id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_fb7xkfpy5vchvoqkofgwx66qb4	Tetsuru Karasawa	Metabolome Analysis of Erythrocytes from Patients with Chronic Hepatitis C Reveals the Etiology of Ribavirin-Induced Hemolysis	2013	3	.pdf	application/pdf	1794	159	49	This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/ Ribavirin is one of the major agents used in combination therapy with interferon for chronic produced by glycolysis and the pentose phosphate cycle in patients' erythrocytes were significantly Key words: HCV, ribavirin, anemia, metabolome, glycolysis, pentose phosphate cycle. level of ATP in cells is reduced as a result of ribavirin study showed that ribavirin-induced anemia is primarily due to the effect of the drug on guanosine triphosphate, consequently leading to a reduction of pentose phosphate cycle in erythrocytes between Levels of intermediate metabolites for glycolytic system and pentose phosphate cycle in erythrocytes of patients receiving glycolysis and the pentose phosphate cycle in erythrocytes. erythrocytes were all reduced after ribavirin administration, among which that of D-ribose-5-phosphate by ribavirin therapy in patients with chronic hepatitis C virus infection: The metabolism of ribavirin in erythrocytes and 	./cache/work_fb7xkfpy5vchvoqkofgwx66qb4.pdf	./txt/work_fb7xkfpy5vchvoqkofgwx66qb4.txt