id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-255902-fxlbx84w	Shephard, Adrian	Virucidal action of sore throat lozenges against respiratory viruses parainfluenza type 3 and cytomegalovirus	2015-09-25		.txt	text/plain	3434	191	55	In this study, we investigated whether these lozenges also have virucidal effects in vitro against two viruses associated with respiratory tract infections, parainfluenza virus type 3 and cytomegalovirus. These findings suggest that AMC/DCBA lozenge and hexylresorcinol lozenge have the potential to have local antiviral effects in patients with sore throat due to viral respiratory tract infections. AMC/DCBA lozenges have also been shown to have some virucidal effects in vitro on three enveloped viruses -RSV, influenza A virus and severe acute respiratory syndrome coronavirus (SARS-CoV) (Oxford et al., 2005) . This study investigated the in vitro virucidal activity of AMC/ DCBA alone and in a lozenge on two other enveloped viruses that can cause sore throat and respiratory illness -PIV type 3 (PIV3) and CMV (Bisno, 2001) . Taken together, these data support the use of these lozenges as a first-line treatment for sore throat caused by viral RTIs. Further investigation into the mechanisms of action and the clinical effects of AMC/DCBA and hexylresorcinol for the control of RTIs is warranted.	./cache/cord-255902-fxlbx84w.txt	./txt/cord-255902-fxlbx84w.txt