id author title date pages extension mime words sentences flesch summary cache txt work_65urskdhlbfp3jp7pqmllgjitu Kisang Kwon Expression of Beta-catenin-interacting Protein 1 (CTNNBIP1) Gene Is Increased under Hypothermia but Decreased under Additional Ischemia Conditions 2014 5 .pdf application/pdf 1911 190 57 Expression of Beta-catenin-interacting Protein 1 (CTNNBIP1) Gene It has recently been shown that hypothermia treatment improves brain ischemia injury and is being increasingly present study we demonstrated firstly that hypothermia induced beta-catenin-interacting protein 1 (CTNNBIP1) gene hypothermia activated endoplasmic reticulum (ER) stress sensors especially both, the phosphorylation of eIF2α, and These findings suggested that hypothermia controlled CTNNBIP1 gene expression under ischemia, which may provide Key Words: Hypothermia, Ischemia, CTNNBIP1, ER stress sensor gene expression in both, cells treated with hypothermia Hypothermia decreases CTNNBIP1 mRNA expression under the ischemia. Effect of hypothermia on gene expression of ER chaperones (A), XBP1 mRNA splicing (B), ER stress sensors (C), apoptosisassociated factors (D) and autophage-associated factors (E). However, the result shown in Fig. 2 demonstrated that hypothermia decreasingly modulated CTNNBIP1 mRNA expression under ischemia. Cells exposed to hypothermia had no changes in ER chaperones gene expression that hypothermia controlled CTNNBIP1 mRNA expression decreased CTNNBIP1 gene expression under ischemia, ./cache/work_65urskdhlbfp3jp7pqmllgjitu.pdf ./txt/work_65urskdhlbfp3jp7pqmllgjitu.txt