id author title date pages extension mime words sentences flesch summary cache txt cord-312841-g948h572 Kalkeri, Raj SARS-CoV-2 Shedding from Asymptomatic Patients: Contribution of Potential Extrapulmonary Tissue Reservoirs 2020-05-13 .txt text/plain 2697 153 39 Infection of such extrapulmonary organs may serve as a reservoir for SARS-CoV-2, representing a potential source of viral shedding after the cessation of respiratory symptoms in recovered patients or in asymptomatic individuals. Considering this possibility, this perspective is focused on extrapulmonary organs affected by SARS-CoV-2 and the implications of their involvement for disease transmission, clinical management strategies, and medical countermeasure discovery and development. 17 Liver, kidney, and heart abnormalities are also observed in COVID-19 patients, 18, 19 and although SARS-CoV-2 RNA is not reported in these tissues after autopsy, the detection of viral RNA in the liver of the hamster model 20 suggests the infection of these organs in patients. The identification of non-respiratory tissue reservoirs of SARS-CoV-2 suggests that further studies are needed to address implications for COVID-19 disease progression, effects on extrapulmonary tissues harboring the virus, and development of optimal medical countermeasures and disease management strategies. ./cache/cord-312841-g948h572.txt ./txt/cord-312841-g948h572.txt