id author title date pages extension mime words sentences flesch summary cache txt work_kdvhz5vtufft7hkxihnp37oyie Sylwia Lehmann Flare Size but Not Intensity Reflects Histamine-Induced Itch 2020.0 9 .pdf application/pdf 7036 1947 79 Conclusion: In histamine-induced skin inflammation, itch and increased blood flow are flare size and itch intensity are linked, reflecting the level of activation of sensory skin nerves. Also, all of these studies are limited to the characterization of the area of flare reactions and did not analyze flare intensity, and most of them only assessed histamine-induced flare and itch [19, 20]. skin blood flow that underlie histamineand cowhageinduced flare responses, to assess its links to itch Itch responses to histamine were significantly correlated with the size of the area of increased blood flow Pearson's r correlations between itch intensity and flare parameters measured 10 min after skin provocation with histamine, of increased blood flow measured using LSCI was not significantly different from the correlation between itch duration and flare area measured planimetrically from digital pictures, p = 0.140. Our results are consistent with those of previous studies in which histaminergic itch correlated with flare area assessed by LSCI and ./cache/work_kdvhz5vtufft7hkxihnp37oyie.pdf ./txt/work_kdvhz5vtufft7hkxihnp37oyie.txt