id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-000534-ztc5holk	Hsieh, Ying-Hen	Transmissibility and temporal changes of 2009 pH1N1 pandemic during summer and fall/winter waves	2011-12-02		.txt	text/plain	5201	205	53	BACKGROUND: In order to compare the transmissibility of the 2009 pH1N1 pandemic during successive waves of infections in summer and fall/winter in the Northern Hemisphere, and to assess the temporal changes during the course of the outbreak in relation to the intervention measures implemented, we analyze the epidemiological patterns of the epidemic in Taiwan during July 2009-March 2010. METHODS: We utilize the multi-phase Richards model to fit the weekly cumulative pH1N1 epidemiological data (numbers of confirmed cases and hospitalizations) as well as the daily number of classes suspended under a unique "325" partial school closing policy in Taiwan, in order to pinpoint the turning points of the summer and fall/winter waves, and to estimate the reproduction numbers R for each wave. The estimates for effective reproduction number R obtained from the confirmed case and hospitalization data are in good agreement, with R in the range of 1.04-1.27 for the first summer wave during July-September, and 1.01-1.05 for the second wave in fall/winter, using the generation time estimated by [26] for the spring outbreak in Mexico.	./cache/cord-000534-ztc5holk.txt	./txt/cord-000534-ztc5holk.txt