id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
en-wikipedia-org-5566		Irritability - Wikipedia			.html	text/html	2165	399	44	However, it is not particularly specific to irritability, as frustration is its own construct with a number of emotional and behavioral associations.[10][11] A second prominent special definition describes a group of behavioral issues often occurring in those diagnosed with an autism spectrum disorder.[12] This deserves mention here because this version of irritability has been a commonly used in a number of clinical trials and defines the current US Food and Drug Administration irritability indication. Irritability is associated with a number of mental health conditions.[13] It is a defining characteristic of any mood disorder, such as bipolar, depressive, and disruptive mood dysregulation disorders.[13] It is also a major feature of a number of other disorders, including autism spectrum disorders, traumatic stress disorders, generalized anxiety disorder, etc.[6] Finally, it is a notable characteristic of delirium, dementia, hormonal change, metabolic disturbance, chronic stress, pain, and substance/medication withdrawal.	./cache/en-wikipedia-org-5566.html	./txt/en-wikipedia-org-5566.txt