Ongy654.qxd © 2003 S. Karger AG, Basel Fax + 41 61 306 12 34 Access to full text and tables of contents, E-Mail karger@karger.ch including tentative ones for forthcoming issues: www.karger.com www.karger.com/ocl_issues Contents Vol. 65, 2003 No. 1 Review 1 How to Interpret Serum CA 125 Levels in Patients with Serosal Involvement? A Clinical Dilemma Sevinc, A.; Camci, C.; Turk, H.M.; Buyukberber, S. (Gaziantep) Clinical Studies 7 Alveolar Soft Part Sarcoma in Japan: Multi-Institutional Study of 57 Patients from the Japanese Musculoskeletal Oncology Group Ogose, A. (Niigata); Yazawa, Y. (Utsunomiya); Ueda, T. (Osaka); Hotta, T.; Kawashima, H.; Hatano, H.; Morita, T. (Niigata) 14 Impact of Overall Treatment Time on Local Control of Anal Cancer Treated with Radiochemotherapy Graf, R.; Wust, P.; Hildebrandt, B.; Gögler, H.; Ullrich, R. (Berlin); Herrmann, R. (Basel); Riess, H.; Felix, R. (Berlin) 23 Pain after Quadrantectomy and Radiotherapy for Early-Stage Breast Cancer: Incidence, Characteristics and Influence on Quality of Life. Results from a Retrospective Study Amichetti, M.; Caffo, O. (Trento) 29 Long-Term Prognosis of Stage I Ovarian Carcinoma. Prognostic Importance of Intraoperative Rupture Mizuno, M.; Kikkawa, F.; Shibata, K.; Kajiyama, H.; Suzuki, T.; Ino, K. (Nagoya); Kawai, M. (Toyohashi); Mizutani, S. (Nagoya) Laboratory/Clinical Translational Research 37 Increased Expression of RelA/Nuclear Factor-��B Protein Correlates with Colorectal Tumorigenesis Yu, H.-G. (Wuhan/Bochum); Yu, L.-L.; Yang, Y.; Luo, H.-S.; Yu, J.-P. (Wuhan); Meier, J.J.; Schrader, H.; Bastian, A.; Schmidt, W.E.; Schmitz, F. (Bochum) 46 A Novel Case of a CAT to AAT Transversion in Codon 179 of the p53 Gene in a Supratentorial Primitive Neuroectodermal Tumor Harbored by a Young Girl. Case Report and Review of the Literature Postovsky, S.; Weyl Ben Arush, M.; Elhasid, R.; Davidson, S.; Leshanski, L.; Vlodavsky, E.; Guilburd, J.N. (Haifa); Amikam, D. (Haifa/Tel-Hai) 52 Prognostic Role of Serum Sialyl Lewisx (CD15s) in Colorectal Cancer Paganuzzi, M.; Bobbio, B.; Marroni, P.; Filiberti, R.; Secco, G.B.; Grossi, C.E. (Genoa) 60 Molecular Biologic Characteristics of Seven New Cell Lines of Squamous Cell Carcinomas of the Head and Neck and Comparison to Fresh Tumor Tissue Welkoborsky, H.-J. (Hannover); Jacob, R.; Riazimand, S.H.; Bernauer, H.S.; Mann, W.J. (Mainz) 72 Expression of c-met Tyrosine Kinase Receptor Is Biologically and Prognostically Relevant for Primary Cutaneous Malignant Melanomas Cruz, J. (Porto); Reis-Filho, J.S. (Porto/Braga); Silva, P.; Lopes, J.M. (Porto) 83 Fas Ligand Expression Is Correlated with Metastasis in Colorectal Carcinoma Nozoe, T.; Yasuda, M.; Honda, M.; Inutsuka, S.; Korenaga, D. (Fukuoka) 89 Abnormal Fragile Histidine Triad Expression in Advanced Cervical Cancer and Evaluation of Its Utility as a Prognostic Factor Machida, S.; Ohwada, M.; Saga, Y.; Suzuki, M. (Tochigi) 94 Book Review No. 2 Clinical Studies 95 AFP-Producing Gastric Carcinoma: Multivariate Analysis of Prognostic Factors in 270 Patients Adachi, Y. (Oita); Tsuchihashi, J. (Fukuoka); Shiraishi, N.; Yasuda, K.; Etoh, T.; Kitano, S. (Oita) 102 Phase I Study of Combination Chemotherapy Using Irinotecan Hydrochloride and Nedaplatin for Advanced or Recurrent Cervical Cancer Machida, S.; Ohwada, M. (Tochigi); Fujiwara, H.; Konno, R.; Takano, M.; Kita, T.; Kikuchi, Y.; Komiyama, S.; Mikami, M. (Saitama); Suzuki, M. (Tochigi) 108 High Incidence of Angina pectoris in Patients Treated with 5-Fluorouracil. A Planned Surveillance Study with 102 Patients Wacker, A.; Lersch, C.; Scherpinski, U.; Reindl, L.; Seyfarth, M. (München) 113 Features of Second Primary Cancer in Patients with Gastric Cancer Ikeda, Y.; Saku, M.; Kawanaka, H.; Nonaka, M.; Yoshida, K. (Fukuoka) 118 Central Nervous System Involvement in Children with Sarcoma Postovsky, S. (Haifa); Ash, S. (Petach Tikva); Ramu, I.N. (Jerusalem); Yaniv, Y.; Zaizov, R. (Petach Tikva); Futerman, B. (Haifa); Elhasid, R.; BenBarak, A.; Halil, A.; Ben Arush, M.W. (Haifa) Laboratory/Clinical Translational Research 125 Quantitative Analysis of Thymidine Phosphorylase and Dihydropyrimidine Dehydrogenase in Renal Cell Carcinoma Morita, T.; Matsuzaki, A.; Tokue, A. (Tochigi) 132 Association between Serum Carcinoembryonic Antigen and Endothelial Cell Adhesion Molecules in Colorectal Cancer Roselli, M.; Guadagni, F.; Martini, F.; Spila, A.; Mariotti, S.; D’Alessandro, R.; Aloe, S.; Gazzaniga, P.P.; Basili, S.; Cosimelli, M.; Ferroni, P. (Rome) 139 Clinical Relevance of Sialyltransferases ST6GAL-I and ST3GAL-III in Gastric Cancer Gretschel, S.; Haensch, W.; Schlag, P.M.; Kemmner, W. (Berlin) 146 Colorectal Cancer Relapse: Allelic Alterations Associated with Tumour Marker Overexpression Vegh, I.; De-La-Cruz, J.; Navarro, S.; Morales, C.; Colina, F.; Abad, A.; De-La-Calle, A.; Enriquez-de-Salamanca, R.; Moreno-González, E. (Madrid) 152 Expression of Phosphatidylethanolamine N-Methyltransferase in Human Hepatocellular Carcinomas Tessitore, L. (Novara); Marengo, B. (Genoa); Vance, D.E. (Edmonton, Alta.); Papotti, M.; Mussa, A. (Turin); Daidone, M.G.; Costa, A. (Milan) 159 Alteration of G2 Cell Cycle Regulators Occurs during Carcinogenesis of the Endometrium Tsuda, H.; Hashiguchi, Y.; Inoue, T.; Yamamoto, K. (Osaka) Contents Oncology Vol. 65, 2003 III Laboratory Investigations 167 Interleukin-1�� Enhances Integrin ��6��1 Expression and Metastatic Capability of Human Pancreatic Cancer Sawai, H.; Funahashi, H.; Yamamoto, M.; Okada, Y.; Hayakawa, T.; Tanaka, M.; Takeyama, H.; Manabe, T. (Nagoya) 174 Adhesion and Migration of HRT-18 Colorectal Carcinoma Cells on Extracellular Matrix Components Typical for the Desmoplastic Stroma of Colorectal Adenocarcinomas Hauptmann, S. (Berlin); Budianto, D. (Aachen); Denkert, C.; Köbel, M. (Berlin); Borsi, L.; Siri, A. (Genova) Case Report 182 Successful Treatment of Human Immunodeficiency Virus-Related Castleman’s Disease: A Case Report and Literature Review Liberopoulos, E.; Tolis, C.; Bai, M.; Efremidis, S.; Pavlidis, N.; Elisaf, M. (Ioannina) 112 Erratum No. 3 Invited Review 187 Gastrointestinal Stromal Tumors: Biology and Treatment Duffaud, F. (Marseille); Blay, J.-Y. (Lyon) Clinical Studies 198 Elderly Patients with Advanced Non-Small Cell Lung Cancer. A Phase II Study with Weekly Cisplatin and Gemcitabine Berardi, R.; Porfiri, E.; Scartozzi, M.; Lippe, P. (Ancona); Silva, R.R. (Fabriano); Nacciarriti, D.; Menichetti, E.T. (Senigallia); Tummarello, D.; Carle, F.; Piga, A.; Cellerino, R. (Ancona) 204 Recurrence Rate and Prognosis of Patients with Hepatocellular Carcinoma That Developed after Elimination of Hepatitis C Virus RNA by Interferon Therapy. A Closed Cohort Study Including Matched Control Patients Ikeda, K.; Kobayashi, M.; Saitoh, S.; Someya, T.; Hosaka, T.; Akuta, N.; Suzuki, F.; Tsubota, A.; Suzuki, Y.; Arase, Y.; Kumada, H. (Tokyo) 211 Effective Combination Chemotherapy with Bimonthly Docetaxel and Cisplatin with or without Hematopoietic Growth Factor Support in Patients with Advanced Gastroesophageal Cancer Schüll, B.; Kornek, G.V.; Schmid, K.; Raderer, M.; Hejna, M.; Lenauer, A.; Depisch, D. (Vienna); Lang, F. (Neunkirchen); Scheithauer, W. (Vienna) 218 Phase II Study of Gemcitabine plus Docetaxel in Advanced Pancreatic Cancer: A Hoosier Oncology Group Study Schneider, B.P.; Ganjoo, K.N.; Seitz, D.E. (Indianapolis, Ind.); Picus, J. (St. Louis, Mo.); Fata, F. (Goshen, Ind.); Stoner, C.; Calley, C.; Loehrer, P.J. (Indianapolis, Ind.) 224 Phase II Trial of Weekly Paclitaxel in Previously Untreated Advanced Non-Small-Cell Lung Cancer Yasuda, K.; Igishi, T.; Kawasaki, Y.; Yamamoto, M.; Kato, K.; Matsumoto, S.; Kotani, M.; Sako, T.; Shigeoka, Y.; Sugitani, A.; Histuda, Y.; Shimizu, E. (Yonago) 229 Changes in the Activation and Reconstitution of Lymphocytes Resulting from Total-Body Irradiation Correlate with Slowed Tumor Growth Miller, G.M.; Kim, D.W.; Andres, M.L.; Green, L.M.; Gridley, D.S. (Loma Linda, Calif.) 242 Low-Dose Thalidomide Treatment for Advanced Hepatocellular Carcinoma Hsu, C.; Chen, C.-N. (Taipei); Chen, L.-T. (Taipei/Kaohsiung); Wu, C.-Y.; Yang, P.-M.; Lai, M.-Y.; Lee, P.-H.; Cheng, A.-L. (Taipei) 250 Prevention of Intrahepatic Metastasis by Curcumin in an Orthotopic Implantation Model Ohashi, Y.; Tsuchiya, Y.; Koizumi, K.; Sakurai, H.; Saiki, I. (Toyama) 259 Anaplastic Oligodendrogliomas: Prognostic Factors for Tumor Recurrence and Survival Puduvalli, V.K.; Hashmi, M. (Houston, Tex.); McAllister, L.D. (Portland, Oreg.); Levin, V.A.; Hess, K.R. (Houston, Tex.); Prados, M. (San Francisco, Calif.); Jaeckle, K.A.; Yung, W.K.A. (Houston, Tex.); Buys, S.S. (Salt Lake City, Utah); Bruner, J.M. (Houston, Tex.); Townsend, J.J. (Salt Lake City, Utah); Davis, R. (San Francisco, Calif.); Sawaya, R.; Kyritsis, A.P. (Houston, Tex.) Laboratory/Clinical Translational Research 267 Forced Expression of Cytidine Deaminase Confers Sensitivity to Capecitabine Morita, T.; Matsuzaki, A.; Kurokawa, S.; Tokue, A. (Tochigi) 275 Helicobactor pylori Infection Is Closely Associated with Telomere Reduction in Gastric Mucosa Kuniyasu, H. (Kashihara); Kitadai, Y.; Mieno, H.; Yasui, W. (Hiroshima) Letter to the Editor 283 Comparison of Low-Dose versus Standard-Dose Colony Stimulating Factor in Patients with Chemotherapy-Induced Febrile Neutropenia Burney, I.A.; Salam, A.; Jat, A.A.; Iqbal, M.P.; Siddiqui, T.; Khan, M.A.; Smego, R.A., Jr. (Karachi) No. 4 Clinical Studies 285 Multiple Signal Pathways Are Involved in the Mitogenic Effect of 5(S)-HETE in Human Pancreatic Cancer Ding, X.-Z.; Tong, W.-G.; Adrian, T.E. (Chicago, Ill.) 295 Usefulness of 99mTc-Tetrofosmin Scintigraphy in Different Variants of Kaposi’s Sarcoma Spanu, A.; Madeddu, Gr.; Cottoni, F.; Manca, A.; Migaleddu, V.; Chessa, F.; Masala, M.V.; Cossu, A.; Falchi, A.; Mura, M.S.; Madeddu, G. (Sassari) 306 Rituximab for Treatment of Advanced Extranodal Marginal Zone B Cell Lymphoma of the Mucosa-Associated Lymphoid Tissue Lymphoma Raderer, M. (Vienna); Jäger, G. (Graz); Brugger, S. (St. Pölten); Püspök, A.; Fiebiger, W.; Drach, J. (Vienna); Wotherspoon, A. (London); Chott, A. (Vienna) 311 Role of Mammography, Ultrasound and Large Core Biopsy in the Diagnostic Evaluation of Papillary Breast Lesions Puglisi, F.; Zuiani, C.; Bazzocchi, M.; Valent, F.; Aprile, G.; Pertoldi, B.; Minisini, A.M.; Cedolini, C.; Londero, V.; Piga, A.; Di Loreto, C. (Udine) 316 Impact of Interval Debulking Surgery of Clinical Outcome in Primary Unresectable FIGO Stage IIIc Ovarian Cancer Patients Fanfani, F.; Ferrandina, G.; Corrado, G.; Fagotti, A.; Zakut, H.V.; Mancuso, S.; Scambia, G. (Rome) Laboratory/Clinical Translational Research 323 Metal Contents in the Liver of Patients with Chronic Liver Disease Caused by Hepatitis C Virus. Reference to Hepatocellular Carcinoma Ebara, M.; Fukuda, H.; Hatano, R.; Yoshikawa, M.; Sugiura, N.; Saisho, H.; Kondo, F.; Yukawa, M. (Chiba) 331 Changes in Apoptosis and Mitotic Index, p53 and Ki67 Expression in Various Types of Oral Leukoplakia Kövesi, G.; Szende, B. (Budapest) 337 Low Collagenase-1 (MMP-1) and MT1-MMP Expression Levels Are Favourable Survival Markers in Advanced Colorectal Carcinoma Bendardaf, R.; Lamlum, H.; Vihinen, P.; Ristamäki, R.; Laine, J.; Pyrhönen, S. (Turku) 347 The Supplementary Diagnostic Power of Selected Immunohistochemical, Molecular Genetic and Infective Parameters in Epithelial Hyperplastic Laryngeal Lesions Kleist, B.; Junghans, D.; Lorenz, G.; Bankau, A.; Poetsch, M. (Greifswald) Contents Oncology Vol. 65, 2003IV S. Karger Medical and Scientific Publishers Basel � Freiburg � Paris � London New York � Bangalore � Bangkok Singapore � Tokyo � Sydney Drug Dosage The authors and the publisher have exerted every effort to en- sure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of informa- tion relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precau- tions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center (see ‘General Information’). © Copyright 2003 by S. Karger AG, P.O. Box, CH–4009 Basel (Switzerland) Printed in Switzerland on acid-free paper by Reinhardt Druck, Basel 355 Skp2 and Jab1 Expression Are Associated with Inverse Expression of p27KIP1 and Poor Prognosis in Oral Squamous Cell Carcinomas Shintani, S.; Li, C.; Mihara, M.; Hino, S.; Nakashiro, K.-i.; Hamakawa, H. (Ehime) 363 Seprase, a Membrane-Type Serine Protease, Has Different Expression Patterns in Intestinal- and Diffuse-Type Gastric Cancer Okada, K. (Yamanashi/Tokyo); Chen, W.-T. (Stony Brook, N.Y.); Iwasa, S.; Jin, X. (Tokyo); Yamane, T.; Ooi, A. (Yamanashi); Mitsumata, M. (Tokyo) 371 Loss of p27 Expression Is Associated with Poor Prognosis in Stage I–II Pancreatic Cancer Juuti, A.; Nordling, S.; Louhimo, J.; Lundin, J.; von Boguslawski, K.; Haglund, C. (Helsinki) Letter to the Editor 378 Taxol plus Gemcitabine and Vinorelbine Given Every Other Week in Advanced Chemo-Naïve Non-Small Cell Lung Cancer Patients Frasci, G.; Comella, P.; De Cataldis, G.; Maiorino, L.; Fiore, F.; De Rosa, V.; Lapenta, L.; Licenziato, M.; Comella, G. (Naples) 305 Announcement 380 Acknowledgement to the Reviewers 383 Author Index Vol. 65, 2003 385 Subject Index Vol. 65, 2003 Suppl. 1 New Aspects in the Diagnosis and Treatment of Prostate Cancer Guest Editors: K. Miller; T. Wiegel; W. Hinkelbein (Berlin) Suppl. 2 Ifosfamide: A Milestone Drug International Meeting, Padua, February 17–18, 2003 Guest Editor: G. Cartei (Padua)