id author title date pages extension mime words sentences flesch summary cache txt cord-328468-bwn4bmf5 Mohan, Ketha V.K. Antiviral activity of selected antimicrobial peptides against vaccinia virus() 2010-03-27 .txt text/plain 4356 201 52 We have recently demonstrated the antibacterial activity of two types of AMPs, the thrombin-induced human platelet-derived antimicrobial peptides (PD) and the arginine-tryptophan (RW) repeat peptides, against aerobic bacterial contaminants encountered in blood products (Mohan et al., 2009a) . PD3, PD4 and RW3 peptides were each incubated with the virus inoculum for 2 h at room temperature and tested for antiviral activity by performing the plaque assay as described in the pre-infection experiment. Analysis of the post virus-binding experiment revealed that none of the PD or RW peptides were able to inhibit virus infection as there was no significant difference in the viral titers between the test and control groups (Fig. 2) . Human plasma samples spiked with 10 2 pfu of VV-WR virus were incubated with PD3, PD4 and RW3 peptides individually for 2 h and tested for antiviral activity by infecting B-SC-1 cells and measuring virus titer by performing the plaque assay as described in the pre-infection experiment. ./cache/cord-328468-bwn4bmf5.txt ./txt/cord-328468-bwn4bmf5.txt