id author title date pages extension mime words sentences flesch summary cache txt work_mairtkvvofcdpp7xx5jeoujq5e S. Akila Parvathy Dharshini Investigating the energy crisis in Alzheimer disease using transcriptome study 2019 13 .pdf application/pdf 8328 947 50 differential gene/transcript expression profiles from hippocampus RNA-seq data. RNA-seq data plays an important role in identifying differential expressions, variants and fusion gene detection. From large-scale network studies, we found that most of the disrupted TFs are impacting the gene expression of Differential transcript proportion and transcript expression for (a) novel and (b) known ADassociated genes (+upregulation, −downregulation, (+/− number in brackets refer to fold change)). We observed that dysregulation of genes are associated with biological functions such as transport, metabolism, oxidative stress, lipid metabolism, ROS response, how the TFs functionally associated to differentially expressed genes. The functional interactions between important differentially expressed genes and TFs. https://doi.org/10.1038/s41598-019-54782-y Functional enrichment analysis revealed that novel differentially expressed genes are related to blood vessel In this study, we performed variant and differential expression profile analysis from hippocampus RNA-seq data. Differential gene/transcript expression analysis of hippocampus RNA-seq. Differential gene/transcript expression analysis of hippocampus RNA-seq. ./cache/work_mairtkvvofcdpp7xx5jeoujq5e.pdf ./txt/work_mairtkvvofcdpp7xx5jeoujq5e.txt