id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-001866-s5otdtwq	Mandal, Nakul	Proteomic Analysis of the Vitreous following Experimental Retinal Detachment in Rabbits	2015-11-18		.txt	text/plain	4553	227	38	Here we investigate the protein profile of the vitreous following experimental retinal detachment using a comparative proteomic based approach. Protein spots that were upregulated in the vitreous following retinal detachment were identified as albumin fragments, and those downregulated were found to be peroxiredoxin 2, collagen-Iα1 fragment, and α-1-antiproteinase F. Proteomic investigation of the rabbit vitreous has identified a set of proteins that help further our understanding of the pathogenesis of rhegmatogenous retinal detachment and its complications. All well-defined protein spots that were at least twofold (Mann-Whitney test, < 0.05) differentially expressed between the sham and retinal detachment vitreous groups were selected for identification with nanoliquid chromatographyelectrospray ionization tandem mass spectrometry (LC-MS/MS). This proteomic investigation of the rabbit vitreous has identified a set of proteins that assist our understanding of the pathogenesis of rhegmatogenous retinal detachment and its Journal of Ophthalmology 7 complications.	./cache/cord-001866-s5otdtwq.txt	./txt/cord-001866-s5otdtwq.txt