id author title date pages extension mime words sentences flesch summary cache txt work_dhc4twoqlfgcjmgmykvmojl4ue Vishal Vashistha Current and recent clinical trials for perioperative systemic therapy for muscle invasive bladder cancer: a systematic review 2014 15 .pdf application/pdf 12441 1160 53 remained limited to radical cystectomy with or without cisplatin-based neoadjuvant and/or adjuvant chemotherapy. We reviewed the current and recent clinical trials evaluating perioperative chemotherapy, targeted therapy, and Trials Registry and MEDLINE were further searched specifically for perioperative MIBC chemotherapy, targeted phase III trials of targeted therapy and other therapeutic approaches are necessary before the current cisplatin-based #This result includes phase III perioperative chemotherapy trials, phase II targeted therapy trials, and clinical trials of all phases for mTOR inhibitors, immune Table 2 Meta-analyses of perioperative chemotherapy phase III trials for MIBC Table 3 Current and recent perioperative chemotherapy phase III trials for MIBC Table 4 Current and recent perioperative targeted therapy phase II trials for MIBC study evaluating the efficacy and tolerability of a splitdosed cisplatin regimen for patients with renal impairment that was not found with the neoadjuvant chemotherapy trials systematic review [37-39]. ./cache/work_dhc4twoqlfgcjmgmykvmojl4ue.pdf ./txt/work_dhc4twoqlfgcjmgmykvmojl4ue.txt