id author title date pages extension mime words sentences flesch summary cache txt work_6edatbslnjhz3kb2pkbphqv5py M T Bandealy Prospective randomized trial of 5-fluorouracil versus 5-fluorouracil plus levamisole in the treatment of metastatic colorectal cancer: a Hoosier Oncology Group trial 1998 6 .pdf application/pdf 4998 522 68 response rate, duration of remission, and survival of 5-fluorouracil (5-FU) versus those of 5-FU plus levamisole in metastatic colorectal cancer using the same dose and schedule of these agents as in the North Central Cancer Treatment Group and intergroup studies of adjuvant therapy. Patients with no prior history of chemotherapy for metastatic disease were entered on this Hoosier Oncology Group the European Organization for Research and Treatment of Cancer compared levamisole to placebo in the adjuvant setting and Phase III studies of 5-FU plus levamisole in metastatic coborectal cancer. One hundred patients were randomized to 5-Hi plus levamisole, of whom 4 never received treatment and S had inadequate response data. grade 3/4 diarrhea in the 5-FU plus levamisole arm was statistically significant (P = 0.0146), whereas the difference in the reported a trial of 5-Hi versus 5-Hi plus levamisole in metastatic colorectal cancer in patients with nonmeasurabbe disease ./cache/work_6edatbslnjhz3kb2pkbphqv5py.pdf ./txt/work_6edatbslnjhz3kb2pkbphqv5py.txt