id author title date pages extension mime words sentences flesch summary cache txt work_4qabwxy7effildblswnw7mkrvi R. Collier Reducing the "pill burden" 2012.0 2 .pdf application/pdf 1009 62 57 "One way to get around the complexity issue is to make a drug regimen appeal of fixed-dose combination drugs which combine two or more drugs into were treated either with two medications or with a fixed-dose combination combination drugs for chronic illnesses. Fixed-dose combination products combination of existing drugs. drugs," says Messerli. "It's easier to combine drugs and make money that way." -component drugs. trial for fixed-dose drugs is based on individual component, however, drug safety data for each separate drug or guidance document (www.fda.gov accelerate the approval process if sufficient data exists for the component instance, for fixed-dose combinations or copackaged drug products made with individually approved HIV drugs, FDC [fixed-dose combination] or copackaged configuration of those drugs .fda .gov/downloads/Drugs/Guidance comply with fixed-dose combination dosing regimens," the document states. doses of combined medications if Still, the primary benefit of combination drugs — a substantial increase increasingly complex drug regimens." ./cache/work_4qabwxy7effildblswnw7mkrvi.pdf ./txt/work_4qabwxy7effildblswnw7mkrvi.txt