – An evidence based guideline	2020-10-01		.txt	text/plain	855	65	37	SCOPE: The Dutch Working Party on Antibiotic Policy constituted a multidisciplinary expert committee to provide evidence-based recommendation for the use of antibacterial therapy in hospitalized adults with a respiratory infection and suspected or proven 2019 Coronavirus disease (COVID-19). QUESTIONS ADDRESSED BY THE GUIDELINE AND RECOMMENDATIONS: We assessed evidence on the risk of bacterial infections in hospitalized COVID-19 patients, the associated bacterial pathogens, how to diagnose bacterial infections and how to treat bacterial infections. For patients with secondary bacterial respiratory infection we recommend to follow other guideline recommendations on antibacterial treatment for patients with hospital-acquired and ventilator-associated pneumonia. An antibiotic treatment duration of five days in patients with COVID-19 and suspected bacterial respiratory infection is recommended upon improvement of signs, symptoms and inflammatory markers. As COVID-19 patients frequently 72 need prolonged hospitalization and respiratory support, unnecessary antibiotics upon 73 hospitalization may increase the individual risk of subsequent hospital-acquired pneumonia 74 (HAP) and other adverse events [12, 13] .	./cache/cord-325186-nq6ay4eo.txt	./txt/cord-325186-nq6ay4eo.txt