id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_4vjvmmhde5hjfhgapo2rhk4fwq	Y. Guo	In Vivo Bioluminescence Imaging To Evaluate Systemic and Topical Antibiotics against Community-Acquired Methicillin-Resistant Staphylococcus aureus-Infected Skin Wounds in Mice	2012.0	9	.pdf	application/pdf	9001	1136	61	mouse model of CA-MRSA wound infection to compare the efficacy of commonly used systemic and topical antibiotics. A bioluminescent USA300 CA-MRSA strain was inoculated into full-thickness scalpel wounds on the backs of mice and digital photography/image analysis and in vivo bioluminescence imaging were used to measure wound healing and the bacterial burden. mouse model of CA-MRSA wound infection, which utilizes in vivo bioluminescence imaging to monitor the bacterial burden, 2 � 105, 2 � 106, or 2 � 107 CFU of the bioluminescent CA-MRSA strain, USA300 LAC::lux, or no bacteria (none)/10 �l (n � 5 mice per group). Although pharmacokinetic studies with vancomycin, daptomyFIG 3 Efficacy of systemic (subcutaneous and oral) antibiotics against CA-MRSA-infected wounds. FIG 5 Efficacy of subcutaneous vancomycin, daptomycin, and linezolid against a CA-MRSA wound infection in diabetic mice. Mouse model of CA-MRSA skin wound infection using in vivo bioluminescence imaging. Mouse model of CA-MRSA skin wound infection using in vivo bioluminescence imaging.	./cache/work_4vjvmmhde5hjfhgapo2rhk4fwq.pdf	./txt/work_4vjvmmhde5hjfhgapo2rhk4fwq.txt