id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-316681-b46ycocg	Rutsaert, Lynn	COVID-19-associated invasive pulmonary aspergillosis	2020-06-01		.txt	text/plain	1229	85	43	In our 24-bedded mixed ICU, we have encountered an unexpectedly high number of COVID-19 patients developing invasive pulmonary aspergillosis. Invasive pulmonary aspergillosis (IPA) is a well-known complication in immunocompromised patients and is encountered frequently in haematopoietic stem cell or solid organ transplant recipients [2] . Severe influenza infection is a wellknown risk factor for developing IPA in non-neutropenic patients; a syndrome termed influenza-associated aspergillosis (IAA) [4] [5] [6] . Between March 12th and April 25th 2020, 34 COVID-19 patients were admitted to our ICU, of whom 20 (59%) required invasive mechanical ventilation. In the absence of host factors, as defined by the European Organisation for Research and Treatment of Cancer (EORTC) diagnostic criteria, invasive or high-risk diagnostics (biopsy, CT scan) are required to support the diagnosis of IPA [7] . Because all patients with clinical features of possible IPA were suffering from severe respiratory failure and hemodynamic instability, we initiated antifungal therapy as soon as cultures or galactomannan assays were positive.	./cache/cord-316681-b46ycocg.txt	./txt/cord-316681-b46ycocg.txt