id author title date pages extension mime words sentences flesch summary cache txt work_qrsjz7lugrg6pohawdy5j5s7nq Judith Cebra-Thomas How the turtle forms its shell: a paracrine hypothesis of carapace formation 2005.0 12 .pdf application/pdf 7375 693 68 show here that the carapacial ridge (CR) is critical for the entry of the ribs into the dorsal dermis. precursor cells depend upon fibroblast growth factor (FGF) signaling. costal bones that develop in the dermis (immediately dorsal to the ribs) and extend to the marginal have not been extensively studied, turtle gastrulation and somite formation are similar to those of extirpation experiments on snapping turtles, confirming a somitic origin for the ribs and dermis of developing ribs secrete bone morphogenetic proteins (BMPs) that induce the costal bones that that BMPs produced during the normal endochondral ossification of the rib (Fig. 1C) induce the costal bones can be seen forming around the proximal portion of the ribs. Expression of fg8 and fgf10 as the ribs enter the turtle forms most of its costal bones after it has FGF10-coated beads, the ribs developed normally on the bone formation around the ribs. ./cache/work_qrsjz7lugrg6pohawdy5j5s7nq.pdf ./txt/work_qrsjz7lugrg6pohawdy5j5s7nq.txt