id author title date pages extension mime words sentences flesch summary cache txt cord-257271-jzmwy4yi Lin, Jung-Chung Inhibitory effects of some derivatives of glycyrrhizic acid against Epstein-Barr virus infection: Structure–activity relationships 2008-03-31 .txt text/plain 4112 229 50 Previously we showed that GL inhibits Epstein-Barr virus (EBV) infection in vitro by interfering with an early step of the EBV replication cycle (possibly attachment/penetration). In previous years, we have shown that many nucleoside analogs selectively inhibit replication of Epstein-Barr virus (EBV) in vitro (Lin et al., 1983 (Lin et al., , 1984 (Lin et al., , 1985 (Lin et al., , 1987 (Lin et al., , 1991 (Lin et al., , 1992 Lin and Machida, 1988; Mar et al., 1995; for a review see Gershburg and Pagano, 2005; Lin, 2006) . As an assay system for drug effects we used Raji cells superinfected with P3HR-1 (LS) virus, which results in reactivation of the latent EBV infection and replication of virus. To determine the dose-dependent effect of GL derivatives, Raji cells were superinfected with P3HR-1 (LS) virus in the presence of various concentrations of compounds. ./cache/cord-257271-jzmwy4yi.txt ./txt/cord-257271-jzmwy4yi.txt