[PDF] Sensing and Responding to Hypoxia, Molecular and Physiological Mechanisms1 | Semantic Scholar Skip to search formSkip to main content> Semantic Scholar's Logo Search Sign InCreate Free Account You are currently offline. Some features of the site may not work correctly. DOI:10.1093/icb/42.3.463 Corpus ID: 919737Sensing and Responding to Hypoxia, Molecular and Physiological Mechanisms1 @inproceedings{Lutz2002SensingAR, title={Sensing and Responding to Hypoxia, Molecular and Physiological Mechanisms1}, author={P. Lutz and H. Prentice}, booktitle={Integrative and comparative biology}, year={2002} } P. Lutz, H. Prentice Published in Integrative and comparative… 2002 Biology, Medicine Abstract In order to adapt to low oxygen it is necessary first to be able to detect hypoxia, then to initiate the appropriate defense mechanisms. There are two basic detectors: molecular sensors that are directly linked to gene regulation and metabolic indicators that are triggered when the cell goes into a state of energy imbalance. The molecular responses to oxygen deprivation are characterized in a variety of cell types and include activation of oxygen sensors, signaling through specific… Expand View on BioOne academic.oup.com Save to Library Create Alert Cite Launch Research Feed Share This Paper 37 CitationsHighly Influential Citations 1 Background Citations 16 View All Topics from this paper Oxygen Hypoxia Adenosine Triphosphate Potassium Calcium Erythrocytes Blood Cells Brain Chemoreceptor Cells Pathologic Neovascularization Transcript Turtle Structure of parenchyma of lung Defense Mechanisms Anoxia Respiration FOS gene 37 Citations Citation Type Citation Type All Types Cites Results Cites Methods Cites Background Has PDF Publication Type Author More Filters More Filters Filters Sort by Relevance Sort by Most Influenced Papers Sort by Citation Count Sort by Recency Title : Oxygen sensors of the peripheral and central nervous system G. M. C. Renshaw, M. 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Jensen Biology, Medicine Physiology 2015 48 PDF View 1 excerpt, cites background Save Alert Research Feed ... 1 2 3 4 ... References SHOWING 1-10 OF 56 REFERENCES SORT BYRelevance Most Influenced Papers Recency Oxygen sensing and molecular adaptation to hypoxia. H. Bunn, R. O. Poyton Biology, Medicine Physiological reviews 1996 1,149 Highly Influential View 3 excerpts, references background Save Alert Research Feed Defense strategies against hypoxia and hypothermia. P. Hochachka Biology, Medicine Science 1986 1,011 Highly Influential View 4 excerpts, references background Save Alert Research Feed Mammalian oxygen sensing, signalling and gene regulation. R. Wenger Biology, Medicine The Journal of experimental biology 2000 457 PDF View 1 excerpt, references background Save Alert Research Feed Cellular mechanisms of oxygen sensing at the carotid body: heme proteins and ion channels. N. Prabhakar, J. L. 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