id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-302268-dmb0293x	Lee, Sujin	Recent Advances of Vaccine Adjuvants for Infectious Diseases	2015-04-23		.txt	text/plain	3731	224	43	Immunologic adjuvants are essential for enhancing vaccine potency by improvement of the humoral and/or cell-mediated immune response to vaccine antigens. Immunologic adjuvants are essential for enhancing vaccine potency by improvement of the humoral and/or cell-mediated immune response to vaccine antigens. Vaccines made from live-attenuated or inactivated pathogens can elicit robust protective immune responses because those vaccines contain naturally occurring adjuvants. A benefit of using AS04 adjuvant in human vaccines is the effective induction of robust Th1-type immune responses by promoting IL-2 and IFN-γ production, which cannot be achieved by using alum alone. Thus, flagellin fusion proteins are suitable adjuvants for the development of vaccines to induce robust antigen-specific immune responses. Main benefits of these adjuvants are induction of high and long-lasting antibody titer, induction of balanced Th1 and Th2 type immunity, and induction of CMI including cytotoxic T cell response (42) .	./cache/cord-302268-dmb0293x.txt	./txt/cord-302268-dmb0293x.txt