id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-015493-vf4et613	Deresinski, Stan	In the Literature	2007-10-15		.txt	text/plain	1565	67	45	Tetracyclines as an oral treatment option for patients with community-onset methicillin-resistant Staphylococcus aureus skin and soft-tissue infections. Subgroup analysis that included only the 225 episodes in which incision and drainage were performed at presentation confirmed that blactam antibiotic therapy was significantly associated with treatment failure. These results are consistent with those of several other recent studies that have found that administration of an antibiotic that inhibits the growth of MRSA improves outcomes, even in patients who have undergone incision and drainage. For example, in a similar retrospective study of 531 episodes of community-acquired MRSA SSTI, most of which were treated with incision and drainage, Ruhe et al. Although Ruhe and colleagues provide evidence of the benefit of doxycyline for the treatment of SSTI due to antibioticsusceptible MRSA, alternative antibiotic choices may be considered. Prospective randomized trial of empiric therapy with trimethoprim-sulfamethoxazole or doxycycline for outpatient skin and soft tissue infections in an area of high prevalence of methicillin-resistant Staphylococcus aureus	./cache/cord-015493-vf4et613.txt	./txt/cord-015493-vf4et613.txt