id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-345674-wkwqlnz2	Kobayashi, Jun	Nitric oxide inhalation as an interventional rescue therapy for COVID-19-induced acute respiratory distress syndrome	2020-05-20		.txt	text/plain	857	49	41	Given the extent of the COVID-19 pandemic, and the large numbers of hospitalized patients requiring respiratory support, clinical use of inhaled nitric oxide may become an alternate rescue therapy before extracorporeal membrane oxygenation for the management of acute respiratory distress syndrome in patients with COVID-19. While there is no specific recommended antiviral treatment, and vaccines have yet to be developed, the authors provided a powerful pharmacological strategy for the treatment of critically ill patients with COVID-19 acute respiratory distress syndrome (ARDS). In this review article, the drug applications for COVID-19 are well described according to disease severity; however, nitric oxide (NO) inhalation therapy, which is not described in this review, may be included in the strategy as a promising therapeutic candidate. Protocol of a randomized controlled trial testing inhaled nitric oxide in mechanically ventilated patients with severe acute respiratory syndrome in COVID-19 (SARS-CoV-2).	./cache/cord-345674-wkwqlnz2.txt	./txt/cord-345674-wkwqlnz2.txt