id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-012818-zr4xw3ph	Zhang, Ying-ying	A comparative pharmacogenomic analysis of three classic TCM prescriptions for coronary heart disease based on molecular network modeling	2020-02-12		.txt	text/plain	6283	301	32	These organized pharmacological disturbance was mainly focused on almost all stages of CHD intervention, such as anti-atherosclerosis, lipid metabolism, inflammation, vascular wall function, foam cells formation, platelets aggregation, thrombosis, arrhythmia, and ischemia-reperfusion injury. The calcium signaling pathway is a hub induction switch in CHD that is involved in the inflammatory process of atherogenesis [25] and affects coronary endothelial function [26] , foam cell formation [27] , vascular tension adjustment [28] , platelet aggregation [29] , and vascular smooth muscle cell (VSMC) and fibroblast proliferation [30, 31] . Compared with patients without coronary artery disease (CAD), CAD patients have significantly decreased bile acid excretion levels, which may be a risk factor in the process of atherosclerosis [43] ; in addition, bile acid may modulate endothelial function as vascular endothelial cells express the G protein-coupled bile acid receptor [44] .	./cache/cord-012818-zr4xw3ph.txt	./txt/cord-012818-zr4xw3ph.txt