id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-286831-ni7qfjk9	Choi, Hwa-Jung	Antiviral activity of quercetin 7-rhamnoside against porcine epidemic diarrhea virus	2008-11-06		.txt	text/plain	3826	208	57	Following this, 0.09 mL of diluted virus suspension of PEDV containing CCID 50 (50% cell culture infective dose) of the virus stock to produce a appropriate cytopathic effects within 2 days after infection and 0.01 mL of medium supplemented with typsin-EDTA containing an appropriate concentration of the compounds were added. Current antiviral drugs, natural compounds and flavonoids were further studied for their inhibitory effects on replication of the PEDV and cytotoxicity in Vero cells, among which ribavirin, tannic acid, coumarin and interferon-␣ exhibited the activities with IC 50 of 4.1, 47.4, 9 g/mL and 0.52 unit, respectively. A similar result was obtained in control infections with treated ribavirin (Fig. 1 ), but antiviral activity was shown to be lower than that of Q7R. Trials of ribavirin in this study showed that the drug had favorable effects on antiviral activity in Vero cells infected with PEDV.	./cache/cord-286831-ni7qfjk9.txt	./txt/cord-286831-ni7qfjk9.txt