id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_zehcai3xi5bixpdbvcxbytroo4	S. Choudhary	Quantitation and Localization of Matrix Metalloproteinases and Their Inhibitors in Human Carotid Endarterectomy Tissues	2006.0	8	.pdf	application/pdf	5776	533	53	Quantitation and Localization of Matrix Metalloproteinases and Their Inhibitors in Human Carotid Endarterectomy Tissues determine the spatial distribution of TIMP mass and MMP mass and activity of carotid endarterectomy (CEA) tissues to total protein extractions and analyzed by ELISA for MMP-2 and -9 and TIMP-1 and -2 mass and by zymography for Segments at or near the bifurcation with highly calcified lesions contained higher MMP levels and activity than segments distant from the bifurcation; highly fibrotic or necrotic plaque contained lower MMP levels and Conclusion—The spatial distribution of MMPs and TIMPs in carotid atherosclerotic lesions is highly heterogeneous, MMP and TIMP levels as determined by ELISA for the human CEA tissue segments (nos. over the CEA tissues, total activity values (0 to 7 MMP-9 ng This study clearly demonstrates the longitudinal heterogeneous distribution of MMPs and TIMPS among atherosclerotic lesions and grossly normal regions within 5-mm tissue	./cache/work_zehcai3xi5bixpdbvcxbytroo4.pdf	./txt/work_zehcai3xi5bixpdbvcxbytroo4.txt