id	sid	tid	token	lemma	pos
cord-341527-03rh966o	1	1	key	key	NN
cord-341527-03rh966o	1	2	:	:	:
cord-341527-03rh966o	2	1	cord-341527	cord-341527	NNP
cord-341527-03rh966o	2	2	-	-	HYPH
cord-341527-03rh966o	2	3	03rh966o	03rh966o	JJ
cord-341527-03rh966o	2	4	authors	author	NNS
cord-341527-03rh966o	2	5	:	:	:
cord-341527-03rh966o	2	6	Stockton	Stockton	NNP
cord-341527-03rh966o	2	7	,	,	,
cord-341527-03rh966o	2	8	John	John	NNP
cord-341527-03rh966o	2	9	;	;	:
cord-341527-03rh966o	2	10	Kyle	Kyle	NNP
cord-341527-03rh966o	2	11	-	-	HYPH
cord-341527-03rh966o	2	12	Sidell	Sidell	NNP
cord-341527-03rh966o	2	13	,	,	,
cord-341527-03rh966o	2	14	Cameron	Cameron	NNP
cord-341527-03rh966o	2	15	title	title	NN
cord-341527-03rh966o	2	16	:	:	:
cord-341527-03rh966o	2	17	Dexmedetomidine	Dexmedetomidine	NNP
cord-341527-03rh966o	2	18	and	and	CC
cord-341527-03rh966o	2	19	worsening	worsen	VBG
cord-341527-03rh966o	2	20	hypoxemia	hypoxemia	NN
cord-341527-03rh966o	2	21	in	in	IN
cord-341527-03rh966o	2	22	the	the	DT
cord-341527-03rh966o	2	23	setting	setting	NN
cord-341527-03rh966o	2	24	of	of	IN
cord-341527-03rh966o	2	25	COVID-19	covid-19	NN
cord-341527-03rh966o	2	26	:	:	:
cord-341527-03rh966o	2	27	A	a	DT
cord-341527-03rh966o	2	28	case	case	NN
cord-341527-03rh966o	2	29	report	report	NN
cord-341527-03rh966o	2	30	date	date	NN
cord-341527-03rh966o	2	31	:	:	:
cord-341527-03rh966o	2	32	2020	2020	CD
cord-341527-03rh966o	2	33	-	-	HYPH
cord-341527-03rh966o	2	34	05	05	CD
cord-341527-03rh966o	2	35	-	-	HYPH
cord-341527-03rh966o	2	36	27	27	CD
cord-341527-03rh966o	2	37	journal	journal	NN
cord-341527-03rh966o	2	38	:	:	:
cord-341527-03rh966o	3	1	Am	be	VBP
cord-341527-03rh966o	3	2	J	J	NNP
cord-341527-03rh966o	3	3	Emerg	Emerg	NNP
cord-341527-03rh966o	3	4	Med	Med	NNP
cord-341527-03rh966o	3	5	DOI	DOI	NNP
cord-341527-03rh966o	3	6	:	:	:
cord-341527-03rh966o	4	1	10.1016	10.1016	CD
cord-341527-03rh966o	4	2	/	/	SYM
cord-341527-03rh966o	4	3	j.ajem.2020.05.066	j.ajem.2020.05.066	NNP
cord-341527-03rh966o	4	4	sha	sha	NNP
cord-341527-03rh966o	4	5	:	:	:
cord-341527-03rh966o	5	1	f256d57d72ea0553b161f7b6aae3a062832ba248	f256d57d72ea0553b161f7b6aae3a062832ba248	NNP
cord-341527-03rh966o	5	2	doc_id	doc_id	CD
cord-341527-03rh966o	5	3	:	:	:
cord-341527-03rh966o	5	4	341527	341527	CD
cord-341527-03rh966o	5	5	cord_uid	cord_uid	NNS
cord-341527-03rh966o	5	6	:	:	:
cord-341527-03rh966o	5	7	03rh966o	03rh966o	ADD
cord-341527-03rh966o	6	1	Emergency	emergency	NN
cord-341527-03rh966o	6	2	department	department	NN
cord-341527-03rh966o	6	3	management	management	NN
cord-341527-03rh966o	6	4	of	of	IN
cord-341527-03rh966o	6	5	hypoxemia	hypoxemia	NN
cord-341527-03rh966o	6	6	in	in	IN
cord-341527-03rh966o	6	7	the	the	DT
cord-341527-03rh966o	6	8	setting	setting	NN
cord-341527-03rh966o	6	9	of	of	IN
cord-341527-03rh966o	6	10	COVID-19	COVID-19	NNP
cord-341527-03rh966o	6	11	is	be	VBZ
cord-341527-03rh966o	6	12	riddled	riddle	VBN
cord-341527-03rh966o	6	13	with	with	IN
cord-341527-03rh966o	6	14	uncertainty	uncertainty	NN
cord-341527-03rh966o	6	15	.	.	.
cord-341527-03rh966o	7	1	The	the	DT
cord-341527-03rh966o	7	2	lack	lack	NN
cord-341527-03rh966o	7	3	of	of	IN
cord-341527-03rh966o	7	4	high	high	JJ
cord-341527-03rh966o	7	5	-	-	HYPH
cord-341527-03rh966o	7	6	quality	quality	NN
cord-341527-03rh966o	7	7	research	research	NN
cord-341527-03rh966o	7	8	has	have	VBZ
cord-341527-03rh966o	7	9	translated	translate	VBN
cord-341527-03rh966o	7	10	to	to	IN
cord-341527-03rh966o	7	11	an	an	DT
cord-341527-03rh966o	7	12	absence	absence	NN
cord-341527-03rh966o	7	13	of	of	IN
cord-341527-03rh966o	7	14	clarity	clarity	NN
cord-341527-03rh966o	7	15	at	at	IN
cord-341527-03rh966o	7	16	the	the	DT
cord-341527-03rh966o	7	17	bedside	bedside	NN
cord-341527-03rh966o	7	18	.	.	.
cord-341527-03rh966o	8	1	With	with	IN
cord-341527-03rh966o	8	2	disease	disease	NN
cord-341527-03rh966o	8	3	spread	spread	VBD
cord-341527-03rh966o	8	4	outpacing	outpace	VBG
cord-341527-03rh966o	8	5	treatment	treatment	NN
cord-341527-03rh966o	8	6	consensus	consensus	NN
cord-341527-03rh966o	8	7	,	,	,
cord-341527-03rh966o	8	8	provider	provider	NN
cord-341527-03rh966o	8	9	discretion	discretion	NN
cord-341527-03rh966o	8	10	has	have	VBZ
cord-341527-03rh966o	8	11	taken	take	VBN
cord-341527-03rh966o	8	12	on	on	RP
cord-341527-03rh966o	8	13	a	a	DT
cord-341527-03rh966o	8	14	heightened	heightened	JJ
cord-341527-03rh966o	8	15	role	role	NN
cord-341527-03rh966o	8	16	.	.	.
cord-341527-03rh966o	9	1	Here	here	RB
cord-341527-03rh966o	9	2	,	,	,
cord-341527-03rh966o	9	3	we	-PRON-	PRP
cord-341527-03rh966o	9	4	report	report	VBP
cord-341527-03rh966o	9	5	a	a	DT
cord-341527-03rh966o	9	6	case	case	NN
cord-341527-03rh966o	9	7	of	of	IN
cord-341527-03rh966o	9	8	dexmedetomidine	dexmedetomidine	JJ
cord-341527-03rh966o	9	9	use	use	NN
cord-341527-03rh966o	9	10	in	in	IN
cord-341527-03rh966o	9	11	the	the	DT
cord-341527-03rh966o	9	12	setting	setting	NN
cord-341527-03rh966o	9	13	of	of	IN
cord-341527-03rh966o	9	14	worsening	worsen	VBG
cord-341527-03rh966o	9	15	hypoxemia	hypoxemia	NN
cord-341527-03rh966o	9	16	,	,	,
cord-341527-03rh966o	9	17	whereby	whereby	WRB
cord-341527-03rh966o	9	18	oxygenation	oxygenation	NN
cord-341527-03rh966o	9	19	improved	improve	VBD
cord-341527-03rh966o	9	20	and	and	CC
cord-341527-03rh966o	9	21	intubation	intubation	NN
cord-341527-03rh966o	9	22	was	be	VBD
cord-341527-03rh966o	9	23	avoided	avoid	VBN
cord-341527-03rh966o	9	24	.	.	.
cord-341527-03rh966o	10	1	Well	well	UH
cord-341527-03rh966o	10	2	known	know	VBN
cord-341527-03rh966o	10	3	pharmacologic	pharmacologic	JJ
cord-341527-03rh966o	10	4	properties	property	NNS
cord-341527-03rh966o	10	5	of	of	IN
cord-341527-03rh966o	10	6	the	the	DT
cord-341527-03rh966o	10	7	drug	drug	NN
cord-341527-03rh966o	10	8	,	,	,
cord-341527-03rh966o	10	9	namely	namely	RB
cord-341527-03rh966o	10	10	the	the	DT
cord-341527-03rh966o	10	11	lack	lack	NN
cord-341527-03rh966o	10	12	of	of	IN
cord-341527-03rh966o	10	13	respiratory	respiratory	JJ
cord-341527-03rh966o	10	14	depression	depression	NN
cord-341527-03rh966o	10	15	and	and	CC
cord-341527-03rh966o	10	16	its	-PRON-	PRP$
cord-341527-03rh966o	10	17	anti	anti	JJ
cord-341527-03rh966o	10	18	-	-	JJ
cord-341527-03rh966o	10	19	delirium	delirium	JJ
cord-341527-03rh966o	10	20	effects	effect	NNS
cord-341527-03rh966o	10	21	,	,	,
cord-341527-03rh966o	10	22	as	as	RB
cord-341527-03rh966o	10	23	well	well	RB
cord-341527-03rh966o	10	24	as	as	IN
cord-341527-03rh966o	10	25	other	other	JJ
cord-341527-03rh966o	10	26	possible	possible	JJ
cord-341527-03rh966o	10	27	physiologic	physiologic	JJ
cord-341527-03rh966o	10	28	effects	effect	NNS
cord-341527-03rh966o	10	29	,	,	,
cord-341527-03rh966o	10	30	suggest	suggest	VBP
cord-341527-03rh966o	10	31	potential	potential	JJ
cord-341527-03rh966o	10	32	benefit	benefit	NN
cord-341527-03rh966o	10	33	for	for	IN
cord-341527-03rh966o	10	34	patients	patient	NNS
cord-341527-03rh966o	10	35	being	be	VBG
cord-341527-03rh966o	10	36	managed	manage	VBN
cord-341527-03rh966o	10	37	with	with	IN
cord-341527-03rh966o	10	38	a	a	DT
cord-341527-03rh966o	10	39	delayed	delay	VBN
cord-341527-03rh966o	10	40	intubation	intubation	NN
cord-341527-03rh966o	10	41	approach	approach	NN
cord-341527-03rh966o	10	42	.	.	.
cord-341527-03rh966o	11	1	If	if	IN
cord-341527-03rh966o	11	2	dexmedetomidine	dexmedetomidine	NN
cord-341527-03rh966o	11	3	can	can	MD
cord-341527-03rh966o	11	4	improve	improve	VB
cord-341527-03rh966o	11	5	compliance	compliance	NN
cord-341527-03rh966o	11	6	with	with	IN
cord-341527-03rh966o	11	7	non	non	JJ
cord-341527-03rh966o	11	8	-	-	JJ
cord-341527-03rh966o	11	9	invasive	invasive	JJ
cord-341527-03rh966o	11	10	oxygen	oxygen	NN
cord-341527-03rh966o	11	11	support	support	NN
cord-341527-03rh966o	11	12	(	(	-LRB-
cord-341527-03rh966o	11	13	the	the	DT
cord-341527-03rh966o	11	14	current	current	JJ
cord-341527-03rh966o	11	15	recommended	recommend	VBD
cord-341527-03rh966o	11	16	first	first	JJ
cord-341527-03rh966o	11	17	-	-	HYPH
cord-341527-03rh966o	11	18	line	line	NN
cord-341527-03rh966o	11	19	therapy	therapy	NN
cord-341527-03rh966o	11	20	)	)	-RRB-
cord-341527-03rh966o	11	21	while	while	IN
cord-341527-03rh966o	11	22	promoting	promote	VBG
cord-341527-03rh966o	11	23	better	well	JJR
cord-341527-03rh966o	11	24	oxygenation	oxygenation	NN
cord-341527-03rh966o	11	25	,	,	,
cord-341527-03rh966o	11	26	it	-PRON-	PRP
cord-341527-03rh966o	11	27	may	may	MD
cord-341527-03rh966o	11	28	also	also	RB
cord-341527-03rh966o	11	29	decrease	decrease	VB
cord-341527-03rh966o	11	30	the	the	DT
cord-341527-03rh966o	11	31	need	need	NN
cord-341527-03rh966o	11	32	for	for	IN
cord-341527-03rh966o	11	33	mechanical	mechanical	JJ
cord-341527-03rh966o	11	34	ventilation	ventilation	NN
cord-341527-03rh966o	11	35	and	and	CC
cord-341527-03rh966o	11	36	thus	thus	RB
cord-341527-03rh966o	11	37	improve	improve	VB
cord-341527-03rh966o	11	38	mortality	mortality	NN
cord-341527-03rh966o	11	39	.	.	.
cord-341527-03rh966o	12	1	As	as	IN
cord-341527-03rh966o	12	2	of	of	IN
cord-341527-03rh966o	12	3	this	this	DT
cord-341527-03rh966o	12	4	writing	writing	NN
cord-341527-03rh966o	12	5	,	,	,
cord-341527-03rh966o	12	6	there	there	EX
cord-341527-03rh966o	12	7	have	have	VBP
cord-341527-03rh966o	12	8	been	be	VBN
cord-341527-03rh966o	12	9	over	over	IN
cord-341527-03rh966o	12	10	1,300,000	1,300,000	CD
cord-341527-03rh966o	12	11	confirmed	confirm	VBN
cord-341527-03rh966o	12	12	cases	case	NNS
cord-341527-03rh966o	12	13	of	of	IN
cord-341527-03rh966o	12	14	COVID-19	covid-19	CD
cord-341527-03rh966o	12	15	and	and	CC
cord-341527-03rh966o	12	16	80,000	80,000	CD
cord-341527-03rh966o	12	17	deaths	death	NNS
cord-341527-03rh966o	12	18	in	in	IN
cord-341527-03rh966o	12	19	the	the	DT
cord-341527-03rh966o	12	20	United	United	NNP
cord-341527-03rh966o	12	21	States	States	NNP
cord-341527-03rh966o	12	22	[	[	-LRB-
cord-341527-03rh966o	12	23	1	1	CD
cord-341527-03rh966o	12	24	]	]	-RRB-
cord-341527-03rh966o	12	25	.	.	.
cord-341527-03rh966o	13	1	While	while	IN
cord-341527-03rh966o	13	2	early	early	JJ
cord-341527-03rh966o	13	3	intubation	intubation	NN
cord-341527-03rh966o	13	4	was	be	VBD
cord-341527-03rh966o	13	5	the	the	DT
cord-341527-03rh966o	13	6	initial	initial	JJ
cord-341527-03rh966o	13	7	recommended	recommend	VBN
cord-341527-03rh966o	13	8	strategy	strategy	NN
cord-341527-03rh966o	13	9	for	for	IN
cord-341527-03rh966o	13	10	COVID-19	COVID-19	NNP
cord-341527-03rh966o	13	11	hypoxemia	hypoxemia	NN
cord-341527-03rh966o	13	12	,	,	,
cord-341527-03rh966o	13	13	a	a	DT
cord-341527-03rh966o	13	14	large	large	JJ
cord-341527-03rh966o	13	15	case	case	NN
cord-341527-03rh966o	13	16	series	series	NN
cord-341527-03rh966o	13	17	in	in	IN
cord-341527-03rh966o	13	18	the	the	DT
cord-341527-03rh966o	13	19	US	US	NNP
cord-341527-03rh966o	13	20	as	as	RB
cord-341527-03rh966o	13	21	well	well	RB
cord-341527-03rh966o	13	22	as	as	IN
cord-341527-03rh966o	13	23	data	datum	NNS
cord-341527-03rh966o	13	24	coming	come	VBG
cord-341527-03rh966o	13	25	out	out	IN
cord-341527-03rh966o	13	26	of	of	IN
cord-341527-03rh966o	13	27	Britain	Britain	NNP
cord-341527-03rh966o	13	28	,	,	,
cord-341527-03rh966o	13	29	China	China	NNP
cord-341527-03rh966o	13	30	,	,	,
cord-341527-03rh966o	13	31	and	and	CC
cord-341527-03rh966o	13	32	Italy	Italy	NNP
cord-341527-03rh966o	13	33	suggests	suggest	VBZ
cord-341527-03rh966o	13	34	a	a	DT
cord-341527-03rh966o	13	35	high	high	JJ
cord-341527-03rh966o	13	36	mortality	mortality	NN
cord-341527-03rh966o	13	37	for	for	IN
cord-341527-03rh966o	13	38	patients	patient	NNS
cord-341527-03rh966o	13	39	requiring	require	VBG
cord-341527-03rh966o	13	40	invasive	invasive	JJ
cord-341527-03rh966o	13	41	ventilation	ventilation	NN
cord-341527-03rh966o	13	42	[	[	-LRB-
cord-341527-03rh966o	13	43	2	2	CD
cord-341527-03rh966o	13	44	]	]	-RRB-
cord-341527-03rh966o	13	45	.	.	.
cord-341527-03rh966o	14	1	The	the	DT
cord-341527-03rh966o	14	2	National	National	NNP
cord-341527-03rh966o	14	3	Institute	Institute	NNP
cord-341527-03rh966o	14	4	of	of	IN
cord-341527-03rh966o	14	5	Health	Health	NNP
cord-341527-03rh966o	14	6	now	now	RB
cord-341527-03rh966o	14	7	recommends	recommend	VBZ
cord-341527-03rh966o	14	8	high	high	JJ
cord-341527-03rh966o	14	9	flow	flow	NN
cord-341527-03rh966o	14	10	nasal	nasal	NN
cord-341527-03rh966o	14	11	cannula	cannula	NN
cord-341527-03rh966o	14	12	(	(	-LRB-
cord-341527-03rh966o	14	13	HFNC	HFNC	NNP
cord-341527-03rh966o	14	14	)	)	-RRB-
cord-341527-03rh966o	14	15	as	as	IN
cord-341527-03rh966o	14	16	first	first	JJ
cord-341527-03rh966o	14	17	line	line	NN
cord-341527-03rh966o	14	18	oxygen	oxygen	NN
cord-341527-03rh966o	14	19	support	support	NN
cord-341527-03rh966o	14	20	[	[	-LRB-
cord-341527-03rh966o	14	21	3	3	CD
cord-341527-03rh966o	14	22	]	]	-RRB-
cord-341527-03rh966o	14	23	.	.	.
cord-341527-03rh966o	15	1	The	the	DT
cord-341527-03rh966o	15	2	following	following	JJ
cord-341527-03rh966o	15	3	case	case	NN
cord-341527-03rh966o	15	4	addresses	address	VBZ
cord-341527-03rh966o	15	5	the	the	DT
cord-341527-03rh966o	15	6	management	management	NN
cord-341527-03rh966o	15	7	of	of	IN
cord-341527-03rh966o	15	8	one	one	CD
cord-341527-03rh966o	15	9	patient	patient	NN
cord-341527-03rh966o	15	10	on	on	IN
cord-341527-03rh966o	15	11	HFNC	HFNC	NNP
cord-341527-03rh966o	15	12	,	,	,
cord-341527-03rh966o	15	13	with	with	IN
cord-341527-03rh966o	15	14	specific	specific	JJ
cord-341527-03rh966o	15	15	reference	reference	NN
cord-341527-03rh966o	15	16	to	to	IN
cord-341527-03rh966o	15	17	dexmedetomidine	dexmedetomidine	NNP
cord-341527-03rh966o	15	18	.	.	.
cord-341527-03rh966o	16	1	A	a	DT
cord-341527-03rh966o	16	2	58-year	58-year	JJ
cord-341527-03rh966o	16	3	-	-	HYPH
cord-341527-03rh966o	16	4	old	old	JJ
cord-341527-03rh966o	16	5	female	female	NN
cord-341527-03rh966o	16	6	with	with	IN
cord-341527-03rh966o	16	7	hypertension	hypertension	NN
cord-341527-03rh966o	16	8	presented	present	VBN
cord-341527-03rh966o	16	9	to	to	IN
cord-341527-03rh966o	16	10	a	a	DT
cord-341527-03rh966o	16	11	New	New	NNP
cord-341527-03rh966o	16	12	York	York	NNP
cord-341527-03rh966o	16	13	City	City	NNP
cord-341527-03rh966o	16	14	emergency	emergency	NN
cord-341527-03rh966o	16	15	department	department	NN
cord-341527-03rh966o	16	16	for	for	IN
cord-341527-03rh966o	16	17	shortness	shortness	NN
cord-341527-03rh966o	16	18	of	of	IN
cord-341527-03rh966o	16	19	breath	breath	NN
cord-341527-03rh966o	16	20	for	for	IN
cord-341527-03rh966o	16	21	one	one	CD
cord-341527-03rh966o	16	22	day	day	NN
cord-341527-03rh966o	16	23	in	in	IN
cord-341527-03rh966o	16	24	the	the	DT
cord-341527-03rh966o	16	25	setting	setting	NN
cord-341527-03rh966o	16	26	of	of	IN
cord-341527-03rh966o	16	27	known	know	VBN
cord-341527-03rh966o	16	28	COVID-19	covid-19	CD
cord-341527-03rh966o	16	29	diagnosed	diagnose	VBN
cord-341527-03rh966o	16	30	one	one	CD
cord-341527-03rh966o	16	31	week	week	NN
cord-341527-03rh966o	16	32	prior	prior	RB
cord-341527-03rh966o	16	33	.	.	.
cord-341527-03rh966o	17	1	Initial	initial	JJ
cord-341527-03rh966o	17	2	vital	vital	JJ
cord-341527-03rh966o	17	3	signs	sign	NNS
cord-341527-03rh966o	17	4	revealed	reveal	VBD
cord-341527-03rh966o	17	5	an	an	DT
cord-341527-03rh966o	17	6	SpO2	spo2	NN
cord-341527-03rh966o	17	7	of	of	IN
cord-341527-03rh966o	17	8	95	95	CD
cord-341527-03rh966o	17	9	%	%	NN
cord-341527-03rh966o	17	10	on	on	IN
cord-341527-03rh966o	17	11	room	room	NN
cord-341527-03rh966o	17	12	air	air	NN
cord-341527-03rh966o	17	13	.	.	.
cord-341527-03rh966o	18	1	On	on	IN
cord-341527-03rh966o	18	2	examination	examination	NN
cord-341527-03rh966o	18	3	,	,	,
cord-341527-03rh966o	18	4	the	the	DT
cord-341527-03rh966o	18	5	patient	patient	NN
cord-341527-03rh966o	18	6	was	be	VBD
cord-341527-03rh966o	18	7	tachypneic	tachypneic	NNS
cord-341527-03rh966o	18	8	.	.	.
cord-341527-03rh966o	19	1	Her	-PRON-	PRP$
cord-341527-03rh966o	19	2	chest	chest	NN
cord-341527-03rh966o	19	3	x	x	NN
cord-341527-03rh966o	19	4	-	-	NN
cord-341527-03rh966o	19	5	ray	ray	NN
cord-341527-03rh966o	19	6	showed	show	VBD
cord-341527-03rh966o	19	7	pulmonary	pulmonary	JJ
cord-341527-03rh966o	19	8	infiltrates	infiltrate	VBZ
cord-341527-03rh966o	19	9	consistent	consistent	JJ
cord-341527-03rh966o	19	10	with	with	IN
cord-341527-03rh966o	19	11	COVID-19	COVID-19	NNP
cord-341527-03rh966o	19	12	.	.	.
cord-341527-03rh966o	20	1	Initially	initially	RB
cord-341527-03rh966o	20	2	placed	place	VBN
cord-341527-03rh966o	20	3	on	on	IN
cord-341527-03rh966o	20	4	a	a	DT
cord-341527-03rh966o	20	5	non	non	JJ
cord-341527-03rh966o	20	6	-	-	JJ
cord-341527-03rh966o	20	7	rebreather	rebreather	JJ
cord-341527-03rh966o	20	8	mask	mask	NN
cord-341527-03rh966o	20	9	,	,	,
cord-341527-03rh966o	20	10	the	the	DT
cord-341527-03rh966o	20	11	patient	patient	NN
cord-341527-03rh966o	20	12	's	's	POS
cord-341527-03rh966o	20	13	SpO2	SpO2	NNS
cord-341527-03rh966o	20	14	gradually	gradually	RB
cord-341527-03rh966o	20	15	dropped	drop	VBD
cord-341527-03rh966o	20	16	and	and	CC
cord-341527-03rh966o	20	17	she	-PRON-	PRP
cord-341527-03rh966o	20	18	was	be	VBD
cord-341527-03rh966o	20	19	started	start	VBN
cord-341527-03rh966o	20	20	on	on	IN
cord-341527-03rh966o	20	21	HFNC	HFNC	NNP
cord-341527-03rh966o	20	22	(	(	-LRB-
cord-341527-03rh966o	20	23	40L	40l	CD
cord-341527-03rh966o	20	24	and	and	CC
cord-341527-03rh966o	20	25	88	88	CD
cord-341527-03rh966o	20	26	%	%	NN
cord-341527-03rh966o	20	27	FiO2	FiO2	NNS
cord-341527-03rh966o	20	28	)	)	-RRB-
cord-341527-03rh966o	20	29	.	.	.
cord-341527-03rh966o	21	1	On	on	IN
cord-341527-03rh966o	21	2	day	day	NN
cord-341527-03rh966o	21	3	2	2	CD
cord-341527-03rh966o	21	4	1	1	CD
cord-341527-03rh966o	21	5	,	,	,
cord-341527-03rh966o	21	6	oxygen	oxygen	NN
cord-341527-03rh966o	21	7	requirements	requirement	NNS
cord-341527-03rh966o	21	8	continued	continue	VBD
cord-341527-03rh966o	21	9	to	to	TO
cord-341527-03rh966o	21	10	increase	increase	VB
cord-341527-03rh966o	21	11	and	and	CC
cord-341527-03rh966o	21	12	her	-PRON-	PRP$
cord-341527-03rh966o	21	13	HFNC	HFNC	NNP
cord-341527-03rh966o	21	14	was	be	VBD
cord-341527-03rh966o	21	15	titrated	titrate	VBN
cord-341527-03rh966o	21	16	up	up	RP
cord-341527-03rh966o	21	17	to	to	TO
cord-341527-03rh966o	21	18	100	100	CD
cord-341527-03rh966o	21	19	%	%	NN
cord-341527-03rh966o	21	20	at	at	IN
cord-341527-03rh966o	21	21	60L	60L	NNP
cord-341527-03rh966o	21	22	,	,	,
cord-341527-03rh966o	21	23	with	with	IN
cord-341527-03rh966o	21	24	a	a	DT
cord-341527-03rh966o	21	25	non	non	JJ
cord-341527-03rh966o	21	26	-	-	JJ
cord-341527-03rh966o	21	27	rebreather	rebreather	JJ
cord-341527-03rh966o	21	28	placed	place	VBN
cord-341527-03rh966o	21	29	over	over	IN
cord-341527-03rh966o	21	30	it	-PRON-	PRP
cord-341527-03rh966o	21	31	.	.	.
cord-341527-03rh966o	22	1	On	on	IN
cord-341527-03rh966o	22	2	day	day	NN
cord-341527-03rh966o	22	3	8	8	CD
cord-341527-03rh966o	22	4	(	(	-LRB-
cord-341527-03rh966o	22	5	day	day	NN
cord-341527-03rh966o	22	6	15	15	CD
cord-341527-03rh966o	22	7	of	of	IN
cord-341527-03rh966o	22	8	illness	illness	NN
cord-341527-03rh966o	22	9	by	by	IN
cord-341527-03rh966o	22	10	symptomatology	symptomatology	NN
cord-341527-03rh966o	22	11	)	)	-RRB-
cord-341527-03rh966o	22	12	,	,	,
cord-341527-03rh966o	22	13	SpO2	SpO2	NNP
cord-341527-03rh966o	22	14	worsened	worsen	VBD
cord-341527-03rh966o	22	15	from	from	IN
cord-341527-03rh966o	22	16	92	92	CD
cord-341527-03rh966o	22	17	%	%	NN
cord-341527-03rh966o	22	18	to	to	IN
cord-341527-03rh966o	22	19	84	84	CD
cord-341527-03rh966o	22	20	%	%	NN
cord-341527-03rh966o	22	21	,	,	,
cord-341527-03rh966o	22	22	despite	despite	IN
cord-341527-03rh966o	22	23	J	J	NNP
cord-341527-03rh966o	22	24	o	o	NNP
cord-341527-03rh966o	22	25	u	u	NN
cord-341527-03rh966o	22	26	r	r	NN
cord-341527-03rh966o	22	27	n	n	NN
cord-341527-03rh966o	22	28	a	a	DT
cord-341527-03rh966o	22	29	l	l	NN
cord-341527-03rh966o	22	30	P	p	NN
cord-341527-03rh966o	22	31	r	r	NN
cord-341527-03rh966o	22	32	e	e	NN
cord-341527-03rh966o	22	33	-p	-p	NN
cord-341527-03rh966o	22	34	r	r	NN
cord-341527-03rh966o	23	1	o	o	UH
cord-341527-03rh966o	24	1	o	o	UH
cord-341527-03rh966o	24	2	f	f	NN
cord-341527-03rh966o	24	3	maximal	maximal	JJ
cord-341527-03rh966o	24	4	oxygen	oxygen	NN
cord-341527-03rh966o	24	5	support	support	NN
cord-341527-03rh966o	24	6	.	.	.
cord-341527-03rh966o	25	1	The	the	DT
cord-341527-03rh966o	25	2	patient	patient	NN
cord-341527-03rh966o	25	3	appeared	appear	VBD
cord-341527-03rh966o	25	4	uncomfortable	uncomfortable	JJ
cord-341527-03rh966o	25	5	,	,	,
cord-341527-03rh966o	25	6	intermittently	intermittently	RB
cord-341527-03rh966o	25	7	attempting	attempt	VBG
cord-341527-03rh966o	25	8	to	to	TO
cord-341527-03rh966o	25	9	displace	displace	VB
cord-341527-03rh966o	25	10	her	-PRON-	PRP$
cord-341527-03rh966o	25	11	oxygen	oxygen	NN
cord-341527-03rh966o	25	12	devices	device	NNS
cord-341527-03rh966o	25	13	.	.	.
cord-341527-03rh966o	26	1	A	a	DT
cord-341527-03rh966o	26	2	dexmedetomidine	dexmedetomidine	JJ
cord-341527-03rh966o	26	3	infusion	infusion	NN
cord-341527-03rh966o	26	4	was	be	VBD
cord-341527-03rh966o	26	5	initiated	initiate	VBN
cord-341527-03rh966o	26	6	,	,	,
cord-341527-03rh966o	26	7	after	after	IN
cord-341527-03rh966o	26	8	which	which	WDT
cord-341527-03rh966o	26	9	saturations	saturation	NNS
cord-341527-03rh966o	26	10	increased	increase	VBD
cord-341527-03rh966o	26	11	,	,	,
cord-341527-03rh966o	26	12	she	-PRON-	PRP
cord-341527-03rh966o	26	13	appeared	appear	VBD
cord-341527-03rh966o	26	14	more	more	RBR
cord-341527-03rh966o	26	15	comfortable	comfortable	JJ
cord-341527-03rh966o	26	16	,	,	,
cord-341527-03rh966o	26	17	and	and	CC
cord-341527-03rh966o	26	18	she	-PRON-	PRP
cord-341527-03rh966o	26	19	remained	remain	VBD
cord-341527-03rh966o	26	20	compliant	compliant	JJ
cord-341527-03rh966o	26	21	with	with	IN
cord-341527-03rh966o	26	22	her	-PRON-	PRP$
cord-341527-03rh966o	26	23	oxygen	oxygen	NN
cord-341527-03rh966o	26	24	devices	device	NNS
cord-341527-03rh966o	26	25	.	.	.
cord-341527-03rh966o	27	1	Her	-PRON-	PRP$
cord-341527-03rh966o	27	2	SpO2	SpO2	NNS
cord-341527-03rh966o	27	3	remained	remain	VBD
cord-341527-03rh966o	27	4	in	in	IN
cord-341527-03rh966o	27	5	the	the	DT
cord-341527-03rh966o	27	6	86	86	CD
cord-341527-03rh966o	27	7	%	%	NN
cord-341527-03rh966o	27	8	to	to	TO
cord-341527-03rh966o	27	9	100	100	CD
cord-341527-03rh966o	27	10	%	%	NN
cord-341527-03rh966o	27	11	range	range	NN
cord-341527-03rh966o	27	12	and	and	CC
cord-341527-03rh966o	27	13	on	on	IN
cord-341527-03rh966o	27	14	day	day	NN
cord-341527-03rh966o	27	15	12	12	CD
cord-341527-03rh966o	27	16	,	,	,
cord-341527-03rh966o	27	17	she	-PRON-	PRP
cord-341527-03rh966o	27	18	was	be	VBD
cord-341527-03rh966o	27	19	transitioned	transition	VBN
cord-341527-03rh966o	27	20	from	from	IN
cord-341527-03rh966o	27	21	HFNC	HFNC	NNP
cord-341527-03rh966o	27	22	to	to	TO
cord-341527-03rh966o	27	23	nasal	nasal	VB
cord-341527-03rh966o	27	24	cannula	cannula	NN
cord-341527-03rh966o	27	25	(	(	-LRB-
cord-341527-03rh966o	27	26	6L	6L	NNP
cord-341527-03rh966o	27	27	)	)	-RRB-
cord-341527-03rh966o	27	28	and	and	CC
cord-341527-03rh966o	27	29	admitted	admit	VBN
cord-341527-03rh966o	27	30	.	.	.
cord-341527-03rh966o	28	1	At	at	IN
cord-341527-03rh966o	28	2	the	the	DT
cord-341527-03rh966o	28	3	time	time	NN
cord-341527-03rh966o	28	4	of	of	IN
cord-341527-03rh966o	28	5	this	this	DT
cord-341527-03rh966o	28	6	writing	writing	NN
cord-341527-03rh966o	28	7	,	,	,
cord-341527-03rh966o	28	8	she	-PRON-	PRP
cord-341527-03rh966o	28	9	remains	remain	VBZ
cord-341527-03rh966o	28	10	on	on	IN
cord-341527-03rh966o	28	11	nasal	nasal	NN
cord-341527-03rh966o	28	12	cannula	cannula	NN
cord-341527-03rh966o	28	13	and	and	CC
cord-341527-03rh966o	28	14	is	be	VBZ
cord-341527-03rh966o	28	15	doing	do	VBG
cord-341527-03rh966o	28	16	well	well	RB
cord-341527-03rh966o	28	17	(	(	-LRB-
cord-341527-03rh966o	28	18	ambulating	ambulate	VBG
cord-341527-03rh966o	28	19	,	,	,
cord-341527-03rh966o	28	20	tolerating	tolerate	VBG
cord-341527-03rh966o	28	21	a	a	DT
cord-341527-03rh966o	28	22	regular	regular	JJ
cord-341527-03rh966o	28	23	diet	diet	NN
cord-341527-03rh966o	28	24	and	and	CC
cord-341527-03rh966o	28	25	with	with	IN
cord-341527-03rh966o	28	26	a	a	DT
cord-341527-03rh966o	28	27	normal	normal	JJ
cord-341527-03rh966o	28	28	mental	mental	JJ
cord-341527-03rh966o	28	29	status	status	NN
cord-341527-03rh966o	28	30	)	)	-RRB-
cord-341527-03rh966o	28	31	.	.	.
cord-341527-03rh966o	29	1	Severe	severe	JJ
cord-341527-03rh966o	29	2	COVID-19	covid-19	JJ
cord-341527-03rh966o	29	3	pulmonary	pulmonary	JJ
cord-341527-03rh966o	29	4	disease	disease	NN
cord-341527-03rh966o	29	5	is	be	VBZ
cord-341527-03rh966o	29	6	characterized	characterize	VBN
cord-341527-03rh966o	29	7	by	by	IN
cord-341527-03rh966o	29	8	hypoxemia	hypoxemia	NN
cord-341527-03rh966o	29	9	and	and	CC
cord-341527-03rh966o	29	10	requires	require	VBZ
cord-341527-03rh966o	29	11	a	a	DT
cord-341527-03rh966o	29	12	multimodal	multimodal	NN
cord-341527-03rh966o	29	13	approach	approach	NN
cord-341527-03rh966o	29	14	.	.	.
cord-341527-03rh966o	30	1	Our	-PRON-	PRP$
cord-341527-03rh966o	30	2	patient	patient	NN
cord-341527-03rh966o	30	3	received	receive	VBD
cord-341527-03rh966o	30	4	the	the	DT
cord-341527-03rh966o	30	5	standard	standard	JJ
cord-341527-03rh966o	30	6	medical	medical	JJ
cord-341527-03rh966o	30	7	therapy	therapy	NN
cord-341527-03rh966o	30	8	endorsed	endorse	VBN
cord-341527-03rh966o	30	9	by	by	IN
cord-341527-03rh966o	30	10	our	-PRON-	PRP$
cord-341527-03rh966o	30	11	department	department	NN
cord-341527-03rh966o	30	12	at	at	IN
cord-341527-03rh966o	30	13	the	the	DT
cord-341527-03rh966o	30	14	time	time	NN
cord-341527-03rh966o	30	15	of	of	IN
cord-341527-03rh966o	30	16	her	-PRON-	PRP$
cord-341527-03rh966o	30	17	care	care	NN
cord-341527-03rh966o	30	18	:	:	:
cord-341527-03rh966o	30	19	supplemental	supplemental	JJ
cord-341527-03rh966o	30	20	oxygen	oxygen	NN
cord-341527-03rh966o	30	21	,	,	,
cord-341527-03rh966o	30	22	azithromycin	azithromycin	NN
cord-341527-03rh966o	30	23	,	,	,
cord-341527-03rh966o	30	24	anticoagulation	anticoagulation	NN
cord-341527-03rh966o	30	25	and	and	CC
cord-341527-03rh966o	30	26	corticosteroids	corticosteroid	NNS
cord-341527-03rh966o	30	27	.	.	.
cord-341527-03rh966o	31	1	She	-PRON-	PRP
cord-341527-03rh966o	31	2	was	be	VBD
cord-341527-03rh966o	31	3	placed	place	VBN
cord-341527-03rh966o	31	4	in	in	IN
cord-341527-03rh966o	31	5	trials	trial	NNS
cord-341527-03rh966o	31	6	for	for	IN
cord-341527-03rh966o	31	7	tocilizumab	tocilizumab	JJ
cord-341527-03rh966o	31	8	and	and	CC
cord-341527-03rh966o	31	9	convalescent	convalescent	JJ
cord-341527-03rh966o	31	10	plasma	plasma	NN
cord-341527-03rh966o	31	11	and	and	CC
cord-341527-03rh966o	31	12	received	receive	VBD
cord-341527-03rh966o	31	13	chest	chest	NN
cord-341527-03rh966o	31	14	physical	physical	JJ
cord-341527-03rh966o	31	15	therapy	therapy	NN
cord-341527-03rh966o	31	16	and	and	CC
cord-341527-03rh966o	31	17	awake	awake	JJ
cord-341527-03rh966o	31	18	intermittent	intermittent	JJ
cord-341527-03rh966o	31	19	proning	proning	NN
cord-341527-03rh966o	31	20	.	.	.
cord-341527-03rh966o	32	1	However	however	RB
cord-341527-03rh966o	32	2	,	,	,
cord-341527-03rh966o	32	3	there	there	EX
cord-341527-03rh966o	32	4	are	be	VBP
cord-341527-03rh966o	32	5	several	several	JJ
cord-341527-03rh966o	32	6	reasons	reason	NNS
cord-341527-03rh966o	32	7	to	to	TO
cord-341527-03rh966o	32	8	believe	believe	VB
cord-341527-03rh966o	32	9	dexmedetomidine	dexmedetomidine	NNP
cord-341527-03rh966o	32	10	contributed	contribute	VBD
cord-341527-03rh966o	32	11	significantly	significantly	RB
cord-341527-03rh966o	32	12	to	to	IN
cord-341527-03rh966o	32	13	her	-PRON-	PRP
cord-341527-03rh966o	32	14	course	course	NN
cord-341527-03rh966o	32	15	.	.	.
cord-341527-03rh966o	33	1	As	as	IN
cord-341527-03rh966o	33	2	Figure	figure	NN
cord-341527-03rh966o	33	3	1	1	CD
cord-341527-03rh966o	33	4	demonstrates	demonstrate	VBZ
cord-341527-03rh966o	33	5	,	,	,
cord-341527-03rh966o	33	6	during	during	IN
cord-341527-03rh966o	33	7	the	the	DT
cord-341527-03rh966o	33	8	first	first	JJ
cord-341527-03rh966o	33	9	seven	seven	CD
cord-341527-03rh966o	33	10	days	day	NNS
cord-341527-03rh966o	33	11	her	-PRON-	PRP$
cord-341527-03rh966o	33	12	SpO2	SpO2	NNS
cord-341527-03rh966o	33	13	generally	generally	RB
cord-341527-03rh966o	33	14	remained	remain	VBD
cord-341527-03rh966o	33	15	>	>	XX
cord-341527-03rh966o	33	16	90	90	CD
cord-341527-03rh966o	33	17	%	%	NN
cord-341527-03rh966o	33	18	.	.	.
cord-341527-03rh966o	34	1	Nevertheless	nevertheless	RB
cord-341527-03rh966o	34	2	,	,	,
cord-341527-03rh966o	34	3	her	-PRON-	PRP$
cord-341527-03rh966o	34	4	chart	chart	NN
cord-341527-03rh966o	34	5	notes	note	VBZ
cord-341527-03rh966o	34	6	worsening	worsen	VBG
cord-341527-03rh966o	34	7	tachypnea	tachypnea	NNP
cord-341527-03rh966o	34	8	,	,	,
cord-341527-03rh966o	34	9	titration	titration	NN
cord-341527-03rh966o	34	10	of	of	IN
cord-341527-03rh966o	34	11	HFNC	HFNC	NNP
cord-341527-03rh966o	34	12	to	to	IN
cord-341527-03rh966o	34	13	maximal	maximal	JJ
cord-341527-03rh966o	34	14	settings	setting	NNS
cord-341527-03rh966o	34	15	and	and	CC
cord-341527-03rh966o	34	16	eventually	eventually	RB
cord-341527-03rh966o	34	17	requiring	require	VBG
cord-341527-03rh966o	34	18	a	a	DT
cord-341527-03rh966o	34	19	non	non	JJ
cord-341527-03rh966o	34	20	-	-	JJ
cord-341527-03rh966o	34	21	rebreather	rebreather	JJ
cord-341527-03rh966o	34	22	mask	mask	NN
cord-341527-03rh966o	34	23	placed	place	VBN
cord-341527-03rh966o	34	24	over	over	IN
cord-341527-03rh966o	34	25	her	-PRON-	PRP$
cord-341527-03rh966o	34	26	HFNC	HFNC	NNP
cord-341527-03rh966o	34	27	.	.	.
cord-341527-03rh966o	35	1	As	as	IN
cord-341527-03rh966o	35	2	SpO2	SpO2	NNP
cord-341527-03rh966o	35	3	dropped	drop	VBD
cord-341527-03rh966o	35	4	,	,	,
cord-341527-03rh966o	35	5	she	-PRON-	PRP
cord-341527-03rh966o	35	6	became	become	VBD
cord-341527-03rh966o	35	7	agitated	agitated	JJ
cord-341527-03rh966o	35	8	and	and	CC
cord-341527-03rh966o	35	9	at	at	IN
cord-341527-03rh966o	35	10	risk	risk	NN
cord-341527-03rh966o	35	11	of	of	IN
cord-341527-03rh966o	35	12	dislodging	dislodge	VBG
cord-341527-03rh966o	35	13	her	-PRON-	PRP$
cord-341527-03rh966o	35	14	oxygen	oxygen	NN
cord-341527-03rh966o	35	15	devices	device	NNS
cord-341527-03rh966o	35	16	.	.	.
cord-341527-03rh966o	36	1	Intubation	intubation	NN
cord-341527-03rh966o	36	2	was	be	VBD
cord-341527-03rh966o	36	3	strongly	strongly	RB
cord-341527-03rh966o	36	4	J	J	NNP
cord-341527-03rh966o	36	5	o	o	NN
cord-341527-03rh966o	36	6	u	u	NN
cord-341527-03rh966o	36	7	r	r	NN
cord-341527-03rh966o	36	8	n	n	NN
cord-341527-03rh966o	36	9	a	a	DT
cord-341527-03rh966o	36	10	l	l	NN
cord-341527-03rh966o	36	11	P	p	NN
cord-341527-03rh966o	36	12	r	r	NN
cord-341527-03rh966o	36	13	e	e	NN
cord-341527-03rh966o	36	14	-p	-p	NN
cord-341527-03rh966o	37	1	r	r	NNP
cord-341527-03rh966o	37	2	o	o	NN
cord-341527-03rh966o	37	3	o	o	NN
cord-341527-03rh966o	37	4	f	f	NN
cord-341527-03rh966o	37	5	considered	consider	VBN
cord-341527-03rh966o	37	6	.	.	.
cord-341527-03rh966o	38	1	However	however	RB
cord-341527-03rh966o	38	2	,	,	,
cord-341527-03rh966o	38	3	with	with	IN
cord-341527-03rh966o	38	4	departmental	departmental	JJ
cord-341527-03rh966o	38	5	preference	preference	NN
cord-341527-03rh966o	38	6	toward	toward	IN
cord-341527-03rh966o	38	7	delayed	delay	VBN
cord-341527-03rh966o	38	8	intubation	intubation	NN
cord-341527-03rh966o	38	9	2	2	CD
cord-341527-03rh966o	38	10	,	,	,
cord-341527-03rh966o	38	11	consensus	consensus	NN
cord-341527-03rh966o	38	12	developed	develop	VBD
cord-341527-03rh966o	38	13	to	to	TO
cord-341527-03rh966o	38	14	administer	administer	VB
cord-341527-03rh966o	38	15	dexmedetomidine	dexmedetomidine	NN
cord-341527-03rh966o	38	16	instead	instead	RB
cord-341527-03rh966o	38	17	.	.	.
cord-341527-03rh966o	39	1	After	after	IN
cord-341527-03rh966o	39	2	,	,	,
cord-341527-03rh966o	39	3	our	-PRON-	PRP$
cord-341527-03rh966o	39	4	patient	patient	NN
cord-341527-03rh966o	39	5	's	's	POS
cord-341527-03rh966o	39	6	SpO2	SpO2	NNP
cord-341527-03rh966o	39	7	increased	increase	VBD
cord-341527-03rh966o	39	8	from	from	IN
cord-341527-03rh966o	39	9	84	84	CD
cord-341527-03rh966o	39	10	%	%	NN
cord-341527-03rh966o	39	11	to	to	TO
cord-341527-03rh966o	39	12	100	100	CD
cord-341527-03rh966o	39	13	%	%	NN
cord-341527-03rh966o	39	14	,	,	,
cord-341527-03rh966o	39	15	with	with	IN
cord-341527-03rh966o	39	16	no	no	DT
cord-341527-03rh966o	39	17	other	other	JJ
cord-341527-03rh966o	39	18	intervention	intervention	NN
cord-341527-03rh966o	39	19	taking	take	VBG
cord-341527-03rh966o	39	20	place	place	NN
cord-341527-03rh966o	39	21	at	at	IN
cord-341527-03rh966o	39	22	the	the	DT
cord-341527-03rh966o	39	23	time	time	NN
cord-341527-03rh966o	39	24	3	3	CD
cord-341527-03rh966o	39	25	.	.	.
cord-341527-03rh966o	40	1	Given	give	VBN
cord-341527-03rh966o	40	2	the	the	DT
cord-341527-03rh966o	40	3	context	context	NN
cord-341527-03rh966o	40	4	of	of	IN
cord-341527-03rh966o	40	5	gradually	gradually	RB
cord-341527-03rh966o	40	6	worsening	worsen	VBG
cord-341527-03rh966o	40	7	hypoxemia	hypoxemia	NN
cord-341527-03rh966o	40	8	,	,	,
cord-341527-03rh966o	40	9	timing	timing	NN
cord-341527-03rh966o	40	10	of	of	IN
cord-341527-03rh966o	40	11	administration	administration	NN
cord-341527-03rh966o	40	12	,	,	,
cord-341527-03rh966o	40	13	subsequent	subsequent	JJ
cord-341527-03rh966o	40	14	improvement	improvement	NN
cord-341527-03rh966o	40	15	in	in	IN
cord-341527-03rh966o	40	16	SpO2	SpO2	NNP
cord-341527-03rh966o	40	17	and	and	CC
cord-341527-03rh966o	40	18	observed	observe	VBD
cord-341527-03rh966o	40	19	change	change	NN
cord-341527-03rh966o	40	20	in	in	IN
cord-341527-03rh966o	40	21	mental	mental	JJ
cord-341527-03rh966o	40	22	status	status	NN
cord-341527-03rh966o	40	23	(	(	-LRB-
cord-341527-03rh966o	40	24	from	from	IN
cord-341527-03rh966o	40	25	agitated	agitated	JJ
cord-341527-03rh966o	40	26	to	to	TO
cord-341527-03rh966o	40	27	calm	calm	VB
cord-341527-03rh966o	40	28	)	)	-RRB-
cord-341527-03rh966o	40	29	,	,	,
cord-341527-03rh966o	40	30	dexmedetomidine	dexmedetomidine	NNP
cord-341527-03rh966o	40	31	appeared	appear	VBD
cord-341527-03rh966o	40	32	to	to	TO
cord-341527-03rh966o	40	33	play	play	VB
cord-341527-03rh966o	40	34	a	a	DT
cord-341527-03rh966o	40	35	significant	significant	JJ
cord-341527-03rh966o	40	36	role	role	NN
cord-341527-03rh966o	40	37	.	.	.
cord-341527-03rh966o	41	1	The	the	DT
cord-341527-03rh966o	41	2	patient	patient	NN
cord-341527-03rh966o	41	3	avoided	avoid	VBD
cord-341527-03rh966o	41	4	intubation	intubation	NN
cord-341527-03rh966o	41	5	,	,	,
cord-341527-03rh966o	41	6	now	now	RB
cord-341527-03rh966o	41	7	has	have	VBZ
cord-341527-03rh966o	41	8	a	a	DT
cord-341527-03rh966o	41	9	stable	stable	JJ
cord-341527-03rh966o	41	10	SpO2	SpO2	NNS
cord-341527-03rh966o	41	11	on	on	IN
cord-341527-03rh966o	41	12	nasal	nasal	NN
cord-341527-03rh966o	41	13	cannula	cannula	NN
cord-341527-03rh966o	41	14	and	and	CC
cord-341527-03rh966o	41	15	is	be	VBZ
cord-341527-03rh966o	41	16	not	not	RB
cord-341527-03rh966o	41	17	in	in	IN
cord-341527-03rh966o	41	18	multi	multi	JJ
cord-341527-03rh966o	41	19	-	-	JJ
cord-341527-03rh966o	41	20	system	system	JJ
cord-341527-03rh966o	41	21	organ	organ	NN
cord-341527-03rh966o	41	22	failure	failure	NN
cord-341527-03rh966o	41	23	,	,	,
cord-341527-03rh966o	41	24	a	a	DT
cord-341527-03rh966o	41	25	significant	significant	JJ
cord-341527-03rh966o	41	26	victory	victory	NN
cord-341527-03rh966o	41	27	considering	consider	VBG
cord-341527-03rh966o	41	28	the	the	DT
cord-341527-03rh966o	41	29	alternative	alternative	NN
cord-341527-03rh966o	41	30	.	.	.
cord-341527-03rh966o	42	1	The	the	DT
cord-341527-03rh966o	42	2	pharmacokinetics	pharmacokinetic	NNS
cord-341527-03rh966o	42	3	of	of	IN
cord-341527-03rh966o	42	4	dexmedetomidine	dexmedetomidine	NNP
cord-341527-03rh966o	42	5	make	make	VB
cord-341527-03rh966o	42	6	it	-PRON-	PRP
cord-341527-03rh966o	42	7	ideal	ideal	JJ
cord-341527-03rh966o	42	8	in	in	IN
cord-341527-03rh966o	42	9	nonintubated	nonintubated	JJ
cord-341527-03rh966o	42	10	COVID-19	COVID-19	NNP
cord-341527-03rh966o	42	11	patients	patient	NNS
cord-341527-03rh966o	42	12	.	.	.
cord-341527-03rh966o	43	1	It	-PRON-	PRP
cord-341527-03rh966o	43	2	has	have	VBZ
cord-341527-03rh966o	43	3	a	a	DT
cord-341527-03rh966o	43	4	minimal	minimal	JJ
cord-341527-03rh966o	43	5	effect	effect	NN
cord-341527-03rh966o	43	6	on	on	IN
cord-341527-03rh966o	43	7	respiratory	respiratory	JJ
cord-341527-03rh966o	43	8	drive	drive	NN
cord-341527-03rh966o	43	9	,	,	,
cord-341527-03rh966o	43	10	a	a	DT
cord-341527-03rh966o	43	11	rapid	rapid	JJ
cord-341527-03rh966o	43	12	onset	onset	NN
cord-341527-03rh966o	43	13	and	and	CC
cord-341527-03rh966o	43	14	elimination	elimination	NN
cord-341527-03rh966o	43	15	and	and	CC
cord-341527-03rh966o	43	16	is	be	VBZ
cord-341527-03rh966o	43	17	easily	easily	RB
cord-341527-03rh966o	43	18	titratable	titratable	JJ
cord-341527-03rh966o	43	19	[	[	-LRB-
cord-341527-03rh966o	43	20	4	4	CD
cord-341527-03rh966o	43	21	]	]	-RRB-
cord-341527-03rh966o	43	22	.	.	.
cord-341527-03rh966o	44	1	Its	-PRON-	PRP$
cord-341527-03rh966o	44	2	side	side	NN
cord-341527-03rh966o	44	3	effect	effect	NN
cord-341527-03rh966o	44	4	of	of	IN
cord-341527-03rh966o	44	5	bradycardia	bradycardia	NN
cord-341527-03rh966o	44	6	appears	appear	VBZ
cord-341527-03rh966o	44	7	to	to	TO
cord-341527-03rh966o	44	8	be	be	VB
cord-341527-03rh966o	44	9	well	well	RB
cord-341527-03rh966o	44	10	tolerated	tolerate	VBN
cord-341527-03rh966o	44	11	.	.	.
cord-341527-03rh966o	45	1	On	on	IN
cord-341527-03rh966o	45	2	a	a	DT
cord-341527-03rh966o	45	3	behavioral	behavioral	JJ
cord-341527-03rh966o	45	4	level	level	NN
cord-341527-03rh966o	45	5	,	,	,
cord-341527-03rh966o	45	6	patients	patient	NNS
cord-341527-03rh966o	45	7	with	with	IN
cord-341527-03rh966o	45	8	worsening	worsen	VBG
cord-341527-03rh966o	45	9	hypoxia	hypoxia	NN
cord-341527-03rh966o	45	10	are	be	VBP
cord-341527-03rh966o	45	11	often	often	RB
cord-341527-03rh966o	45	12	very	very	RB
cord-341527-03rh966o	45	13	anxious	anxious	JJ
cord-341527-03rh966o	45	14	and	and	CC
cord-341527-03rh966o	45	15	prone	prone	JJ
cord-341527-03rh966o	45	16	to	to	IN
cord-341527-03rh966o	45	17	agitation	agitation	NN
cord-341527-03rh966o	45	18	.	.	.
cord-341527-03rh966o	46	1	This	this	DT
cord-341527-03rh966o	46	2	becomes	become	VBZ
cord-341527-03rh966o	46	3	especially	especially	RB
cord-341527-03rh966o	46	4	dangerous	dangerous	JJ
cord-341527-03rh966o	46	5	when	when	WRB
cord-341527-03rh966o	46	6	fully	fully	RB
cord-341527-03rh966o	46	7	dependent	dependent	JJ
cord-341527-03rh966o	46	8	on	on	IN
cord-341527-03rh966o	46	9	supplemental	supplemental	JJ
cord-341527-03rh966o	46	10	oxygen	oxygen	NN
cord-341527-03rh966o	46	11	,	,	,
cord-341527-03rh966o	46	12	where	where	WRB
cord-341527-03rh966o	46	13	acute	acute	JJ
cord-341527-03rh966o	46	14	decline	decline	NN
cord-341527-03rh966o	46	15	from	from	IN
cord-341527-03rh966o	46	16	dislodgement	dislodgement	NN
cord-341527-03rh966o	46	17	of	of	IN
cord-341527-03rh966o	46	18	support	support	NN
cord-341527-03rh966o	46	19	devices	device	NNS
cord-341527-03rh966o	46	20	is	be	VBZ
cord-341527-03rh966o	46	21	always	always	RB
cord-341527-03rh966o	46	22	a	a	DT
cord-341527-03rh966o	46	23	concern	concern	NN
cord-341527-03rh966o	46	24	.	.	.
cord-341527-03rh966o	47	1	Dexmedetomidine	Dexmedetomidine	NNP
cord-341527-03rh966o	47	2	has	have	VBZ
cord-341527-03rh966o	47	3	been	be	VBN
cord-341527-03rh966o	47	4	shown	show	VBN
cord-341527-03rh966o	47	5	in	in	IN
cord-341527-03rh966o	47	6	randomized	randomized	JJ
cord-341527-03rh966o	47	7	controlled	control	VBN
cord-341527-03rh966o	47	8	trials	trial	NNS
cord-341527-03rh966o	47	9	to	to	TO
cord-341527-03rh966o	47	10	decrease	decrease	VB
cord-341527-03rh966o	47	11	agitated	agitated	JJ
cord-341527-03rh966o	47	12	delirium	delirium	NN
cord-341527-03rh966o	47	13	in	in	IN
cord-341527-03rh966o	47	14	critically	critically	RB
cord-341527-03rh966o	47	15	ill	ill	JJ
cord-341527-03rh966o	47	16	patients	patient	NNS
cord-341527-03rh966o	47	17	[	[	-LRB-
cord-341527-03rh966o	47	18	5	5	CD
cord-341527-03rh966o	47	19	]	]	-RRB-
cord-341527-03rh966o	47	20	.	.	.
cord-341527-03rh966o	48	1	This	this	DT
cord-341527-03rh966o	48	2	benefit	benefit	NN
cord-341527-03rh966o	48	3	is	be	VBZ
cord-341527-03rh966o	48	4	likely	likely	RB
cord-341527-03rh966o	48	5	amplified	amplify	VBN
cord-341527-03rh966o	48	6	in	in	IN
cord-341527-03rh966o	48	7	elderly	elderly	JJ
cord-341527-03rh966o	48	8	populations	population	NNS
cord-341527-03rh966o	48	9	,	,	,
cord-341527-03rh966o	48	10	who	who	WP
cord-341527-03rh966o	48	11	have	have	VBP
cord-341527-03rh966o	48	12	higher	high	JJR
cord-341527-03rh966o	48	13	mortality	mortality	NN
cord-341527-03rh966o	48	14	and	and	CC
cord-341527-03rh966o	48	15	baseline	baseline	JJ
cord-341527-03rh966o	48	16	conditions	condition	NNS
cord-341527-03rh966o	48	17	that	that	WDT
cord-341527-03rh966o	48	18	predispose	predispose	VBP
cord-341527-03rh966o	48	19	them	-PRON-	PRP
cord-341527-03rh966o	48	20	to	to	IN
cord-341527-03rh966o	48	21	delirium	delirium	NN
cord-341527-03rh966o	48	22	and	and	CC
cord-341527-03rh966o	48	23	noncompliance	noncompliance	NN
cord-341527-03rh966o	48	24	with	with	IN
cord-341527-03rh966o	48	25	HFNC	HFNC	NNP
cord-341527-03rh966o	48	26	.	.	.
cord-341527-03rh966o	49	1	Dexmedetomidine	Dexmedetomidine	NNP
cord-341527-03rh966o	49	2	may	may	MD
cord-341527-03rh966o	49	3	promote	promote	VB
cord-341527-03rh966o	49	4	oxygenation	oxygenation	NN
cord-341527-03rh966o	49	5	on	on	IN
cord-341527-03rh966o	49	6	a	a	DT
cord-341527-03rh966o	49	7	physiologic	physiologic	JJ
cord-341527-03rh966o	49	8	level	level	NN
cord-341527-03rh966o	49	9	as	as	RB
cord-341527-03rh966o	49	10	well	well	RB
cord-341527-03rh966o	49	11	.	.	.
cord-341527-03rh966o	50	1	The	the	DT
cord-341527-03rh966o	50	2	mechanism	mechanism	NN
cord-341527-03rh966o	50	3	of	of	IN
cord-341527-03rh966o	50	4	hypoxemia	hypoxemia	NN
cord-341527-03rh966o	50	5	in	in	IN
cord-341527-03rh966o	50	6	COVID-19	COVID-19	NNP
cord-341527-03rh966o	50	7	is	be	VBZ
cord-341527-03rh966o	50	8	thought	think	VBN
cord-341527-03rh966o	50	9	to	to	TO
cord-341527-03rh966o	50	10	be	be	VB
cord-341527-03rh966o	50	11	disrupted	disrupt	VBN
cord-341527-03rh966o	50	12	pulmonary	pulmonary	JJ
cord-341527-03rh966o	50	13	vasoregulation	vasoregulation	NN
cord-341527-03rh966o	50	14	due	due	IN
cord-341527-03rh966o	50	15	to	to	IN
cord-341527-03rh966o	50	16	viral	viral	JJ
cord-341527-03rh966o	50	17	induced	induce	VBN
cord-341527-03rh966o	50	18	endothelial	endothelial	JJ
cord-341527-03rh966o	50	19	damage	damage	NN
cord-341527-03rh966o	50	20	of	of	IN
cord-341527-03rh966o	50	21	pulmonary	pulmonary	JJ
cord-341527-03rh966o	50	22	capillaries	capillary	NNS
cord-341527-03rh966o	50	23	and	and	CC
cord-341527-03rh966o	50	24	ensuing	ensue	VBG
cord-341527-03rh966o	50	25	V	v	NN
cord-341527-03rh966o	50	26	/	/	SYM
cord-341527-03rh966o	50	27	Q	q	NN
cord-341527-03rh966o	50	28	mismatch	mismatch	NN
cord-341527-03rh966o	50	29	[	[	-LRB-
cord-341527-03rh966o	50	30	6	6	CD
cord-341527-03rh966o	50	31	]	]	-RRB-
cord-341527-03rh966o	50	32	.	.	.
cord-341527-03rh966o	51	1	Recent	recent	JJ
cord-341527-03rh966o	51	2	studies	study	NNS
cord-341527-03rh966o	51	3	suggest	suggest	VBP
cord-341527-03rh966o	51	4	dexmedetomidine	dexmedetomidine	NNP
cord-341527-03rh966o	51	5	may	may	MD
cord-341527-03rh966o	51	6	enhance	enhance	VB
cord-341527-03rh966o	51	7	hypoxic	hypoxic	JJ
cord-341527-03rh966o	51	8	pulmonary	pulmonary	JJ
cord-341527-03rh966o	51	9	vasoconstriction	vasoconstriction	NN
cord-341527-03rh966o	51	10	,	,	,
cord-341527-03rh966o	51	11	improve	improve	VB
cord-341527-03rh966o	51	12	ventilation	ventilation	NN
cord-341527-03rh966o	51	13	/	/	SYM
cord-341527-03rh966o	51	14	perfusion	perfusion	NN
cord-341527-03rh966o	51	15	ratio	ratio	NN
cord-341527-03rh966o	51	16	and	and	CC
cord-341527-03rh966o	51	17	consequently	consequently	RB
cord-341527-03rh966o	51	18	improve	improve	VB
cord-341527-03rh966o	51	19	oxygenation	oxygenation	NN
cord-341527-03rh966o	51	20	[	[	-LRB-
cord-341527-03rh966o	51	21	7	7	CD
cord-341527-03rh966o	51	22	]	]	-RRB-
cord-341527-03rh966o	51	23	.	.	.
cord-341527-03rh966o	52	1	The	the	DT
cord-341527-03rh966o	52	2	uncertainty	uncertainty	NN
cord-341527-03rh966o	52	3	of	of	IN
cord-341527-03rh966o	52	4	COVID-19	COVID-19	NNP
cord-341527-03rh966o	52	5	has	have	VBZ
cord-341527-03rh966o	52	6	led	lead	VBN
cord-341527-03rh966o	52	7	to	to	IN
cord-341527-03rh966o	52	8	varying	vary	VBG
cord-341527-03rh966o	52	9	approaches	approach	NNS
cord-341527-03rh966o	52	10	in	in	IN
cord-341527-03rh966o	52	11	treatment	treatment	NN
cord-341527-03rh966o	52	12	which	which	WDT
cord-341527-03rh966o	52	13	have	have	VBP
cord-341527-03rh966o	52	14	yet	yet	RB
cord-341527-03rh966o	52	15	to	to	TO
cord-341527-03rh966o	52	16	be	be	VB
cord-341527-03rh966o	52	17	validated	validate	VBN
cord-341527-03rh966o	52	18	and	and	CC
cord-341527-03rh966o	52	19	are	be	VBP
cord-341527-03rh966o	52	20	not	not	RB
cord-341527-03rh966o	52	21	without	without	IN
cord-341527-03rh966o	52	22	their	-PRON-	PRP$
cord-341527-03rh966o	52	23	own	own	JJ
cord-341527-03rh966o	52	24	risks	risk	NNS
cord-341527-03rh966o	52	25	4	4	CD
cord-341527-03rh966o	52	26	.	.	.
cord-341527-03rh966o	53	1	In	in	IN
cord-341527-03rh966o	53	2	this	this	DT
cord-341527-03rh966o	53	3	case	case	NN
cord-341527-03rh966o	53	4	,	,	,
cord-341527-03rh966o	53	5	we	-PRON-	PRP
cord-341527-03rh966o	53	6	believe	believe	VBP
cord-341527-03rh966o	53	7	dexmedetomidine	dexmedetomidine	NNP
cord-341527-03rh966o	53	8	helped	help	VBD
cord-341527-03rh966o	53	9	one	one	CD
cord-341527-03rh966o	53	10	patient	patient	JJ
cord-341527-03rh966o	53	11	avoid	avoid	VB
cord-341527-03rh966o	53	12	mechanical	mechanical	JJ
cord-341527-03rh966o	53	13	ventilation	ventilation	NN
cord-341527-03rh966o	53	14	by	by	IN
cord-341527-03rh966o	53	15	improving	improve	VBG
cord-341527-03rh966o	53	16	compliance	compliance	NN
cord-341527-03rh966o	53	17	with	with	IN
cord-341527-03rh966o	53	18	non	non	JJ
cord-341527-03rh966o	53	19	-	-	JJ
cord-341527-03rh966o	53	20	invasive	invasive	JJ
cord-341527-03rh966o	53	21	ventilation	ventilation	NN
cord-341527-03rh966o	53	22	and	and	CC
cord-341527-03rh966o	53	23	promoting	promote	VBG
cord-341527-03rh966o	53	24	better	well	JJR
cord-341527-03rh966o	53	25	oxygenation	oxygenation	NN
cord-341527-03rh966o	53	26	.	.	.
cord-341527-03rh966o	54	1	Whether	whether	IN
cord-341527-03rh966o	54	2	that	that	DT
cord-341527-03rh966o	54	3	was	be	VBD
cord-341527-03rh966o	54	4	primarily	primarily	RB
cord-341527-03rh966o	54	5	due	due	JJ
cord-341527-03rh966o	54	6	to	to	IN
cord-341527-03rh966o	54	7	behavioral	behavioral	JJ
cord-341527-03rh966o	54	8	or	or	CC
cord-341527-03rh966o	54	9	physiologic	physiologic	JJ
cord-341527-03rh966o	54	10	changes	change	NNS
cord-341527-03rh966o	54	11	induced	induce	VBN
cord-341527-03rh966o	54	12	by	by	IN
cord-341527-03rh966o	54	13	the	the	DT
cord-341527-03rh966o	54	14	drug	drug	NN
cord-341527-03rh966o	54	15	is	be	VBZ
cord-341527-03rh966o	54	16	unknown	unknown	JJ
cord-341527-03rh966o	54	17	.	.	.
cord-341527-03rh966o	55	1	However	however	RB
cord-341527-03rh966o	55	2	,	,	,
cord-341527-03rh966o	55	3	this	this	DT
cord-341527-03rh966o	55	4	case	case	NN
cord-341527-03rh966o	55	5	suggests	suggest	VBZ
cord-341527-03rh966o	55	6	that	that	IN
cord-341527-03rh966o	55	7	the	the	DT
cord-341527-03rh966o	55	8	unique	unique	JJ
cord-341527-03rh966o	55	9	pharmacologic	pharmacologic	JJ
cord-341527-03rh966o	55	10	properties	property	NNS
cord-341527-03rh966o	55	11	of	of	IN
cord-341527-03rh966o	55	12	dexmedetomidine	dexmedetomidine	NN
cord-341527-03rh966o	55	13	may	may	MD
cord-341527-03rh966o	55	14	help	help	VB
cord-341527-03rh966o	55	15	decrease	decrease	VB
cord-341527-03rh966o	55	16	the	the	DT
cord-341527-03rh966o	55	17	need	need	NN
cord-341527-03rh966o	55	18	for	for	IN
cord-341527-03rh966o	55	19	mechanical	mechanical	JJ
cord-341527-03rh966o	55	20	ventilation	ventilation	NN
cord-341527-03rh966o	55	21	,	,	,
cord-341527-03rh966o	55	22	thereby	thereby	RB
cord-341527-03rh966o	55	23	reducing	reduce	VBG
cord-341527-03rh966o	55	24	mortality	mortality	NN
cord-341527-03rh966o	55	25	.	.	.
cord-341527-03rh966o	56	1	In	in	IN
cord-341527-03rh966o	56	2	the	the	DT
cord-341527-03rh966o	56	3	face	face	NN
cord-341527-03rh966o	56	4	of	of	IN
cord-341527-03rh966o	56	5	this	this	DT
cord-341527-03rh966o	56	6	novel	novel	JJ
cord-341527-03rh966o	56	7	and	and	CC
cord-341527-03rh966o	56	8	complicated	complicated	JJ
cord-341527-03rh966o	56	9	disease	disease	NN
cord-341527-03rh966o	56	10	,	,	,
cord-341527-03rh966o	56	11	the	the	DT
cord-341527-03rh966o	56	12	suggestion	suggestion	NN
cord-341527-03rh966o	56	13	of	of	IN
cord-341527-03rh966o	56	14	such	such	JJ
cord-341527-03rh966o	56	15	benefit	benefit	NN
cord-341527-03rh966o	56	16	is	be	VBZ
cord-341527-03rh966o	56	17	deserving	deserving	JJ
cord-341527-03rh966o	56	18	of	of	IN
cord-341527-03rh966o	56	19	further	further	JJ
cord-341527-03rh966o	56	20	investigation	investigation	NN
cord-341527-03rh966o	56	21	.	.	.
cord-341527-03rh966o	57	1	2	2	LS
cord-341527-03rh966o	58	1	Informed	inform	VBN
cord-341527-03rh966o	58	2	by	by	IN
cord-341527-03rh966o	58	3	recent	recent	JJ
cord-341527-03rh966o	58	4	experience	experience	NN
cord-341527-03rh966o	58	5	during	during	IN
cord-341527-03rh966o	58	6	the	the	DT
cord-341527-03rh966o	58	7	pandemic	pandemic	NN
cord-341527-03rh966o	58	8	.	.	.
cord-341527-03rh966o	59	1	3	3	CD
cord-341527-03rh966o	59	2	Average	average	JJ
cord-341527-03rh966o	59	3	saturations	saturation	NNS
cord-341527-03rh966o	59	4	after	after	IN
cord-341527-03rh966o	59	5	dexmedetomidine	dexmedetomidine	NNP
cord-341527-03rh966o	59	6	were	be	VBD
cord-341527-03rh966o	59	7	93	93	CD
cord-341527-03rh966o	59	8	%	%	NN
cord-341527-03rh966o	59	9	compared	compare	VBN
cord-341527-03rh966o	59	10	to	to	IN
cord-341527-03rh966o	59	11	92	92	CD
cord-341527-03rh966o	59	12	%	%	NN
cord-341527-03rh966o	59	13	prior	prior	RB
cord-341527-03rh966o	59	14	.	.	.
cord-341527-03rh966o	60	1	During	during	IN
cord-341527-03rh966o	60	2	this	this	DT
cord-341527-03rh966o	60	3	time	time	NN
cord-341527-03rh966o	60	4	,	,	,
cord-341527-03rh966o	60	5	occasional	occasional	JJ
cord-341527-03rh966o	60	6	increases	increase	NNS
cord-341527-03rh966o	60	7	in	in	IN
cord-341527-03rh966o	60	8	agitation	agitation	NN
cord-341527-03rh966o	60	9	(	(	-LRB-
cord-341527-03rh966o	60	10	correlated	correlate	VBN
cord-341527-03rh966o	60	11	with	with	IN
cord-341527-03rh966o	60	12	events	event	NNS
cord-341527-03rh966o	60	13	such	such	JJ
cord-341527-03rh966o	60	14	as	as	IN
cord-341527-03rh966o	60	15	bowel	bowel	NN
cord-341527-03rh966o	60	16	movements	movement	NNS
cord-341527-03rh966o	60	17	)	)	-RRB-
cord-341527-03rh966o	60	18	were	be	VBD
cord-341527-03rh966o	60	19	accompanied	accompany	VBN
cord-341527-03rh966o	60	20	by	by	IN
cord-341527-03rh966o	60	21	decreases	decrease	NNS
cord-341527-03rh966o	60	22	in	in	IN
cord-341527-03rh966o	60	23	saturation	saturation	NN
cord-341527-03rh966o	60	24	,	,	,
cord-341527-03rh966o	60	25	likely	likely	RB
cord-341527-03rh966o	60	26	lowering	lower	VBG
cord-341527-03rh966o	60	27	the	the	DT
cord-341527-03rh966o	60	28	overall	overall	JJ
cord-341527-03rh966o	60	29	average	average	NN
cord-341527-03rh966o	60	30	.	.	.
cord-341527-03rh966o	61	1	4	4	LS
cord-341527-03rh966o	62	1	Delaying	delay	VBG
cord-341527-03rh966o	62	2	intubation	intubation	NN
cord-341527-03rh966o	62	3	,	,	,
cord-341527-03rh966o	62	4	for	for	IN
cord-341527-03rh966o	62	5	example	example	NN
cord-341527-03rh966o	62	6	,	,	,
cord-341527-03rh966o	62	7	risks	risk	VBZ
cord-341527-03rh966o	62	8	suboptimal	suboptimal	JJ
cord-341527-03rh966o	62	9	intubation	intubation	NN
cord-341527-03rh966o	62	10	conditions	condition	NNS
cord-341527-03rh966o	62	11	should	should	MD
cord-341527-03rh966o	62	12	the	the	DT
cord-341527-03rh966o	62	13	patient	patient	NN
cord-341527-03rh966o	62	14	continue	continue	VB
cord-341527-03rh966o	62	15	to	to	TO
cord-341527-03rh966o	62	16	progress	progress	VB
cord-341527-03rh966o	62	17	in	in	IN
cord-341527-03rh966o	62	18	their	-PRON-	PRP$
cord-341527-03rh966o	62	19	disease	disease	NN
cord-341527-03rh966o	62	20	,	,	,
cord-341527-03rh966o	62	21	and	and	CC
cord-341527-03rh966o	62	22	certainly	certainly	RB
cord-341527-03rh966o	62	23	requires	require	VBZ
cord-341527-03rh966o	62	24	heightened	heightened	JJ
cord-341527-03rh966o	62	25	vigilance	vigilance	NN
cord-341527-03rh966o	62	26	while	while	IN
cord-341527-03rh966o	62	27	a	a	DT
cord-341527-03rh966o	62	28	patient	patient	NN
cord-341527-03rh966o	62	29	remains	remain	VBZ
cord-341527-03rh966o	62	30	on	on	IN
cord-341527-03rh966o	62	31	life	life	NN
cord-341527-03rh966o	62	32	sustaining	sustain	VBG
cord-341527-03rh966o	62	33	non	non	JJ
cord-341527-03rh966o	62	34	-	-	JJ
cord-341527-03rh966o	62	35	invasive	invasive	JJ
cord-341527-03rh966o	62	36	ventilation	ventilation	NN
cord-341527-03rh966o	62	37	.	.	.
cord-341527-03rh966o	63	1	Cases	case	NNS
cord-341527-03rh966o	63	2	in	in	IN
cord-341527-03rh966o	63	3	the	the	DT
cord-341527-03rh966o	63	4	US	US	NNP
cord-341527-03rh966o	63	5	Presenting	Presenting	NNP
cord-341527-03rh966o	63	6	Characteristics	Characteristics	NNP
cord-341527-03rh966o	63	7	,	,	,
cord-341527-03rh966o	63	8	Comorbidities	Comorbidities	NNPS
cord-341527-03rh966o	63	9	,	,	,
cord-341527-03rh966o	63	10	and	and	CC
cord-341527-03rh966o	63	11	Outcomes	outcome	NNS
cord-341527-03rh966o	64	1	Among	among	IN
cord-341527-03rh966o	64	2	5700	5700	CD
cord-341527-03rh966o	64	3	Patients	patient	NNS
cord-341527-03rh966o	64	4	Hospitalized	hospitalize	VBN
cord-341527-03rh966o	64	5	With	with	IN
cord-341527-03rh966o	64	6	COVID-19	COVID-19	NNP
cord-341527-03rh966o	64	7	in	in	IN
cord-341527-03rh966o	64	8	the	the	DT
cord-341527-03rh966o	64	9	New	New	NNP
cord-341527-03rh966o	64	10	York	York	NNP
cord-341527-03rh966o	64	11	City	City	NNP
cord-341527-03rh966o	64	12	Area	Area	NNP
cord-341527-03rh966o	64	13	19	19	CD
cord-341527-03rh966o	64	14	Treatment	Treatment	NNP
cord-341527-03rh966o	64	15	Guidelines	Guidelines	NNPS
cord-341527-03rh966o	64	16	.	.	.
cord-341527-03rh966o	65	1	Care	care	NN
cord-341527-03rh966o	65	2	of	of	IN
cord-341527-03rh966o	65	3	Critically	Critically	NNP
cord-341527-03rh966o	65	4	Ill	Ill	NNP
cord-341527-03rh966o	65	5	Patients	Patients	NNPS
cord-341527-03rh966o	65	6	with	with	IN
cord-341527-03rh966o	65	7	COVID-19	COVID-19	NNP
cord-341527-03rh966o	65	8	Alpha-2	Alpha-2	NNP
cord-341527-03rh966o	65	9	adrenergic	adrenergic	JJ
cord-341527-03rh966o	65	10	receptor	receptor	NN
cord-341527-03rh966o	65	11	agonists	agonist	NNS
cord-341527-03rh966o	65	12	:	:	:
cord-341527-03rh966o	65	13	a	a	DT
cord-341527-03rh966o	65	14	review	review	NN
cord-341527-03rh966o	65	15	of	of	IN
cord-341527-03rh966o	65	16	current	current	JJ
cord-341527-03rh966o	65	17	clinical	clinical	JJ
cord-341527-03rh966o	65	18	applications	application	NNS
cord-341527-03rh966o	66	1	The	the	DT
cord-341527-03rh966o	66	2	effect	effect	NN
cord-341527-03rh966o	66	3	of	of	IN
cord-341527-03rh966o	66	4	dexmedetomidine	dexmedetomidine	NN
cord-341527-03rh966o	66	5	on	on	IN
cord-341527-03rh966o	66	6	delirium	delirium	NN
cord-341527-03rh966o	66	7	and	and	CC
cord-341527-03rh966o	66	8	agitation	agitation	NN
cord-341527-03rh966o	66	9	in	in	IN
cord-341527-03rh966o	66	10	patients	patient	NNS
cord-341527-03rh966o	66	11	in	in	IN
cord-341527-03rh966o	66	12	intensive	intensive	JJ
cord-341527-03rh966o	66	13	care	care	NN
cord-341527-03rh966o	66	14	:	:	:
cord-341527-03rh966o	66	15	systematic	systematic	JJ
cord-341527-03rh966o	66	16	review	review	NN
cord-341527-03rh966o	66	17	and	and	CC
cord-341527-03rh966o	66	18	meta	meta	NNP
cord-341527-03rh966o	66	19	-	-	HYPH
cord-341527-03rh966o	66	20	analysis	analysis	NN
cord-341527-03rh966o	66	21	with	with	IN
cord-341527-03rh966o	66	22	trial	trial	NN
cord-341527-03rh966o	66	23	sequential	sequential	JJ
cord-341527-03rh966o	66	24	analysis	analysis	NN
cord-341527-03rh966o	66	25	Management	Management	NNP
cord-341527-03rh966o	66	26	of	of	IN
cord-341527-03rh966o	66	27	COVID-19	COVID-19	NNP
cord-341527-03rh966o	66	28	Respiratory	Respiratory	NNP
cord-341527-03rh966o	66	29	Distress	Distress	NNP
cord-341527-03rh966o	66	30	Evaluation	Evaluation	NNP
cord-341527-03rh966o	66	31	of	of	IN
cord-341527-03rh966o	66	32	the	the	DT
cord-341527-03rh966o	66	33	effects	effect	NNS
cord-341527-03rh966o	66	34	of	of	IN
cord-341527-03rh966o	66	35	dexmedetomidine	dexmedetomidine	JJ
cord-341527-03rh966o	66	36	infusion	infusion	NN
cord-341527-03rh966o	66	37	on	on	IN
cord-341527-03rh966o	66	38	oxygenation	oxygenation	NN
cord-341527-03rh966o	66	39	and	and	CC
cord-341527-03rh966o	66	40	lung	lung	NN
cord-341527-03rh966o	66	41	mechanics	mechanic	NNS
cord-341527-03rh966o	66	42	in	in	IN
cord-341527-03rh966o	66	43	morbidly	morbidly	RB
cord-341527-03rh966o	66	44	obese	obese	JJ
cord-341527-03rh966o	66	45	patients	patient	NNS
cord-341527-03rh966o	66	46	with	with	IN
cord-341527-03rh966o	66	47	restrictive	restrictive	JJ
cord-341527-03rh966o	66	48	lung	lung	NN
cord-341527-03rh966o	66	49	disease	disease	NN