id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-349561-4mkiwg9k	Porta, Alessandra Della	Acute chloroquine and hydroxychloroquine toxicity: A review for emergency clinicians	2020-07-19		.txt	text/plain	9231	598	44	BACKGROUND: Acute chloroquine and hydroxychloroquine toxicity is characterized by a combination of direct cardiovascular effects and electrolyte derangements with resultant dysrhythmias and is associated with significant morbidity and mortality. Following the United States Food and Drug Administration emergency use authorization for chloroquine and hydroxychloroquine in the treatment of SARS-CoV-2, many additional clinical trials with randomization, blinding, and larger sample sizes were initiated to determine the benefit and risks. 59 While unlikely to occur in acute overdose, cardiomyopathy is described in case reports of patients presenting with chronic chloroquine and/or hydroxychloroquine toxicity. 59 While unlikely to occur in acute overdose, cardiomyopathy is described in case reports of patients presenting with chronic chloroquine and/or hydroxychloroquine toxicity. Although case report literature describes the finding in chloroquine and hydroxychloroquine use, the largest chart review to date examining these drugs in patients with G6PD noted no occurrence of hemolysis.	./cache/cord-349561-4mkiwg9k.txt	./txt/cord-349561-4mkiwg9k.txt