id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_ese5a35olbgtnazmyggs7tkx3u	Michael J. Pazzani	Application of an Expert System in the Management of HIV-Infected Patients	1997	7	.pdf	application/pdf	5908	853	70	Thus, the CTSHIV system couples efficient genetic sequencing with an expert program that recommends regimens based on information in the current medical literature. Rule-based expert systems (13,14) are computer programs that declaratively represent knowledge of a specialized problem and facts about a specific case? In the program developed for the current study (Customized Treatment Strategies for HIV [CTSHIV]), the rules encode information Complete set qf current rules qf the Customized Treatment Strategies for HIV expert program By rule I, AZT reduced by 0.12 because two sequences had TTG at codon 41 of the Resistance-related mutations in the HIV-1 protease gene of patients treated drug resistance during zidovudine therapy of HIV infection. Multiple mutations in HIV-l reverse transcriptase confer high-level resistance to zidovudine (AZT). Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during viral resistance to indinavir, a human immunodeficiency virus type 	./cache/work_ese5a35olbgtnazmyggs7tkx3u.pdf	./txt/work_ese5a35olbgtnazmyggs7tkx3u.txt