id author title date pages extension mime words sentences flesch summary cache txt cord-287386-x8uq7499 Kongsted, Hanne Microbiological, pathological and histological findings in four Danish pig herds affected by a new neonatal diarrhoea syndrome 2013-10-12 .txt text/plain 4484 248 49 CONCLUSIONS: The results of the study supported the hypothesis that a new neonatal porcine diarrhoea was present in the investigated herds, since no known pathogen(s) or management factors could explain the diarrhoeal outbreaks. Based on the findings in the four herds the following case-definition of NNPDS was suggested: Non-haemorrhagic diarrhoea during the first week of life, without detection of known infectious pathogens, characterized by milk-filled stomachs and flaccid intestines at necropsy. The article describes the prevalence of well-known enteric pathogens in age-matched diarrhoeic-and nondiarrhoeic piglets from four herds affected by neonatal diarrhoea with no previously established laboratory conclusion. Herds were recommended by veterinary practitioners and included in accordance with the following criteria: 1) Presence of diarrhoea responding poorly to antibiotics during the first week of life (at least 30% affected litters for a period of minimum 6 months), 2) Routine vaccination of sows against ETEC and CPC, 3) Failure of preventive management interventions, 4) PRRS negative farrowing unit as demonstrated in blood samples tested by ELISA/IPT or PCR and 5) Negative results of routine diagnostic examinations for ETEC, CPC and RV in five diarrhoeic piglets aged one to four days. ./cache/cord-287386-x8uq7499.txt ./txt/cord-287386-x8uq7499.txt