id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-012089-haqqrwad	Baez, Antonino	High-flux isobutanol production using engineered Escherichia coli: a bioreactor study with in situ product removal	2011-03-10		.txt	text/plain	4345	248	57	Since the feasibility of a bioprocess depends critically on the final product titer (Stephanopoulos 2007) , a synthetic approach to produce higher alcohols from nonfermentative pathways in Escherichia coli was previously devised (Atsumi et al. 2008) , in the present work, gas stripping integrated with fermentation was used to compare the isobutanol production by the high producer (JCL260), isobutanol-tolerant (SA481), and the parental (JCL16) strains carrying pSA65 and pSA69 plasmids. Error bars represent the difference between duplicate cultures Fig. 4 Time profile of acetate production by JCL260 PoxB − mutant and high isobutanol producer (JCL260) strains harboring pSA65/pSA69 plasmids cultivated in shake flasks containing 25 mL of medium. (2010b) found that isobutanol production, cell growth, and glucose consumption rate of SA481 tested in flask cultures were similar to those of JCL260 and that improved tolerance of SA481 did not increase the final titer.	./cache/cord-012089-haqqrwad.txt	./txt/cord-012089-haqqrwad.txt