id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-303978-z3888e3g	Hong, Ka Lok	Single-Stranded DNA Aptamers against Pathogens and Toxins: Identification and Biosensing Applications	2015-06-23		.txt	text/plain	15716	988	47	Multiple virulent strains of the gram-negative bacteria, Escherichia coli, have been chosen as targets for the selection of specific ssDNA MREs due to their enterotoxigenic effects and the potential of contaminating food and water [39] . They also developed a sandwich detection system, in which biotinylated antibodies targeting the K88 strain were immobilized on magnetic beads as the capturing element and the 5 FITC labeled ssDNA library from round 13 selection served as the reporter in a fluorescent assay. In their later study, the affinities of selected candidate MREs were improved with reported values of in the nanomolar range and were specific for the target bacteria at different growth phases [57] . Acetamiprid Immobilization free 4.98 M -[27] Fluorescence plate based cross-binding assay showed the ssDNA MRE was approximately two to five times more selective on the alpha toxin than negative targets.	./cache/cord-303978-z3888e3g.txt	./txt/cord-303978-z3888e3g.txt