id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-304718-w469n0o8	Wang, Yan	Lack of association between polymorphisms of MASP2 and susceptibility to SARS coronavirus infection	2009-05-01		.txt	text/plain	2595	161	51	One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As the downstream protein of MBL, variants of the MBL-associated serine protease-2 (MASP2) gene may be associated with SARS coronavirus (SARS-CoV) infection in the same population. RESULTS: There is no significant association between alleles or genotypes of the MASP2 tagSNP and susceptibility to SARS-CoV in both Beijing and Guangzhou populations. A few case-control studies have reported an association between SARS susceptibility and human leucocyte antigen (HLA) and MBL [8] [9] [10] [11] . With regard to SARS-CoV infection, the codon 54 variant of the MBL gene has been shown to be associated with infection susceptibility but not with disease severity [11] . As the downstream protein of MBL, variants of the MASP2 gene may be associated with SARS-CoV infection. Genomic DNA from 30 individuals with SARS was chosen for analysis of MASP2 gene polymorphisms.	./cache/cord-304718-w469n0o8.txt	./txt/cord-304718-w469n0o8.txt