id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-297494-6yxmaihl	Katsurada, Naoko	The impact of virus infections on pneumonia mortality is complex in adults: a prospective multicentre observational study	2017-12-06		.txt	text/plain	4336	217	38	However, influenza virus A and B were associated with three-fold higher mortality in patients with chronic respiratory disease but not with other comorbidities (ARR 3.38, 95% CI 1.54–7.42). We conducted this prospective multicentre study to determine the distribution of viruses associated with pneumonia in adults and to establish their virus-specific effects on pneumonia mortality stratified by age group and comorbidity status. To the best of our knowledge, this study is the first to systematically investigate virus-specific effects on pneumonia mortality by age group and comorbidity status among adults. In our study, multiple viruses were identified in 5.1% of virus-associated pneumonia and were associated with higher mortality than single viral infection in patients with chronic respiratory disease and other comorbidities. Systematic reviews have shown that multiple viral infections in patients with respiratory disease are not associated with disease severity [27, 28] ; however, the majority of previous studies included young children but not adults.	./cache/cord-297494-6yxmaihl.txt	./txt/cord-297494-6yxmaihl.txt