id author title date pages extension mime words sentences flesch summary cache txt work_ohiqcfcllzf37bq3iqtq5qreky Lowie M Van Assche A new CMR protocol for non-destructive, high resolution, ex-vivo assessment of the area at risk simultaneous with infarction: validation with histopathology 2012.0 2 .pdf application/pdf 684 67 46 salvage areas of ischemic, but reversibly injured myocardium within the area-at-risk (AAR). the AAR, infarction, and to calculate salvage. provides non-destructive, high-resolution, ex-vivo assessment of the AAR simultaneous with infarction. Finally, (4) the heart was extracted and ex-vivo 3-dimensional-delayed-enhancement-CMR imaging was performed. (absence of microspheres) and after staining with triphenyltetrazoliumchloride to delineate infarction. Histopathology and ex-vivo-CMR images were analyzed by 2 On an animal basis, ex-vivo-CMR AAR was similar to correlation between the ex-vivo-CMR and microspheredefined AAR (r=0.98, slope=0.96±0.04, p<00001). Similarly, CMR infarct size matched that by triphenyltetrazoliumchloride (r=0.97, p<0.0001). We developed a new CMR protocol that provides highresolution, ex-vivo images of the AAR simultaneous Cite this article as: Van Assche et al.: A new CMR protocol for nondestructive, high resolution, ex-vivo assessment of the area at risk simultaneous with infarction: validation with histopathology. Journal of Cardiovascular Magnetic Resonance 2012, 14(Suppl 1):O7 Journal of Cardiovascular Magnetic Resonance 2012, 14(Suppl 1):O7 ./cache/work_ohiqcfcllzf37bq3iqtq5qreky.pdf ./txt/work_ohiqcfcllzf37bq3iqtq5qreky.txt