id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
en-wikipedia-org-6976		Dopamine - Wikipedia			.html	text/html	15749	2533	59	While dopamine has a central role in causing "wanting," associated with the appetitive or approach behavioral responses to rewarding stimuli, detailed studies have shown that dopamine cannot simply be equated with hedonic "liking" or pleasure, as reflected in the consummatory behavioral response.[52] Dopamine neurotransmission is involved in some but not all aspects of pleasure-related cognition, since pleasure centers have been identified both within the dopamine system (i.e., nucleus accumbens shell) and outside the dopamine system (i.e., ventral pallidum and parabrachial nucleus).[52][54][58] For example, direct electrical stimulation of dopamine pathways, using electrodes implanted in the brain, is experienced as pleasurable, and many types of animals are willing to work to obtain it.[59] Antipsychotic drugs reduce dopamine levels and tend to cause anhedonia, a diminished ability to experience pleasure.[60] Many types of pleasurable experiences—such as sex, eating, and playing video games—increase dopamine release.[61] All addictive drugs directly or indirectly affect dopamine neurotransmission in the nucleus accumbens;[3][59] these drugs increase drug "wanting", leading to compulsive drug use, when repeatedly taken in high doses, presumably through the sensitization of incentive-salience.[54] Drugs that increase synaptic dopamine concentrations include psychostimulants such as methamphetamine and cocaine.	./cache/en-wikipedia-org-6976.html	./txt/en-wikipedia-org-6976.txt