id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-344154-j5jjl0ok	Kandil, Manar	MAGraine: Magnesium compared to conventional therapy for treatment of migraines	2020-09-14		.txt	text/plain	2551	147	51	This study was a single-center, prospective, double-blinded, randomized-controlled, three-armed trial comparing magnesium, metoclopramide, and prochlorperazine for the treatment of migraine. 15 Secondary endpoints included change in pain score from baseline to 60 minutes and 120 minutes after initiation of infusion (as defined on a 11-point NRS), ED length of stay, and J o u r n a l P r e -p r o o f Journal Pre-proof necessity for rescue analgesia at any time following the study drug administration. No statistically significant differences in change in pain scores were found between all three treatment arms; however, a post hoc noninferiority analysis revealed that when compared to prochlorperazine and metoclopramide, IV magnesium was non-inferior ( figure 3) . The results of the MAGraine study demonstrated that IV magnesium sulfate, metoclopramide, and prochlorperazine were effective in decreasing pain scores for migraines at 30, 60, and 120 minutes, however one agent was not superior to the rest.	./cache/cord-344154-j5jjl0ok.txt	./txt/cord-344154-j5jjl0ok.txt