id author title date pages extension mime words sentences flesch summary cache txt work_sq63trlpcbe63bn724trmfkrdi Fan Zhang Novel alternative splicing isoform biomarkers identification from high-throughput plasma proteomics profiling of breast cancer 2013 9 .pdf application/pdf 6016 688 43 Results: Therefore, we presented a peptidomics approach to searching novel alternative splicing isoforms in types of high-quality alternative splicing isoform biomarkers. characterize alternative splicing isoforms from MS-based proteomics experiments with more coverage and alternative splicing isoform biomarkers for early detection of cancer. In cancer, many examples of alternative splicing isoforms were reported [17-21]. Our peptidomics approach to identifying novel alternative splicing isoform in proteomics data includes three Figure 1 A peptidomics approach to identifying novel alternative splicing isoforms in proteomics data. searching novel alternative splicing isoform in the proteomics data (Table 1). eight alternative splicing isoforms are transcription factor, signaling, cancer, and synthesis (Table 2). novel alternative splicing isoform in proteomics data, use it to identify two types of common alternative splicing events: Exon Skipping and Intron Retention. Table 1 Novel alternative splicing isoform candidate biomarkers for breast cancer in plasma Peptidomics approach to searching novel alternative splicing isoform in proteomics data ./cache/work_sq63trlpcbe63bn724trmfkrdi.pdf ./txt/work_sq63trlpcbe63bn724trmfkrdi.txt