id author title date pages extension mime words sentences flesch summary cache txt cord-331109-a8e7r80d Ibrahim, Yassmin S. Case Report: Paralytic Ileus: A Potential Extrapulmonary Manifestation of Severe COVID-19 2020-08-31 .txt text/plain 2354 160 48 We report two cases of SARS-CoV-2 infection complicated by paralytic ileus. Several authors have postulated that the angiotensin-converting enzyme 2 receptors, the host receptors for COVID-19, that are present on enterocytes in both the small and large bowel might mediate viral entry and resultant inflammation. We describe two cases of severe COVID-19 pneumonia who developed paralytic ileus during their disease course, which may represent one of the luminal manifestations of severe SARS-CoV-2 infection. 7 A review of 29 studies noted that 12% of patients with SARS-CoV-2 infection had gastrointestinal symptoms, including diarrhea, nausea, and vomiting. In conclusion, we report paralytic small and large bowel ileus as a complication of COVID-19. The added value of the present case report is the detailed histopathological evidence supporting a role for COVID-19-induced micro-thrombosis, thereby compromising microcirculatory function and resultant colonic bowel dilatation and perforation in the first patient. ./cache/cord-331109-a8e7r80d.txt ./txt/cord-331109-a8e7r80d.txt