id author title date pages extension mime words sentences flesch summary cache txt cord-299552-rgrm8dil Bianchi, Martina Sars-CoV-2 Envelope and Membrane Proteins: Structural Differences Linked to Virus Characteristics? 2020-05-30 .txt text/plain 2082 134 52 In this report, a structural comparison between the Sars-CoV-2 Envelope and Membrane proteins from different human isolates with homologous proteins from closely related viruses is described. However, the comparisons have also highlighted structural differences specific of Sars-CoV-2 proteins which may be correlated to the cross-species transmission and/or to the properties of the virus. In this report, a structural comparison between the Sars-CoV-2 surface proteins from different isolates with homologous proteins from closely related viruses such as those from Bat and Pangolin is described. Sars-CoV-2 E sequences differ from the homologous proteins also at positions 55-56, where the dyad Ser-Phe replaces Thr-Val (except in Bat coronavirus isolate BtKY72, accession code KY352407). In this paper, E and M proteins from 797 Sars-CoV-2 genomes have been compared to the counterparts taken from the most closely related virus also to evaluate the potential role of amino acid mutations in the epizootic origin of COVID-19. ./cache/cord-299552-rgrm8dil.txt ./txt/cord-299552-rgrm8dil.txt