id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-004438-jjszkq2n	Gavelli, Francesco	Transpulmonary thermodilution detects rapid and reversible increases in lung water induced by positive end-expiratory pressure in acute respiratory distress syndrome	2020-03-02		.txt	text/plain	4696	276	53	title: Transpulmonary thermodilution detects rapid and reversible increases in lung water induced by positive end-expiratory pressure in acute respiratory distress syndrome PURPOSE: It has been suggested that, by recruiting lung regions and enlarging the distribution volume of the cold indicator, increasing the positive end-expiratory pressure (PEEP) may lead to an artefactual overestimation of extravascular lung water (EVLW) by transpulmonary thermodilution (TPTD). Many studies have investigated the changes in EVLW induced by a positive end-expiratory pressure (PEEP), which is the cornerstone of ARDS treatment (Additional file 1: Table S1 ). Thus, the goal of our study, conducted in ARDS patients, was to investigate whether the estimation of EVLW by TPTD is artefactually influenced by the lung derecruitment potentially secondary to the decrease in the PEEP level. In our study, the changes in EVLW were the same among patients with high or low derecruitment, when derecruitment was assessed by the PEEP-induced change in lung volume, the method that is today the best one for estimating recruitment/derecruitment at the bedside [36] .	./cache/cord-004438-jjszkq2n.txt	./txt/cord-004438-jjszkq2n.txt