id author title date pages extension mime words sentences flesch summary cache txt work_jy3iit3v3bhu7mztr7rowuf3em Zoe Draelos Novel retinoid ester in combination with salicylic acid for the treatment of acne 2015.0 3 .pdf application/pdf 1950 186 51 Retinoids (RC), alpha hydroxy acids (AHA), and salicylic acid (SA) have therapeutic benefit in acne treatment combining the RC induced normalization of cellular differentiation, AHA induced exfoliation in hydrophilic areas, delivering both lactic acid (AHA) and RC in a time-released hydrolytic manner designed to reduce retinoid using a 3-product regimen consisting of a twice daily cleanser (7.8% l-lactic acid, 2% SA), a twice daily acne serum Investigator counts of total inflammatory (papules, pustules) and non-inflammatory (open comedones, closed comedones) lesions revealed a statistically significant reduction in inflammatory lesion counts (p=0.006) and non-inflammatory lesion counts (p=0.015) after 4 weeks of use. of lactic acid, SA and the novel AHA-RC produced acne improvement after 4 weeks with continuing cumulative l-lactic acid, 2% BHA), active topical (0.1% AHA-RC, Table 1: Acne Lesion Percent Improvement, Baseline to Week 8 effective for treatment of acne; statistically significant reductions in both Comparison of Percent Improvement in Acne Lesion Count, Baseline to Week 8 ./cache/work_jy3iit3v3bhu7mztr7rowuf3em.pdf ./txt/work_jy3iit3v3bhu7mztr7rowuf3em.txt