id	sid	tid	token	lemma	pos
cord-103536-etin5i7y	1	1	key	key	NN
cord-103536-etin5i7y	1	2	:	:	:
cord-103536-etin5i7y	2	1	cord-103536-etin5i7y	cord-103536-etin5i7y	NNP
cord-103536-etin5i7y	2	2	authors	author	NNS
cord-103536-etin5i7y	2	3	:	:	:
cord-103536-etin5i7y	2	4	Timmins	Timmins	NNP
cord-103536-etin5i7y	2	5	,	,	,
cord-103536-etin5i7y	2	6	Joanna	Joanna	NNP
cord-103536-etin5i7y	2	7	;	;	:
cord-103536-etin5i7y	2	8	Ruigrok	Ruigrok	NNP
cord-103536-etin5i7y	2	9	,	,	,
cord-103536-etin5i7y	2	10	Rob	Rob	NNP
cord-103536-etin5i7y	2	11	W.H.	W.H.	NNP
cord-103536-etin5i7y	2	12	;	;	:
cord-103536-etin5i7y	2	13	Weissenhorn	Weissenhorn	NNP
cord-103536-etin5i7y	2	14	,	,	,
cord-103536-etin5i7y	2	15	Winfried	Winfried	NNP
cord-103536-etin5i7y	2	16	title	title	NN
cord-103536-etin5i7y	2	17	:	:	:
cord-103536-etin5i7y	2	18	Structural	structural	JJ
cord-103536-etin5i7y	2	19	studies	study	NNS
cord-103536-etin5i7y	2	20	on	on	IN
cord-103536-etin5i7y	2	21	the	the	DT
cord-103536-etin5i7y	2	22	Ebola	Ebola	NNP
cord-103536-etin5i7y	2	23	virus	virus	NN
cord-103536-etin5i7y	2	24	matrix	matrix	NN
cord-103536-etin5i7y	2	25	protein	protein	NN
cord-103536-etin5i7y	3	1	VP40	VP40	NNP
cord-103536-etin5i7y	3	2	indicate	indicate	VBP
cord-103536-etin5i7y	3	3	that	that	IN
cord-103536-etin5i7y	3	4	matrix	matrix	NN
cord-103536-etin5i7y	3	5	proteins	protein	NNS
cord-103536-etin5i7y	3	6	of	of	IN
cord-103536-etin5i7y	3	7	enveloped	envelop	VBN
cord-103536-etin5i7y	3	8	RNA	RNA	NNP
cord-103536-etin5i7y	3	9	viruses	virus	NNS
cord-103536-etin5i7y	3	10	are	be	VBP
cord-103536-etin5i7y	3	11	analogues	analogue	NNS
cord-103536-etin5i7y	3	12	but	but	CC
cord-103536-etin5i7y	3	13	not	not	RB
cord-103536-etin5i7y	3	14	homologues	homologue	NNS
cord-103536-etin5i7y	3	15	date	date	NN
cord-103536-etin5i7y	4	1	:	:	:
cord-103536-etin5i7y	4	2	2004	2004	CD
cord-103536-etin5i7y	4	3	-	-	HYPH
cord-103536-etin5i7y	4	4	04	04	CD
cord-103536-etin5i7y	4	5	-	-	SYM
cord-103536-etin5i7y	4	6	15	15	CD
cord-103536-etin5i7y	4	7	journal	journal	NN
cord-103536-etin5i7y	4	8	:	:	:
cord-103536-etin5i7y	5	1	FEMS	FEMS	NNP
cord-103536-etin5i7y	5	2	Microbiology	Microbiology	NNP
cord-103536-etin5i7y	5	3	Letters	Letters	NNPS
cord-103536-etin5i7y	5	4	DOI	DOI	NNP
cord-103536-etin5i7y	5	5	:	:	:
cord-103536-etin5i7y	5	6	10.1016	10.1016	CD
cord-103536-etin5i7y	6	1	/j.femsle.2004.03.002	/j.femsle.2004.03.002	NFP
cord-103536-etin5i7y	6	2	sha	sha	NNP
cord-103536-etin5i7y	6	3	:	:	:
cord-103536-etin5i7y	7	1	9e913d44d395e3e7a3d1a7d38559d8ab430bebbe	9e913d44d395e3e7a3d1a7d38559d8ab430bebbe	CD
cord-103536-etin5i7y	7	2	doc_id	doc_id	CD
cord-103536-etin5i7y	7	3	:	:	:
cord-103536-etin5i7y	7	4	103536	103536	CD
cord-103536-etin5i7y	7	5	cord_uid	cord_uid	FW
cord-103536-etin5i7y	7	6	:	:	:
cord-103536-etin5i7y	8	1	etin5i7y	etin5i7y	NNP
cord-103536-etin5i7y	8	2	Abstract	Abstract	NNP
cord-103536-etin5i7y	8	3	Matrix	Matrix	NNP
cord-103536-etin5i7y	8	4	proteins	protein	NNS
cord-103536-etin5i7y	8	5	are	be	VBP
cord-103536-etin5i7y	8	6	the	the	DT
cord-103536-etin5i7y	8	7	driving	drive	VBG
cord-103536-etin5i7y	8	8	force	force	NN
cord-103536-etin5i7y	8	9	of	of	IN
cord-103536-etin5i7y	8	10	assembly	assembly	NN
cord-103536-etin5i7y	8	11	of	of	IN
cord-103536-etin5i7y	8	12	enveloped	enveloped	JJ
cord-103536-etin5i7y	8	13	viruses	virus	NNS
cord-103536-etin5i7y	8	14	.	.	.
cord-103536-etin5i7y	9	1	Their	-PRON-	PRP$
cord-103536-etin5i7y	9	2	main	main	JJ
cord-103536-etin5i7y	9	3	function	function	NN
cord-103536-etin5i7y	9	4	is	be	VBZ
cord-103536-etin5i7y	9	5	to	to	TO
cord-103536-etin5i7y	9	6	interact	interact	VB
cord-103536-etin5i7y	9	7	with	with	IN
cord-103536-etin5i7y	9	8	and	and	CC
cord-103536-etin5i7y	9	9	polymerize	polymerize	VB
cord-103536-etin5i7y	9	10	at	at	IN
cord-103536-etin5i7y	9	11	cellular	cellular	JJ
cord-103536-etin5i7y	9	12	membranes	membrane	NNS
cord-103536-etin5i7y	9	13	and	and	CC
cord-103536-etin5i7y	9	14	link	link	VBP
cord-103536-etin5i7y	9	15	other	other	JJ
cord-103536-etin5i7y	9	16	viral	viral	JJ
cord-103536-etin5i7y	9	17	components	component	NNS
cord-103536-etin5i7y	9	18	to	to	IN
cord-103536-etin5i7y	9	19	the	the	DT
cord-103536-etin5i7y	9	20	matrix	matrix	NN
cord-103536-etin5i7y	9	21	–	–	:
cord-103536-etin5i7y	9	22	membrane	membrane	NN
cord-103536-etin5i7y	9	23	complex	complex	NN
cord-103536-etin5i7y	9	24	resulting	result	VBG
cord-103536-etin5i7y	9	25	in	in	IN
cord-103536-etin5i7y	9	26	individual	individual	JJ
cord-103536-etin5i7y	9	27	particle	particle	NN
cord-103536-etin5i7y	9	28	shapes	shape	NNS
cord-103536-etin5i7y	9	29	and	and	CC
cord-103536-etin5i7y	9	30	ensuring	ensure	VBG
cord-103536-etin5i7y	9	31	the	the	DT
cord-103536-etin5i7y	9	32	integrity	integrity	NN
cord-103536-etin5i7y	9	33	of	of	IN
cord-103536-etin5i7y	9	34	the	the	DT
cord-103536-etin5i7y	9	35	viral	viral	JJ
cord-103536-etin5i7y	9	36	particle	particle	NN
cord-103536-etin5i7y	9	37	.	.	.
cord-103536-etin5i7y	10	1	Although	although	IN
cord-103536-etin5i7y	10	2	matrix	matrix	NN
cord-103536-etin5i7y	10	3	proteins	protein	NNS
cord-103536-etin5i7y	10	4	of	of	IN
cord-103536-etin5i7y	10	5	different	different	JJ
cord-103536-etin5i7y	10	6	virus	virus	NN
cord-103536-etin5i7y	10	7	families	family	NNS
cord-103536-etin5i7y	10	8	show	show	VBP
cord-103536-etin5i7y	10	9	functional	functional	JJ
cord-103536-etin5i7y	10	10	analogy	analogy	NN
cord-103536-etin5i7y	10	11	,	,	,
cord-103536-etin5i7y	10	12	they	-PRON-	PRP
cord-103536-etin5i7y	10	13	share	share	VBP
cord-103536-etin5i7y	10	14	no	no	DT
cord-103536-etin5i7y	10	15	sequence	sequence	NN
cord-103536-etin5i7y	10	16	or	or	CC
cord-103536-etin5i7y	10	17	structural	structural	JJ
cord-103536-etin5i7y	10	18	homology	homology	NN
cord-103536-etin5i7y	10	19	.	.	.
cord-103536-etin5i7y	11	1	Their	-PRON-	PRP$
cord-103536-etin5i7y	11	2	diversity	diversity	NN
cord-103536-etin5i7y	11	3	is	be	VBZ
cord-103536-etin5i7y	11	4	also	also	RB
cord-103536-etin5i7y	11	5	evident	evident	JJ
cord-103536-etin5i7y	11	6	in	in	IN
cord-103536-etin5i7y	11	7	that	that	IN
cord-103536-etin5i7y	11	8	they	-PRON-	PRP
cord-103536-etin5i7y	11	9	use	use	VBP
cord-103536-etin5i7y	11	10	a	a	DT
cord-103536-etin5i7y	11	11	variety	variety	NN
cord-103536-etin5i7y	11	12	of	of	IN
cord-103536-etin5i7y	11	13	late	late	JJ
cord-103536-etin5i7y	11	14	domain	domain	NN
cord-103536-etin5i7y	11	15	motifs	motif	NNS
cord-103536-etin5i7y	11	16	to	to	TO
cord-103536-etin5i7y	11	17	commit	commit	VB
cord-103536-etin5i7y	11	18	the	the	DT
cord-103536-etin5i7y	11	19	cellular	cellular	JJ
cord-103536-etin5i7y	11	20	vacuolar	vacuolar	NNP
cord-103536-etin5i7y	11	21	protein	protein	NN
cord-103536-etin5i7y	11	22	sorting	sort	VBG
cord-103536-etin5i7y	11	23	machinery	machinery	NN
cord-103536-etin5i7y	11	24	to	to	IN
cord-103536-etin5i7y	11	25	virus	virus	NN
cord-103536-etin5i7y	11	26	budding	bud	VBG
cord-103536-etin5i7y	11	27	.	.	.
cord-103536-etin5i7y	12	1	Here	here	RB
cord-103536-etin5i7y	12	2	,	,	,
cord-103536-etin5i7y	12	3	we	-PRON-	PRP
cord-103536-etin5i7y	12	4	discuss	discuss	VBP
cord-103536-etin5i7y	12	5	the	the	DT
cord-103536-etin5i7y	12	6	structural	structural	JJ
cord-103536-etin5i7y	12	7	and	and	CC
cord-103536-etin5i7y	12	8	functional	functional	JJ
cord-103536-etin5i7y	12	9	aspects	aspect	NNS
cord-103536-etin5i7y	12	10	of	of	IN
cord-103536-etin5i7y	12	11	the	the	DT
cord-103536-etin5i7y	12	12	filovirus	filovirus	NN
cord-103536-etin5i7y	12	13	matrix	matrix	NN
cord-103536-etin5i7y	12	14	protein	protein	NN
cord-103536-etin5i7y	12	15	VP40	VP40	NNP
cord-103536-etin5i7y	12	16	and	and	CC
cord-103536-etin5i7y	12	17	compare	compare	VB
cord-103536-etin5i7y	12	18	them	-PRON-	PRP
cord-103536-etin5i7y	12	19	to	to	IN
cord-103536-etin5i7y	12	20	other	other	JJ
cord-103536-etin5i7y	12	21	known	know	VBN
cord-103536-etin5i7y	12	22	matrix	matrix	NN
cord-103536-etin5i7y	12	23	protein	protein	NN
cord-103536-etin5i7y	12	24	structures	structure	NNS
cord-103536-etin5i7y	12	25	from	from	IN
cord-103536-etin5i7y	12	26	vesicular	vesicular	JJ
cord-103536-etin5i7y	12	27	stomatitis	stomatitis	NN
cord-103536-etin5i7y	12	28	virus	virus	NN
cord-103536-etin5i7y	12	29	,	,	,
cord-103536-etin5i7y	12	30	influenza	influenza	NN
cord-103536-etin5i7y	12	31	virus	virus	NN
cord-103536-etin5i7y	12	32	and	and	CC
cord-103536-etin5i7y	12	33	retroviral	retroviral	NN
cord-103536-etin5i7y	12	34	matrix	matrix	NN
cord-103536-etin5i7y	12	35	proteins	protein	NNS
cord-103536-etin5i7y	12	36	.	.	.
cord-103536-etin5i7y	13	1	Enveloped	Enveloped	NNP
cord-103536-etin5i7y	13	2	RNA	RNA	NNP
cord-103536-etin5i7y	13	3	viruses	virus	NNS
cord-103536-etin5i7y	13	4	from	from	IN
cord-103536-etin5i7y	13	5	the	the	DT
cord-103536-etin5i7y	13	6	families	family	NNS
cord-103536-etin5i7y	13	7	of	of	IN
cord-103536-etin5i7y	13	8	Filoviridae	Filoviridae	NNP
cord-103536-etin5i7y	13	9	,	,	,
cord-103536-etin5i7y	13	10	Paramyxoviridae	Paramyxoviridae	NNP
cord-103536-etin5i7y	13	11	,	,	,
cord-103536-etin5i7y	13	12	Rhabdoviridae	Rhabdoviridae	NNP
cord-103536-etin5i7y	13	13	and	and	CC
cord-103536-etin5i7y	13	14	Bornaviridae	Bornaviridae	NNP
cord-103536-etin5i7y	13	15	(	(	-LRB-
cord-103536-etin5i7y	13	16	constituting	constitute	VBG
cord-103536-etin5i7y	13	17	the	the	DT
cord-103536-etin5i7y	13	18	order	order	NN
cord-103536-etin5i7y	13	19	Mononegavirales	Mononegavirales	NNP
cord-103536-etin5i7y	13	20	)	)	-RRB-
cord-103536-etin5i7y	13	21	,	,	,
cord-103536-etin5i7y	13	22	Orthomyxoviridae	Orthomyxoviridae	NNP
cord-103536-etin5i7y	13	23	and	and	CC
cord-103536-etin5i7y	13	24	Retroviridae	Retroviridae	NNP
cord-103536-etin5i7y	13	25	are	be	VBP
cord-103536-etin5i7y	13	26	a	a	DT
cord-103536-etin5i7y	13	27	morphologically	morphologically	RB
cord-103536-etin5i7y	13	28	diverse	diverse	JJ
cord-103536-etin5i7y	13	29	group	group	NN
cord-103536-etin5i7y	13	30	of	of	IN
cord-103536-etin5i7y	13	31	viruses	virus	NNS
cord-103536-etin5i7y	13	32	.	.	.
cord-103536-etin5i7y	14	1	The	the	DT
cord-103536-etin5i7y	14	2	viral	viral	JJ
cord-103536-etin5i7y	14	3	shape	shape	NN
cord-103536-etin5i7y	14	4	is	be	VBZ
cord-103536-etin5i7y	14	5	determined	determine	VBN
cord-103536-etin5i7y	14	6	by	by	IN
cord-103536-etin5i7y	14	7	the	the	DT
cord-103536-etin5i7y	14	8	matrix	matrix	NN
cord-103536-etin5i7y	14	9	protein	protein	NN
cord-103536-etin5i7y	14	10	and	and	CC
cord-103536-etin5i7y	14	11	the	the	DT
cord-103536-etin5i7y	14	12	nucleocapsid	nucleocapsid	NN
cord-103536-etin5i7y	14	13	that	that	WDT
cord-103536-etin5i7y	14	14	are	be	VBP
cord-103536-etin5i7y	14	15	responsible	responsible	JJ
cord-103536-etin5i7y	14	16	for	for	IN
cord-103536-etin5i7y	14	17	producing	produce	VBG
cord-103536-etin5i7y	14	18	spherical	spherical	JJ
cord-103536-etin5i7y	14	19	,	,	,
cord-103536-etin5i7y	14	20	rod	rod	NN
cord-103536-etin5i7y	14	21	-	-	HYPH
cord-103536-etin5i7y	14	22	shaped	shape	VBN
cord-103536-etin5i7y	14	23	,	,	,
cord-103536-etin5i7y	14	24	bullet	bullet	NN
cord-103536-etin5i7y	14	25	-	-	HYPH
cord-103536-etin5i7y	14	26	shaped	shape	VBN
cord-103536-etin5i7y	14	27	or	or	CC
cord-103536-etin5i7y	14	28	bacilliform	bacilliform	NN
cord-103536-etin5i7y	14	29	particles	particle	NNS
cord-103536-etin5i7y	14	30	.	.	.
cord-103536-etin5i7y	15	1	Viral	viral	JJ
cord-103536-etin5i7y	15	2	matrix	matrix	NN
cord-103536-etin5i7y	15	3	proteins	protein	NNS
cord-103536-etin5i7y	15	4	generally	generally	RB
cord-103536-etin5i7y	15	5	constitute	constitute	VBP
cord-103536-etin5i7y	15	6	a	a	DT
cord-103536-etin5i7y	15	7	major	major	JJ
cord-103536-etin5i7y	15	8	structural	structural	JJ
cord-103536-etin5i7y	15	9	protein	protein	NN
cord-103536-etin5i7y	15	10	of	of	IN
cord-103536-etin5i7y	15	11	the	the	DT
cord-103536-etin5i7y	15	12	viral	viral	JJ
cord-103536-etin5i7y	15	13	particle	particle	NN
cord-103536-etin5i7y	15	14	and	and	CC
cord-103536-etin5i7y	15	15	are	be	VBP
cord-103536-etin5i7y	15	16	located	locate	VBN
cord-103536-etin5i7y	15	17	underneath	underneath	IN
cord-103536-etin5i7y	15	18	the	the	DT
cord-103536-etin5i7y	15	19	viral	viral	JJ
cord-103536-etin5i7y	15	20	membrane	membrane	NN
cord-103536-etin5i7y	15	21	.	.	.
cord-103536-etin5i7y	16	1	During	during	IN
cord-103536-etin5i7y	16	2	the	the	DT
cord-103536-etin5i7y	16	3	assembly	assembly	NN
cord-103536-etin5i7y	16	4	process	process	NN
cord-103536-etin5i7y	16	5	in	in	IN
cord-103536-etin5i7y	16	6	a	a	DT
cord-103536-etin5i7y	16	7	host	host	NN
cord-103536-etin5i7y	16	8	cell	cell	NN
cord-103536-etin5i7y	16	9	,	,	,
cord-103536-etin5i7y	16	10	matrix	matrix	NN
cord-103536-etin5i7y	16	11	proteins	protein	NNS
cord-103536-etin5i7y	16	12	self	self	NN
cord-103536-etin5i7y	16	13	-	-	HYPH
cord-103536-etin5i7y	16	14	assemble	assemble	VBP
cord-103536-etin5i7y	16	15	into	into	IN
cord-103536-etin5i7y	16	16	higher	high	JJR
cord-103536-etin5i7y	16	17	-	-	HYPH
cord-103536-etin5i7y	16	18	order	order	NN
cord-103536-etin5i7y	16	19	oligomers	oligomer	NNS
cord-103536-etin5i7y	16	20	and/or	and/or	CC
cord-103536-etin5i7y	16	21	polymerise	polymerise	NN
cord-103536-etin5i7y	16	22	at	at	IN
cord-103536-etin5i7y	16	23	cellular	cellular	JJ
cord-103536-etin5i7y	16	24	membranes	membrane	NNS
cord-103536-etin5i7y	16	25	[	[	-LRB-
cord-103536-etin5i7y	16	26	1	1	CD
cord-103536-etin5i7y	16	27	,	,	,
cord-103536-etin5i7y	16	28	2	2	CD
cord-103536-etin5i7y	16	29	]	]	-RRB-
cord-103536-etin5i7y	16	30	.	.	.
cord-103536-etin5i7y	17	1	They	-PRON-	PRP
cord-103536-etin5i7y	17	2	display	display	VBP
cord-103536-etin5i7y	17	3	a	a	DT
cord-103536-etin5i7y	17	4	high	high	JJ
cord-103536-etin5i7y	17	5	tendency	tendency	NN
cord-103536-etin5i7y	17	6	to	to	TO
cord-103536-etin5i7y	17	7	aggregate	aggregate	VB
cord-103536-etin5i7y	17	8	in	in	IN
cord-103536-etin5i7y	17	9	vitro	vitro	FW
cord-103536-etin5i7y	17	10	,	,	,
cord-103536-etin5i7y	17	11	which	which	WDT
cord-103536-etin5i7y	17	12	may	may	MD
cord-103536-etin5i7y	17	13	reflect	reflect	VB
cord-103536-etin5i7y	17	14	their	-PRON-	PRP$
cord-103536-etin5i7y	17	15	ability	ability	NN
cord-103536-etin5i7y	17	16	to	to	TO
cord-103536-etin5i7y	17	17	self	self	NN
cord-103536-etin5i7y	17	18	-	-	HYPH
cord-103536-etin5i7y	17	19	assemble	assemble	VB
cord-103536-etin5i7y	17	20	in	in	IN
cord-103536-etin5i7y	17	21	vivo	vivo	NN
cord-103536-etin5i7y	17	22	.	.	.
cord-103536-etin5i7y	18	1	Matrix	matrix	NN
cord-103536-etin5i7y	18	2	proteins	protein	NNS
cord-103536-etin5i7y	18	3	interact	interact	VBP
cord-103536-etin5i7y	18	4	with	with	IN
cord-103536-etin5i7y	18	5	membranes	membrane	NNS
cord-103536-etin5i7y	18	6	and	and	CC
cord-103536-etin5i7y	18	7	evidence	evidence	NN
cord-103536-etin5i7y	18	8	suggests	suggest	VBZ
cord-103536-etin5i7y	18	9	that	that	IN
cord-103536-etin5i7y	18	10	they	-PRON-	PRP
cord-103536-etin5i7y	18	11	provide	provide	VBP
cord-103536-etin5i7y	18	12	a	a	DT
cord-103536-etin5i7y	18	13	link	link	NN
cord-103536-etin5i7y	18	14	between	between	IN
cord-103536-etin5i7y	18	15	the	the	DT
cord-103536-etin5i7y	18	16	cytoplasmic	cytoplasmic	JJ
cord-103536-etin5i7y	18	17	tails	tail	NNS
cord-103536-etin5i7y	18	18	of	of	IN
cord-103536-etin5i7y	18	19	the	the	DT
cord-103536-etin5i7y	18	20	glycoproteins	glycoprotein	NNS
cord-103536-etin5i7y	18	21	and	and	CC
cord-103536-etin5i7y	18	22	the	the	DT
cord-103536-etin5i7y	18	23	nucleocapsids	nucleocapsid	NNS
cord-103536-etin5i7y	18	24	that	that	WDT
cord-103536-etin5i7y	18	25	contain	contain	VBP
cord-103536-etin5i7y	18	26	the	the	DT
cord-103536-etin5i7y	18	27	RNA	RNA	NNP
cord-103536-etin5i7y	18	28	genome	genome	NN
cord-103536-etin5i7y	18	29	within	within	IN
cord-103536-etin5i7y	18	30	the	the	DT
cord-103536-etin5i7y	18	31	viral	viral	JJ
cord-103536-etin5i7y	18	32	particle	particle	NN
cord-103536-etin5i7y	18	33	[	[	-LRB-
cord-103536-etin5i7y	18	34	2	2	CD
cord-103536-etin5i7y	18	35	]	]	-RRB-
cord-103536-etin5i7y	18	36	.	.	.
cord-103536-etin5i7y	19	1	Although	although	IN
cord-103536-etin5i7y	19	2	in	in	IN
cord-103536-etin5i7y	19	3	some	some	DT
cord-103536-etin5i7y	19	4	cases	case	NNS
cord-103536-etin5i7y	19	5	matrix	matrix	NN
cord-103536-etin5i7y	19	6	protein	protein	NN
cord-103536-etin5i7y	19	7	expression	expression	NN
cord-103536-etin5i7y	19	8	in	in	IN
cord-103536-etin5i7y	19	9	eukaryotic	eukaryotic	JJ
cord-103536-etin5i7y	19	10	cells	cell	NNS
cord-103536-etin5i7y	19	11	is	be	VBZ
cord-103536-etin5i7y	19	12	sufficient	sufficient	JJ
cord-103536-etin5i7y	19	13	to	to	TO
cord-103536-etin5i7y	19	14	induce	induce	VB
cord-103536-etin5i7y	19	15	virus	virus	NN
cord-103536-etin5i7y	19	16	-	-	HYPH
cord-103536-etin5i7y	19	17	like	like	JJ
cord-103536-etin5i7y	19	18	particles	particle	NNS
cord-103536-etin5i7y	19	19	(	(	-LRB-
cord-103536-etin5i7y	19	20	VLPs	vlp	NNS
cord-103536-etin5i7y	19	21	)	)	-RRB-
cord-103536-etin5i7y	19	22	[	[	-LRB-
cord-103536-etin5i7y	19	23	3	3	CD
cord-103536-etin5i7y	19	24	]	]	-RRB-
cord-103536-etin5i7y	19	25	[	[	-LRB-
cord-103536-etin5i7y	19	26	4	4	CD
cord-103536-etin5i7y	19	27	]	]	-RRB-
cord-103536-etin5i7y	19	28	[	[	-LRB-
cord-103536-etin5i7y	19	29	5	5	CD
cord-103536-etin5i7y	19	30	]	]	-RRB-
cord-103536-etin5i7y	19	31	,	,	.
cord-103536-etin5i7y	20	1	the	the	DT
cord-103536-etin5i7y	20	2	structural	structural	JJ
cord-103536-etin5i7y	20	3	requirements	requirement	NNS
cord-103536-etin5i7y	20	4	for	for	IN
cord-103536-etin5i7y	20	5	such	such	JJ
cord-103536-etin5i7y	20	6	ordered	order	VBN
cord-103536-etin5i7y	20	7	membrane	membrane	NN
cord-103536-etin5i7y	20	8	-	-	HYPH
cord-103536-etin5i7y	20	9	associated	associate	VBN
cord-103536-etin5i7y	20	10	polymerisation	polymerisation	NN
cord-103536-etin5i7y	20	11	reactions	reaction	NNS
cord-103536-etin5i7y	20	12	are	be	VBP
cord-103536-etin5i7y	20	13	not	not	RB
cord-103536-etin5i7y	20	14	well	well	RB
cord-103536-etin5i7y	20	15	understood	understand	VBN
cord-103536-etin5i7y	20	16	and	and	CC
cord-103536-etin5i7y	20	17	often	often	RB
cord-103536-etin5i7y	20	18	depend	depend	VB
cord-103536-etin5i7y	20	19	on	on	IN
cord-103536-etin5i7y	20	20	other	other	JJ
cord-103536-etin5i7y	20	21	viral	viral	JJ
cord-103536-etin5i7y	20	22	components	component	NNS
cord-103536-etin5i7y	20	23	such	such	JJ
cord-103536-etin5i7y	20	24	as	as	IN
cord-103536-etin5i7y	20	25	the	the	DT
cord-103536-etin5i7y	20	26	glycoprotein	glycoprotein	NN
cord-103536-etin5i7y	20	27	[	[	-LRB-
cord-103536-etin5i7y	20	28	2	2	CD
cord-103536-etin5i7y	20	29	]	]	-RRB-
cord-103536-etin5i7y	20	30	.	.	.
cord-103536-etin5i7y	21	1	In	in	IN
cord-103536-etin5i7y	21	2	addition	addition	NN
cord-103536-etin5i7y	21	3	,	,	,
cord-103536-etin5i7y	21	4	cellular	cellular	JJ
cord-103536-etin5i7y	21	5	factors	factor	NNS
cord-103536-etin5i7y	21	6	modulating	modulate	VBG
cord-103536-etin5i7y	21	7	membrane	membrane	NN
cord-103536-etin5i7y	21	8	structures	structure	NNS
cord-103536-etin5i7y	21	9	might	may	MD
cord-103536-etin5i7y	21	10	play	play	VB
cord-103536-etin5i7y	21	11	a	a	DT
cord-103536-etin5i7y	21	12	role	role	NN
cord-103536-etin5i7y	21	13	.	.	.
cord-103536-etin5i7y	22	1	Consequently	consequently	RB
cord-103536-etin5i7y	22	2	,	,	,
cord-103536-etin5i7y	22	3	no	no	DT
cord-103536-etin5i7y	22	4	virus	virus	NN
cord-103536-etin5i7y	22	5	-	-	HYPH
cord-103536-etin5i7y	22	6	like	like	JJ
cord-103536-etin5i7y	22	7	particles	particle	NNS
cord-103536-etin5i7y	22	8	have	have	VBP
cord-103536-etin5i7y	22	9	yet	yet	RB
cord-103536-etin5i7y	22	10	been	be	VBN
cord-103536-etin5i7y	22	11	produced	produce	VBN
cord-103536-etin5i7y	22	12	from	from	IN
cord-103536-etin5i7y	22	13	soluble	soluble	JJ
cord-103536-etin5i7y	22	14	matrix	matrix	NN
cord-103536-etin5i7y	22	15	proteins	protein	NNS
cord-103536-etin5i7y	22	16	and	and	CC
cord-103536-etin5i7y	22	17	artificial	artificial	JJ
cord-103536-etin5i7y	22	18	lipid	lipid	NN
cord-103536-etin5i7y	22	19	bilayers	bilayer	NNS
cord-103536-etin5i7y	22	20	in	in	IN
cord-103536-etin5i7y	22	21	vitro	vitro	FW
cord-103536-etin5i7y	22	22	.	.	.
cord-103536-etin5i7y	23	1	In	in	IN
cord-103536-etin5i7y	23	2	contrast	contrast	NN
cord-103536-etin5i7y	23	3	to	to	IN
cord-103536-etin5i7y	23	4	segmented	segmented	JJ
cord-103536-etin5i7y	23	5	and	and	CC
cord-103536-etin5i7y	23	6	non	non	JJ
cord-103536-etin5i7y	23	7	-	-	JJ
cord-103536-etin5i7y	23	8	segmented	segmented	JJ
cord-103536-etin5i7y	23	9	negative	negative	JJ
cord-103536-etin5i7y	23	10	strand	strand	NN
cord-103536-etin5i7y	23	11	viruses	virus	NNS
cord-103536-etin5i7y	23	12	,	,	,
cord-103536-etin5i7y	23	13	retroviral	retroviral	JJ
cord-103536-etin5i7y	23	14	matrix	matrix	NN
cord-103536-etin5i7y	23	15	proteins	protein	NNS
cord-103536-etin5i7y	23	16	are	be	VBP
cord-103536-etin5i7y	23	17	initially	initially	RB
cord-103536-etin5i7y	23	18	part	part	NN
cord-103536-etin5i7y	23	19	of	of	IN
cord-103536-etin5i7y	23	20	the	the	DT
cord-103536-etin5i7y	23	21	Gag	Gag	NNP
cord-103536-etin5i7y	23	22	poly	poly	NN
cord-103536-etin5i7y	23	23	-	-	HYPH
cord-103536-etin5i7y	23	24	protein	protein	NN
cord-103536-etin5i7y	23	25	.	.	.
cord-103536-etin5i7y	24	1	Expression	expression	NN
cord-103536-etin5i7y	24	2	of	of	IN
cord-103536-etin5i7y	24	3	Gag	Gag	NNP
cord-103536-etin5i7y	24	4	is	be	VBZ
cord-103536-etin5i7y	24	5	largely	largely	RB
cord-103536-etin5i7y	24	6	sufficient	sufficient	JJ
cord-103536-etin5i7y	24	7	to	to	TO
cord-103536-etin5i7y	24	8	perform	perform	VB
cord-103536-etin5i7y	24	9	virus	virus	NN
cord-103536-etin5i7y	24	10	assembly	assembly	NN
cord-103536-etin5i7y	24	11	and	and	CC
cord-103536-etin5i7y	24	12	budding	bud	VBG
cord-103536-etin5i7y	24	13	at	at	IN
cord-103536-etin5i7y	24	14	the	the	DT
cord-103536-etin5i7y	24	15	plasma	plasma	NN
cord-103536-etin5i7y	24	16	membrane	membrane	NN
cord-103536-etin5i7y	24	17	which	which	WDT
cord-103536-etin5i7y	24	18	leads	lead	VBZ
cord-103536-etin5i7y	24	19	to	to	IN
cord-103536-etin5i7y	24	20	the	the	DT
cord-103536-etin5i7y	24	21	release	release	NN
cord-103536-etin5i7y	24	22	of	of	IN
cord-103536-etin5i7y	24	23	virus	virus	NN
cord-103536-etin5i7y	24	24	-	-	HYPH
cord-103536-etin5i7y	24	25	like	like	JJ
cord-103536-etin5i7y	24	26	particles	particle	NNS
cord-103536-etin5i7y	24	27	(	(	-LRB-
cord-103536-etin5i7y	24	28	VLPs	vlp	NNS
cord-103536-etin5i7y	24	29	)	)	-RRB-
cord-103536-etin5i7y	24	30	.	.	.
cord-103536-etin5i7y	25	1	In	in	IN
cord-103536-etin5i7y	25	2	immature	immature	JJ
cord-103536-etin5i7y	25	3	viral	viral	JJ
cord-103536-etin5i7y	25	4	particles	particle	NNS
cord-103536-etin5i7y	25	5	,	,	,
cord-103536-etin5i7y	25	6	proteolytic	proteolytic	JJ
cord-103536-etin5i7y	25	7	processing	processing	NN
cord-103536-etin5i7y	25	8	generates	generate	VBZ
cord-103536-etin5i7y	25	9	several	several	JJ
cord-103536-etin5i7y	25	10	distinct	distinct	JJ
cord-103536-etin5i7y	25	11	protein	protein	NN
cord-103536-etin5i7y	25	12	products	product	NNS
cord-103536-etin5i7y	25	13	,	,	,
cord-103536-etin5i7y	25	14	including	include	VBG
cord-103536-etin5i7y	25	15	MA	MA	NNP
cord-103536-etin5i7y	25	16	(	(	-LRB-
cord-103536-etin5i7y	25	17	matrix	matrix	NN
cord-103536-etin5i7y	25	18	protein	protein	NN
cord-103536-etin5i7y	25	19	)	)	-RRB-
cord-103536-etin5i7y	25	20	,	,	,
cord-103536-etin5i7y	25	21	CA	CA	NNP
cord-103536-etin5i7y	25	22	(	(	-LRB-
cord-103536-etin5i7y	25	23	capsid	capsid	NN
cord-103536-etin5i7y	25	24	protein	protein	NN
cord-103536-etin5i7y	25	25	)	)	-RRB-
cord-103536-etin5i7y	25	26	and	and	CC
cord-103536-etin5i7y	25	27	NC	NC	NNP
cord-103536-etin5i7y	25	28	(	(	-LRB-
cord-103536-etin5i7y	25	29	nucleocapsid	nucleocapsid	NNP
cord-103536-etin5i7y	25	30	protein	protein	NNP
cord-103536-etin5i7y	25	31	)	)	-RRB-
cord-103536-etin5i7y	25	32	thus	thus	RB
cord-103536-etin5i7y	25	33	producing	produce	VBG
cord-103536-etin5i7y	25	34	mature	mature	JJ
cord-103536-etin5i7y	25	35	infectious	infectious	JJ
cord-103536-etin5i7y	25	36	virions	virion	NNS
cord-103536-etin5i7y	25	37	.	.	.
cord-103536-etin5i7y	26	1	Like	like	IN
cord-103536-etin5i7y	26	2	the	the	DT
cord-103536-etin5i7y	26	3	matrix	matrix	NN
cord-103536-etin5i7y	26	4	protein	protein	NN
cord-103536-etin5i7y	26	5	from	from	IN
cord-103536-etin5i7y	26	6	negative	negative	JJ
cord-103536-etin5i7y	26	7	strand	strand	NN
cord-103536-etin5i7y	26	8	RNA	RNA	NNP
cord-103536-etin5i7y	26	9	viruses	virus	NNS
cord-103536-etin5i7y	26	10	MA	MA	NNP
cord-103536-etin5i7y	26	11	is	be	VBZ
cord-103536-etin5i7y	26	12	associated	associate	VBN
cord-103536-etin5i7y	26	13	with	with	IN
cord-103536-etin5i7y	26	14	the	the	DT
cord-103536-etin5i7y	26	15	viral	viral	JJ
cord-103536-etin5i7y	26	16	membrane	membrane	NN
cord-103536-etin5i7y	26	17	and	and	CC
cord-103536-etin5i7y	26	18	thus	thus	RB
cord-103536-etin5i7y	26	19	performs	perform	VBZ
cord-103536-etin5i7y	26	20	essentially	essentially	RB
cord-103536-etin5i7y	26	21	the	the	DT
cord-103536-etin5i7y	26	22	same	same	JJ
cord-103536-etin5i7y	26	23	structural	structural	JJ
cord-103536-etin5i7y	26	24	function	function	NN
cord-103536-etin5i7y	26	25	[	[	-LRB-
cord-103536-etin5i7y	26	26	6	6	CD
cord-103536-etin5i7y	26	27	]	]	-RRB-
cord-103536-etin5i7y	26	28	.	.	.
cord-103536-etin5i7y	27	1	Lipid	lipid	NN
cord-103536-etin5i7y	27	2	rafts	raft	NNS
cord-103536-etin5i7y	27	3	are	be	VBP
cord-103536-etin5i7y	27	4	enriched	enrich	VBN
cord-103536-etin5i7y	27	5	in	in	IN
cord-103536-etin5i7y	27	6	cholesterol	cholesterol	NN
cord-103536-etin5i7y	27	7	and	and	CC
cord-103536-etin5i7y	27	8	sphingolipids	sphingolipid	NNS
cord-103536-etin5i7y	27	9	that	that	WDT
cord-103536-etin5i7y	27	10	can	can	MD
cord-103536-etin5i7y	27	11	selectively	selectively	RB
cord-103536-etin5i7y	27	12	incorporate	incorporate	VB
cord-103536-etin5i7y	27	13	or	or	CC
cord-103536-etin5i7y	27	14	exclude	exclude	VB
cord-103536-etin5i7y	27	15	proteins	protein	NNS
cord-103536-etin5i7y	27	16	and	and	CC
cord-103536-etin5i7y	27	17	have	have	VBP
cord-103536-etin5i7y	27	18	been	be	VBN
cord-103536-etin5i7y	27	19	first	first	RB
cord-103536-etin5i7y	27	20	implicated	implicate	VBN
cord-103536-etin5i7y	27	21	in	in	IN
cord-103536-etin5i7y	27	22	influenza	influenza	NN
cord-103536-etin5i7y	27	23	virus	virus	NN
cord-103536-etin5i7y	27	24	budding	bud	VBG
cord-103536-etin5i7y	27	25	[	[	-LRB-
cord-103536-etin5i7y	27	26	7	7	CD
cord-103536-etin5i7y	27	27	]	]	-RRB-
cord-103536-etin5i7y	27	28	.	.	.
cord-103536-etin5i7y	28	1	Subsequent	subsequent	JJ
cord-103536-etin5i7y	28	2	studies	study	NNS
cord-103536-etin5i7y	28	3	found	find	VBD
cord-103536-etin5i7y	28	4	the	the	DT
cord-103536-etin5i7y	28	5	same	same	JJ
cord-103536-etin5i7y	28	6	principle	principle	NN
cord-103536-etin5i7y	28	7	for	for	IN
cord-103536-etin5i7y	28	8	measles	measles	NN
cord-103536-etin5i7y	28	9	virus	virus	NN
cord-103536-etin5i7y	28	10	,	,	,
cord-103536-etin5i7y	28	11	HIV	HIV	NNP
cord-103536-etin5i7y	28	12	and	and	CC
cord-103536-etin5i7y	28	13	Ebola	Ebola	NNP
cord-103536-etin5i7y	28	14	virus	virus	NN
cord-103536-etin5i7y	28	15	.	.	.
cord-103536-etin5i7y	29	1	These	these	DT
cord-103536-etin5i7y	29	2	studies	study	NNS
cord-103536-etin5i7y	29	3	show	show	VBP
cord-103536-etin5i7y	29	4	that	that	IN
cord-103536-etin5i7y	29	5	lipid	lipid	NN
cord-103536-etin5i7y	29	6	rafts	raft	NNS
cord-103536-etin5i7y	29	7	concentrate	concentrate	VBP
cord-103536-etin5i7y	29	8	glycoproteins	glycoprotein	NNS
cord-103536-etin5i7y	29	9	and	and	CC
cord-103536-etin5i7y	29	10	matrix	matrix	NN
cord-103536-etin5i7y	29	11	proteins	protein	NNS
cord-103536-etin5i7y	29	12	thus	thus	RB
cord-103536-etin5i7y	29	13	establishing	establish	VBG
cord-103536-etin5i7y	29	14	platforms	platform	NNS
cord-103536-etin5i7y	29	15	for	for	IN
cord-103536-etin5i7y	29	16	efficient	efficient	JJ
cord-103536-etin5i7y	29	17	assembly	assembly	NN
cord-103536-etin5i7y	29	18	and	and	CC
cord-103536-etin5i7y	29	19	budding	bud	VBG
cord-103536-etin5i7y	29	20	[	[	-LRB-
cord-103536-etin5i7y	29	21	2	2	CD
cord-103536-etin5i7y	29	22	]	]	-RRB-
cord-103536-etin5i7y	29	23	.	.	.
cord-103536-etin5i7y	30	1	The	the	DT
cord-103536-etin5i7y	30	2	first	first	JJ
cord-103536-etin5i7y	30	3	evidence	evidence	NN
cord-103536-etin5i7y	30	4	for	for	IN
cord-103536-etin5i7y	30	5	the	the	DT
cord-103536-etin5i7y	30	6	involvement	involvement	NN
cord-103536-etin5i7y	30	7	of	of	IN
cord-103536-etin5i7y	30	8	specific	specific	JJ
cord-103536-etin5i7y	30	9	Gag	Gag	NNP
cord-103536-etin5i7y	30	10	domains	domain	NNS
cord-103536-etin5i7y	30	11	in	in	IN
cord-103536-etin5i7y	30	12	viral	viral	JJ
cord-103536-etin5i7y	30	13	budding	budding	NN
cord-103536-etin5i7y	30	14	came	come	VBD
cord-103536-etin5i7y	30	15	from	from	IN
cord-103536-etin5i7y	30	16	the	the	DT
cord-103536-etin5i7y	30	17	work	work	NN
cord-103536-etin5i7y	30	18	of	of	IN
cord-103536-etin5i7y	30	19	G€	G€	NNP
cord-103536-etin5i7y	30	20	ottlinger	ottlinger	NN
cord-103536-etin5i7y	30	21	and	and	CC
cord-103536-etin5i7y	30	22	colleagues	colleague	NNS
cord-103536-etin5i7y	30	23	who	who	WP
cord-103536-etin5i7y	30	24	reported	report	VBD
cord-103536-etin5i7y	30	25	that	that	IN
cord-103536-etin5i7y	30	26	a	a	DT
cord-103536-etin5i7y	30	27	deletion	deletion	NN
cord-103536-etin5i7y	30	28	of	of	IN
cord-103536-etin5i7y	30	29	the	the	DT
cord-103536-etin5i7y	30	30	C	C	NNP
cord-103536-etin5i7y	30	31	-	-	HYPH
cord-103536-etin5i7y	30	32	terminal	terminal	NN
cord-103536-etin5i7y	30	33	region	region	NN
cord-103536-etin5i7y	30	34	of	of	IN
cord-103536-etin5i7y	30	35	HIV	HIV	NNP
cord-103536-etin5i7y	30	36	Gag	Gag	NNP
cord-103536-etin5i7y	30	37	(	(	-LRB-
cord-103536-etin5i7y	30	38	p6	p6	NNP
cord-103536-etin5i7y	30	39	protein	protein	NN
cord-103536-etin5i7y	30	40	)	)	-RRB-
cord-103536-etin5i7y	30	41	caused	cause	VBD
cord-103536-etin5i7y	30	42	a	a	DT
cord-103536-etin5i7y	30	43	significant	significant	JJ
cord-103536-etin5i7y	30	44	defect	defect	NN
cord-103536-etin5i7y	30	45	in	in	IN
cord-103536-etin5i7y	30	46	virus	virus	NN
cord-103536-etin5i7y	30	47	particle	particle	NN
cord-103536-etin5i7y	30	48	release	release	NN
cord-103536-etin5i7y	30	49	[	[	-LRB-
cord-103536-etin5i7y	30	50	8	8	CD
cord-103536-etin5i7y	30	51	]	]	-RRB-
cord-103536-etin5i7y	30	52	.	.	.
cord-103536-etin5i7y	31	1	Electron	electron	NN
cord-103536-etin5i7y	31	2	microscopy	microscopy	NN
cord-103536-etin5i7y	31	3	studies	study	NNS
cord-103536-etin5i7y	31	4	revealed	reveal	VBD
cord-103536-etin5i7y	31	5	that	that	IN
cord-103536-etin5i7y	31	6	these	these	DT
cord-103536-etin5i7y	31	7	particles	particle	NNS
cord-103536-etin5i7y	31	8	failed	fail	VBD
cord-103536-etin5i7y	31	9	to	to	TO
cord-103536-etin5i7y	31	10	pinch	pinch	VB
cord-103536-etin5i7y	31	11	off	off	RP
cord-103536-etin5i7y	31	12	the	the	DT
cord-103536-etin5i7y	31	13	plasma	plasma	NN
cord-103536-etin5i7y	31	14	membrane	membrane	NN
cord-103536-etin5i7y	31	15	.	.	.
cord-103536-etin5i7y	32	1	Subsequent	subsequent	JJ
cord-103536-etin5i7y	32	2	studies	study	NNS
cord-103536-etin5i7y	32	3	then	then	RB
cord-103536-etin5i7y	32	4	identified	identify	VBD
cord-103536-etin5i7y	32	5	a	a	DT
cord-103536-etin5i7y	32	6	highly	highly	RB
cord-103536-etin5i7y	32	7	conserved	conserve	VBN
cord-103536-etin5i7y	32	8	Pro	pro	JJ
cord-103536-etin5i7y	32	9	-	-	JJ
cord-103536-etin5i7y	32	10	Thr	Thr	NNP
cord-103536-etin5i7y	32	11	-	-	HYPH
cord-103536-etin5i7y	32	12	Ala	Ala	NNP
cord-103536-etin5i7y	32	13	-	-	HYPH
cord-103536-etin5i7y	32	14	Pro	pro	JJ
cord-103536-etin5i7y	32	15	sequence	sequence	NN
cord-103536-etin5i7y	32	16	motif	motif	NN
cord-103536-etin5i7y	32	17	,	,	,
cord-103536-etin5i7y	32	18	termed	term	VBN
cord-103536-etin5i7y	32	19	late	late	JJ
cord-103536-etin5i7y	32	20	domain	domain	NN
cord-103536-etin5i7y	32	21	,	,	,
cord-103536-etin5i7y	32	22	as	as	IN
cord-103536-etin5i7y	32	23	playing	play	VBG
cord-103536-etin5i7y	32	24	a	a	DT
cord-103536-etin5i7y	32	25	crucial	crucial	JJ
cord-103536-etin5i7y	32	26	role	role	NN
cord-103536-etin5i7y	32	27	in	in	IN
cord-103536-etin5i7y	32	28	viral	viral	JJ
cord-103536-etin5i7y	32	29	budding	bud	VBG
cord-103536-etin5i7y	32	30	[	[	-LRB-
cord-103536-etin5i7y	32	31	9	9	CD
cord-103536-etin5i7y	32	32	]	]	-RRB-
cord-103536-etin5i7y	32	33	.	.	.
cord-103536-etin5i7y	33	1	Up	up	IN
cord-103536-etin5i7y	33	2	to	to	IN
cord-103536-etin5i7y	33	3	date	date	NN
cord-103536-etin5i7y	33	4	,	,	,
cord-103536-etin5i7y	33	5	several	several	JJ
cord-103536-etin5i7y	33	6	classes	class	NNS
cord-103536-etin5i7y	33	7	of	of	IN
cord-103536-etin5i7y	33	8	viral	viral	JJ
cord-103536-etin5i7y	33	9	late	late	JJ
cord-103536-etin5i7y	33	10	domains	domain	NNS
cord-103536-etin5i7y	33	11	have	have	VBP
cord-103536-etin5i7y	33	12	been	be	VBN
cord-103536-etin5i7y	33	13	described	describe	VBN
cord-103536-etin5i7y	33	14	,	,	,
cord-103536-etin5i7y	33	15	namely	namely	RB
cord-103536-etin5i7y	33	16	P(T	P(T	NNP
cord-103536-etin5i7y	33	17	/	/	SYM
cord-103536-etin5i7y	33	18	S)AP	S)AP	NNP
cord-103536-etin5i7y	33	19	,	,	,
cord-103536-etin5i7y	33	20	YXXL	YXXL	NNP
cord-103536-etin5i7y	33	21	LXXLF	LXXLF	NNP
cord-103536-etin5i7y	33	22	and	and	CC
cord-103536-etin5i7y	33	23	PPXY	PPXY	NNP
cord-103536-etin5i7y	33	24	.	.	.
cord-103536-etin5i7y	34	1	They	-PRON-	PRP
cord-103536-etin5i7y	34	2	are	be	VBP
cord-103536-etin5i7y	34	3	present	present	JJ
cord-103536-etin5i7y	34	4	alone	alone	RB
cord-103536-etin5i7y	34	5	or	or	CC
cord-103536-etin5i7y	34	6	in	in	IN
cord-103536-etin5i7y	34	7	different	different	JJ
cord-103536-etin5i7y	34	8	combinations	combination	NNS
cord-103536-etin5i7y	34	9	in	in	IN
cord-103536-etin5i7y	34	10	the	the	DT
cord-103536-etin5i7y	34	11	matrix	matrix	NN
cord-103536-etin5i7y	34	12	proteins	protein	NNS
cord-103536-etin5i7y	34	13	of	of	IN
cord-103536-etin5i7y	34	14	negative	negative	JJ
cord-103536-etin5i7y	34	15	-	-	HYPH
cord-103536-etin5i7y	34	16	strand	strand	NN
cord-103536-etin5i7y	34	17	RNA	RNA	NNP
cord-103536-etin5i7y	34	18	viruses	virus	NNS
cord-103536-etin5i7y	34	19	and	and	CC
cord-103536-etin5i7y	34	20	in	in	IN
cord-103536-etin5i7y	34	21	the	the	DT
cord-103536-etin5i7y	34	22	Gag	Gag	NNP
cord-103536-etin5i7y	34	23	proteins	protein	NNS
cord-103536-etin5i7y	34	24	of	of	IN
cord-103536-etin5i7y	34	25	retroviruses	retrovirus	NNS
cord-103536-etin5i7y	34	26	.	.	.
cord-103536-etin5i7y	35	1	In	in	IN
cord-103536-etin5i7y	35	2	several	several	JJ
cord-103536-etin5i7y	35	3	cases	case	NNS
cord-103536-etin5i7y	35	4	,	,	,
cord-103536-etin5i7y	35	5	viral	viral	JJ
cord-103536-etin5i7y	35	6	late	late	JJ
cord-103536-etin5i7y	35	7	domains	domain	NNS
cord-103536-etin5i7y	35	8	have	have	VBP
cord-103536-etin5i7y	35	9	been	be	VBN
cord-103536-etin5i7y	35	10	shown	show	VBN
cord-103536-etin5i7y	35	11	to	to	TO
cord-103536-etin5i7y	35	12	be	be	VB
cord-103536-etin5i7y	35	13	functionally	functionally	RB
cord-103536-etin5i7y	35	14	interchangeable	interchangeable	JJ
cord-103536-etin5i7y	35	15	,	,	,
cord-103536-etin5i7y	35	16	can	can	MD
cord-103536-etin5i7y	35	17	be	be	VB
cord-103536-etin5i7y	35	18	positioned	position	VBN
cord-103536-etin5i7y	35	19	at	at	IN
cord-103536-etin5i7y	35	20	various	various	JJ
cord-103536-etin5i7y	35	21	locations	location	NNS
cord-103536-etin5i7y	35	22	and	and	CC
cord-103536-etin5i7y	35	23	can	can	MD
cord-103536-etin5i7y	35	24	act	act	VB
cord-103536-etin5i7y	35	25	in	in	IN
cord-103536-etin5i7y	35	26	trans	trans	NNP
cord-103536-etin5i7y	35	27	[	[	-LRB-
cord-103536-etin5i7y	35	28	10	10	CD
cord-103536-etin5i7y	35	29	]	]	-RRB-
cord-103536-etin5i7y	35	30	.	.	.
cord-103536-etin5i7y	36	1	Recent	recent	JJ
cord-103536-etin5i7y	36	2	studies	study	NNS
cord-103536-etin5i7y	36	3	show	show	VBP
cord-103536-etin5i7y	36	4	that	that	IN
cord-103536-etin5i7y	36	5	the	the	DT
cord-103536-etin5i7y	36	6	late	late	JJ
cord-103536-etin5i7y	36	7	domains	domain	NNS
cord-103536-etin5i7y	36	8	serve	serve	VBP
cord-103536-etin5i7y	36	9	as	as	IN
cord-103536-etin5i7y	36	10	entry	entry	NN
cord-103536-etin5i7y	36	11	points	point	NNS
cord-103536-etin5i7y	36	12	into	into	IN
cord-103536-etin5i7y	36	13	the	the	DT
cord-103536-etin5i7y	36	14	vacuolar	vacuolar	NNP
cord-103536-etin5i7y	36	15	protein	protein	NN
cord-103536-etin5i7y	36	16	sorting	sorting	NN
cord-103536-etin5i7y	36	17	(	(	-LRB-
cord-103536-etin5i7y	36	18	Vps	Vps	NNP
cord-103536-etin5i7y	36	19	)	)	-RRB-
cord-103536-etin5i7y	36	20	pathway	pathway	NN
cord-103536-etin5i7y	36	21	and	and	CC
cord-103536-etin5i7y	36	22	connect	connect	VB
cord-103536-etin5i7y	36	23	matrix	matrix	NN
cord-103536-etin5i7y	36	24	proteins	protein	NNS
cord-103536-etin5i7y	36	25	or	or	CC
cord-103536-etin5i7y	36	26	Gag	gag	NN
cord-103536-etin5i7y	36	27	to	to	IN
cord-103536-etin5i7y	36	28	cellular	cellular	JJ
cord-103536-etin5i7y	36	29	factors	factor	NNS
cord-103536-etin5i7y	36	30	.	.	.
cord-103536-etin5i7y	37	1	The	the	DT
cord-103536-etin5i7y	37	2	Vps	Vps	NNP
cord-103536-etin5i7y	37	3	machinery	machinery	NN
cord-103536-etin5i7y	37	4	was	be	VBD
cord-103536-etin5i7y	37	5	first	first	RB
cord-103536-etin5i7y	37	6	described	describe	VBN
cord-103536-etin5i7y	37	7	in	in	IN
cord-103536-etin5i7y	37	8	yeast	yeast	NN
cord-103536-etin5i7y	37	9	and	and	CC
cord-103536-etin5i7y	37	10	implicated	implicate	VBN
cord-103536-etin5i7y	37	11	in	in	IN
cord-103536-etin5i7y	37	12	membrane	membrane	NN
cord-103536-etin5i7y	37	13	protein	protein	NN
cord-103536-etin5i7y	37	14	trafficking	traffic	VBG
cord-103536-etin5i7y	37	15	from	from	IN
cord-103536-etin5i7y	37	16	the	the	DT
cord-103536-etin5i7y	37	17	Golgi	Golgi	NNP
cord-103536-etin5i7y	37	18	and	and	CC
cord-103536-etin5i7y	37	19	plasma	plasma	NN
cord-103536-etin5i7y	37	20	membrane	membrane	NN
cord-103536-etin5i7y	37	21	via	via	IN
cord-103536-etin5i7y	37	22	the	the	DT
cord-103536-etin5i7y	37	23	endosomal	endosomal	NNP
cord-103536-etin5i7y	37	24	system	system	NN
cord-103536-etin5i7y	37	25	to	to	IN
cord-103536-etin5i7y	37	26	the	the	DT
cord-103536-etin5i7y	37	27	lysosome	lysosome	NN
cord-103536-etin5i7y	37	28	for	for	IN
cord-103536-etin5i7y	37	29	degradation	degradation	NN
cord-103536-etin5i7y	37	30	(	(	-LRB-
cord-103536-etin5i7y	37	31	for	for	IN
cord-103536-etin5i7y	37	32	review	review	NN
cord-103536-etin5i7y	37	33	,	,	,
cord-103536-etin5i7y	37	34	see	see	VB
cord-103536-etin5i7y	37	35	[	[	-LRB-
cord-103536-etin5i7y	37	36	11	11	CD
cord-103536-etin5i7y	37	37	]	]	-RRB-
cord-103536-etin5i7y	37	38	)	)	-RRB-
cord-103536-etin5i7y	37	39	.	.	.
cord-103536-etin5i7y	38	1	Mutation	mutation	NN
cord-103536-etin5i7y	38	2	of	of	IN
cord-103536-etin5i7y	38	3	any	any	DT
cord-103536-etin5i7y	38	4	of	of	IN
cord-103536-etin5i7y	38	5	the	the	DT
cord-103536-etin5i7y	38	6	17	17	CD
cord-103536-etin5i7y	38	7	different	different	JJ
cord-103536-etin5i7y	38	8	yeast	yeast	NN
cord-103536-etin5i7y	38	9	Vps	Vps	NNP
cord-103536-etin5i7y	38	10	proteins	protein	NNS
cord-103536-etin5i7y	38	11	leads	lead	VBZ
cord-103536-etin5i7y	38	12	to	to	IN
cord-103536-etin5i7y	38	13	the	the	DT
cord-103536-etin5i7y	38	14	formation	formation	NN
cord-103536-etin5i7y	38	15	of	of	IN
cord-103536-etin5i7y	38	16	enlarged	enlarged	JJ
cord-103536-etin5i7y	38	17	endosomal	endosomal	NNP
cord-103536-etin5i7y	38	18	membrane	membrane	NN
cord-103536-etin5i7y	38	19	compartments	compartment	NNS
cord-103536-etin5i7y	38	20	that	that	WDT
cord-103536-etin5i7y	38	21	can	can	MD
cord-103536-etin5i7y	38	22	not	not	RB
cord-103536-etin5i7y	38	23	mature	mature	VB
cord-103536-etin5i7y	38	24	into	into	IN
cord-103536-etin5i7y	38	25	multi	multi	JJ
cord-103536-etin5i7y	38	26	vesicular	vesicular	JJ
cord-103536-etin5i7y	38	27	bodies	body	NNS
cord-103536-etin5i7y	38	28	(	(	-LRB-
cord-103536-etin5i7y	38	29	MVB	mvb	NN
cord-103536-etin5i7y	38	30	;	;	:
cord-103536-etin5i7y	38	31	class	class	NN
cord-103536-etin5i7y	38	32	E	e	NN
cord-103536-etin5i7y	38	33	compartment	compartment	NN
cord-103536-etin5i7y	38	34	)	)	-RRB-
cord-103536-etin5i7y	38	35	.	.	.
cord-103536-etin5i7y	39	1	Most	Most	JJS
cord-103536-etin5i7y	39	2	of	of	IN
cord-103536-etin5i7y	39	3	the	the	DT
cord-103536-etin5i7y	39	4	class	class	NN
cord-103536-etin5i7y	39	5	E	e	NN
cord-103536-etin5i7y	39	6	Vps	Vps	NNP
cord-103536-etin5i7y	39	7	proteins	protein	NNS
cord-103536-etin5i7y	39	8	exist	exist	VBP
cord-103536-etin5i7y	39	9	as	as	IN
cord-103536-etin5i7y	39	10	soluble	soluble	JJ
cord-103536-etin5i7y	39	11	proteins	protein	NNS
cord-103536-etin5i7y	39	12	or	or	CC
cord-103536-etin5i7y	39	13	small	small	JJ
cord-103536-etin5i7y	39	14	subcomplexes	subcomplexe	NNS
cord-103536-etin5i7y	39	15	that	that	WDT
cord-103536-etin5i7y	39	16	are	be	VBP
cord-103536-etin5i7y	39	17	sequentially	sequentially	RB
cord-103536-etin5i7y	39	18	recruited	recruit	VBN
cord-103536-etin5i7y	39	19	to	to	IN
cord-103536-etin5i7y	39	20	the	the	DT
cord-103536-etin5i7y	39	21	site	site	NN
cord-103536-etin5i7y	39	22	of	of	IN
cord-103536-etin5i7y	39	23	MVB	MVB	NNP
cord-103536-etin5i7y	39	24	formation	formation	NN
cord-103536-etin5i7y	39	25	.	.	.
cord-103536-etin5i7y	40	1	Initial	initial	JJ
cord-103536-etin5i7y	40	2	recognition	recognition	NN
cord-103536-etin5i7y	40	3	of	of	IN
cord-103536-etin5i7y	40	4	the	the	DT
cord-103536-etin5i7y	40	5	cargo	cargo	NN
cord-103536-etin5i7y	40	6	involves	involve	VBZ
cord-103536-etin5i7y	40	7	class	class	NN
cord-103536-etin5i7y	40	8	E	e	NN
cord-103536-etin5i7y	40	9	proteins	protein	NNS
cord-103536-etin5i7y	40	10	Hrs	Hrs	NNP
cord-103536-etin5i7y	40	11	(	(	-LRB-
cord-103536-etin5i7y	40	12	Vps27p	Vps27p	NNP
cord-103536-etin5i7y	40	13	)	)	-RRB-
cord-103536-etin5i7y	40	14	,	,	,
cord-103536-etin5i7y	40	15	Stam	Stam	NNP
cord-103536-etin5i7y	40	16	,	,	,
cord-103536-etin5i7y	40	17	Eps15	Eps15	NNP
cord-103536-etin5i7y	40	18	(	(	-LRB-
cord-103536-etin5i7y	40	19	Ede1p	Ede1p	NNP
cord-103536-etin5i7y	40	20	)	)	-RRB-
cord-103536-etin5i7y	40	21	and	and	CC
cord-103536-etin5i7y	40	22	clathrin	clathrin	NNP
cord-103536-etin5i7y	40	23	.	.	.
cord-103536-etin5i7y	41	1	This	this	DT
cord-103536-etin5i7y	41	2	leads	lead	VBZ
cord-103536-etin5i7y	41	3	to	to	IN
cord-103536-etin5i7y	41	4	the	the	DT
cord-103536-etin5i7y	41	5	recruitment	recruitment	NN
cord-103536-etin5i7y	41	6	of	of	IN
cord-103536-etin5i7y	41	7	ESCRT-1	ESCRT-1	NNP
cord-103536-etin5i7y	41	8	(	(	-LRB-
cord-103536-etin5i7y	41	9	endosome	endosome	NN
cord-103536-etin5i7y	41	10	-	-	HYPH
cord-103536-etin5i7y	41	11	associated	associate	VBN
cord-103536-etin5i7y	41	12	complexes	complex	NNS
cord-103536-etin5i7y	41	13	required	require	VBN
cord-103536-etin5i7y	41	14	for	for	IN
cord-103536-etin5i7y	41	15	transport	transport	NN
cord-103536-etin5i7y	41	16	)	)	-RRB-
cord-103536-etin5i7y	41	17	,	,	,
cord-103536-etin5i7y	41	18	composed	compose	VBN
cord-103536-etin5i7y	41	19	of	of	IN
cord-103536-etin5i7y	41	20	Vps23p	Vps23p	NNP
cord-103536-etin5i7y	41	21	,	,	,
cord-103536-etin5i7y	41	22	Vps28p	Vps28p	NNP
cord-103536-etin5i7y	41	23	and	and	CC
cord-103536-etin5i7y	41	24	Vps37p	Vps37p	NNP
cord-103536-etin5i7y	41	25	to	to	IN
cord-103536-etin5i7y	41	26	the	the	DT
cord-103536-etin5i7y	41	27	endosomal	endosomal	NNP
cord-103536-etin5i7y	41	28	membrane	membrane	NN
cord-103536-etin5i7y	41	29	where	where	WRB
cord-103536-etin5i7y	41	30	it	-PRON-	PRP
cord-103536-etin5i7y	41	31	recognizes	recognize	VBZ
cord-103536-etin5i7y	41	32	ubiquitinated	ubiquitinated	JJ
cord-103536-etin5i7y	41	33	cargo	cargo	NN
cord-103536-etin5i7y	41	34	.	.	.
cord-103536-etin5i7y	42	1	ESCRT	ESCRT	NNP
cord-103536-etin5i7y	42	2	-	-	HYPH
cord-103536-etin5i7y	42	3	I	-PRON-	PRP
cord-103536-etin5i7y	42	4	cargo	cargo	NN
cord-103536-etin5i7y	42	5	recognition	recognition	NN
cord-103536-etin5i7y	42	6	then	then	RB
cord-103536-etin5i7y	42	7	induces	induce	VBZ
cord-103536-etin5i7y	42	8	the	the	DT
cord-103536-etin5i7y	42	9	formation	formation	NN
cord-103536-etin5i7y	42	10	of	of	IN
cord-103536-etin5i7y	42	11	ESCRT	ESCRT	NNP
cord-103536-etin5i7y	42	12	-	-	HYPH
cord-103536-etin5i7y	42	13	II	II	NNP
cord-103536-etin5i7y	42	14	(	(	-LRB-
cord-103536-etin5i7y	42	15	Vps22p	Vps22p	NNP
cord-103536-etin5i7y	42	16	,	,	,
cord-103536-etin5i7y	42	17	Vps25p	vps25p	JJ
cord-103536-etin5i7y	42	18	and	and	CC
cord-103536-etin5i7y	42	19	Vps36p	Vps36p	NNP
cord-103536-etin5i7y	42	20	)	)	-RRB-
cord-103536-etin5i7y	42	21	and	and	CC
cord-103536-etin5i7y	42	22	that	that	IN
cord-103536-etin5i7y	42	23	in	in	IN
cord-103536-etin5i7y	42	24	turn	turn	NN
cord-103536-etin5i7y	42	25	activates	activate	VBZ
cord-103536-etin5i7y	42	26	the	the	DT
cord-103536-etin5i7y	42	27	assembly	assembly	NN
cord-103536-etin5i7y	42	28	of	of	IN
cord-103536-etin5i7y	42	29	ESCRT	ESCRT	NNP
cord-103536-etin5i7y	42	30	-	-	HYPH
cord-103536-etin5i7y	42	31	III	III	NNP
cord-103536-etin5i7y	42	32	multi	multi	JJ
cord-103536-etin5i7y	42	33	-	-	JJ
cord-103536-etin5i7y	42	34	protein	protein	JJ
cord-103536-etin5i7y	42	35	complexes	complex	NNS
cord-103536-etin5i7y	42	36	.	.	.
cord-103536-etin5i7y	43	1	Finally	finally	RB
cord-103536-etin5i7y	43	2	,	,	,
cord-103536-etin5i7y	43	3	another	another	DT
cord-103536-etin5i7y	43	4	class	class	NN
cord-103536-etin5i7y	43	5	E	e	NN
cord-103536-etin5i7y	43	6	Vps	Vps	NNP
cord-103536-etin5i7y	43	7	protein	protein	NN
cord-103536-etin5i7y	43	8	,	,	,
cord-103536-etin5i7y	43	9	Vps4	Vps4	VBZ
cord-103536-etin5i7y	43	10	an	an	DT
cord-103536-etin5i7y	43	11	AAA	aaa	NN
cord-103536-etin5i7y	43	12	-	-	HYPH
cord-103536-etin5i7y	43	13	type	type	NN
cord-103536-etin5i7y	43	14	ATPase	ATPase	NNP
cord-103536-etin5i7y	43	15	,	,	,
cord-103536-etin5i7y	43	16	has	have	VBZ
cord-103536-etin5i7y	43	17	been	be	VBN
cord-103536-etin5i7y	43	18	implicated	implicate	VBN
cord-103536-etin5i7y	43	19	in	in	IN
cord-103536-etin5i7y	43	20	the	the	DT
cord-103536-etin5i7y	43	21	disassembly	disassembly	NN
cord-103536-etin5i7y	43	22	of	of	IN
cord-103536-etin5i7y	43	23	ESCRT	ESCRT	NNP
cord-103536-etin5i7y	43	24	-	-	HYPH
cord-103536-etin5i7y	43	25	III	III	NNP
cord-103536-etin5i7y	43	26	a	a	DT
cord-103536-etin5i7y	43	27	necessary	necessary	JJ
cord-103536-etin5i7y	43	28	step	step	NN
cord-103536-etin5i7y	43	29	for	for	IN
cord-103536-etin5i7y	43	30	MVB	MVB	NNP
cord-103536-etin5i7y	43	31	formation	formation	NN
cord-103536-etin5i7y	43	32	(	(	-LRB-
cord-103536-etin5i7y	43	33	reviewed	review	VBN
cord-103536-etin5i7y	43	34	by	by	IN
cord-103536-etin5i7y	43	35	Katzmann	Katzmann	NNP
cord-103536-etin5i7y	43	36	et	et	NNP
cord-103536-etin5i7y	43	37	al	al	NNP
cord-103536-etin5i7y	43	38	.	.	.
cord-103536-etin5i7y	44	1	[	[	-LRB-
cord-103536-etin5i7y	44	2	11	11	CD
cord-103536-etin5i7y	44	3	]	]	-RRB-
cord-103536-etin5i7y	44	4	)	)	-RRB-
cord-103536-etin5i7y	44	5	.	.	.
cord-103536-etin5i7y	45	1	Although	although	IN
cord-103536-etin5i7y	45	2	the	the	DT
cord-103536-etin5i7y	45	3	mammalian	mammalian	JJ
cord-103536-etin5i7y	45	4	system	system	NN
cord-103536-etin5i7y	45	5	is	be	VBZ
cord-103536-etin5i7y	45	6	more	more	RBR
cord-103536-etin5i7y	45	7	complex	complex	JJ
cord-103536-etin5i7y	45	8	the	the	DT
cord-103536-etin5i7y	45	9	framework	framework	NN
cord-103536-etin5i7y	45	10	is	be	VBZ
cord-103536-etin5i7y	45	11	similar	similar	JJ
cord-103536-etin5i7y	45	12	.	.	.
cord-103536-etin5i7y	46	1	Most	Most	JJS
cord-103536-etin5i7y	46	2	of	of	IN
cord-103536-etin5i7y	46	3	the	the	DT
cord-103536-etin5i7y	46	4	components	component	NNS
cord-103536-etin5i7y	46	5	have	have	VBP
cord-103536-etin5i7y	46	6	now	now	RB
cord-103536-etin5i7y	46	7	been	be	VBN
cord-103536-etin5i7y	46	8	described	describe	VBN
cord-103536-etin5i7y	46	9	and	and	CC
cord-103536-etin5i7y	46	10	their	-PRON-	PRP$
cord-103536-etin5i7y	46	11	interactions	interaction	NNS
cord-103536-etin5i7y	46	12	have	have	VBP
cord-103536-etin5i7y	46	13	been	be	VBN
cord-103536-etin5i7y	46	14	mapped	map	VBN
cord-103536-etin5i7y	46	15	[	[	-LRB-
cord-103536-etin5i7y	46	16	12	12	CD
cord-103536-etin5i7y	46	17	,	,	,
cord-103536-etin5i7y	46	18	13	13	CD
cord-103536-etin5i7y	46	19	]	]	-RRB-
cord-103536-etin5i7y	46	20	.	.	.
cord-103536-etin5i7y	47	1	There	there	EX
cord-103536-etin5i7y	47	2	are	be	VBP
cord-103536-etin5i7y	47	3	two	two	CD
cord-103536-etin5i7y	47	4	human	human	JJ
cord-103536-etin5i7y	47	5	class	class	NN
cord-103536-etin5i7y	47	6	E	E	NNP
cord-103536-etin5i7y	47	7	Vps	Vps	NNP
cord-103536-etin5i7y	47	8	proteins	protein	NNS
cord-103536-etin5i7y	47	9	identified	identify	VBD
cord-103536-etin5i7y	47	10	that	that	IN
cord-103536-etin5i7y	47	11	recognize	recognize	VBP
cord-103536-etin5i7y	47	12	late	late	JJ
cord-103536-etin5i7y	47	13	domains	domain	NNS
cord-103536-etin5i7y	47	14	,	,	,
cord-103536-etin5i7y	47	15	namely	namely	RB
cord-103536-etin5i7y	47	16	tsg101	tsg101	NNP
cord-103536-etin5i7y	47	17	(	(	-LRB-
cord-103536-etin5i7y	47	18	via	via	IN
cord-103536-etin5i7y	47	19	P(T	P(T	NNP
cord-103536-etin5i7y	47	20	/	/	SYM
cord-103536-etin5i7y	47	21	S)AP	S)AP	NNP
cord-103536-etin5i7y	47	22	)	)	-RRB-
cord-103536-etin5i7y	47	23	,	,	,
cord-103536-etin5i7y	47	24	which	which	WDT
cord-103536-etin5i7y	47	25	is	be	VBZ
cord-103536-etin5i7y	47	26	part	part	NN
cord-103536-etin5i7y	47	27	of	of	IN
cord-103536-etin5i7y	47	28	ESCRT	ESCRT	NNP
cord-103536-etin5i7y	48	1	-I	-I	NNP
cord-103536-etin5i7y	48	2	and	and	CC
cord-103536-etin5i7y	48	3	AIP-1/	aip-1/	RB
cord-103536-etin5i7y	48	4	ALIX	ALIX	NNP
cord-103536-etin5i7y	49	1	(	(	-LRB-
cord-103536-etin5i7y	49	2	via	via	IN
cord-103536-etin5i7y	49	3	LXXLF	LXXLF	NNP
cord-103536-etin5i7y	49	4	and	and	CC
cord-103536-etin5i7y	49	5	YXXL	YXXL	NNP
cord-103536-etin5i7y	49	6	)	)	-RRB-
cord-103536-etin5i7y	49	7	which	which	WDT
cord-103536-etin5i7y	49	8	in	in	IN
cord-103536-etin5i7y	49	9	turn	turn	NN
cord-103536-etin5i7y	49	10	interacts	interact	VBZ
cord-103536-etin5i7y	49	11	with	with	IN
cord-103536-etin5i7y	49	12	Tsg101	tsg101	ADD
cord-103536-etin5i7y	49	13	and	and	CC
cord-103536-etin5i7y	49	14	CHMP4	CHMP4	NNS
cord-103536-etin5i7y	49	15	proteins	protein	NNS
cord-103536-etin5i7y	49	16	(	(	-LRB-
cord-103536-etin5i7y	49	17	ESCRT	ESCRT	NNP
cord-103536-etin5i7y	49	18	-	-	HYPH
cord-103536-etin5i7y	49	19	III	III	NNP
cord-103536-etin5i7y	49	20	)	)	-RRB-
cord-103536-etin5i7y	49	21	,	,	,
cord-103536-etin5i7y	49	22	thus	thus	RB
cord-103536-etin5i7y	49	23	providing	provide	VBG
cord-103536-etin5i7y	49	24	a	a	DT
cord-103536-etin5i7y	49	25	link	link	NN
cord-103536-etin5i7y	49	26	between	between	IN
cord-103536-etin5i7y	49	27	ESCRT	ESCRT	NNP
cord-103536-etin5i7y	49	28	-	-	HYPH
cord-103536-etin5i7y	49	29	I	I	NNP
cord-103536-etin5i7y	49	30	and	and	CC
cord-103536-etin5i7y	49	31	ESCRT	ESCRT	NNP
cord-103536-etin5i7y	49	32	-	-	HYPH
cord-103536-etin5i7y	49	33	III	III	NNP
cord-103536-etin5i7y	49	34	in	in	IN
cord-103536-etin5i7y	49	35	retroviral	retroviral	NN
cord-103536-etin5i7y	49	36	budding	bud	VBG
cord-103536-etin5i7y	49	37	[	[	-LRB-
cord-103536-etin5i7y	49	38	12	12	CD
cord-103536-etin5i7y	49	39	,	,	,
cord-103536-etin5i7y	49	40	13	13	CD
cord-103536-etin5i7y	49	41	]	]	-RRB-
cord-103536-etin5i7y	49	42	.	.	.
cord-103536-etin5i7y	50	1	It	-PRON-	PRP
cord-103536-etin5i7y	50	2	is	be	VBZ
cord-103536-etin5i7y	50	3	now	now	RB
cord-103536-etin5i7y	50	4	recognized	recognize	VBN
cord-103536-etin5i7y	50	5	that	that	IN
cord-103536-etin5i7y	50	6	late	late	JJ
cord-103536-etin5i7y	50	7	domain	domain	NN
cord-103536-etin5i7y	50	8	interactions	interaction	NNS
cord-103536-etin5i7y	50	9	with	with	IN
cord-103536-etin5i7y	50	10	cellular	cellular	JJ
cord-103536-etin5i7y	50	11	factors	factor	NNS
cord-103536-etin5i7y	50	12	most	most	RBS
cord-103536-etin5i7y	50	13	likely	likely	RB
cord-103536-etin5i7y	50	14	recruit	recruit	VBP
cord-103536-etin5i7y	50	15	the	the	DT
cord-103536-etin5i7y	50	16	whole	whole	JJ
cord-103536-etin5i7y	50	17	Vps	Vps	NNP
cord-103536-etin5i7y	50	18	machinery	machinery	NN
cord-103536-etin5i7y	50	19	to	to	IN
cord-103536-etin5i7y	50	20	the	the	DT
cord-103536-etin5i7y	50	21	site	site	NN
cord-103536-etin5i7y	50	22	of	of	IN
cord-103536-etin5i7y	50	23	budding	bud	VBG
cord-103536-etin5i7y	50	24	.	.	.
cord-103536-etin5i7y	51	1	The	the	DT
cord-103536-etin5i7y	51	2	PPXY	PPXY	NNP
cord-103536-etin5i7y	51	3	motif	motif	NN
cord-103536-etin5i7y	51	4	,	,	,
cord-103536-etin5i7y	51	5	the	the	DT
cord-103536-etin5i7y	51	6	fourth	fourth	JJ
cord-103536-etin5i7y	51	7	identified	identify	VBN
cord-103536-etin5i7y	51	8	late	late	JJ
cord-103536-etin5i7y	51	9	domain	domain	NN
cord-103536-etin5i7y	51	10	has	have	VBZ
cord-103536-etin5i7y	51	11	been	be	VBN
cord-103536-etin5i7y	51	12	found	find	VBN
cord-103536-etin5i7y	51	13	in	in	IN
cord-103536-etin5i7y	51	14	some	some	DT
cord-103536-etin5i7y	51	15	retroviruses	retrovirus	NNS
cord-103536-etin5i7y	51	16	,	,	,
cord-103536-etin5i7y	51	17	in	in	IN
cord-103536-etin5i7y	51	18	rhabdoviruses	rhabdovirus	NNS
cord-103536-etin5i7y	51	19	and	and	CC
cord-103536-etin5i7y	51	20	filoviruses	filovirus	NNS
cord-103536-etin5i7y	51	21	(	(	-LRB-
cord-103536-etin5i7y	51	22	[	[	-LRB-
cord-103536-etin5i7y	51	23	10	10	CD
cord-103536-etin5i7y	51	24	]	]	-RRB-
cord-103536-etin5i7y	51	25	and	and	CC
cord-103536-etin5i7y	51	26	references	reference	NNS
cord-103536-etin5i7y	51	27	therein	therein	RB
cord-103536-etin5i7y	51	28	)	)	-RRB-
cord-103536-etin5i7y	51	29	.	.	.
cord-103536-etin5i7y	52	1	The	the	DT
cord-103536-etin5i7y	52	2	PPXY	PPXY	NNP
cord-103536-etin5i7y	52	3	motif	motif	NN
cord-103536-etin5i7y	52	4	mediates	mediate	VBZ
cord-103536-etin5i7y	52	5	interactions	interaction	NNS
cord-103536-etin5i7y	52	6	with	with	IN
cord-103536-etin5i7y	52	7	proteins	protein	NNS
cord-103536-etin5i7y	52	8	that	that	WDT
cord-103536-etin5i7y	52	9	contain	contain	VBP
cord-103536-etin5i7y	52	10	WW	WW	NNP
cord-103536-etin5i7y	52	11	domains	domain	NNS
cord-103536-etin5i7y	52	12	,	,	,
cord-103536-etin5i7y	52	13	such	such	JJ
cord-103536-etin5i7y	52	14	as	as	IN
cord-103536-etin5i7y	52	15	Nedd4	nedd4	JJ
cord-103536-etin5i7y	52	16	family	family	NN
cord-103536-etin5i7y	52	17	ubiquitin	ubiquitin	NN
cord-103536-etin5i7y	52	18	ligases	ligase	NNS
cord-103536-etin5i7y	52	19	(	(	-LRB-
cord-103536-etin5i7y	52	20	E3	E3	NNP
cord-103536-etin5i7y	52	21	enzyme	enzyme	NN
cord-103536-etin5i7y	52	22	)	)	-RRB-
cord-103536-etin5i7y	52	23	,	,	,
cord-103536-etin5i7y	52	24	which	which	WDT
cord-103536-etin5i7y	52	25	are	be	VBP
cord-103536-etin5i7y	52	26	part	part	NN
cord-103536-etin5i7y	52	27	of	of	IN
cord-103536-etin5i7y	52	28	an	an	DT
cord-103536-etin5i7y	52	29	enzymatic	enzymatic	JJ
cord-103536-etin5i7y	52	30	cascade	cascade	NN
cord-103536-etin5i7y	52	31	in	in	IN
cord-103536-etin5i7y	52	32	which	which	WDT
cord-103536-etin5i7y	52	33	single	single	JJ
cord-103536-etin5i7y	52	34	ubiquitin	ubiquitin	NN
cord-103536-etin5i7y	52	35	moieties	moiety	NNS
cord-103536-etin5i7y	52	36	are	be	VBP
cord-103536-etin5i7y	52	37	transferred	transfer	VBN
cord-103536-etin5i7y	52	38	to	to	IN
cord-103536-etin5i7y	52	39	lysine	lysine	NN
cord-103536-etin5i7y	52	40	residues	residue	NNS
cord-103536-etin5i7y	52	41	on	on	IN
cord-103536-etin5i7y	52	42	the	the	DT
cord-103536-etin5i7y	52	43	protein	protein	NN
cord-103536-etin5i7y	52	44	substrate	substrate	NN
cord-103536-etin5i7y	52	45	.	.	.
cord-103536-etin5i7y	53	1	Monoubiquitination	monoubiquitination	NN
cord-103536-etin5i7y	53	2	of	of	IN
cord-103536-etin5i7y	53	3	matrix	matrix	NN
cord-103536-etin5i7y	53	4	proteins	protein	NNS
cord-103536-etin5i7y	53	5	is	be	VBZ
cord-103536-etin5i7y	53	6	consistent	consistent	JJ
cord-103536-etin5i7y	53	7	with	with	IN
cord-103536-etin5i7y	53	8	recent	recent	JJ
cord-103536-etin5i7y	53	9	findings	finding	NNS
cord-103536-etin5i7y	53	10	that	that	WDT
cord-103536-etin5i7y	53	11	show	show	VBP
cord-103536-etin5i7y	53	12	that	that	IN
cord-103536-etin5i7y	53	13	ubiquitin	ubiquitin	NN
cord-103536-etin5i7y	53	14	plays	play	VBZ
cord-103536-etin5i7y	53	15	a	a	DT
cord-103536-etin5i7y	53	16	role	role	NN
cord-103536-etin5i7y	53	17	in	in	IN
cord-103536-etin5i7y	53	18	retrovirus	retrovirus	NN
cord-103536-etin5i7y	53	19	budding	bud	VBG
cord-103536-etin5i7y	53	20	[	[	-LRB-
cord-103536-etin5i7y	53	21	14	14	CD
cord-103536-etin5i7y	53	22	,	,	,
cord-103536-etin5i7y	53	23	15	15	CD
cord-103536-etin5i7y	53	24	]	]	-RRB-
cord-103536-etin5i7y	53	25	and	and	CC
cord-103536-etin5i7y	53	26	that	that	IN
cord-103536-etin5i7y	53	27	Ebola	Ebola	NNP
cord-103536-etin5i7y	53	28	virus	virus	NN
cord-103536-etin5i7y	53	29	VP40	VP40	NNP
cord-103536-etin5i7y	53	30	can	can	MD
cord-103536-etin5i7y	53	31	be	be	VB
cord-103536-etin5i7y	53	32	ubiquitinated	ubiquitinate	VBN
cord-103536-etin5i7y	53	33	in	in	IN
cord-103536-etin5i7y	53	34	vitro	vitro	FW
cord-103536-etin5i7y	53	35	[	[	-LRB-
cord-103536-etin5i7y	53	36	16	16	CD
cord-103536-etin5i7y	53	37	]	]	-RRB-
cord-103536-etin5i7y	53	38	.	.	.
cord-103536-etin5i7y	54	1	Ubiquitination	Ubiquitination	NNP
cord-103536-etin5i7y	54	2	may	may	MD
cord-103536-etin5i7y	54	3	thus	thus	RB
cord-103536-etin5i7y	54	4	help	help	VB
cord-103536-etin5i7y	54	5	to	to	TO
cord-103536-etin5i7y	54	6	recruit	recruit	VB
cord-103536-etin5i7y	54	7	the	the	DT
cord-103536-etin5i7y	54	8	class	class	NN
cord-103536-etin5i7y	54	9	E	E	NNP
cord-103536-etin5i7y	54	10	Vps	Vps	NNP
cord-103536-etin5i7y	54	11	components	component	NNS
cord-103536-etin5i7y	54	12	in	in	IN
cord-103536-etin5i7y	54	13	a	a	DT
cord-103536-etin5i7y	54	14	similar	similar	JJ
cord-103536-etin5i7y	54	15	way	way	NN
cord-103536-etin5i7y	54	16	as	as	IN
cord-103536-etin5i7y	54	17	sorting	sorting	NN
cord-103536-etin5i7y	54	18	of	of	IN
cord-103536-etin5i7y	54	19	plasma	plasma	NN
cord-103536-etin5i7y	54	20	membrane	membrane	NN
cord-103536-etin5i7y	54	21	receptors	receptor	NNS
cord-103536-etin5i7y	54	22	requires	require	VBZ
cord-103536-etin5i7y	54	23	monoubiquitination	monoubiquitination	NN
cord-103536-etin5i7y	54	24	[	[	-LRB-
cord-103536-etin5i7y	54	25	11	11	CD
cord-103536-etin5i7y	54	26	]	]	-RRB-
cord-103536-etin5i7y	54	27	.	.	.
cord-103536-etin5i7y	55	1	In	in	IN
cord-103536-etin5i7y	55	2	addition	addition	NN
cord-103536-etin5i7y	55	3	,	,	,
cord-103536-etin5i7y	55	4	Nedd4	Nedd4	NNP
cord-103536-etin5i7y	55	5	,	,	,
cord-103536-etin5i7y	55	6	which	which	WDT
cord-103536-etin5i7y	55	7	can	can	MD
cord-103536-etin5i7y	55	8	be	be	VB
cord-103536-etin5i7y	55	9	also	also	RB
cord-103536-etin5i7y	55	10	found	find	VBN
cord-103536-etin5i7y	55	11	in	in	IN
cord-103536-etin5i7y	55	12	lipid	lipid	NN
cord-103536-etin5i7y	55	13	rafts	raft	NNS
cord-103536-etin5i7y	55	14	[	[	-LRB-
cord-103536-etin5i7y	55	15	17	17	CD
cord-103536-etin5i7y	55	16	]	]	-RRB-
cord-103536-etin5i7y	55	17	,	,	,
cord-103536-etin5i7y	55	18	has	have	VBZ
cord-103536-etin5i7y	55	19	been	be	VBN
cord-103536-etin5i7y	55	20	linked	link	VBN
cord-103536-etin5i7y	55	21	genetically	genetically	RB
cord-103536-etin5i7y	55	22	to	to	IN
cord-103536-etin5i7y	55	23	ESCRT	ESCRT	NNP
cord-103536-etin5i7y	55	24	-	-	HYPH
cord-103536-etin5i7y	55	25	III	III	NNP
cord-103536-etin5i7y	55	26	in	in	IN
cord-103536-etin5i7y	55	27	yeast	yeast	NN
cord-103536-etin5i7y	55	28	[	[	-LRB-
cord-103536-etin5i7y	55	29	18	18	CD
cord-103536-etin5i7y	55	30	]	]	-RRB-
cord-103536-etin5i7y	55	31	.	.	.
cord-103536-etin5i7y	56	1	Finally	finally	RB
cord-103536-etin5i7y	56	2	,	,	,
cord-103536-etin5i7y	56	3	lipids	lipid	NNS
cord-103536-etin5i7y	56	4	and	and	CC
cord-103536-etin5i7y	56	5	lipid	lipid	NN
cord-103536-etin5i7y	56	6	modifying	modify	VBG
cord-103536-etin5i7y	56	7	enzymes	enzyme	NNS
cord-103536-etin5i7y	56	8	,	,	,
cord-103536-etin5i7y	56	9	such	such	JJ
cord-103536-etin5i7y	56	10	as	as	IN
cord-103536-etin5i7y	56	11	endophilins	endophilin	NNS
cord-103536-etin5i7y	56	12	that	that	WDT
cord-103536-etin5i7y	56	13	interact	interact	VBP
cord-103536-etin5i7y	56	14	with	with	IN
cord-103536-etin5i7y	57	1	AIP1	AIP1	NNP
cord-103536-etin5i7y	57	2	/	/	SYM
cord-103536-etin5i7y	57	3	ALIX	ALIX	NNP
cord-103536-etin5i7y	57	4	[	[	-LRB-
cord-103536-etin5i7y	57	5	19	19	CD
cord-103536-etin5i7y	57	6	]	]	-RRB-
cord-103536-etin5i7y	57	7	might	may	MD
cord-103536-etin5i7y	57	8	play	play	VB
cord-103536-etin5i7y	57	9	an	an	DT
cord-103536-etin5i7y	57	10	important	important	JJ
cord-103536-etin5i7y	57	11	role	role	NN
cord-103536-etin5i7y	57	12	in	in	IN
cord-103536-etin5i7y	57	13	viral	viral	JJ
cord-103536-etin5i7y	57	14	budding	bud	VBG
cord-103536-etin5i7y	57	15	[	[	-LRB-
cord-103536-etin5i7y	57	16	20	20	CD
cord-103536-etin5i7y	57	17	]	]	-RRB-
cord-103536-etin5i7y	57	18	.	.	.
cord-103536-etin5i7y	58	1	Up	up	IN
cord-103536-etin5i7y	58	2	to	to	IN
cord-103536-etin5i7y	58	3	now	now	RB
cord-103536-etin5i7y	58	4	not	not	RB
cord-103536-etin5i7y	58	5	all	all	RB
cord-103536-etin5i7y	58	6	enveloped	envelop	VBN
cord-103536-etin5i7y	58	7	viruses	virus	NNS
cord-103536-etin5i7y	58	8	contain	contain	VBP
cord-103536-etin5i7y	58	9	any	any	DT
cord-103536-etin5i7y	58	10	of	of	IN
cord-103536-etin5i7y	58	11	the	the	DT
cord-103536-etin5i7y	58	12	known	know	VBN
cord-103536-etin5i7y	58	13	late	late	JJ
cord-103536-etin5i7y	58	14	domain	domain	NN
cord-103536-etin5i7y	58	15	sequences	sequence	NNS
cord-103536-etin5i7y	58	16	which	which	WDT
cord-103536-etin5i7y	58	17	could	could	MD
cord-103536-etin5i7y	58	18	serve	serve	VB
cord-103536-etin5i7y	58	19	as	as	IN
cord-103536-etin5i7y	58	20	entry	entry	NN
cord-103536-etin5i7y	58	21	points	point	NNS
cord-103536-etin5i7y	58	22	into	into	IN
cord-103536-etin5i7y	58	23	the	the	DT
cord-103536-etin5i7y	58	24	Vps	Vps	NNP
cord-103536-etin5i7y	58	25	machinery	machinery	NN
cord-103536-etin5i7y	58	26	;	;	:
cord-103536-etin5i7y	58	27	however	however	RB
cord-103536-etin5i7y	58	28	it	-PRON-	PRP
cord-103536-etin5i7y	58	29	is	be	VBZ
cord-103536-etin5i7y	58	30	likely	likely	JJ
cord-103536-etin5i7y	58	31	that	that	IN
cord-103536-etin5i7y	58	32	they	-PRON-	PRP
cord-103536-etin5i7y	58	33	might	may	MD
cord-103536-etin5i7y	58	34	yet	yet	RB
cord-103536-etin5i7y	58	35	use	use	VB
cord-103536-etin5i7y	58	36	other	other	JJ
cord-103536-etin5i7y	58	37	short	short	JJ
cord-103536-etin5i7y	58	38	sequence	sequence	NN
cord-103536-etin5i7y	58	39	elements	element	NNS
cord-103536-etin5i7y	58	40	which	which	WDT
cord-103536-etin5i7y	58	41	facilitate	facilitate	VBP
cord-103536-etin5i7y	58	42	Vps	Vps	NNP
cord-103536-etin5i7y	58	43	recruitment	recruitment	NN
cord-103536-etin5i7y	58	44	.	.	.
cord-103536-etin5i7y	59	1	In	in	IN
cord-103536-etin5i7y	59	2	addition	addition	NN
cord-103536-etin5i7y	59	3	this	this	DT
cord-103536-etin5i7y	59	4	function	function	NN
cord-103536-etin5i7y	59	5	may	may	MD
cord-103536-etin5i7y	59	6	not	not	RB
cord-103536-etin5i7y	59	7	reside	reside	VB
cord-103536-etin5i7y	59	8	within	within	IN
cord-103536-etin5i7y	59	9	the	the	DT
cord-103536-etin5i7y	59	10	matrix	matrix	NN
cord-103536-etin5i7y	59	11	protein	protein	NN
cord-103536-etin5i7y	59	12	.	.	.
cord-103536-etin5i7y	60	1	To	to	IN
cord-103536-etin5i7y	60	2	date	date	NN
cord-103536-etin5i7y	60	3	there	there	EX
cord-103536-etin5i7y	60	4	is	be	VBZ
cord-103536-etin5i7y	60	5	still	still	RB
cord-103536-etin5i7y	60	6	limited	limit	VBN
cord-103536-etin5i7y	60	7	structural	structural	JJ
cord-103536-etin5i7y	60	8	information	information	NN
cord-103536-etin5i7y	60	9	on	on	IN
cord-103536-etin5i7y	60	10	viral	viral	JJ
cord-103536-etin5i7y	60	11	matrix	matrix	NN
cord-103536-etin5i7y	60	12	proteins	protein	NNS
cord-103536-etin5i7y	60	13	as	as	IN
cord-103536-etin5i7y	60	14	only	only	RB
cord-103536-etin5i7y	60	15	four	four	CD
cord-103536-etin5i7y	60	16	different	different	JJ
cord-103536-etin5i7y	60	17	matrix	matrix	NN
cord-103536-etin5i7y	60	18	protein	protein	NN
cord-103536-etin5i7y	60	19	structures	structure	NNS
cord-103536-etin5i7y	60	20	have	have	VBP
cord-103536-etin5i7y	60	21	been	be	VBN
cord-103536-etin5i7y	60	22	solved	solve	VBN
cord-103536-etin5i7y	60	23	,	,	,
cord-103536-etin5i7y	60	24	including	include	VBG
cord-103536-etin5i7y	60	25	VP40	VP40	NNP
cord-103536-etin5i7y	60	26	from	from	IN
cord-103536-etin5i7y	60	27	Ebola	Ebola	NNP
cord-103536-etin5i7y	60	28	virus	virus	NN
cord-103536-etin5i7y	60	29	,	,	,
cord-103536-etin5i7y	60	30	M	M	NNP
cord-103536-etin5i7y	60	31	from	from	IN
cord-103536-etin5i7y	60	32	VSV	VSV	NNP
cord-103536-etin5i7y	60	33	,	,	,
cord-103536-etin5i7y	60	34	a	a	DT
cord-103536-etin5i7y	60	35	fragment	fragment	NN
cord-103536-etin5i7y	60	36	of	of	IN
cord-103536-etin5i7y	60	37	M1	M1	NNP
cord-103536-etin5i7y	60	38	from	from	IN
cord-103536-etin5i7y	60	39	influenza	influenza	NN
cord-103536-etin5i7y	60	40	virus	virus	NN
cord-103536-etin5i7y	60	41	and	and	CC
cord-103536-etin5i7y	60	42	a	a	DT
cord-103536-etin5i7y	60	43	number	number	NN
cord-103536-etin5i7y	60	44	of	of	IN
cord-103536-etin5i7y	60	45	retroviral	retroviral	JJ
cord-103536-etin5i7y	60	46	matrix	matrix	NN
cord-103536-etin5i7y	60	47	proteins	protein	NNS
cord-103536-etin5i7y	60	48	.	.	.
cord-103536-etin5i7y	61	1	The	the	DT
cord-103536-etin5i7y	61	2	Ebola	Ebola	NNP
cord-103536-etin5i7y	61	3	virus	virus	NN
cord-103536-etin5i7y	61	4	matrix	matrix	NN
cord-103536-etin5i7y	61	5	protein	protein	NN
cord-103536-etin5i7y	62	1	VP40	VP40	NNP
cord-103536-etin5i7y	62	2	is	be	VBZ
cord-103536-etin5i7y	62	3	an	an	DT
cord-103536-etin5i7y	62	4	elongated	elongated	JJ
cord-103536-etin5i7y	62	5	,	,	,
cord-103536-etin5i7y	62	6	two	two	CD
cord-103536-etin5i7y	62	7	-	-	HYPH
cord-103536-etin5i7y	62	8	domain	domain	NN
cord-103536-etin5i7y	62	9	monomeric	monomeric	JJ
cord-103536-etin5i7y	62	10	assembly	assembly	NN
cord-103536-etin5i7y	62	11	,	,	,
cord-103536-etin5i7y	62	12	composed	compose	VBN
cord-103536-etin5i7y	62	13	of	of	IN
cord-103536-etin5i7y	62	14	two	two	CD
cord-103536-etin5i7y	62	15	structurally	structurally	RB
cord-103536-etin5i7y	62	16	related	relate	VBN
cord-103536-etin5i7y	62	17	b	b	NN
cord-103536-etin5i7y	62	18	-	-	HYPH
cord-103536-etin5i7y	62	19	sandwich	sandwich	NN
cord-103536-etin5i7y	62	20	domains	domain	NNS
cord-103536-etin5i7y	62	21	,	,	,
cord-103536-etin5i7y	62	22	which	which	WDT
cord-103536-etin5i7y	62	23	are	be	VBP
cord-103536-etin5i7y	62	24	connected	connect	VBN
cord-103536-etin5i7y	62	25	by	by	IN
cord-103536-etin5i7y	62	26	a	a	DT
cord-103536-etin5i7y	62	27	flexible	flexible	JJ
cord-103536-etin5i7y	62	28	linker	linker	NN
cord-103536-etin5i7y	62	29	(	(	-LRB-
cord-103536-etin5i7y	62	30	Fig	Fig	NNP
cord-103536-etin5i7y	62	31	.	.	.
cord-103536-etin5i7y	62	32	1(a	1(a	CD
cord-103536-etin5i7y	62	33	)	)	-RRB-
cord-103536-etin5i7y	62	34	)	)	-RRB-
cord-103536-etin5i7y	62	35	.	.	.
cord-103536-etin5i7y	63	1	Indeed	indeed	RB
cord-103536-etin5i7y	63	2	the	the	DT
cord-103536-etin5i7y	63	3	unique	unique	JJ
cord-103536-etin5i7y	63	4	fold	fold	NN
cord-103536-etin5i7y	63	5	of	of	IN
cord-103536-etin5i7y	63	6	both	both	DT
cord-103536-etin5i7y	63	7	domains	domain	NNS
cord-103536-etin5i7y	63	8	suggests	suggest	VBZ
cord-103536-etin5i7y	63	9	that	that	IN
cord-103536-etin5i7y	63	10	the	the	DT
cord-103536-etin5i7y	63	11	two	two	CD
cord-103536-etin5i7y	63	12	domains	domain	NNS
cord-103536-etin5i7y	63	13	probably	probably	RB
cord-103536-etin5i7y	63	14	arose	arise	VBD
cord-103536-etin5i7y	63	15	from	from	IN
cord-103536-etin5i7y	63	16	a	a	DT
cord-103536-etin5i7y	63	17	common	common	JJ
cord-103536-etin5i7y	63	18	ancestor	ancestor	NN
cord-103536-etin5i7y	63	19	by	by	IN
cord-103536-etin5i7y	63	20	gene	gene	NN
cord-103536-etin5i7y	63	21	duplication	duplication	NN
cord-103536-etin5i7y	63	22	[	[	-LRB-
cord-103536-etin5i7y	63	23	21	21	CD
cord-103536-etin5i7y	63	24	]	]	-RRB-
cord-103536-etin5i7y	63	25	.	.	.
cord-103536-etin5i7y	64	1	Early	early	JJ
cord-103536-etin5i7y	64	2	work	work	NN
cord-103536-etin5i7y	64	3	showed	show	VBD
cord-103536-etin5i7y	64	4	that	that	IN
cord-103536-etin5i7y	64	5	this	this	DT
cord-103536-etin5i7y	64	6	conformation	conformation	NN
cord-103536-etin5i7y	64	7	of	of	IN
cord-103536-etin5i7y	64	8	VP40	VP40	NNP
cord-103536-etin5i7y	64	9	is	be	VBZ
cord-103536-etin5i7y	64	10	metastable	metastable	JJ
cord-103536-etin5i7y	64	11	,	,	,
cord-103536-etin5i7y	64	12	which	which	WDT
cord-103536-etin5i7y	64	13	allows	allow	VBZ
cord-103536-etin5i7y	64	14	an	an	DT
cord-103536-etin5i7y	64	15	easy	easy	JJ
cord-103536-etin5i7y	64	16	transition	transition	NN
cord-103536-etin5i7y	64	17	into	into	IN
cord-103536-etin5i7y	64	18	oligomeric	oligomeric	JJ
cord-103536-etin5i7y	64	19	ring	ring	NN
cord-103536-etin5i7y	64	20	-	-	HYPH
cord-103536-etin5i7y	64	21	like	like	JJ
cord-103536-etin5i7y	64	22	structures	structure	NNS
cord-103536-etin5i7y	64	23	in	in	IN
cord-103536-etin5i7y	64	24	vitro	vitro	FW
cord-103536-etin5i7y	64	25	[	[	-LRB-
cord-103536-etin5i7y	64	26	22	22	CD
cord-103536-etin5i7y	64	27	,	,	,
cord-103536-etin5i7y	64	28	23	23	CD
cord-103536-etin5i7y	64	29	]	]	-RRB-
cord-103536-etin5i7y	64	30	.	.	.
cord-103536-etin5i7y	65	1	The	the	DT
cord-103536-etin5i7y	65	2	ring	ring	NN
cord-103536-etin5i7y	65	3	-	-	HYPH
cord-103536-etin5i7y	65	4	structures	structure	NNS
cord-103536-etin5i7y	65	5	are	be	VBP
cord-103536-etin5i7y	65	6	either	either	CC
cord-103536-etin5i7y	65	7	octamers	octamer	NNS
cord-103536-etin5i7y	65	8	or	or	CC
cord-103536-etin5i7y	65	9	hexamers	hexamer	NNS
cord-103536-etin5i7y	65	10	[	[	-LRB-
cord-103536-etin5i7y	65	11	24	24	CD
cord-103536-etin5i7y	65	12	]	]	-RRB-
cord-103536-etin5i7y	66	1	(	(	-LRB-
cord-103536-etin5i7y	66	2	Figs	fig	NNS
cord-103536-etin5i7y	66	3	.	.	.
cord-103536-etin5i7y	66	4	1(b	1(b	CD
cord-103536-etin5i7y	66	5	)	)	-RRB-
cord-103536-etin5i7y	66	6	and	and	CC
cord-103536-etin5i7y	66	7	(	(	-LRB-
cord-103536-etin5i7y	66	8	c	c	NN
cord-103536-etin5i7y	66	9	)	)	-RRB-
cord-103536-etin5i7y	66	10	)	)	-RRB-
cord-103536-etin5i7y	66	11	.	.	.
cord-103536-etin5i7y	67	1	In	in	IN
cord-103536-etin5i7y	67	2	both	both	DT
cord-103536-etin5i7y	67	3	cases	case	NNS
cord-103536-etin5i7y	67	4	,	,	,
cord-103536-etin5i7y	67	5	the	the	DT
cord-103536-etin5i7y	67	6	Nterminal	Nterminal	NNP
cord-103536-etin5i7y	67	7	domain	domain	NN
cord-103536-etin5i7y	67	8	of	of	IN
cord-103536-etin5i7y	67	9	VP40	VP40	NNP
cord-103536-etin5i7y	67	10	constitutes	constitute	VBZ
cord-103536-etin5i7y	67	11	the	the	DT
cord-103536-etin5i7y	67	12	oligomerisation	oligomerisation	NN
cord-103536-etin5i7y	67	13	domain	domain	NN
cord-103536-etin5i7y	67	14	,	,	,
cord-103536-etin5i7y	67	15	which	which	WDT
cord-103536-etin5i7y	67	16	forms	form	VBZ
cord-103536-etin5i7y	67	17	an	an	DT
cord-103536-etin5i7y	67	18	anti	anti	JJ
cord-103536-etin5i7y	67	19	-	-	JJ
cord-103536-etin5i7y	67	20	parallel	parallel	JJ
cord-103536-etin5i7y	67	21	dimer	dimer	NN
cord-103536-etin5i7y	67	22	and	and	CC
cord-103536-etin5i7y	67	23	is	be	VBZ
cord-103536-etin5i7y	67	24	the	the	DT
cord-103536-etin5i7y	67	25	building	building	NN
cord-103536-etin5i7y	67	26	block	block	NN
cord-103536-etin5i7y	67	27	for	for	IN
cord-103536-etin5i7y	67	28	oligomerisation	oligomerisation	NN
cord-103536-etin5i7y	67	29	[	[	-LRB-
cord-103536-etin5i7y	67	30	23	23	CD
cord-103536-etin5i7y	67	31	,	,	,
cord-103536-etin5i7y	67	32	25	25	CD
cord-103536-etin5i7y	67	33	]	]	-RRB-
cord-103536-etin5i7y	67	34	.	.	.
cord-103536-etin5i7y	68	1	The	the	DT
cord-103536-etin5i7y	68	2	Cterminal	Cterminal	NNP
cord-103536-etin5i7y	68	3	domains	domain	NNS
cord-103536-etin5i7y	68	4	are	be	VBP
cord-103536-etin5i7y	68	5	flexibly	flexibly	RB
cord-103536-etin5i7y	68	6	attached	attach	VBN
cord-103536-etin5i7y	68	7	to	to	IN
cord-103536-etin5i7y	68	8	the	the	DT
cord-103536-etin5i7y	68	9	rings	ring	NNS
cord-103536-etin5i7y	68	10	and	and	CC
cord-103536-etin5i7y	68	11	mediate	mediate	VB
cord-103536-etin5i7y	68	12	membrane	membrane	NNP
cord-103536-etin5i7y	68	13	association	association	NN
cord-103536-etin5i7y	68	14	in	in	IN
cord-103536-etin5i7y	68	15	vitro	vitro	FW
cord-103536-etin5i7y	68	16	and	and	CC
cord-103536-etin5i7y	68	17	in	in	IN
cord-103536-etin5i7y	68	18	vivo	vivo	NNP
cord-103536-etin5i7y	68	19	[	[	-LRB-
cord-103536-etin5i7y	68	20	5	5	CD
cord-103536-etin5i7y	68	21	,	,	,
cord-103536-etin5i7y	68	22	22	22	CD
cord-103536-etin5i7y	68	23	,	,	,
cord-103536-etin5i7y	68	24	23	23	CD
cord-103536-etin5i7y	68	25	]	]	-RRB-
cord-103536-etin5i7y	68	26	(	(	-LRB-
cord-103536-etin5i7y	68	27	Figs	fig	NNS
cord-103536-etin5i7y	68	28	.	.	.
cord-103536-etin5i7y	68	29	1(b	1(b	CD
cord-103536-etin5i7y	68	30	)	)	-RRB-
cord-103536-etin5i7y	68	31	and	and	CC
cord-103536-etin5i7y	68	32	(	(	-LRB-
cord-103536-etin5i7y	68	33	c	c	NN
cord-103536-etin5i7y	68	34	)	)	-RRB-
cord-103536-etin5i7y	68	35	)	)	-RRB-
cord-103536-etin5i7y	68	36	.	.	.
cord-103536-etin5i7y	69	1	The	the	DT
cord-103536-etin5i7y	69	2	octamer	octamer	NN
cord-103536-etin5i7y	69	3	was	be	VBD
cord-103536-etin5i7y	69	4	found	find	VBN
cord-103536-etin5i7y	69	5	to	to	TO
cord-103536-etin5i7y	69	6	bind	bind	VB
cord-103536-etin5i7y	69	7	single	single	JJ
cord-103536-etin5i7y	69	8	stranded	strand	VBN
cord-103536-etin5i7y	69	9	RNA	RNA	NNP
cord-103536-etin5i7y	69	10	at	at	IN
cord-103536-etin5i7y	69	11	the	the	DT
cord-103536-etin5i7y	69	12	dimer	dimer	NN
cord-103536-etin5i7y	69	13	-	-	HYPH
cord-103536-etin5i7y	69	14	dimer	dimer	NN
cord-103536-etin5i7y	69	15	interface	interface	NN
cord-103536-etin5i7y	69	16	having	have	VBG
cord-103536-etin5i7y	69	17	the	the	DT
cord-103536-etin5i7y	69	18	sequence	sequence	NN
cord-103536-etin5i7y	69	19	5	5	CD
cord-103536-etin5i7y	69	20	0	0	CD
cord-103536-etin5i7y	69	21	-UGA-3	-uga-3	CD
cord-103536-etin5i7y	69	22	0	0	CD
cord-103536-etin5i7y	70	1	(	(	-LRB-
cord-103536-etin5i7y	70	2	Fig	Fig	NNP
cord-103536-etin5i7y	70	3	.	.	.
cord-103536-etin5i7y	70	4	1(b	1(b	CD
cord-103536-etin5i7y	70	5	)	)	-RRB-
cord-103536-etin5i7y	70	6	)	)	-RRB-
cord-103536-etin5i7y	70	7	.	.	.
cord-103536-etin5i7y	71	1	RNA	RNA	NNP
cord-103536-etin5i7y	71	2	binding	binding	NN
cord-103536-etin5i7y	71	3	creates	create	VBZ
cord-103536-etin5i7y	71	4	a	a	DT
cord-103536-etin5i7y	71	5	new	new	JJ
cord-103536-etin5i7y	71	6	dimer	dimer	NN
cord-103536-etin5i7y	71	7	-	-	HYPH
cord-103536-etin5i7y	71	8	dimer	dimer	NN
cord-103536-etin5i7y	71	9	interface	interface	NN
cord-103536-etin5i7y	71	10	and	and	CC
cord-103536-etin5i7y	71	11	its	-PRON-	PRP$
cord-103536-etin5i7y	71	12	binding	binding	NN
cord-103536-etin5i7y	71	13	stabilizes	stabilize	VBZ
cord-103536-etin5i7y	71	14	the	the	DT
cord-103536-etin5i7y	71	15	protein	protein	NN
cord-103536-etin5i7y	71	16	-	-	HYPH
cord-103536-etin5i7y	71	17	protein	protein	NN
cord-103536-etin5i7y	71	18	interaction	interaction	NN
cord-103536-etin5i7y	71	19	generating	generate	VBG
cord-103536-etin5i7y	71	20	the	the	DT
cord-103536-etin5i7y	71	21	octamers	octamer	NNS
cord-103536-etin5i7y	71	22	[	[	-LRB-
cord-103536-etin5i7y	71	23	25	25	CD
cord-103536-etin5i7y	71	24	]	]	-RRB-
cord-103536-etin5i7y	71	25	.	.	.
cord-103536-etin5i7y	72	1	Based	base	VBN
cord-103536-etin5i7y	72	2	on	on	IN
cord-103536-etin5i7y	72	3	the	the	DT
cord-103536-etin5i7y	72	4	crystal	crystal	JJ
cord-103536-etin5i7y	72	5	structure	structure	NN
cord-103536-etin5i7y	72	6	of	of	IN
cord-103536-etin5i7y	72	7	the	the	DT
cord-103536-etin5i7y	72	8	octamer	octamer	NNP
cord-103536-etin5i7y	72	9	,	,	,
cord-103536-etin5i7y	72	10	the	the	DT
cord-103536-etin5i7y	72	11	complete	complete	JJ
cord-103536-etin5i7y	72	12	N	n	CD
cord-103536-etin5i7y	72	13	-	-	HYPH
cord-103536-etin5i7y	72	14	terminal	terminal	NN
cord-103536-etin5i7y	72	15	segment	segment	NN
cord-103536-etin5i7y	72	16	from	from	IN
cord-103536-etin5i7y	72	17	residues	residue	NNS
cord-103536-etin5i7y	72	18	1	1	CD
cord-103536-etin5i7y	72	19	to	to	IN
cord-103536-etin5i7y	72	20	68	68	CD
cord-103536-etin5i7y	72	21	has	have	VBZ
cord-103536-etin5i7y	72	22	to	to	TO
cord-103536-etin5i7y	72	23	unfold	unfold	VB
cord-103536-etin5i7y	72	24	in	in	IN
cord-103536-etin5i7y	72	25	order	order	NN
cord-103536-etin5i7y	72	26	to	to	TO
cord-103536-etin5i7y	72	27	create	create	VB
cord-103536-etin5i7y	72	28	the	the	DT
cord-103536-etin5i7y	72	29	new	new	JJ
cord-103536-etin5i7y	72	30	ssRNA	ssrna	RB
cord-103536-etin5i7y	72	31	-	-	HYPH
cord-103536-etin5i7y	72	32	binding	bind	VBG
cord-103536-etin5i7y	72	33	interface	interface	NN
cord-103536-etin5i7y	72	34	.	.	.
cord-103536-etin5i7y	73	1	Interestingly	interestingly	RB
cord-103536-etin5i7y	73	2	recent	recent	JJ
cord-103536-etin5i7y	73	3	studies	study	NNS
cord-103536-etin5i7y	73	4	suggest	suggest	VBP
cord-103536-etin5i7y	73	5	that	that	IN
cord-103536-etin5i7y	73	6	the	the	DT
cord-103536-etin5i7y	73	7	SDS	SDS	NNP
cord-103536-etin5i7y	73	8	resistant	resistant	JJ
cord-103536-etin5i7y	73	9	octamer	octamer	NN
cord-103536-etin5i7y	73	10	is	be	VBZ
cord-103536-etin5i7y	73	11	present	present	JJ
cord-103536-etin5i7y	73	12	in	in	IN
cord-103536-etin5i7y	73	13	Ebola	Ebola	NNP
cord-103536-etin5i7y	73	14	VLPs	vlp	NNS
cord-103536-etin5i7y	73	15	and	and	CC
cord-103536-etin5i7y	73	16	in	in	IN
cord-103536-etin5i7y	73	17	virus	virus	NN
cord-103536-etin5i7y	73	18	particles	particle	NNS
cord-103536-etin5i7y	73	19	[	[	-LRB-
cord-103536-etin5i7y	73	20	26	26	CD
cord-103536-etin5i7y	73	21	]	]	-RRB-
cord-103536-etin5i7y	73	22	in	in	IN
cord-103536-etin5i7y	73	23	contrast	contrast	NN
cord-103536-etin5i7y	73	24	to	to	IN
cord-103536-etin5i7y	73	25	our	-PRON-	PRP$
cord-103536-etin5i7y	73	26	previous	previous	JJ
cord-103536-etin5i7y	73	27	finding	finding	NN
cord-103536-etin5i7y	73	28	which	which	WDT
cord-103536-etin5i7y	73	29	confirmed	confirm	VBD
cord-103536-etin5i7y	73	30	the	the	DT
cord-103536-etin5i7y	73	31	presence	presence	NN
cord-103536-etin5i7y	73	32	of	of	IN
cord-103536-etin5i7y	73	33	RNA	RNA	NNP
cord-103536-etin5i7y	73	34	containing	contain	VBG
cord-103536-etin5i7y	73	35	octamers	octamers	NNP
cord-103536-etin5i7y	73	36	only	only	RB
cord-103536-etin5i7y	73	37	in	in	IN
cord-103536-etin5i7y	73	38	infected	infected	JJ
cord-103536-etin5i7y	73	39	cells	cell	NNS
cord-103536-etin5i7y	73	40	but	but	CC
cord-103536-etin5i7y	73	41	not	not	RB
cord-103536-etin5i7y	73	42	in	in	IN
cord-103536-etin5i7y	73	43	virus	virus	NN
cord-103536-etin5i7y	73	44	particles	particle	NNS
cord-103536-etin5i7y	73	45	[	[	-LRB-
cord-103536-etin5i7y	73	46	25	25	CD
cord-103536-etin5i7y	73	47	]	]	-RRB-
cord-103536-etin5i7y	73	48	.	.	.
cord-103536-etin5i7y	74	1	A	a	DT
cord-103536-etin5i7y	74	2	role	role	NN
cord-103536-etin5i7y	74	3	for	for	IN
cord-103536-etin5i7y	74	4	the	the	DT
cord-103536-etin5i7y	74	5	ring	ring	NN
cord-103536-etin5i7y	74	6	structures	structure	NNS
cord-103536-etin5i7y	74	7	in	in	IN
cord-103536-etin5i7y	74	8	assembly	assembly	NN
cord-103536-etin5i7y	74	9	and	and	CC
cord-103536-etin5i7y	74	10	budding	budding	NN
cord-103536-etin5i7y	74	11	is	be	VBZ
cord-103536-etin5i7y	74	12	also	also	RB
cord-103536-etin5i7y	74	13	evident	evident	JJ
cord-103536-etin5i7y	74	14	from	from	IN
cord-103536-etin5i7y	74	15	the	the	DT
cord-103536-etin5i7y	74	16	fact	fact	NN
cord-103536-etin5i7y	74	17	that	that	IN
cord-103536-etin5i7y	74	18	only	only	RB
cord-103536-etin5i7y	74	19	oligomeric	oligomeric	JJ
cord-103536-etin5i7y	74	20	VP40	VP40	NNP
cord-103536-etin5i7y	74	21	interacted	interact	VBD
cord-103536-etin5i7y	74	22	with	with	IN
cord-103536-etin5i7y	74	23	WW3	WW3	NNP
cord-103536-etin5i7y	74	24	from	from	IN
cord-103536-etin5i7y	74	25	human	human	JJ
cord-103536-etin5i7y	74	26	Nedd4	Nedd4	NNP
cord-103536-etin5i7y	75	1	in	in	IN
cord-103536-etin5i7y	75	2	vitro	vitro	FW
cord-103536-etin5i7y	75	3	via	via	IN
cord-103536-etin5i7y	75	4	its	-PRON-	PRP$
cord-103536-etin5i7y	75	5	N	n	CD
cord-103536-etin5i7y	75	6	-	-	HYPH
cord-103536-etin5i7y	75	7	terminal	terminal	NN
cord-103536-etin5i7y	75	8	PPXY	PPXY	NNP
cord-103536-etin5i7y	75	9	motif	motif	NN
cord-103536-etin5i7y	75	10	[	[	-LRB-
cord-103536-etin5i7y	75	11	27	27	CD
cord-103536-etin5i7y	75	12	]	]	-RRB-
cord-103536-etin5i7y	75	13	,	,	,
cord-103536-etin5i7y	75	14	an	an	DT
cord-103536-etin5i7y	75	15	interaction	interaction	NN
cord-103536-etin5i7y	75	16	which	which	WDT
cord-103536-etin5i7y	75	17	is	be	VBZ
cord-103536-etin5i7y	75	18	important	important	JJ
cord-103536-etin5i7y	75	19	in	in	IN
cord-103536-etin5i7y	75	20	vivo	vivo	NNP
cord-103536-etin5i7y	75	21	[	[	-LRB-
cord-103536-etin5i7y	75	22	28	28	CD
cord-103536-etin5i7y	75	23	]	]	-RRB-
cord-103536-etin5i7y	75	24	.	.	.
cord-103536-etin5i7y	76	1	A	a	DT
cord-103536-etin5i7y	76	2	number	number	NN
cord-103536-etin5i7y	76	3	of	of	IN
cord-103536-etin5i7y	76	4	studies	study	NNS
cord-103536-etin5i7y	76	5	also	also	RB
cord-103536-etin5i7y	76	6	showed	show	VBD
cord-103536-etin5i7y	76	7	the	the	DT
cord-103536-etin5i7y	76	8	importance	importance	NN
cord-103536-etin5i7y	76	9	of	of	IN
cord-103536-etin5i7y	76	10	the	the	DT
cord-103536-etin5i7y	76	11	PTAP	PTAP	NNP
cord-103536-etin5i7y	76	12	motif	motif	NN
cord-103536-etin5i7y	76	13	present	present	JJ
cord-103536-etin5i7y	76	14	at	at	IN
cord-103536-etin5i7y	76	15	the	the	DT
cord-103536-etin5i7y	76	16	N	n	CD
cord-103536-etin5i7y	76	17	-	-	HYPH
cord-103536-etin5i7y	76	18	terminus	terminus	NN
cord-103536-etin5i7y	76	19	for	for	IN
cord-103536-etin5i7y	76	20	budding	bud	VBG
cord-103536-etin5i7y	76	21	[	[	-LRB-
cord-103536-etin5i7y	76	22	29	29	CD
cord-103536-etin5i7y	76	23	,	,	,
cord-103536-etin5i7y	76	24	30	30	CD
cord-103536-etin5i7y	76	25	]	]	-RRB-
cord-103536-etin5i7y	76	26	.	.	.
cord-103536-etin5i7y	77	1	This	this	DT
cord-103536-etin5i7y	77	2	motif	motif	NN
cord-103536-etin5i7y	77	3	binds	bind	VBZ
cord-103536-etin5i7y	77	4	to	to	IN
cord-103536-etin5i7y	77	5	the	the	DT
cord-103536-etin5i7y	77	6	UEV	UEV	NNP
cord-103536-etin5i7y	77	7	domain	domain	NN
cord-103536-etin5i7y	77	8	of	of	IN
cord-103536-etin5i7y	77	9	Tsg101	tsg101	DT
cord-103536-etin5i7y	77	10	independent	independent	NN
cord-103536-etin5i7y	77	11	of	of	IN
cord-103536-etin5i7y	77	12	its	-PRON-	PRP$
cord-103536-etin5i7y	77	13	oligomeric	oligomeric	JJ
cord-103536-etin5i7y	77	14	state	state	NN
cord-103536-etin5i7y	77	15	.	.	.
cord-103536-etin5i7y	78	1	Thus	thus	RB
cord-103536-etin5i7y	78	2	,	,	,
cord-103536-etin5i7y	78	3	monomeric	monomeric	JJ
cord-103536-etin5i7y	78	4	VP40	VP40	NNP
cord-103536-etin5i7y	78	5	recruits	recruit	VBZ
cord-103536-etin5i7y	78	6	Tsg101	tsg101	ADD
cord-103536-etin5i7y	78	7	to	to	IN
cord-103536-etin5i7y	78	8	the	the	DT
cord-103536-etin5i7y	78	9	site	site	NN
cord-103536-etin5i7y	78	10	of	of	IN
cord-103536-etin5i7y	78	11	budding	bud	VBG
cord-103536-etin5i7y	78	12	[	[	-LRB-
cord-103536-etin5i7y	78	13	26	26	CD
cord-103536-etin5i7y	78	14	,	,	,
cord-103536-etin5i7y	78	15	27	27	CD
cord-103536-etin5i7y	78	16	]	]	-RRB-
cord-103536-etin5i7y	78	17	,	,	,
cord-103536-etin5i7y	78	18	which	which	WDT
cord-103536-etin5i7y	78	19	in	in	IN
cord-103536-etin5i7y	78	20	turn	turn	NN
cord-103536-etin5i7y	78	21	might	may	MD
cord-103536-etin5i7y	78	22	recruit	recruit	VB
cord-103536-etin5i7y	78	23	the	the	DT
cord-103536-etin5i7y	78	24	complete	complete	JJ
cord-103536-etin5i7y	78	25	Vps	Vps	NNP
cord-103536-etin5i7y	78	26	machinery	machinery	NN
cord-103536-etin5i7y	78	27	for	for	IN
cord-103536-etin5i7y	78	28	efficient	efficient	JJ
cord-103536-etin5i7y	78	29	budding	budding	NN
cord-103536-etin5i7y	78	30	as	as	IN
cord-103536-etin5i7y	78	31	demonstrated	demonstrate	VBN
cord-103536-etin5i7y	78	32	in	in	IN
cord-103536-etin5i7y	78	33	case	case	NN
cord-103536-etin5i7y	78	34	of	of	IN
cord-103536-etin5i7y	78	35	HIV-1	HIV-1	NNP
cord-103536-etin5i7y	78	36	[	[	-LRB-
cord-103536-etin5i7y	78	37	12	12	CD
cord-103536-etin5i7y	78	38	]	]	-RRB-
cord-103536-etin5i7y	78	39	.	.	.
cord-103536-etin5i7y	79	1	The	the	DT
cord-103536-etin5i7y	79	2	late	late	JJ
cord-103536-etin5i7y	79	3	domain	domain	NN
cord-103536-etin5i7y	79	4	sequences	sequence	NNS
cord-103536-etin5i7y	79	5	are	be	VBP
cord-103536-etin5i7y	79	6	not	not	RB
cord-103536-etin5i7y	79	7	present	present	JJ
cord-103536-etin5i7y	79	8	in	in	IN
cord-103536-etin5i7y	79	9	the	the	DT
cord-103536-etin5i7y	79	10	crystal	crystal	NN
cord-103536-etin5i7y	79	11	structures	structure	NNS
cord-103536-etin5i7y	79	12	of	of	IN
cord-103536-etin5i7y	79	13	VP40	VP40	NNP
cord-103536-etin5i7y	79	14	as	as	IN
cord-103536-etin5i7y	79	15	they	-PRON-	PRP
cord-103536-etin5i7y	79	16	had	have	VBD
cord-103536-etin5i7y	79	17	been	be	VBN
cord-103536-etin5i7y	79	18	removed	remove	VBN
cord-103536-etin5i7y	79	19	by	by	IN
cord-103536-etin5i7y	79	20	proteolysis	proteolysis	NN
cord-103536-etin5i7y	79	21	for	for	IN
cord-103536-etin5i7y	79	22	efficient	efficient	JJ
cord-103536-etin5i7y	79	23	crystallisation	crystallisation	NN
cord-103536-etin5i7y	79	24	purposes	purpose	NNS
cord-103536-etin5i7y	79	25	.	.	.
cord-103536-etin5i7y	80	1	Note	note	VB
cord-103536-etin5i7y	80	2	that	that	IN
cord-103536-etin5i7y	80	3	the	the	DT
cord-103536-etin5i7y	80	4	C	c	NN
cord-103536-etin5i7y	80	5	-	-	HYPH
cord-103536-etin5i7y	80	6	terminal	terminal	NN
cord-103536-etin5i7y	80	7	ends	end	NNS
cord-103536-etin5i7y	80	8	connect	connect	VBP
cord-103536-etin5i7y	80	9	to	to	IN
cord-103536-etin5i7y	80	10	the	the	DT
cord-103536-etin5i7y	80	11	C	C	NNP
cord-103536-etin5i7y	80	12	-	-	HYPH
cord-103536-etin5i7y	80	13	terminal	terminal	NN
cord-103536-etin5i7y	80	14	domain	domain	NN
cord-103536-etin5i7y	80	15	,	,	,
cord-103536-etin5i7y	80	16	which	which	WDT
cord-103536-etin5i7y	80	17	is	be	VBZ
cord-103536-etin5i7y	80	18	missing	miss	VBG
cord-103536-etin5i7y	80	19	in	in	IN
cord-103536-etin5i7y	80	20	the	the	DT
cord-103536-etin5i7y	80	21	structure	structure	NN
cord-103536-etin5i7y	80	22	.	.	.
cord-103536-etin5i7y	81	1	This	this	DT
cord-103536-etin5i7y	81	2	is	be	VBZ
cord-103536-etin5i7y	81	3	also	also	RB
cord-103536-etin5i7y	81	4	indicated	indicate	VBN
cord-103536-etin5i7y	81	5	by	by	IN
cord-103536-etin5i7y	81	6	the	the	DT
cord-103536-etin5i7y	81	7	flexible	flexible	JJ
cord-103536-etin5i7y	81	8	attachment	attachment	NN
cord-103536-etin5i7y	81	9	of	of	IN
cord-103536-etin5i7y	81	10	two	two	CD
cord-103536-etin5i7y	81	11	C	c	NN
cord-103536-etin5i7y	81	12	-	-	HYPH
cord-103536-etin5i7y	81	13	terminal	terminal	NN
cord-103536-etin5i7y	81	14	domains	domain	NNS
cord-103536-etin5i7y	81	15	(	(	-LRB-
cord-103536-etin5i7y	81	16	white	white	NNP
cord-103536-etin5i7y	81	17	)	)	-RRB-
cord-103536-etin5i7y	81	18	.	.	.
cord-103536-etin5i7y	82	1	(	(	-LRB-
cord-103536-etin5i7y	82	2	c	c	LS
cord-103536-etin5i7y	82	3	)	)	-RRB-
cord-103536-etin5i7y	82	4	Full	full	JJ
cord-103536-etin5i7y	82	5	-	-	HYPH
cord-103536-etin5i7y	82	6	length	length	NN
cord-103536-etin5i7y	82	7	VP40	VP40	NNP
cord-103536-etin5i7y	82	8	can	can	MD
cord-103536-etin5i7y	82	9	be	be	VB
cord-103536-etin5i7y	82	10	also	also	RB
cord-103536-etin5i7y	82	11	activated	activate	VBN
cord-103536-etin5i7y	82	12	to	to	TO
cord-103536-etin5i7y	82	13	form	form	VB
cord-103536-etin5i7y	82	14	hexamers	hexamer	NNS
cord-103536-etin5i7y	82	15	,	,	,
cord-103536-etin5i7y	82	16	which	which	WDT
cord-103536-etin5i7y	82	17	is	be	VBZ
cord-103536-etin5i7y	82	18	mediated	mediate	VBN
cord-103536-etin5i7y	82	19	by	by	IN
cord-103536-etin5i7y	82	20	the	the	DT
cord-103536-etin5i7y	82	21	Nterminal	Nterminal	NNP
cord-103536-etin5i7y	82	22	domain	domain	NN
cord-103536-etin5i7y	82	23	.	.	.
cord-103536-etin5i7y	83	1	The	the	DT
cord-103536-etin5i7y	83	2	electron	electron	NN
cord-103536-etin5i7y	83	3	microscopy	microscopy	NN
cord-103536-etin5i7y	83	4	reconstruction	reconstruction	NN
cord-103536-etin5i7y	83	5	shows	show	VBZ
cord-103536-etin5i7y	83	6	that	that	IN
cord-103536-etin5i7y	83	7	two	two	CD
cord-103536-etin5i7y	83	8	N	n	CD
cord-103536-etin5i7y	83	9	-	-	HYPH
cord-103536-etin5i7y	83	10	terminal	terminal	NN
cord-103536-etin5i7y	83	11	domains	domain	NNS
cord-103536-etin5i7y	83	12	assemble	assemble	VBP
cord-103536-etin5i7y	83	13	to	to	TO
cord-103536-etin5i7y	83	14	create	create	VB
cord-103536-etin5i7y	83	15	a	a	DT
cord-103536-etin5i7y	83	16	ring	ring	NN
cord-103536-etin5i7y	83	17	-	-	HYPH
cord-103536-etin5i7y	83	18	structure	structure	NN
cord-103536-etin5i7y	83	19	having	have	VBG
cord-103536-etin5i7y	83	20	threefold	threefold	JJ
cord-103536-etin5i7y	83	21	-	-	HYPH
cord-103536-etin5i7y	83	22	symmetry	symmetry	NN
cord-103536-etin5i7y	83	23	.	.	.
cord-103536-etin5i7y	84	1	Like	like	IN
cord-103536-etin5i7y	84	2	in	in	IN
cord-103536-etin5i7y	84	3	the	the	DT
cord-103536-etin5i7y	84	4	octamer	octamer	NN
cord-103536-etin5i7y	84	5	structure	structure	NN
cord-103536-etin5i7y	84	6	the	the	DT
cord-103536-etin5i7y	84	7	C	C	NNP
cord-103536-etin5i7y	84	8	-	-	HYPH
cord-103536-etin5i7y	84	9	terminal	terminal	NN
cord-103536-etin5i7y	84	10	domains	domain	NNS
cord-103536-etin5i7y	84	11	are	be	VBP
cord-103536-etin5i7y	84	12	flexibly	flexibly	RB
cord-103536-etin5i7y	84	13	attached	attach	VBN
cord-103536-etin5i7y	84	14	to	to	IN
cord-103536-etin5i7y	84	15	the	the	DT
cord-103536-etin5i7y	84	16	ring	ring	NN
cord-103536-etin5i7y	84	17	structure	structure	NN
cord-103536-etin5i7y	84	18	as	as	IN
cord-103536-etin5i7y	84	19	indicated	indicate	VBN
cord-103536-etin5i7y	84	20	by	by	IN
cord-103536-etin5i7y	84	21	two	two	CD
cord-103536-etin5i7y	84	22	Cterminal	cterminal	JJ
cord-103536-etin5i7y	84	23	domains	domain	NNS
cord-103536-etin5i7y	84	24	and	and	CC
cord-103536-etin5i7y	84	25	by	by	IN
cord-103536-etin5i7y	84	26	the	the	DT
cord-103536-etin5i7y	84	27	electron	electron	NN
cord-103536-etin5i7y	84	28	microscopy	microscopy	NN
cord-103536-etin5i7y	84	29	reconstructions	reconstruction	NNS
cord-103536-etin5i7y	84	30	[	[	-LRB-
cord-103536-etin5i7y	84	31	23	23	CD
cord-103536-etin5i7y	84	32	]	]	-RRB-
cord-103536-etin5i7y	84	33	.	.	.
cord-103536-etin5i7y	85	1	The	the	DT
cord-103536-etin5i7y	85	2	structural	structural	JJ
cord-103536-etin5i7y	85	3	studies	study	NNS
cord-103536-etin5i7y	85	4	of	of	IN
cord-103536-etin5i7y	85	5	Ebola	Ebola	NNP
cord-103536-etin5i7y	85	6	virus	virus	NN
cord-103536-etin5i7y	86	1	VP40	VP40	NNS
cord-103536-etin5i7y	86	2	have	have	VBP
cord-103536-etin5i7y	86	3	now	now	RB
cord-103536-etin5i7y	86	4	firmly	firmly	RB
cord-103536-etin5i7y	86	5	established	establish	VBN
cord-103536-etin5i7y	86	6	three	three	CD
cord-103536-etin5i7y	86	7	conformations	conformation	NNS
cord-103536-etin5i7y	86	8	of	of	IN
cord-103536-etin5i7y	86	9	Ebola	Ebola	NNP
cord-103536-etin5i7y	86	10	virus	virus	NN
cord-103536-etin5i7y	86	11	VP40	VP40	NNP
cord-103536-etin5i7y	86	12	,	,	,
cord-103536-etin5i7y	86	13	although	although	IN
cord-103536-etin5i7y	86	14	their	-PRON-	PRP$
cord-103536-etin5i7y	86	15	role	role	NN
cord-103536-etin5i7y	86	16	in	in	IN
cord-103536-etin5i7y	86	17	assembly	assembly	NN
cord-103536-etin5i7y	86	18	and	and	CC
cord-103536-etin5i7y	86	19	budding	budding	JJ
cord-103536-etin5i7y	86	20	or	or	CC
cord-103536-etin5i7y	86	21	additional	additional	JJ
cord-103536-etin5i7y	86	22	functions	function	NNS
cord-103536-etin5i7y	86	23	during	during	IN
cord-103536-etin5i7y	86	24	the	the	DT
cord-103536-etin5i7y	86	25	life	life	NN
cord-103536-etin5i7y	86	26	cycle	cycle	NN
cord-103536-etin5i7y	86	27	of	of	IN
cord-103536-etin5i7y	86	28	Ebola	Ebola	NNP
cord-103536-etin5i7y	86	29	virus	virus	NN
cord-103536-etin5i7y	86	30	is	be	VBZ
cord-103536-etin5i7y	86	31	far	far	RB
cord-103536-etin5i7y	86	32	from	from	IN
cord-103536-etin5i7y	86	33	clear	clear	JJ
cord-103536-etin5i7y	86	34	.	.	.
cord-103536-etin5i7y	87	1	It	-PRON-	PRP
cord-103536-etin5i7y	87	2	is	be	VBZ
cord-103536-etin5i7y	87	3	,	,	,
cord-103536-etin5i7y	87	4	however	however	RB
cord-103536-etin5i7y	87	5	,	,	,
cord-103536-etin5i7y	87	6	an	an	DT
cord-103536-etin5i7y	87	7	interesting	interesting	JJ
cord-103536-etin5i7y	87	8	example	example	NN
cord-103536-etin5i7y	87	9	of	of	IN
cord-103536-etin5i7y	87	10	evolution	evolution	NN
cord-103536-etin5i7y	87	11	that	that	WDT
cord-103536-etin5i7y	87	12	packs	pack	VBZ
cord-103536-etin5i7y	87	13	different	different	JJ
cord-103536-etin5i7y	87	14	functional	functional	JJ
cord-103536-etin5i7y	87	15	aspects	aspect	NNS
cord-103536-etin5i7y	87	16	into	into	IN
cord-103536-etin5i7y	87	17	one	one	CD
cord-103536-etin5i7y	87	18	relatively	relatively	RB
cord-103536-etin5i7y	87	19	small	small	JJ
cord-103536-etin5i7y	87	20	protein	protein	NN
cord-103536-etin5i7y	87	21	probably	probably	RB
cord-103536-etin5i7y	87	22	due	due	IN
cord-103536-etin5i7y	87	23	to	to	IN
cord-103536-etin5i7y	87	24	the	the	DT
cord-103536-etin5i7y	87	25	limiting	limit	VBG
cord-103536-etin5i7y	87	26	size	size	NN
cord-103536-etin5i7y	87	27	of	of	IN
cord-103536-etin5i7y	87	28	the	the	DT
cord-103536-etin5i7y	87	29	viral	viral	JJ
cord-103536-etin5i7y	87	30	genome	genome	NN
cord-103536-etin5i7y	87	31	.	.	.
cord-103536-etin5i7y	88	1	The	the	DT
cord-103536-etin5i7y	88	2	structure	structure	NN
cord-103536-etin5i7y	88	3	of	of	IN
cord-103536-etin5i7y	88	4	the	the	DT
cord-103536-etin5i7y	88	5	matrix	matrix	NN
cord-103536-etin5i7y	88	6	protein	protein	NN
cord-103536-etin5i7y	88	7	form	form	NN
cord-103536-etin5i7y	88	8	vesicular	vesicular	JJ
cord-103536-etin5i7y	88	9	stomatitis	stomatitis	NN
cord-103536-etin5i7y	88	10	virus	virus	NN
cord-103536-etin5i7y	88	11	consists	consist	VBZ
cord-103536-etin5i7y	88	12	of	of	IN
cord-103536-etin5i7y	88	13	an	an	DT
cord-103536-etin5i7y	88	14	N	n	CD
cord-103536-etin5i7y	88	15	-	-	HYPH
cord-103536-etin5i7y	88	16	terminal	terminal	JJ
cord-103536-etin5i7y	88	17	part	part	NN
cord-103536-etin5i7y	88	18	composed	compose	VBN
cord-103536-etin5i7y	88	19	of	of	IN
cord-103536-etin5i7y	88	20	a	a	DT
cord-103536-etin5i7y	88	21	five	five	CD
cord-103536-etin5i7y	88	22	-	-	HYPH
cord-103536-etin5i7y	88	23	stranded	strand	VBN
cord-103536-etin5i7y	88	24	anti	anti	JJ
cord-103536-etin5i7y	88	25	-	-	JJ
cord-103536-etin5i7y	88	26	parallel	parallel	JJ
cord-103536-etin5i7y	88	27	b	b	NN
cord-103536-etin5i7y	88	28	-	-	HYPH
cord-103536-etin5i7y	88	29	sheet	sheet	NN
cord-103536-etin5i7y	88	30	packed	pack	VBN
cord-103536-etin5i7y	88	31	against	against	IN
cord-103536-etin5i7y	88	32	two	two	CD
cord-103536-etin5i7y	88	33	b	b	NN
cord-103536-etin5i7y	88	34	-	-	:
cord-103536-etin5i7y	88	35	helices	helix	NNS
cord-103536-etin5i7y	88	36	and	and	CC
cord-103536-etin5i7y	88	37	a	a	DT
cord-103536-etin5i7y	88	38	small	small	JJ
cord-103536-etin5i7y	88	39	C	c	NN
cord-103536-etin5i7y	88	40	-	-	HYPH
cord-103536-etin5i7y	88	41	terminal	terminal	NN
cord-103536-etin5i7y	88	42	part	part	NN
cord-103536-etin5i7y	88	43	made	make	VBN
cord-103536-etin5i7y	88	44	up	up	RP
cord-103536-etin5i7y	88	45	by	by	IN
cord-103536-etin5i7y	88	46	a	a	DT
cord-103536-etin5i7y	88	47	two	two	CD
cord-103536-etin5i7y	88	48	-	-	HYPH
cord-103536-etin5i7y	88	49	stranded	strand	VBN
cord-103536-etin5i7y	88	50	b	b	NN
cord-103536-etin5i7y	88	51	-	-	HYPH
cord-103536-etin5i7y	88	52	sheet	sheet	NN
cord-103536-etin5i7y	88	53	and	and	CC
cord-103536-etin5i7y	88	54	an	an	DT
cord-103536-etin5i7y	88	55	a	a	DT
cord-103536-etin5i7y	88	56	-	-	HYPH
cord-103536-etin5i7y	88	57	helix	helix	NN
cord-103536-etin5i7y	88	58	,	,	,
cord-103536-etin5i7y	88	59	which	which	WDT
cord-103536-etin5i7y	88	60	connects	connect	VBZ
cord-103536-etin5i7y	88	61	to	to	IN
cord-103536-etin5i7y	88	62	the	the	DT
cord-103536-etin5i7y	88	63	N	n	CD
cord-103536-etin5i7y	88	64	-	-	HYPH
cord-103536-etin5i7y	88	65	terminal	terminal	NN
cord-103536-etin5i7y	88	66	region	region	NN
cord-103536-etin5i7y	88	67	via	via	IN
cord-103536-etin5i7y	88	68	a	a	DT
cord-103536-etin5i7y	88	69	long	long	JJ
cord-103536-etin5i7y	88	70	linker	linker	NN
cord-103536-etin5i7y	88	71	(	(	-LRB-
cord-103536-etin5i7y	88	72	Fig	Fig	NNP
cord-103536-etin5i7y	88	73	.	.	.
cord-103536-etin5i7y	88	74	2(a	2(a	CD
cord-103536-etin5i7y	88	75	)	)	-RRB-
cord-103536-etin5i7y	88	76	)	)	-RRB-
cord-103536-etin5i7y	89	1	[	[	-LRB-
cord-103536-etin5i7y	89	2	31	31	CD
cord-103536-etin5i7y	89	3	]	]	-RRB-
cord-103536-etin5i7y	89	4	.	.	.
cord-103536-etin5i7y	90	1	As	as	IN
cord-103536-etin5i7y	90	2	with	with	IN
cord-103536-etin5i7y	90	3	Ebola	Ebola	NNP
cord-103536-etin5i7y	90	4	VP40	VP40	NNP
cord-103536-etin5i7y	90	5	,	,	,
cord-103536-etin5i7y	90	6	the	the	DT
cord-103536-etin5i7y	90	7	vesiculovirus	vesiculovirus	NNP
cord-103536-etin5i7y	90	8	matrix	matrix	NNP
cord-103536-etin5i7y	90	9	protein	protein	NNP
cord-103536-etin5i7y	90	10	displays	display	VBZ
cord-103536-etin5i7y	90	11	a	a	DT
cord-103536-etin5i7y	90	12	new	new	JJ
cord-103536-etin5i7y	90	13	fold	fold	NN
cord-103536-etin5i7y	90	14	.	.	.
cord-103536-etin5i7y	91	1	No	no	DT
cord-103536-etin5i7y	91	2	defined	define	VBN
cord-103536-etin5i7y	91	3	oligomeric	oligomeric	JJ
cord-103536-etin5i7y	91	4	structures	structure	NNS
cord-103536-etin5i7y	91	5	have	have	VBP
cord-103536-etin5i7y	91	6	been	be	VBN
cord-103536-etin5i7y	91	7	described	describe	VBN
cord-103536-etin5i7y	91	8	for	for	IN
cord-103536-etin5i7y	91	9	VSV	VSV	NNP
cord-103536-etin5i7y	91	10	M	M	NNP
cord-103536-etin5i7y	91	11	,	,	,
cord-103536-etin5i7y	91	12	which	which	WDT
cord-103536-etin5i7y	91	13	,	,	,
cord-103536-etin5i7y	91	14	however	however	RB
cord-103536-etin5i7y	91	15	,	,	,
cord-103536-etin5i7y	91	16	polymerises	polymerise	NNS
cord-103536-etin5i7y	91	17	in	in	IN
cord-103536-etin5i7y	91	18	vitro	vitro	FW
cord-103536-etin5i7y	91	19	[	[	-LRB-
cord-103536-etin5i7y	91	20	32	32	CD
cord-103536-etin5i7y	91	21	]	]	-RRB-
cord-103536-etin5i7y	91	22	.	.	.
cord-103536-etin5i7y	92	1	For	for	IN
cord-103536-etin5i7y	92	2	structure	structure	NN
cord-103536-etin5i7y	92	3	determination	determination	NN
cord-103536-etin5i7y	92	4	,	,	,
cord-103536-etin5i7y	92	5	VSV	VSV	NNP
cord-103536-etin5i7y	92	6	M	M	NNP
cord-103536-etin5i7y	92	7	was	be	VBD
cord-103536-etin5i7y	92	8	purified	purify	VBN
cord-103536-etin5i7y	92	9	from	from	IN
cord-103536-etin5i7y	92	10	virus	virus	NN
cord-103536-etin5i7y	92	11	and	and	CC
cord-103536-etin5i7y	92	12	solubilized	solubilize	VBN
cord-103536-etin5i7y	92	13	by	by	IN
cord-103536-etin5i7y	92	14	thermolysin	thermolysin	NNP
cord-103536-etin5i7y	92	15	cleavage	cleavage	NN
cord-103536-etin5i7y	92	16	,	,	,
cord-103536-etin5i7y	92	17	which	which	WDT
cord-103536-etin5i7y	92	18	removes	remove	VBZ
cord-103536-etin5i7y	92	19	residues	residue	NNS
cord-103536-etin5i7y	92	20	1	1	CD
cord-103536-etin5i7y	92	21	-	-	SYM
cord-103536-etin5i7y	92	22	49	49	CD
cord-103536-etin5i7y	92	23	and	and	CC
cord-103536-etin5i7y	92	24	121	121	CD
cord-103536-etin5i7y	92	25	-	-	SYM
cord-103536-etin5i7y	92	26	122/124	122/124	CD
cord-103536-etin5i7y	92	27	,	,	,
cord-103536-etin5i7y	92	28	thus	thus	RB
cord-103536-etin5i7y	92	29	preventing	prevent	VBG
cord-103536-etin5i7y	92	30	polymerisation	polymerisation	NN
cord-103536-etin5i7y	92	31	(	(	-LRB-
cord-103536-etin5i7y	92	32	Fig	Fig	NNP
cord-103536-etin5i7y	92	33	.	.	.
cord-103536-etin5i7y	92	34	2(a	2(a	CD
cord-103536-etin5i7y	92	35	)	)	-RRB-
cord-103536-etin5i7y	92	36	)	)	-RRB-
cord-103536-etin5i7y	92	37	.	.	.
cord-103536-etin5i7y	93	1	Full	full	JJ
cord-103536-etin5i7y	93	2	length	length	NN
cord-103536-etin5i7y	93	3	VSV	VSV	NNP
cord-103536-etin5i7y	93	4	M	M	NNP
cord-103536-etin5i7y	93	5	has	have	VBZ
cord-103536-etin5i7y	93	6	a	a	DT
cord-103536-etin5i7y	93	7	high	high	JJ
cord-103536-etin5i7y	93	8	tendency	tendency	NN
cord-103536-etin5i7y	93	9	to	to	IN
cord-103536-etin5i7y	93	10	self	self	NN
cord-103536-etin5i7y	93	11	-	-	HYPH
cord-103536-etin5i7y	93	12	associate	associate	NN
cord-103536-etin5i7y	93	13	into	into	IN
cord-103536-etin5i7y	93	14	large	large	JJ
cord-103536-etin5i7y	93	15	multimers	multimer	NNS
cord-103536-etin5i7y	93	16	[	[	-LRB-
cord-103536-etin5i7y	93	17	33	33	CD
cord-103536-etin5i7y	93	18	]	]	-RRB-
cord-103536-etin5i7y	93	19	,	,	,
cord-103536-etin5i7y	93	20	which	which	WDT
cord-103536-etin5i7y	93	21	is	be	VBZ
cord-103536-etin5i7y	93	22	sensitive	sensitive	JJ
cord-103536-etin5i7y	93	23	to	to	IN
cord-103536-etin5i7y	93	24	salt	salt	NN
cord-103536-etin5i7y	93	25	treatment	treatment	NN
cord-103536-etin5i7y	93	26	in	in	IN
cord-103536-etin5i7y	93	27	vitro	vitro	FW
cord-103536-etin5i7y	93	28	[	[	-LRB-
cord-103536-etin5i7y	93	29	34	34	CD
cord-103536-etin5i7y	93	30	]	]	-RRB-
cord-103536-etin5i7y	93	31	.	.	.
cord-103536-etin5i7y	94	1	Expression	expression	NN
cord-103536-etin5i7y	94	2	of	of	IN
cord-103536-etin5i7y	94	3	M	M	NNP
cord-103536-etin5i7y	94	4	protein	protein	NN
cord-103536-etin5i7y	94	5	induces	induce	VBZ
cord-103536-etin5i7y	94	6	the	the	DT
cord-103536-etin5i7y	94	7	formation	formation	NN
cord-103536-etin5i7y	94	8	and	and	CC
cord-103536-etin5i7y	94	9	budding	budding	NN
cord-103536-etin5i7y	94	10	of	of	IN
cord-103536-etin5i7y	94	11	vesicles	vesicle	NNS
cord-103536-etin5i7y	94	12	,	,	,
cord-103536-etin5i7y	94	13	which	which	WDT
cord-103536-etin5i7y	94	14	is	be	VBZ
cord-103536-etin5i7y	94	15	consistent	consistent	JJ
cord-103536-etin5i7y	94	16	with	with	IN
cord-103536-etin5i7y	94	17	its	-PRON-	PRP$
cord-103536-etin5i7y	94	18	membrane	membrane	NN
cord-103536-etin5i7y	94	19	association	association	NN
cord-103536-etin5i7y	94	20	and	and	CC
cord-103536-etin5i7y	94	21	polymerisation	polymerisation	NN
cord-103536-etin5i7y	94	22	activities	activity	NNS
cord-103536-etin5i7y	94	23	.	.	.
cord-103536-etin5i7y	95	1	These	these	DT
cord-103536-etin5i7y	95	2	particles	particle	NNS
cord-103536-etin5i7y	95	3	,	,	,
cord-103536-etin5i7y	95	4	however	however	RB
cord-103536-etin5i7y	95	5	,	,	,
cord-103536-etin5i7y	95	6	do	do	VBP
cord-103536-etin5i7y	95	7	not	not	RB
cord-103536-etin5i7y	95	8	show	show	VB
cord-103536-etin5i7y	95	9	the	the	DT
cord-103536-etin5i7y	95	10	characteristic	characteristic	JJ
cord-103536-etin5i7y	95	11	bulletshaped	bulletshaped	JJ
cord-103536-etin5i7y	95	12	structure	structure	NN
cord-103536-etin5i7y	95	13	of	of	IN
cord-103536-etin5i7y	95	14	rhabdoviruses	rhabdovirus	NNS
cord-103536-etin5i7y	95	15	indicating	indicate	VBG
cord-103536-etin5i7y	95	16	that	that	IN
cord-103536-etin5i7y	95	17	other	other	JJ
cord-103536-etin5i7y	95	18	viral	viral	JJ
cord-103536-etin5i7y	95	19	components	component	NNS
cord-103536-etin5i7y	95	20	such	such	JJ
cord-103536-etin5i7y	95	21	as	as	IN
cord-103536-etin5i7y	95	22	nucleocapsids	nucleocapsid	NNS
cord-103536-etin5i7y	95	23	are	be	VBP
cord-103536-etin5i7y	95	24	responsible	responsible	JJ
cord-103536-etin5i7y	95	25	for	for	IN
cord-103536-etin5i7y	95	26	the	the	DT
cord-103536-etin5i7y	95	27	distinct	distinct	JJ
cord-103536-etin5i7y	95	28	morphology	morphology	NN
cord-103536-etin5i7y	95	29	of	of	IN
cord-103536-etin5i7y	95	30	VSV	VSV	NNP
cord-103536-etin5i7y	95	31	[	[	-LRB-
cord-103536-etin5i7y	95	32	3	3	CD
cord-103536-etin5i7y	95	33	]	]	-RRB-
cord-103536-etin5i7y	95	34	.	.	.
cord-103536-etin5i7y	96	1	The	the	DT
cord-103536-etin5i7y	96	2	structure	structure	NN
cord-103536-etin5i7y	96	3	can	can	MD
cord-103536-etin5i7y	96	4	be	be	VB
cord-103536-etin5i7y	96	5	considered	consider	VBN
cord-103536-etin5i7y	96	6	to	to	TO
cord-103536-etin5i7y	96	7	represent	represent	VB
cord-103536-etin5i7y	96	8	the	the	DT
cord-103536-etin5i7y	96	9	membrane	membrane	NN
cord-103536-etin5i7y	96	10	-	-	HYPH
cord-103536-etin5i7y	96	11	activated	activate	VBN
cord-103536-etin5i7y	96	12	form	form	NN
cord-103536-etin5i7y	96	13	that	that	WDT
cord-103536-etin5i7y	96	14	,	,	,
cord-103536-etin5i7y	96	15	however	however	RB
cord-103536-etin5i7y	96	16	,	,	,
cord-103536-etin5i7y	96	17	no	no	RB
cord-103536-etin5i7y	96	18	longer	long	RBR
cord-103536-etin5i7y	96	19	binds	bind	VBZ
cord-103536-etin5i7y	96	20	artificial	artificial	JJ
cord-103536-etin5i7y	96	21	membranes	membrane	NNS
cord-103536-etin5i7y	96	22	due	due	JJ
cord-103536-etin5i7y	96	23	to	to	IN
cord-103536-etin5i7y	96	24	proteolytic	proteolytic	JJ
cord-103536-etin5i7y	96	25	removal	removal	NN
cord-103536-etin5i7y	96	26	of	of	IN
cord-103536-etin5i7y	96	27	residues	residue	NNS
cord-103536-etin5i7y	96	28	121	121	CD
cord-103536-etin5i7y	96	29	-	-	HYPH
cord-103536-etin5i7y	96	30	122/124	122/124	CD
cord-103536-etin5i7y	96	31	[	[	-LRB-
cord-103536-etin5i7y	96	32	31	31	CD
cord-103536-etin5i7y	96	33	]	]	-RRB-
cord-103536-etin5i7y	96	34	.	.	.
cord-103536-etin5i7y	97	1	It	-PRON-	PRP
cord-103536-etin5i7y	97	2	is	be	VBZ
cord-103536-etin5i7y	97	3	conceivable	conceivable	JJ
cord-103536-etin5i7y	97	4	that	that	IN
cord-103536-etin5i7y	97	5	VSV	VSV	NNP
cord-103536-etin5i7y	97	6	M	M	NNP
cord-103536-etin5i7y	97	7	adopts	adopt	VBZ
cord-103536-etin5i7y	97	8	a	a	DT
cord-103536-etin5i7y	97	9	different	different	JJ
cord-103536-etin5i7y	97	10	conformation	conformation	NN
cord-103536-etin5i7y	97	11	before	before	IN
cord-103536-etin5i7y	97	12	activation	activation	NN
cord-103536-etin5i7y	97	13	,	,	,
cord-103536-etin5i7y	97	14	as	as	IN
cord-103536-etin5i7y	97	15	cellular	cellular	JJ
cord-103536-etin5i7y	97	16	expression	expression	NN
cord-103536-etin5i7y	97	17	does	do	VBZ
cord-103536-etin5i7y	97	18	not	not	RB
cord-103536-etin5i7y	97	19	per	per	FW
cord-103536-etin5i7y	97	20	se	se	FW
cord-103536-etin5i7y	97	21	lead	lead	NN
cord-103536-etin5i7y	97	22	to	to	IN
cord-103536-etin5i7y	97	23	polymerisation	polymerisation	NN
cord-103536-etin5i7y	97	24	and	and	CC
cord-103536-etin5i7y	97	25	membrane	membrane	NN
cord-103536-etin5i7y	97	26	binding	bind	VBG
cord-103536-etin5i7y	97	27	but	but	CC
cord-103536-etin5i7y	97	28	produces	produce	VBZ
cord-103536-etin5i7y	97	29	mostly	mostly	RB
cord-103536-etin5i7y	97	30	cytoplasmic	cytoplasmic	JJ
cord-103536-etin5i7y	97	31	M	M	NNP
cord-103536-etin5i7y	97	32	[	[	-LRB-
cord-103536-etin5i7y	97	33	33	33	CD
cord-103536-etin5i7y	97	34	,	,	,
cord-103536-etin5i7y	97	35	35	35	CD
cord-103536-etin5i7y	97	36	]	]	-RRB-
cord-103536-etin5i7y	97	37	.	.	.
cord-103536-etin5i7y	98	1	This	this	DT
cord-103536-etin5i7y	98	2	putative	putative	JJ
cord-103536-etin5i7y	98	3	other	other	JJ
cord-103536-etin5i7y	98	4	conformation(s	conformation(s	NNP
cord-103536-etin5i7y	98	5	)	)	-RRB-
cord-103536-etin5i7y	98	6	might	may	MD
cord-103536-etin5i7y	98	7	then	then	RB
cord-103536-etin5i7y	98	8	be	be	VB
cord-103536-etin5i7y	98	9	also	also	RB
cord-103536-etin5i7y	98	10	responsible	responsible	JJ
cord-103536-etin5i7y	98	11	for	for	IN
cord-103536-etin5i7y	98	12	secondary	secondary	JJ
cord-103536-etin5i7y	98	13	functions	function	NNS
cord-103536-etin5i7y	98	14	of	of	IN
cord-103536-etin5i7y	98	15	VSV	VSV	NNP
cord-103536-etin5i7y	98	16	M	M	NNP
cord-103536-etin5i7y	98	17	such	such	JJ
cord-103536-etin5i7y	98	18	as	as	IN
cord-103536-etin5i7y	98	19	,	,	,
cord-103536-etin5i7y	98	20	inhibition	inhibition	NN
cord-103536-etin5i7y	98	21	of	of	IN
cord-103536-etin5i7y	98	22	transcription	transcription	NN
cord-103536-etin5i7y	98	23	and	and	CC
cord-103536-etin5i7y	98	24	nucleocytoplasmic	nucleocytoplasmic	NNP
cord-103536-etin5i7y	98	25	transport	transport	NN
cord-103536-etin5i7y	98	26	,	,	,
cord-103536-etin5i7y	98	27	nuclear	nuclear	JJ
cord-103536-etin5i7y	98	28	localisation	localisation	NN
cord-103536-etin5i7y	98	29	and	and	CC
cord-103536-etin5i7y	98	30	cell	cell	NN
cord-103536-etin5i7y	98	31	rounding	round	VBG
cord-103536-etin5i7y	98	32	due	due	IN
cord-103536-etin5i7y	98	33	to	to	IN
cord-103536-etin5i7y	98	34	the	the	DT
cord-103536-etin5i7y	98	35	induction	induction	NN
cord-103536-etin5i7y	98	36	of	of	IN
cord-103536-etin5i7y	98	37	apoptosis	apoptosis	NN
cord-103536-etin5i7y	98	38	[	[	-LRB-
cord-103536-etin5i7y	98	39	36	36	CD
cord-103536-etin5i7y	98	40	]	]	-RRB-
cord-103536-etin5i7y	99	1	[	[	-LRB-
cord-103536-etin5i7y	99	2	37	37	CD
cord-103536-etin5i7y	99	3	]	]	-RRB-
cord-103536-etin5i7y	99	4	[	[	-LRB-
cord-103536-etin5i7y	99	5	38	38	CD
cord-103536-etin5i7y	99	6	]	]	-RRB-
cord-103536-etin5i7y	100	1	[	[	-LRB-
cord-103536-etin5i7y	100	2	39	39	CD
cord-103536-etin5i7y	100	3	]	]	-RRB-
cord-103536-etin5i7y	100	4	[	[	-LRB-
cord-103536-etin5i7y	100	5	40	40	CD
cord-103536-etin5i7y	100	6	]	]	-RRB-
cord-103536-etin5i7y	100	7	.	.	.
cord-103536-etin5i7y	101	1	VSV	VSV	NNP
cord-103536-etin5i7y	101	2	M	M	NNP
cord-103536-etin5i7y	101	3	has	have	VBZ
cord-103536-etin5i7y	101	4	been	be	VBN
cord-103536-etin5i7y	101	5	also	also	RB
cord-103536-etin5i7y	101	6	implicated	implicate	VBN
cord-103536-etin5i7y	101	7	in	in	IN
cord-103536-etin5i7y	101	8	nucleocapsid	nucleocapsid	NN
cord-103536-etin5i7y	101	9	condensation	condensation	NN
cord-103536-etin5i7y	101	10	[	[	-LRB-
cord-103536-etin5i7y	101	11	41	41	CD
cord-103536-etin5i7y	101	12	]	]	-RRB-
cord-103536-etin5i7y	101	13	,	,	,
cord-103536-etin5i7y	101	14	which	which	WDT
cord-103536-etin5i7y	101	15	may	may	MD
cord-103536-etin5i7y	101	16	be	be	VB
cord-103536-etin5i7y	101	17	similar	similar	JJ
cord-103536-etin5i7y	101	18	to	to	IN
cord-103536-etin5i7y	101	19	the	the	DT
cord-103536-etin5i7y	101	20	function	function	NN
cord-103536-etin5i7y	101	21	of	of	IN
cord-103536-etin5i7y	101	22	Ebola	Ebola	NNP
cord-103536-etin5i7y	101	23	virus	virus	NN
cord-103536-etin5i7y	101	24	VP24	VP24	NNP
cord-103536-etin5i7y	101	25	in	in	IN
cord-103536-etin5i7y	101	26	nucleocapsid	nucleocapsid	NNP
cord-103536-etin5i7y	101	27	formation	formation	NN
cord-103536-etin5i7y	101	28	[	[	-LRB-
cord-103536-etin5i7y	101	29	42	42	CD
cord-103536-etin5i7y	101	30	]	]	-RRB-
cord-103536-etin5i7y	101	31	.	.	.
cord-103536-etin5i7y	102	1	In	in	IN
cord-103536-etin5i7y	102	2	addition	addition	NN
cord-103536-etin5i7y	102	3	,	,	,
cord-103536-etin5i7y	102	4	VSV	VSV	NNP
cord-103536-etin5i7y	102	5	M	M	NNP
cord-103536-etin5i7y	102	6	contains	contain	VBZ
cord-103536-etin5i7y	102	7	the	the	DT
cord-103536-etin5i7y	102	8	late	late	JJ
cord-103536-etin5i7y	102	9	domain	domain	NN
cord-103536-etin5i7y	102	10	motifs	motifs	VBP
cord-103536-etin5i7y	102	11	PPPY	PPPY	NNS
cord-103536-etin5i7y	102	12	and	and	CC
cord-103536-etin5i7y	102	13	PSAP	PSAP	NNPS
cord-103536-etin5i7y	102	14	within	within	IN
cord-103536-etin5i7y	102	15	the	the	DT
cord-103536-etin5i7y	102	16	N	n	CD
cord-103536-etin5i7y	102	17	-	-	HYPH
cord-103536-etin5i7y	102	18	terminal	terminal	NN
cord-103536-etin5i7y	102	19	40	40	CD
cord-103536-etin5i7y	102	20	residues	residue	NNS
cord-103536-etin5i7y	102	21	(	(	-LRB-
cord-103536-etin5i7y	102	22	[	[	-LRB-
cord-103536-etin5i7y	102	23	10	10	CD
cord-103536-etin5i7y	102	24	]	]	-RRB-
cord-103536-etin5i7y	102	25	and	and	CC
cord-103536-etin5i7y	102	26	references	reference	NNS
cord-103536-etin5i7y	102	27	therein	therein	RB
cord-103536-etin5i7y	102	28	)	)	-RRB-
cord-103536-etin5i7y	102	29	,	,	,
cord-103536-etin5i7y	102	30	which	which	WDT
cord-103536-etin5i7y	102	31	are	be	VBP
cord-103536-etin5i7y	102	32	missing	miss	VBG
cord-103536-etin5i7y	102	33	in	in	IN
cord-103536-etin5i7y	102	34	the	the	DT
cord-103536-etin5i7y	102	35	crystal	crystal	NN
cord-103536-etin5i7y	102	36	structure	structure	NN
cord-103536-etin5i7y	102	37	.	.	.
cord-103536-etin5i7y	103	1	The	the	DT
cord-103536-etin5i7y	103	2	PPPY	PPPY	NNP
cord-103536-etin5i7y	103	3	motif	motif	NN
cord-103536-etin5i7y	103	4	was	be	VBD
cord-103536-etin5i7y	103	5	shown	show	VBN
cord-103536-etin5i7y	103	6	to	to	TO
cord-103536-etin5i7y	103	7	interact	interact	VB
cord-103536-etin5i7y	103	8	with	with	IN
cord-103536-etin5i7y	103	9	mouse	mouse	NN
cord-103536-etin5i7y	103	10	Nedd4	Nedd4	NNP
cord-103536-etin5i7y	103	11	and	and	CC
cord-103536-etin5i7y	103	12	proteasome	proteasome	NN
cord-103536-etin5i7y	103	13	inhibitors	inhibitor	NNS
cord-103536-etin5i7y	103	14	reduced	reduce	VBD
cord-103536-etin5i7y	103	15	virus	virus	NN
cord-103536-etin5i7y	103	16	titers	titer	NNS
cord-103536-etin5i7y	103	17	implicating	implicate	VBG
cord-103536-etin5i7y	103	18	ubiquitin	ubiquitin	NN
cord-103536-etin5i7y	103	19	in	in	IN
cord-103536-etin5i7y	103	20	virus	virus	NN
cord-103536-etin5i7y	103	21	budding	bud	VBG
cord-103536-etin5i7y	103	22	[	[	-LRB-
cord-103536-etin5i7y	103	23	43	43	CD
cord-103536-etin5i7y	103	24	]	]	-RRB-
cord-103536-etin5i7y	103	25	.	.	.
cord-103536-etin5i7y	104	1	The	the	DT
cord-103536-etin5i7y	104	2	question	question	NN
cord-103536-etin5i7y	104	3	Fig	Fig	NNP
cord-103536-etin5i7y	104	4	.	.	NNP
cord-103536-etin5i7y	104	5	2	2	CD
cord-103536-etin5i7y	104	6	.	.	.
cord-103536-etin5i7y	105	1	Ribbon	ribbon	NN
cord-103536-etin5i7y	105	2	diagrams	diagram	NNS
cord-103536-etin5i7y	105	3	of	of	IN
cord-103536-etin5i7y	105	4	other	other	JJ
cord-103536-etin5i7y	105	5	known	know	VBN
cord-103536-etin5i7y	105	6	matrix	matrix	NN
cord-103536-etin5i7y	105	7	protein	protein	NN
cord-103536-etin5i7y	105	8	structures	structure	NNS
cord-103536-etin5i7y	105	9	.	.	.
cord-103536-etin5i7y	106	1	The	the	DT
cord-103536-etin5i7y	106	2	N	N	NNP
cord-103536-etin5i7y	106	3	-	-	HYPH
cord-103536-etin5i7y	106	4	and	and	CC
cord-103536-etin5i7y	106	5	C	c	NN
cord-103536-etin5i7y	106	6	-	-	HYPH
cord-103536-etin5i7y	106	7	terminal	terminal	NN
cord-103536-etin5i7y	106	8	ends	end	NNS
cord-103536-etin5i7y	106	9	are	be	VBP
cord-103536-etin5i7y	106	10	indicated	indicate	VBN
cord-103536-etin5i7y	106	11	.	.	.
cord-103536-etin5i7y	107	1	Note	note	VB
cord-103536-etin5i7y	107	2	that	that	IN
cord-103536-etin5i7y	107	3	the	the	DT
cord-103536-etin5i7y	107	4	folds	fold	NNS
cord-103536-etin5i7y	107	5	of	of	IN
cord-103536-etin5i7y	108	1	Ebola	Ebola	NNP
cord-103536-etin5i7y	108	2	virus	virus	NN
cord-103536-etin5i7y	108	3	VP40	VP40	NNP
cord-103536-etin5i7y	109	1	(	(	-LRB-
cord-103536-etin5i7y	109	2	Fig	Fig	NNP
cord-103536-etin5i7y	109	3	.	.	.
cord-103536-etin5i7y	109	4	1(a	1(a	CD
cord-103536-etin5i7y	109	5	)	)	-RRB-
cord-103536-etin5i7y	109	6	)	)	-RRB-
cord-103536-etin5i7y	110	1	and	and	CC
cord-103536-etin5i7y	110	2	the	the	DT
cord-103536-etin5i7y	110	3	structures	structure	NNS
cord-103536-etin5i7y	110	4	shown	show	VBN
cord-103536-etin5i7y	110	5	here	here	RB
cord-103536-etin5i7y	110	6	are	be	VBP
cord-103536-etin5i7y	110	7	all	all	RB
cord-103536-etin5i7y	110	8	different	different	JJ
cord-103536-etin5i7y	110	9	.	.	.
cord-103536-etin5i7y	111	1	remains	remain	VBZ
cord-103536-etin5i7y	111	2	whether	whether	IN
cord-103536-etin5i7y	111	3	any	any	DT
cord-103536-etin5i7y	111	4	conformational	conformational	JJ
cord-103536-etin5i7y	111	5	diversity	diversity	NN
cord-103536-etin5i7y	111	6	of	of	IN
cord-103536-etin5i7y	111	7	VSV	VSV	NNP
cord-103536-etin5i7y	111	8	M	M	NNP
cord-103536-etin5i7y	111	9	might	may	MD
cord-103536-etin5i7y	111	10	contribute	contribute	VB
cord-103536-etin5i7y	111	11	to	to	IN
cord-103536-etin5i7y	111	12	its	-PRON-	PRP$
cord-103536-etin5i7y	111	13	different	different	JJ
cord-103536-etin5i7y	111	14	functions	function	NNS
cord-103536-etin5i7y	111	15	.	.	.
cord-103536-etin5i7y	112	1	The	the	DT
cord-103536-etin5i7y	112	2	structure	structure	NN
cord-103536-etin5i7y	112	3	of	of	IN
cord-103536-etin5i7y	112	4	the	the	DT
cord-103536-etin5i7y	112	5	N	n	CD
cord-103536-etin5i7y	112	6	-	-	HYPH
cord-103536-etin5i7y	112	7	terminal	terminal	NN
cord-103536-etin5i7y	112	8	domain	domain	NN
cord-103536-etin5i7y	112	9	of	of	IN
cord-103536-etin5i7y	112	10	Influenza	Influenza	NNP
cord-103536-etin5i7y	112	11	virus	virus	NN
cord-103536-etin5i7y	112	12	M1	M1	NNP
cord-103536-etin5i7y	112	13	protein	protein	NN
cord-103536-etin5i7y	112	14	has	have	VBZ
cord-103536-etin5i7y	112	15	been	be	VBN
cord-103536-etin5i7y	112	16	solved	solve	VBN
cord-103536-etin5i7y	112	17	at	at	IN
cord-103536-etin5i7y	112	18	pH	pH	NNP
cord-103536-etin5i7y	112	19	4.0	4.0	CD
cord-103536-etin5i7y	112	20	[	[	-LRB-
cord-103536-etin5i7y	112	21	44	44	CD
cord-103536-etin5i7y	112	22	]	]	-RRB-
cord-103536-etin5i7y	112	23	and	and	CC
cord-103536-etin5i7y	112	24	at	at	IN
cord-103536-etin5i7y	112	25	neutral	neutral	JJ
cord-103536-etin5i7y	112	26	pH	pH	NNP
cord-103536-etin5i7y	112	27	[	[	-LRB-
cord-103536-etin5i7y	112	28	45	45	CD
cord-103536-etin5i7y	112	29	]	]	-RRB-
cord-103536-etin5i7y	112	30	.	.	.
cord-103536-etin5i7y	113	1	Both	both	DT
cord-103536-etin5i7y	113	2	structures	structure	NNS
cord-103536-etin5i7y	113	3	are	be	VBP
cord-103536-etin5i7y	113	4	identical	identical	JJ
cord-103536-etin5i7y	113	5	and	and	CC
cord-103536-etin5i7y	113	6	consist	consist	VBP
cord-103536-etin5i7y	113	7	of	of	IN
cord-103536-etin5i7y	113	8	two	two	CD
cord-103536-etin5i7y	113	9	four	four	CD
cord-103536-etin5i7y	113	10	-	-	HYPH
cord-103536-etin5i7y	113	11	helical	helical	JJ
cord-103536-etin5i7y	113	12	bundle	bundle	NN
cord-103536-etin5i7y	113	13	subdomains	subdomain	NNS
cord-103536-etin5i7y	113	14	that	that	WDT
cord-103536-etin5i7y	113	15	pack	pack	VBP
cord-103536-etin5i7y	113	16	against	against	IN
cord-103536-etin5i7y	113	17	each	each	DT
cord-103536-etin5i7y	113	18	other	other	JJ
cord-103536-etin5i7y	113	19	through	through	IN
cord-103536-etin5i7y	113	20	a	a	DT
cord-103536-etin5i7y	113	21	hydrophobic	hydrophobic	JJ
cord-103536-etin5i7y	113	22	interface	interface	NN
cord-103536-etin5i7y	113	23	(	(	-LRB-
cord-103536-etin5i7y	113	24	Fig	Fig	NNP
cord-103536-etin5i7y	113	25	.	.	.
cord-103536-etin5i7y	113	26	2(b	2(b	CD
cord-103536-etin5i7y	113	27	)	)	-RRB-
cord-103536-etin5i7y	113	28	)	)	-RRB-
cord-103536-etin5i7y	113	29	.	.	.
cord-103536-etin5i7y	114	1	The	the	DT
cord-103536-etin5i7y	114	2	fold	fold	NN
cord-103536-etin5i7y	114	3	is	be	VBZ
cord-103536-etin5i7y	114	4	again	again	RB
cord-103536-etin5i7y	114	5	different	different	JJ
cord-103536-etin5i7y	114	6	from	from	IN
cord-103536-etin5i7y	114	7	other	other	JJ
cord-103536-etin5i7y	114	8	known	know	VBN
cord-103536-etin5i7y	114	9	matrix	matrix	NN
cord-103536-etin5i7y	114	10	protein	protein	NN
cord-103536-etin5i7y	114	11	structures	structure	NNS
cord-103536-etin5i7y	114	12	.	.	.
cord-103536-etin5i7y	115	1	One	one	CD
cord-103536-etin5i7y	115	2	side	side	NN
cord-103536-etin5i7y	115	3	of	of	IN
cord-103536-etin5i7y	115	4	the	the	DT
cord-103536-etin5i7y	115	5	N	n	CD
cord-103536-etin5i7y	115	6	-	-	HYPH
cord-103536-etin5i7y	115	7	terminal	terminal	NN
cord-103536-etin5i7y	115	8	domain	domain	NN
cord-103536-etin5i7y	115	9	of	of	IN
cord-103536-etin5i7y	115	10	M1	M1	NNP
cord-103536-etin5i7y	115	11	is	be	VBZ
cord-103536-etin5i7y	115	12	strictly	strictly	RB
cord-103536-etin5i7y	115	13	positively	positively	RB
cord-103536-etin5i7y	115	14	charged	charge	VBN
cord-103536-etin5i7y	115	15	while	while	IN
cord-103536-etin5i7y	115	16	the	the	DT
cord-103536-etin5i7y	115	17	opposite	opposite	JJ
cord-103536-etin5i7y	115	18	one	one	CD
cord-103536-etin5i7y	115	19	exhibits	exhibit	VBZ
cord-103536-etin5i7y	115	20	an	an	DT
cord-103536-etin5i7y	115	21	all	all	RB
cord-103536-etin5i7y	115	22	-	-	HYPH
cord-103536-etin5i7y	115	23	negative	negative	JJ
cord-103536-etin5i7y	115	24	charge	charge	NN
cord-103536-etin5i7y	115	25	[	[	-LRB-
cord-103536-etin5i7y	115	26	45	45	CD
cord-103536-etin5i7y	115	27	]	]	-RRB-
cord-103536-etin5i7y	115	28	.	.	.
cord-103536-etin5i7y	116	1	Proteolysis	proteolysis	NN
cord-103536-etin5i7y	116	2	experiments	experiment	NNS
cord-103536-etin5i7y	116	3	suggest	suggest	VBP
cord-103536-etin5i7y	116	4	that	that	IN
cord-103536-etin5i7y	116	5	the	the	DT
cord-103536-etin5i7y	116	6	C	C	NNP
cord-103536-etin5i7y	116	7	-	-	HYPH
cord-103536-etin5i7y	116	8	terminal	terminal	NN
cord-103536-etin5i7y	116	9	domain	domain	NN
cord-103536-etin5i7y	116	10	is	be	VBZ
cord-103536-etin5i7y	116	11	attached	attach	VBN
cord-103536-etin5i7y	116	12	through	through	IN
cord-103536-etin5i7y	116	13	a	a	DT
cord-103536-etin5i7y	116	14	flexible	flexible	JJ
cord-103536-etin5i7y	116	15	linker	linker	NN
cord-103536-etin5i7y	116	16	.	.	.
cord-103536-etin5i7y	117	1	Established	establish	VBN
cord-103536-etin5i7y	117	2	functions	function	NNS
cord-103536-etin5i7y	117	3	of	of	IN
cord-103536-etin5i7y	117	4	M1	M1	NNP
cord-103536-etin5i7y	117	5	are	be	VBP
cord-103536-etin5i7y	117	6	membrane	membrane	NNP
cord-103536-etin5i7y	117	7	association	association	NN
cord-103536-etin5i7y	117	8	and	and	CC
cord-103536-etin5i7y	117	9	polymerisation	polymerisation	NN
cord-103536-etin5i7y	117	10	of	of	IN
cord-103536-etin5i7y	117	11	the	the	DT
cord-103536-etin5i7y	117	12	Nterminal	Nterminal	NNP
cord-103536-etin5i7y	117	13	domain	domain	NN
cord-103536-etin5i7y	117	14	and	and	CC
cord-103536-etin5i7y	117	15	RNP	RNP	NNP
cord-103536-etin5i7y	117	16	binding	bind	VBG
cord-103536-etin5i7y	117	17	of	of	IN
cord-103536-etin5i7y	117	18	the	the	DT
cord-103536-etin5i7y	117	19	C	c	NN
cord-103536-etin5i7y	117	20	-	-	HYPH
cord-103536-etin5i7y	117	21	terminal	terminal	NN
cord-103536-etin5i7y	117	22	domain	domain	NN
cord-103536-etin5i7y	117	23	[	[	-LRB-
cord-103536-etin5i7y	117	24	46	46	CD
cord-103536-etin5i7y	117	25	]	]	-RRB-
cord-103536-etin5i7y	117	26	.	.	.
cord-103536-etin5i7y	118	1	The	the	DT
cord-103536-etin5i7y	118	2	N	n	CD
cord-103536-etin5i7y	118	3	-	-	HYPH
cord-103536-etin5i7y	118	4	terminal	terminal	NN
cord-103536-etin5i7y	118	5	domain	domain	NN
cord-103536-etin5i7y	118	6	also	also	RB
cord-103536-etin5i7y	118	7	contains	contain	VBZ
cord-103536-etin5i7y	118	8	a	a	DT
cord-103536-etin5i7y	118	9	stretch	stretch	NN
cord-103536-etin5i7y	118	10	of	of	IN
cord-103536-etin5i7y	118	11	basic	basic	JJ
cord-103536-etin5i7y	118	12	residues	residue	NNS
cord-103536-etin5i7y	118	13	,	,	,
cord-103536-etin5i7y	118	14	which	which	WDT
cord-103536-etin5i7y	118	15	have	have	VBP
cord-103536-etin5i7y	118	16	been	be	VBN
cord-103536-etin5i7y	118	17	implicated	implicate	VBN
cord-103536-etin5i7y	118	18	in	in	IN
cord-103536-etin5i7y	118	19	nuclear	nuclear	JJ
cord-103536-etin5i7y	118	20	localisation	localisation	NN
cord-103536-etin5i7y	118	21	of	of	IN
cord-103536-etin5i7y	118	22	M1	M1	NNP
cord-103536-etin5i7y	118	23	and	and	CC
cord-103536-etin5i7y	118	24	export	export	NN
cord-103536-etin5i7y	118	25	processes	process	NNS
cord-103536-etin5i7y	118	26	[	[	-LRB-
cord-103536-etin5i7y	118	27	47	47	CD
cord-103536-etin5i7y	118	28	,	,	,
cord-103536-etin5i7y	118	29	48	48	CD
cord-103536-etin5i7y	118	30	]	]	-RRB-
cord-103536-etin5i7y	118	31	.	.	.
cord-103536-etin5i7y	119	1	Overexpression	Overexpression	NNP
cord-103536-etin5i7y	119	2	of	of	IN
cord-103536-etin5i7y	119	3	M1	M1	NNP
cord-103536-etin5i7y	119	4	in	in	IN
cord-103536-etin5i7y	119	5	eukaryotic	eukaryotic	JJ
cord-103536-etin5i7y	119	6	cells	cell	NNS
cord-103536-etin5i7y	119	7	leads	lead	VBZ
cord-103536-etin5i7y	119	8	to	to	IN
cord-103536-etin5i7y	119	9	the	the	DT
cord-103536-etin5i7y	119	10	formation	formation	NN
cord-103536-etin5i7y	119	11	of	of	IN
cord-103536-etin5i7y	119	12	intracellular	intracellular	JJ
cord-103536-etin5i7y	119	13	tubular	tubular	JJ
cord-103536-etin5i7y	119	14	structures	structure	NNS
cord-103536-etin5i7y	119	15	and	and	CC
cord-103536-etin5i7y	119	16	the	the	DT
cord-103536-etin5i7y	119	17	release	release	NN
cord-103536-etin5i7y	119	18	of	of	IN
cord-103536-etin5i7y	119	19	virus	virus	NN
cord-103536-etin5i7y	119	20	-	-	HYPH
cord-103536-etin5i7y	119	21	like	like	JJ
cord-103536-etin5i7y	119	22	particles	particle	NNS
cord-103536-etin5i7y	119	23	(	(	-LRB-
cord-103536-etin5i7y	119	24	VLPs	vlp	NNS
cord-103536-etin5i7y	119	25	)	)	-RRB-
cord-103536-etin5i7y	119	26	,	,	,
cord-103536-etin5i7y	119	27	indicating	indicate	VBG
cord-103536-etin5i7y	119	28	that	that	IN
cord-103536-etin5i7y	119	29	M1	M1	NNP
cord-103536-etin5i7y	119	30	contains	contain	VBZ
cord-103536-etin5i7y	119	31	all	all	PDT
cord-103536-etin5i7y	119	32	the	the	DT
cord-103536-etin5i7y	119	33	information	information	NN
cord-103536-etin5i7y	119	34	for	for	IN
cord-103536-etin5i7y	119	35	assembly	assembly	NN
cord-103536-etin5i7y	119	36	and	and	CC
cord-103536-etin5i7y	119	37	budding	bud	VBG
cord-103536-etin5i7y	119	38	[	[	-LRB-
cord-103536-etin5i7y	119	39	49	49	CD
cord-103536-etin5i7y	119	40	]	]	-RRB-
cord-103536-etin5i7y	119	41	.	.	.
cord-103536-etin5i7y	120	1	VLP	VLP	NNP
cord-103536-etin5i7y	120	2	formation	formation	NN
cord-103536-etin5i7y	120	3	,	,	,
cord-103536-etin5i7y	120	4	however	however	RB
cord-103536-etin5i7y	120	5	,	,	,
cord-103536-etin5i7y	120	6	is	be	VBZ
cord-103536-etin5i7y	120	7	also	also	RB
cord-103536-etin5i7y	120	8	enhanced	enhance	VBN
cord-103536-etin5i7y	120	9	by	by	IN
cord-103536-etin5i7y	120	10	coexpression	coexpression	NN
cord-103536-etin5i7y	120	11	of	of	IN
cord-103536-etin5i7y	120	12	HA	HA	NNP
cord-103536-etin5i7y	120	13	which	which	WDT
cord-103536-etin5i7y	120	14	might	may	MD
cord-103536-etin5i7y	120	15	augment	augment	VB
cord-103536-etin5i7y	120	16	M1	M1	NNP
cord-103536-etin5i7y	120	17	membrane	membrane	NNP
cord-103536-etin5i7y	120	18	association	association	NNP
cord-103536-etin5i7y	120	19	[	[	-LRB-
cord-103536-etin5i7y	120	20	49	49	CD
cord-103536-etin5i7y	120	21	,	,	,
cord-103536-etin5i7y	120	22	50	50	CD
cord-103536-etin5i7y	120	23	]	]	-RRB-
cord-103536-etin5i7y	120	24	.	.	.
cord-103536-etin5i7y	121	1	Although	although	IN
cord-103536-etin5i7y	121	2	M1	M1	NNP
cord-103536-etin5i7y	121	3	has	have	VBZ
cord-103536-etin5i7y	121	4	a	a	DT
cord-103536-etin5i7y	121	5	high	high	JJ
cord-103536-etin5i7y	121	6	tendency	tendency	NN
cord-103536-etin5i7y	121	7	to	to	TO
cord-103536-etin5i7y	121	8	polymerise	polymerise	VB
cord-103536-etin5i7y	121	9	in	in	IN
cord-103536-etin5i7y	121	10	vitro	vitro	FW
cord-103536-etin5i7y	121	11	,	,	,
cord-103536-etin5i7y	121	12	its	-PRON-	PRP$
cord-103536-etin5i7y	121	13	conformation	conformation	NN
cord-103536-etin5i7y	121	14	upon	upon	IN
cord-103536-etin5i7y	121	15	cytoplasmic	cytoplasmic	JJ
cord-103536-etin5i7y	121	16	expression	expression	NN
cord-103536-etin5i7y	121	17	must	must	MD
cord-103536-etin5i7y	121	18	be	be	VB
cord-103536-etin5i7y	121	19	postulated	postulate	VBN
cord-103536-etin5i7y	121	20	to	to	TO
cord-103536-etin5i7y	121	21	be	be	VB
cord-103536-etin5i7y	121	22	monomeric	monomeric	JJ
cord-103536-etin5i7y	121	23	as	as	IN
cord-103536-etin5i7y	121	24	cytoplasmic	cytoplasmic	JJ
cord-103536-etin5i7y	121	25	and	and	CC
cord-103536-etin5i7y	121	26	nuclear	nuclear	JJ
cord-103536-etin5i7y	121	27	M1	M1	NNP
cord-103536-etin5i7y	121	28	pools	pool	NNS
cord-103536-etin5i7y	121	29	have	have	VBP
cord-103536-etin5i7y	121	30	been	be	VBN
cord-103536-etin5i7y	121	31	reported	report	VBN
cord-103536-etin5i7y	121	32	in	in	IN
cord-103536-etin5i7y	121	33	addition	addition	NN
cord-103536-etin5i7y	121	34	to	to	IN
cord-103536-etin5i7y	121	35	membrane	membrane	NN
cord-103536-etin5i7y	121	36	associated	associate	VBN
cord-103536-etin5i7y	121	37	M1	M1	NNP
cord-103536-etin5i7y	121	38	[	[	-LRB-
cord-103536-etin5i7y	121	39	51	51	CD
cord-103536-etin5i7y	121	40	,	,	,
cord-103536-etin5i7y	121	41	52	52	CD
cord-103536-etin5i7y	121	42	]	]	-RRB-
cord-103536-etin5i7y	121	43	.	.	.
cord-103536-etin5i7y	122	1	The	the	DT
cord-103536-etin5i7y	122	2	activation	activation	NN
cord-103536-etin5i7y	122	3	process	process	NN
cord-103536-etin5i7y	122	4	and	and	CC
cord-103536-etin5i7y	122	5	the	the	DT
cord-103536-etin5i7y	122	6	structural	structural	JJ
cord-103536-etin5i7y	122	7	changes	change	NNS
cord-103536-etin5i7y	122	8	that	that	WDT
cord-103536-etin5i7y	122	9	lead	lead	VBP
cord-103536-etin5i7y	122	10	to	to	IN
cord-103536-etin5i7y	122	11	specific	specific	JJ
cord-103536-etin5i7y	122	12	M1	M1	NNP
cord-103536-etin5i7y	122	13	polymerisation	polymerisation	NN
cord-103536-etin5i7y	122	14	at	at	IN
cord-103536-etin5i7y	122	15	membranes	membrane	NNS
cord-103536-etin5i7y	122	16	in	in	IN
cord-103536-etin5i7y	122	17	vivo	vivo	NN
cord-103536-etin5i7y	122	18	have	have	VBP
cord-103536-etin5i7y	122	19	not	not	RB
cord-103536-etin5i7y	122	20	yet	yet	RB
cord-103536-etin5i7y	122	21	been	be	VBN
cord-103536-etin5i7y	122	22	described	describe	VBN
cord-103536-etin5i7y	122	23	.	.	.
cord-103536-etin5i7y	123	1	M1	M1	NNP
cord-103536-etin5i7y	123	2	also	also	RB
cord-103536-etin5i7y	123	3	exerts	exert	VBZ
cord-103536-etin5i7y	123	4	a	a	DT
cord-103536-etin5i7y	123	5	number	number	NN
cord-103536-etin5i7y	123	6	of	of	IN
cord-103536-etin5i7y	123	7	additional	additional	JJ
cord-103536-etin5i7y	123	8	functions	function	NNS
cord-103536-etin5i7y	123	9	,	,	,
cord-103536-etin5i7y	123	10	such	such	JJ
cord-103536-etin5i7y	123	11	as	as	IN
cord-103536-etin5i7y	123	12	transport	transport	NN
cord-103536-etin5i7y	123	13	of	of	IN
cord-103536-etin5i7y	123	14	RNP	RNP	NNP
cord-103536-etin5i7y	123	15	cores	core	NNS
cord-103536-etin5i7y	123	16	out	out	IN
cord-103536-etin5i7y	123	17	of	of	IN
cord-103536-etin5i7y	123	18	the	the	DT
cord-103536-etin5i7y	123	19	nucleus	nucleus	NN
cord-103536-etin5i7y	123	20	[	[	-LRB-
cord-103536-etin5i7y	123	21	52	52	CD
cord-103536-etin5i7y	123	22	]	]	-RRB-
cord-103536-etin5i7y	123	23	.	.	.
cord-103536-etin5i7y	124	1	No	no	DT
cord-103536-etin5i7y	124	2	functional	functional	JJ
cord-103536-etin5i7y	124	3	late	late	JJ
cord-103536-etin5i7y	124	4	domain	domain	NN
cord-103536-etin5i7y	124	5	sequences	sequence	NNS
cord-103536-etin5i7y	124	6	have	have	VBP
cord-103536-etin5i7y	124	7	yet	yet	RB
cord-103536-etin5i7y	124	8	been	be	VBN
cord-103536-etin5i7y	124	9	described	describe	VBN
cord-103536-etin5i7y	124	10	for	for	IN
cord-103536-etin5i7y	124	11	M1	M1	NNP
cord-103536-etin5i7y	124	12	.	.	.
cord-103536-etin5i7y	125	1	As	as	IN
cord-103536-etin5i7y	125	2	the	the	DT
cord-103536-etin5i7y	125	3	complexity	complexity	NN
cord-103536-etin5i7y	125	4	of	of	IN
cord-103536-etin5i7y	125	5	the	the	DT
cord-103536-etin5i7y	125	6	MVB	MVB	NNP
cord-103536-etin5i7y	125	7	machinery	machinery	NN
cord-103536-etin5i7y	125	8	provides	provide	VBZ
cord-103536-etin5i7y	125	9	multiple	multiple	JJ
cord-103536-etin5i7y	125	10	possible	possible	JJ
cord-103536-etin5i7y	125	11	entry	entry	NN
cord-103536-etin5i7y	125	12	points	point	NNS
cord-103536-etin5i7y	125	13	to	to	TO
cord-103536-etin5i7y	125	14	contribute	contribute	VB
cord-103536-etin5i7y	125	15	to	to	IN
cord-103536-etin5i7y	125	16	its	-PRON-	PRP$
cord-103536-etin5i7y	125	17	activation	activation	NN
cord-103536-etin5i7y	125	18	for	for	IN
cord-103536-etin5i7y	125	19	budding	budding	JJ
cord-103536-etin5i7y	125	20	processes	process	NNS
cord-103536-etin5i7y	125	21	,	,	,
cord-103536-etin5i7y	125	22	it	-PRON-	PRP
cord-103536-etin5i7y	125	23	is	be	VBZ
cord-103536-etin5i7y	125	24	,	,	,
cord-103536-etin5i7y	125	25	however	however	RB
cord-103536-etin5i7y	125	26	,	,	,
cord-103536-etin5i7y	125	27	unlikely	unlikely	JJ
cord-103536-etin5i7y	125	28	that	that	IN
cord-103536-etin5i7y	125	29	influenza	influenza	NN
cord-103536-etin5i7y	125	30	uses	use	VBZ
cord-103536-etin5i7y	125	31	another	another	DT
cord-103536-etin5i7y	125	32	cellular	cellular	JJ
cord-103536-etin5i7y	125	33	machinery	machinery	NN
cord-103536-etin5i7y	125	34	for	for	IN
cord-103536-etin5i7y	125	35	budding	bud	VBG
cord-103536-etin5i7y	125	36	.	.	.
cord-103536-etin5i7y	126	1	The	the	DT
cord-103536-etin5i7y	126	2	crystal	crystal	JJ
cord-103536-etin5i7y	126	3	structure	structure	NN
cord-103536-etin5i7y	126	4	of	of	IN
cord-103536-etin5i7y	126	5	the	the	DT
cord-103536-etin5i7y	126	6	matrix	matrix	NN
cord-103536-etin5i7y	126	7	protein	protein	NN
cord-103536-etin5i7y	126	8	from	from	IN
cord-103536-etin5i7y	126	9	HIV-1	HIV-1	NNP
cord-103536-etin5i7y	126	10	and	and	CC
cord-103536-etin5i7y	126	11	SIV	SIV	NNP
cord-103536-etin5i7y	126	12	folds	fold	VBZ
cord-103536-etin5i7y	126	13	into	into	IN
cord-103536-etin5i7y	126	14	an	an	DT
cord-103536-etin5i7y	126	15	arrangement	arrangement	NN
cord-103536-etin5i7y	126	16	of	of	IN
cord-103536-etin5i7y	126	17	five	five	CD
cord-103536-etin5i7y	126	18	a	a	DT
cord-103536-etin5i7y	126	19	-	-	:
cord-103536-etin5i7y	126	20	helices	helix	NNS
cord-103536-etin5i7y	126	21	and	and	CC
cord-103536-etin5i7y	126	22	a	a	DT
cord-103536-etin5i7y	126	23	three	three	CD
cord-103536-etin5i7y	126	24	-	-	HYPH
cord-103536-etin5i7y	126	25	stranded	strand	VBN
cord-103536-etin5i7y	126	26	mixed	mixed	JJ
cord-103536-etin5i7y	126	27	b	b	NN
cord-103536-etin5i7y	126	28	-	-	HYPH
cord-103536-etin5i7y	126	29	sheet	sheet	NN
cord-103536-etin5i7y	126	30	,	,	,
cord-103536-etin5i7y	126	31	a	a	DT
cord-103536-etin5i7y	126	32	fold	fold	NN
cord-103536-etin5i7y	126	33	,	,	,
cord-103536-etin5i7y	126	34	which	which	WDT
cord-103536-etin5i7y	126	35	is	be	VBZ
cord-103536-etin5i7y	126	36	unique	unique	JJ
cord-103536-etin5i7y	126	37	to	to	IN
cord-103536-etin5i7y	126	38	retroviral	retroviral	JJ
cord-103536-etin5i7y	126	39	matrix	matrix	NN
cord-103536-etin5i7y	126	40	proteins	protein	NNS
cord-103536-etin5i7y	126	41	[	[	-LRB-
cord-103536-etin5i7y	126	42	53	53	CD
cord-103536-etin5i7y	126	43	,	,	,
cord-103536-etin5i7y	126	44	54	54	CD
cord-103536-etin5i7y	126	45	]	]	-RRB-
cord-103536-etin5i7y	126	46	.	.	.
cord-103536-etin5i7y	127	1	Helices	helix	NNS
cord-103536-etin5i7y	127	2	1	1	CD
cord-103536-etin5i7y	127	3	-	-	SYM
cord-103536-etin5i7y	127	4	3	3	CD
cord-103536-etin5i7y	127	5	pack	pack	NN
cord-103536-etin5i7y	127	6	about	about	IN
cord-103536-etin5i7y	127	7	a	a	DT
cord-103536-etin5i7y	127	8	central	central	JJ
cord-103536-etin5i7y	127	9	helix	helix	NN
cord-103536-etin5i7y	127	10	(	(	-LRB-
cord-103536-etin5i7y	127	11	4	4	LS
cord-103536-etin5i7y	127	12	)	)	-RRB-
cord-103536-etin5i7y	127	13	forming	form	VBG
cord-103536-etin5i7y	127	14	a	a	DT
cord-103536-etin5i7y	127	15	compact	compact	JJ
cord-103536-etin5i7y	127	16	globular	globular	JJ
cord-103536-etin5i7y	127	17	domain	domain	NN
cord-103536-etin5i7y	127	18	that	that	WDT
cord-103536-etin5i7y	127	19	is	be	VBZ
cord-103536-etin5i7y	127	20	capped	cap	VBN
cord-103536-etin5i7y	127	21	by	by	IN
cord-103536-etin5i7y	127	22	the	the	DT
cord-103536-etin5i7y	127	23	b	b	NN
cord-103536-etin5i7y	127	24	-	-	HYPH
cord-103536-etin5i7y	127	25	sheet	sheet	NN
cord-103536-etin5i7y	127	26	,	,	,
cord-103536-etin5i7y	127	27	while	while	IN
cord-103536-etin5i7y	127	28	helix	helix	NN
cord-103536-etin5i7y	127	29	5	5	CD
cord-103536-etin5i7y	127	30	extends	extend	VBZ
cord-103536-etin5i7y	127	31	away	away	RB
cord-103536-etin5i7y	127	32	from	from	IN
cord-103536-etin5i7y	127	33	the	the	DT
cord-103536-etin5i7y	127	34	core	core	NN
cord-103536-etin5i7y	127	35	(	(	-LRB-
cord-103536-etin5i7y	127	36	Fig	Fig	NNP
cord-103536-etin5i7y	127	37	.	.	.
cord-103536-etin5i7y	127	38	2(c	2(c	CD
cord-103536-etin5i7y	127	39	)	)	-RRB-
cord-103536-etin5i7y	127	40	)	)	-RRB-
cord-103536-etin5i7y	127	41	.	.	.
cord-103536-etin5i7y	128	1	HIV-1	HIV-1	NNP
cord-103536-etin5i7y	128	2	MA	MA	NNP
cord-103536-etin5i7y	128	3	can	can	MD
cord-103536-etin5i7y	128	4	form	form	VB
cord-103536-etin5i7y	128	5	a	a	DT
cord-103536-etin5i7y	128	6	trimer	trimer	NN
cord-103536-etin5i7y	128	7	in	in	IN
cord-103536-etin5i7y	128	8	solution	solution	NN
cord-103536-etin5i7y	128	9	and	and	CC
cord-103536-etin5i7y	128	10	can	can	MD
cord-103536-etin5i7y	128	11	polymerise	polymerise	VB
cord-103536-etin5i7y	128	12	into	into	IN
cord-103536-etin5i7y	128	13	a	a	DT
cord-103536-etin5i7y	128	14	crystalline	crystalline	JJ
cord-103536-etin5i7y	128	15	lattice	lattice	NN
cord-103536-etin5i7y	128	16	.	.	.
cord-103536-etin5i7y	129	1	The	the	DT
cord-103536-etin5i7y	129	2	trimers	trimer	NNS
cord-103536-etin5i7y	129	3	have	have	VBP
cord-103536-etin5i7y	129	4	been	be	VBN
cord-103536-etin5i7y	129	5	suggested	suggest	VBN
cord-103536-etin5i7y	129	6	to	to	TO
cord-103536-etin5i7y	129	7	form	form	VB
cord-103536-etin5i7y	129	8	the	the	DT
cord-103536-etin5i7y	129	9	building	building	NN
cord-103536-etin5i7y	129	10	block	block	NN
cord-103536-etin5i7y	129	11	for	for	IN
cord-103536-etin5i7y	129	12	the	the	DT
cord-103536-etin5i7y	129	13	mature	mature	JJ
cord-103536-etin5i7y	129	14	MA	MA	NNP
cord-103536-etin5i7y	129	15	shell	shell	NN
cord-103536-etin5i7y	129	16	.	.	.
cord-103536-etin5i7y	130	1	There	there	RB
cord-103536-etin5i7y	130	2	,	,	,
cord-103536-etin5i7y	130	3	the	the	DT
cord-103536-etin5i7y	130	4	individual	individual	JJ
cord-103536-etin5i7y	130	5	trimers	trimer	NNS
cord-103536-etin5i7y	130	6	present	present	VBP
cord-103536-etin5i7y	130	7	a	a	DT
cord-103536-etin5i7y	130	8	largely	largely	RB
cord-103536-etin5i7y	130	9	basic	basic	JJ
cord-103536-etin5i7y	130	10	surface	surface	NN
cord-103536-etin5i7y	130	11	on	on	IN
cord-103536-etin5i7y	130	12	one	one	CD
cord-103536-etin5i7y	130	13	side	side	NN
cord-103536-etin5i7y	130	14	that	that	WDT
cord-103536-etin5i7y	130	15	was	be	VBD
cord-103536-etin5i7y	130	16	proposed	propose	VBN
cord-103536-etin5i7y	130	17	to	to	TO
cord-103536-etin5i7y	130	18	interact	interact	VB
cord-103536-etin5i7y	130	19	with	with	IN
cord-103536-etin5i7y	130	20	the	the	DT
cord-103536-etin5i7y	130	21	inner	inner	JJ
cord-103536-etin5i7y	130	22	membrane	membrane	NN
cord-103536-etin5i7y	130	23	of	of	IN
cord-103536-etin5i7y	130	24	the	the	DT
cord-103536-etin5i7y	130	25	virus	virus	NN
cord-103536-etin5i7y	130	26	.	.	.
cord-103536-etin5i7y	131	1	Such	such	PDT
cord-103536-etin5i7y	131	2	an	an	DT
cord-103536-etin5i7y	131	3	arrangement	arrangement	NN
cord-103536-etin5i7y	131	4	would	would	MD
cord-103536-etin5i7y	131	5	pose	pose	VB
cord-103536-etin5i7y	131	6	the	the	DT
cord-103536-etin5i7y	131	7	myristoylated	myristoylated	JJ
cord-103536-etin5i7y	131	8	N	N	NNP
cord-103536-etin5i7y	131	9	-	-	HYPH
cord-103536-etin5i7y	131	10	terminal	terminal	NN
cord-103536-etin5i7y	131	11	residue	residue	NN
cord-103536-etin5i7y	131	12	that	that	WDT
cord-103536-etin5i7y	131	13	is	be	VBZ
cord-103536-etin5i7y	131	14	essential	essential	JJ
cord-103536-etin5i7y	131	15	for	for	IN
cord-103536-etin5i7y	131	16	membrane	membrane	NN
cord-103536-etin5i7y	131	17	targeting	target	VBG
cord-103536-etin5i7y	131	18	close	close	RB
cord-103536-etin5i7y	131	19	to	to	IN
cord-103536-etin5i7y	131	20	the	the	DT
cord-103536-etin5i7y	131	21	membrane	membrane	NN
cord-103536-etin5i7y	131	22	and	and	CC
cord-103536-etin5i7y	131	23	the	the	DT
cord-103536-etin5i7y	131	24	C	C	NNP
cord-103536-etin5i7y	131	25	-	-	HYPH
cord-103536-etin5i7y	131	26	terminal	terminal	NN
cord-103536-etin5i7y	131	27	helix	helix	NN
cord-103536-etin5i7y	131	28	5	5	CD
cord-103536-etin5i7y	131	29	would	would	MD
cord-103536-etin5i7y	131	30	point	point	VB
cord-103536-etin5i7y	131	31	towards	towards	IN
cord-103536-etin5i7y	131	32	the	the	DT
cord-103536-etin5i7y	131	33	interior	interior	NN
cord-103536-etin5i7y	131	34	of	of	IN
cord-103536-etin5i7y	131	35	the	the	DT
cord-103536-etin5i7y	131	36	viral	viral	JJ
cord-103536-etin5i7y	131	37	particle	particle	NN
cord-103536-etin5i7y	131	38	[	[	-LRB-
cord-103536-etin5i7y	131	39	53	53	CD
cord-103536-etin5i7y	131	40	,	,	,
cord-103536-etin5i7y	131	41	54	54	CD
cord-103536-etin5i7y	131	42	]	]	-RRB-
cord-103536-etin5i7y	131	43	.	.	.
cord-103536-etin5i7y	132	1	In	in	IN
cord-103536-etin5i7y	132	2	addition	addition	NN
cord-103536-etin5i7y	132	3	to	to	IN
cord-103536-etin5i7y	132	4	forming	form	VBG
cord-103536-etin5i7y	132	5	a	a	DT
cord-103536-etin5i7y	132	6	protein	protein	NN
cord-103536-etin5i7y	132	7	shell	shell	NN
cord-103536-etin5i7y	132	8	underneath	underneath	IN
cord-103536-etin5i7y	132	9	the	the	DT
cord-103536-etin5i7y	132	10	viral	viral	JJ
cord-103536-etin5i7y	132	11	membrane	membrane	NN
cord-103536-etin5i7y	132	12	,	,	,
cord-103536-etin5i7y	132	13	MA	MA	NNP
cord-103536-etin5i7y	132	14	is	be	VBZ
cord-103536-etin5i7y	132	15	also	also	RB
cord-103536-etin5i7y	132	16	part	part	NN
cord-103536-etin5i7y	132	17	of	of	IN
cord-103536-etin5i7y	132	18	the	the	DT
cord-103536-etin5i7y	132	19	pre	pre	JJ
cord-103536-etin5i7y	132	20	-	-	NN
cord-103536-etin5i7y	132	21	integration	integration	JJ
cord-103536-etin5i7y	132	22	reverse	reverse	NN
cord-103536-etin5i7y	132	23	transcriptase	transcriptase	NN
cord-103536-etin5i7y	132	24	complex	complex	NN
cord-103536-etin5i7y	132	25	that	that	WDT
cord-103536-etin5i7y	132	26	travels	travel	VBZ
cord-103536-etin5i7y	132	27	towards	towards	IN
cord-103536-etin5i7y	132	28	the	the	DT
cord-103536-etin5i7y	132	29	nucleus	nucleus	NN
cord-103536-etin5i7y	132	30	along	along	IN
cord-103536-etin5i7y	132	31	microtubules	microtubule	NNS
cord-103536-etin5i7y	132	32	using	use	VBG
cord-103536-etin5i7y	132	33	the	the	DT
cord-103536-etin5i7y	132	34	kinesin	kinesin	NN
cord-103536-etin5i7y	132	35	KIF-4	KIF-4	NNP
cord-103536-etin5i7y	132	36	upon	upon	IN
cord-103536-etin5i7y	132	37	viral	viral	JJ
cord-103536-etin5i7y	132	38	entry	entry	NN
cord-103536-etin5i7y	132	39	[	[	-LRB-
cord-103536-etin5i7y	132	40	55	55	CD
cord-103536-etin5i7y	132	41	]	]	-RRB-
cord-103536-etin5i7y	132	42	and	and	CC
cord-103536-etin5i7y	132	43	seems	seem	VBZ
cord-103536-etin5i7y	132	44	to	to	TO
cord-103536-etin5i7y	132	45	be	be	VB
cord-103536-etin5i7y	132	46	required	require	VBN
cord-103536-etin5i7y	132	47	for	for	IN
cord-103536-etin5i7y	132	48	nuclear	nuclear	JJ
cord-103536-etin5i7y	132	49	import	import	NN
cord-103536-etin5i7y	132	50	[	[	-LRB-
cord-103536-etin5i7y	132	51	56	56	CD
cord-103536-etin5i7y	132	52	]	]	-RRB-
cord-103536-etin5i7y	132	53	.	.	.
cord-103536-etin5i7y	133	1	Although	although	IN
cord-103536-etin5i7y	133	2	the	the	DT
cord-103536-etin5i7y	133	3	sequences	sequence	NNS
cord-103536-etin5i7y	133	4	of	of	IN
cord-103536-etin5i7y	133	5	retrovirus	retrovirus	NN
cord-103536-etin5i7y	133	6	matrix	matrix	NN
cord-103536-etin5i7y	133	7	proteins	protein	NNS
cord-103536-etin5i7y	133	8	differ	differ	VBP
cord-103536-etin5i7y	133	9	significantly	significantly	RB
cord-103536-etin5i7y	133	10	,	,	,
cord-103536-etin5i7y	133	11	the	the	DT
cord-103536-etin5i7y	133	12	known	know	VBN
cord-103536-etin5i7y	133	13	structures	structure	NNS
cord-103536-etin5i7y	133	14	of	of	IN
cord-103536-etin5i7y	133	15	retroviral	retroviral	NN
cord-103536-etin5i7y	133	16	matrix	matrix	NN
cord-103536-etin5i7y	133	17	proteins	protein	NNS
cord-103536-etin5i7y	133	18	(	(	-LRB-
cord-103536-etin5i7y	133	19	SIV	SIV	NNP
cord-103536-etin5i7y	133	20	;	;	:
cord-103536-etin5i7y	133	21	bovine	bovine	JJ
cord-103536-etin5i7y	133	22	leukaemia	leukaemia	NN
cord-103536-etin5i7y	133	23	virus	virus	NN
cord-103536-etin5i7y	133	24	,	,	,
cord-103536-etin5i7y	133	25	HTLV	HTLV	NNP
cord-103536-etin5i7y	133	26	-	-	HYPH
cord-103536-etin5i7y	133	27	II	II	NNP
cord-103536-etin5i7y	133	28	;	;	:
cord-103536-etin5i7y	133	29	Mason	Mason	NNP
cord-103536-etin5i7y	133	30	-	-	HYPH
cord-103536-etin5i7y	133	31	Pfizer	Pfizer	NNP
cord-103536-etin5i7y	133	32	monkey	monkey	NN
cord-103536-etin5i7y	133	33	virus	virus	NN
cord-103536-etin5i7y	133	34	;	;	:
cord-103536-etin5i7y	133	35	equine	equine	JJ
cord-103536-etin5i7y	133	36	infectious	infectious	JJ
cord-103536-etin5i7y	133	37	anemia	anemia	NN
cord-103536-etin5i7y	133	38	virus	virus	NN
cord-103536-etin5i7y	133	39	)	)	-RRB-
cord-103536-etin5i7y	133	40	exhibit	exhibit	VBP
cord-103536-etin5i7y	133	41	the	the	DT
cord-103536-etin5i7y	133	42	same	same	JJ
cord-103536-etin5i7y	133	43	common	common	JJ
cord-103536-etin5i7y	133	44	fold	fold	NN
cord-103536-etin5i7y	133	45	reflecting	reflect	VBG
cord-103536-etin5i7y	133	46	their	-PRON-	PRP$
cord-103536-etin5i7y	133	47	evolutionary	evolutionary	JJ
cord-103536-etin5i7y	133	48	relationship	relationship	NN
cord-103536-etin5i7y	133	49	[	[	-LRB-
cord-103536-etin5i7y	133	50	57	57	CD
cord-103536-etin5i7y	133	51	]	]	-RRB-
cord-103536-etin5i7y	133	52	.	.	.
cord-103536-etin5i7y	134	1	Retroviral	retroviral	JJ
cord-103536-etin5i7y	134	2	Gag	Gag	NNP
cord-103536-etin5i7y	134	3	proteins	protein	NNS
cord-103536-etin5i7y	134	4	contain	contain	VBP
cord-103536-etin5i7y	134	5	either	either	CC
cord-103536-etin5i7y	134	6	one	one	CD
cord-103536-etin5i7y	134	7	or	or	CC
cord-103536-etin5i7y	134	8	two	two	CD
cord-103536-etin5i7y	134	9	late	late	JJ
cord-103536-etin5i7y	134	10	domain	domain	NN
cord-103536-etin5i7y	134	11	sequences	sequence	NNS
cord-103536-etin5i7y	134	12	at	at	IN
cord-103536-etin5i7y	134	13	different	different	JJ
cord-103536-etin5i7y	134	14	locations	location	NNS
cord-103536-etin5i7y	134	15	.	.	.
cord-103536-etin5i7y	135	1	HIV-1	HIV-1	NNP
cord-103536-etin5i7y	135	2	Gag	Gag	NNP
cord-103536-etin5i7y	135	3	has	have	VBZ
cord-103536-etin5i7y	135	4	two	two	CD
cord-103536-etin5i7y	135	5	essential	essential	JJ
cord-103536-etin5i7y	135	6	sequence	sequence	NN
cord-103536-etin5i7y	135	7	motifs	motifs	VBP
cord-103536-etin5i7y	135	8	PTAP	PTAP	NNP
cord-103536-etin5i7y	135	9	and	and	CC
cord-103536-etin5i7y	135	10	LXXLF	LXXLF	NNP
cord-103536-etin5i7y	135	11	within	within	IN
cord-103536-etin5i7y	135	12	the	the	DT
cord-103536-etin5i7y	135	13	C	C	NNP
cord-103536-etin5i7y	135	14	-	-	HYPH
cord-103536-etin5i7y	135	15	terminal	terminal	NN
cord-103536-etin5i7y	135	16	fragment	fragment	NN
cord-103536-etin5i7y	135	17	p6	p6	NN
cord-103536-etin5i7y	135	18	while	while	IN
cord-103536-etin5i7y	135	19	PPPY	PPPY	NNP
cord-103536-etin5i7y	135	20	and	and	CC
cord-103536-etin5i7y	135	21	PTAP	PTAP	NNP
cord-103536-etin5i7y	135	22	motifs	motif	NNS
cord-103536-etin5i7y	135	23	locate	locate	VBP
cord-103536-etin5i7y	135	24	to	to	IN
cord-103536-etin5i7y	135	25	the	the	DT
cord-103536-etin5i7y	135	26	C	c	NN
cord-103536-etin5i7y	135	27	-	-	HYPH
cord-103536-etin5i7y	135	28	terminus	terminus	NN
cord-103536-etin5i7y	135	29	of	of	IN
cord-103536-etin5i7y	135	30	MA	MA	NNP
cord-103536-etin5i7y	135	31	from	from	IN
cord-103536-etin5i7y	135	32	HTLV-	HTLV-	NNP
cord-103536-etin5i7y	136	1	I	-PRON-	PRP
cord-103536-etin5i7y	136	2	[	[	-LRB-
cord-103536-etin5i7y	136	3	58	58	CD
cord-103536-etin5i7y	136	4	]	]	-RRB-
cord-103536-etin5i7y	136	5	.	.	.
cord-103536-etin5i7y	137	1	Sequence	sequence	NN
cord-103536-etin5i7y	137	2	analysis	analysis	NN
cord-103536-etin5i7y	137	3	between	between	IN
cord-103536-etin5i7y	137	4	members	member	NNS
cord-103536-etin5i7y	137	5	of	of	IN
cord-103536-etin5i7y	137	6	Filoviridae	Filoviridae	NNP
cord-103536-etin5i7y	137	7	(	(	-LRB-
cord-103536-etin5i7y	137	8	Ebola	Ebola	NNP
cord-103536-etin5i7y	137	9	and	and	CC
cord-103536-etin5i7y	137	10	Marburg	Marburg	NNP
cord-103536-etin5i7y	137	11	virus	virus	NN
cord-103536-etin5i7y	137	12	VP40	VP40	NNP
cord-103536-etin5i7y	137	13	)	)	-RRB-
cord-103536-etin5i7y	137	14	,	,	,
cord-103536-etin5i7y	137	15	Paramyxoviridae	Paramyxoviridae	NNP
cord-103536-etin5i7y	137	16	(	(	-LRB-
cord-103536-etin5i7y	137	17	subfamily	subfamily	NN
cord-103536-etin5i7y	137	18	Paramyxovirinae	Paramyxovirinae	NNP
cord-103536-etin5i7y	137	19	:	:	:
cord-103536-etin5i7y	137	20	Sendai	Sendai	NNP
cord-103536-etin5i7y	137	21	virus	virus	NN
cord-103536-etin5i7y	137	22	,	,	,
cord-103536-etin5i7y	137	23	SV5	SV5	NNP
cord-103536-etin5i7y	137	24	,	,	,
cord-103536-etin5i7y	137	25	measles	measles	NN
cord-103536-etin5i7y	137	26	virus	virus	NN
cord-103536-etin5i7y	137	27	;	;	:
cord-103536-etin5i7y	137	28	and	and	CC
cord-103536-etin5i7y	137	29	subfamily	subfamily	RB
cord-103536-etin5i7y	137	30	pneumovirinae	pneumovirinae	JJ
cord-103536-etin5i7y	137	31	,	,	,
cord-103536-etin5i7y	137	32	human	human	JJ
cord-103536-etin5i7y	137	33	respiratory	respiratory	JJ
cord-103536-etin5i7y	137	34	syncytial	syncytial	JJ
cord-103536-etin5i7y	137	35	virus	virus	NN
cord-103536-etin5i7y	137	36	)	)	-RRB-
cord-103536-etin5i7y	137	37	,	,	,
cord-103536-etin5i7y	137	38	Rhabdoviridae	Rhabdoviridae	NNP
cord-103536-etin5i7y	137	39	(	(	-LRB-
cord-103536-etin5i7y	137	40	VSV	VSV	NNP
cord-103536-etin5i7y	137	41	;	;	,
cord-103536-etin5i7y	137	42	rabies	rabies	NN
cord-103536-etin5i7y	137	43	virus	virus	NN
cord-103536-etin5i7y	137	44	)	)	-RRB-
cord-103536-etin5i7y	137	45	and	and	CC
cord-103536-etin5i7y	137	46	Bornaviridae	Bornaviridae	NNP
cord-103536-etin5i7y	137	47	(	(	-LRB-
cord-103536-etin5i7y	137	48	Borna	Borna	NNP
cord-103536-etin5i7y	137	49	disease	disease	NN
cord-103536-etin5i7y	137	50	virus	virus	NN
cord-103536-etin5i7y	137	51	)	)	-RRB-
cord-103536-etin5i7y	137	52	reveals	reveal	VBZ
cord-103536-etin5i7y	137	53	no	no	DT
cord-103536-etin5i7y	137	54	significant	significant	JJ
cord-103536-etin5i7y	137	55	sequence	sequence	NN
cord-103536-etin5i7y	137	56	identity	identity	NN
cord-103536-etin5i7y	137	57	(	(	-LRB-
cord-103536-etin5i7y	137	58	ranging	range	VBG
cord-103536-etin5i7y	137	59	from	from	IN
cord-103536-etin5i7y	137	60	2	2	CD
cord-103536-etin5i7y	137	61	%	%	NN
cord-103536-etin5i7y	137	62	to	to	TO
cord-103536-etin5i7y	137	63	7	7	CD
cord-103536-etin5i7y	137	64	%	%	NN
cord-103536-etin5i7y	137	65	)	)	-RRB-
cord-103536-etin5i7y	137	66	.	.	.
cord-103536-etin5i7y	138	1	The	the	DT
cord-103536-etin5i7y	138	2	same	same	JJ
cord-103536-etin5i7y	138	3	is	be	VBZ
cord-103536-etin5i7y	138	4	true	true	JJ
cord-103536-etin5i7y	138	5	when	when	WRB
cord-103536-etin5i7y	138	6	comparing	compare	VBG
cord-103536-etin5i7y	138	7	matrix	matrix	NN
cord-103536-etin5i7y	138	8	proteins	protein	NNS
cord-103536-etin5i7y	138	9	from	from	IN
cord-103536-etin5i7y	138	10	the	the	DT
cord-103536-etin5i7y	138	11	Mononegavirales	Mononegavirales	NNPS
cord-103536-etin5i7y	138	12	with	with	IN
cord-103536-etin5i7y	138	13	M1	M1	NNP
cord-103536-etin5i7y	138	14	from	from	IN
cord-103536-etin5i7y	138	15	influenza	influenza	NN
cord-103536-etin5i7y	138	16	virus	virus	NN
cord-103536-etin5i7y	138	17	and	and	CC
cord-103536-etin5i7y	138	18	MA	MA	NNP
cord-103536-etin5i7y	138	19	from	from	IN
cord-103536-etin5i7y	138	20	retroviruses	retrovirus	NNS
cord-103536-etin5i7y	138	21	,	,	,
cord-103536-etin5i7y	138	22	which	which	WDT
cord-103536-etin5i7y	138	23	also	also	RB
cord-103536-etin5i7y	138	24	underlines	underline	VBZ
cord-103536-etin5i7y	138	25	their	-PRON-	PRP$
cord-103536-etin5i7y	138	26	observed	observed	JJ
cord-103536-etin5i7y	138	27	structural	structural	JJ
cord-103536-etin5i7y	138	28	diversity	diversity	NN
cord-103536-etin5i7y	138	29	.	.	.
cord-103536-etin5i7y	139	1	In	in	IN
cord-103536-etin5i7y	139	2	summary	summary	NN
cord-103536-etin5i7y	139	3	,	,	,
cord-103536-etin5i7y	139	4	the	the	DT
cord-103536-etin5i7y	139	5	known	know	VBN
cord-103536-etin5i7y	139	6	matrix	matrix	NN
cord-103536-etin5i7y	139	7	protein	protein	NN
cord-103536-etin5i7y	139	8	structures	structure	NNS
cord-103536-etin5i7y	139	9	indicate	indicate	VBP
cord-103536-etin5i7y	139	10	no	no	DT
cord-103536-etin5i7y	139	11	structural	structural	JJ
cord-103536-etin5i7y	139	12	homology	homology	NN
cord-103536-etin5i7y	139	13	between	between	IN
cord-103536-etin5i7y	139	14	non	non	JJ
cord-103536-etin5i7y	139	15	-	-	JJ
cord-103536-etin5i7y	139	16	segmented	segmented	JJ
cord-103536-etin5i7y	139	17	negative	negative	JJ
cord-103536-etin5i7y	139	18	strand	strand	NN
cord-103536-etin5i7y	139	19	RNA	RNA	NNP
cord-103536-etin5i7y	139	20	viruses	virus	NNS
cord-103536-etin5i7y	139	21	such	such	JJ
cord-103536-etin5i7y	139	22	as	as	IN
cord-103536-etin5i7y	139	23	Filoviridae	Filoviridae	NNP
cord-103536-etin5i7y	139	24	(	(	-LRB-
cord-103536-etin5i7y	139	25	Ebola	Ebola	NNP
cord-103536-etin5i7y	139	26	virus	virus	NN
cord-103536-etin5i7y	139	27	)	)	-RRB-
cord-103536-etin5i7y	139	28	and	and	CC
cord-103536-etin5i7y	139	29	Rhabdoviridae	Rhabdoviridae	NNP
cord-103536-etin5i7y	139	30	(	(	-LRB-
cord-103536-etin5i7y	139	31	VSV	VSV	NNP
cord-103536-etin5i7y	139	32	)	)	-RRB-
cord-103536-etin5i7y	139	33	and	and	CC
cord-103536-etin5i7y	139	34	segmented	segmented	JJ
cord-103536-etin5i7y	139	35	negative	negative	JJ
cord-103536-etin5i7y	139	36	strand	strand	NN
cord-103536-etin5i7y	139	37	RNA	RNA	NNP
cord-103536-etin5i7y	139	38	viruses	virus	NNS
cord-103536-etin5i7y	139	39	such	such	JJ
cord-103536-etin5i7y	139	40	as	as	IN
cord-103536-etin5i7y	139	41	Orthomyxoviridae	Orthomyxoviridae	NNP
cord-103536-etin5i7y	139	42	(	(	-LRB-
cord-103536-etin5i7y	139	43	influenza	influenza	NN
cord-103536-etin5i7y	139	44	virus	virus	NN
cord-103536-etin5i7y	139	45	)	)	-RRB-
cord-103536-etin5i7y	139	46	as	as	RB
cord-103536-etin5i7y	139	47	well	well	RB
cord-103536-etin5i7y	139	48	as	as	IN
cord-103536-etin5i7y	139	49	Retroviridae	Retroviridae	NNP
cord-103536-etin5i7y	139	50	(	(	-LRB-
cord-103536-etin5i7y	139	51	HIV	HIV	NNP
cord-103536-etin5i7y	139	52	)	)	-RRB-
cord-103536-etin5i7y	139	53	,	,	,
cord-103536-etin5i7y	139	54	although	although	IN
cord-103536-etin5i7y	139	55	they	-PRON-	PRP
cord-103536-etin5i7y	139	56	share	share	VBP
cord-103536-etin5i7y	139	57	common	common	JJ
cord-103536-etin5i7y	139	58	functions	function	NNS
cord-103536-etin5i7y	139	59	.	.	.
cord-103536-etin5i7y	140	1	A	a	DT
cord-103536-etin5i7y	140	2	minimal	minimal	JJ
cord-103536-etin5i7y	140	3	structural	structural	JJ
cord-103536-etin5i7y	140	4	conservation	conservation	NN
cord-103536-etin5i7y	140	5	is	be	VBZ
cord-103536-etin5i7y	140	6	the	the	DT
cord-103536-etin5i7y	140	7	presence	presence	NN
cord-103536-etin5i7y	140	8	of	of	IN
cord-103536-etin5i7y	140	9	late	late	JJ
cord-103536-etin5i7y	140	10	domain	domain	NN
cord-103536-etin5i7y	140	11	sequences	sequence	NNS
cord-103536-etin5i7y	140	12	that	that	WDT
cord-103536-etin5i7y	140	13	mediate	mediate	VBP
cord-103536-etin5i7y	140	14	interaction	interaction	NN
cord-103536-etin5i7y	140	15	with	with	IN
cord-103536-etin5i7y	140	16	the	the	DT
cord-103536-etin5i7y	140	17	class	class	NN
cord-103536-etin5i7y	140	18	E	e	NN
cord-103536-etin5i7y	140	19	Vps	Vps	NNP
cord-103536-etin5i7y	140	20	machinery	machinery	NN
cord-103536-etin5i7y	140	21	for	for	IN
cord-103536-etin5i7y	140	22	budding	bud	VBG
cord-103536-etin5i7y	140	23	,	,	,
cord-103536-etin5i7y	140	24	although	although	IN
cord-103536-etin5i7y	140	25	this	this	DT
cord-103536-etin5i7y	140	26	still	still	RB
cord-103536-etin5i7y	140	27	has	have	VBZ
cord-103536-etin5i7y	140	28	to	to	TO
cord-103536-etin5i7y	140	29	be	be	VB
cord-103536-etin5i7y	140	30	shown	show	VBN
cord-103536-etin5i7y	140	31	in	in	IN
cord-103536-etin5i7y	140	32	case	case	NN
cord-103536-etin5i7y	140	33	of	of	IN
cord-103536-etin5i7y	140	34	influenza	influenza	NN
cord-103536-etin5i7y	140	35	virus	virus	NN
cord-103536-etin5i7y	140	36	M1	M1	NNP
cord-103536-etin5i7y	140	37	.	.	.
cord-103536-etin5i7y	141	1	In	in	IN
cord-103536-etin5i7y	141	2	addition	addition	NN
cord-103536-etin5i7y	141	3	,	,	,
cord-103536-etin5i7y	141	4	there	there	EX
cord-103536-etin5i7y	141	5	is	be	VBZ
cord-103536-etin5i7y	141	6	no	no	DT
cord-103536-etin5i7y	141	7	striking	strike	VBG
cord-103536-etin5i7y	141	8	common	common	JJ
cord-103536-etin5i7y	141	9	motif	motif	NN
cord-103536-etin5i7y	141	10	evident	evident	JJ
cord-103536-etin5i7y	141	11	for	for	IN
cord-103536-etin5i7y	141	12	membrane	membrane	NN
cord-103536-etin5i7y	141	13	interaction	interaction	NN
cord-103536-etin5i7y	141	14	,	,	,
cord-103536-etin5i7y	141	15	a	a	DT
cord-103536-etin5i7y	141	16	common	common	JJ
cord-103536-etin5i7y	141	17	functional	functional	JJ
cord-103536-etin5i7y	141	18	property	property	NN
cord-103536-etin5i7y	141	19	of	of	IN
cord-103536-etin5i7y	141	20	all	all	DT
cord-103536-etin5i7y	141	21	viral	viral	JJ
cord-103536-etin5i7y	141	22	matrix	matrix	NN
cord-103536-etin5i7y	141	23	proteins	protein	NNS
cord-103536-etin5i7y	141	24	.	.	.
cord-103536-etin5i7y	142	1	This	this	DT
cord-103536-etin5i7y	142	2	is	be	VBZ
cord-103536-etin5i7y	142	3	in	in	IN
cord-103536-etin5i7y	142	4	contrast	contrast	NN
cord-103536-etin5i7y	142	5	to	to	IN
cord-103536-etin5i7y	142	6	the	the	DT
cord-103536-etin5i7y	142	7	functional	functional	JJ
cord-103536-etin5i7y	142	8	and	and	CC
cord-103536-etin5i7y	142	9	structural	structural	JJ
cord-103536-etin5i7y	142	10	conservation	conservation	NN
cord-103536-etin5i7y	142	11	of	of	IN
cord-103536-etin5i7y	142	12	the	the	DT
cord-103536-etin5i7y	142	13	fusion	fusion	NN
cord-103536-etin5i7y	142	14	protein	protein	NN
cord-103536-etin5i7y	142	15	subunit	subunit	NN
cord-103536-etin5i7y	142	16	of	of	IN
cord-103536-etin5i7y	142	17	the	the	DT
cord-103536-etin5i7y	142	18	glycoproteins	glycoprotein	NNS
cord-103536-etin5i7y	142	19	derived	derive	VBN
cord-103536-etin5i7y	142	20	from	from	IN
cord-103536-etin5i7y	142	21	retroviruses	retrovirus	NNS
cord-103536-etin5i7y	142	22	(	(	-LRB-
cord-103536-etin5i7y	142	23	HIV-1	HIV-1	NNP
cord-103536-etin5i7y	142	24	;	;	:
cord-103536-etin5i7y	142	25	HTLV	HTLV	NNP
cord-103536-etin5i7y	142	26	-	-	HYPH
cord-103536-etin5i7y	142	27	I	I	NNP
cord-103536-etin5i7y	142	28	)	)	-RRB-
cord-103536-etin5i7y	142	29	,	,	,
cord-103536-etin5i7y	142	30	filoviruses	filovirus	NNS
cord-103536-etin5i7y	142	31	(	(	-LRB-
cord-103536-etin5i7y	142	32	Ebola	Ebola	NNP
cord-103536-etin5i7y	142	33	)	)	-RRB-
cord-103536-etin5i7y	142	34	,	,	,
cord-103536-etin5i7y	142	35	paramyxoviruses	paramyxoviruses	NNP
cord-103536-etin5i7y	142	36	(	(	-LRB-
cord-103536-etin5i7y	142	37	SV5	SV5	NNP
cord-103536-etin5i7y	142	38	)	)	-RRB-
cord-103536-etin5i7y	142	39	and	and	CC
cord-103536-etin5i7y	142	40	orthomyxoviruses	orthomyxoviruses	NNP
cord-103536-etin5i7y	142	41	(	(	-LRB-
cord-103536-etin5i7y	142	42	influenza	influenza	NN
cord-103536-etin5i7y	142	43	virus	virus	NN
cord-103536-etin5i7y	142	44	)	)	-RRB-
cord-103536-etin5i7y	142	45	which	which	WDT
cord-103536-etin5i7y	142	46	show	show	VBP
cord-103536-etin5i7y	142	47	striking	strike	VBG
cord-103536-etin5i7y	142	48	similarities	similarity	NNS
cord-103536-etin5i7y	142	49	[	[	-LRB-
cord-103536-etin5i7y	142	50	59	59	CD
cord-103536-etin5i7y	142	51	]	]	-RRB-
cord-103536-etin5i7y	142	52	.	.	.
cord-103536-etin5i7y	143	1	They	-PRON-	PRP
cord-103536-etin5i7y	143	2	all	all	DT
cord-103536-etin5i7y	143	3	fold	fold	VBP
cord-103536-etin5i7y	143	4	into	into	IN
cord-103536-etin5i7y	143	5	trimeric	trimeric	JJ
cord-103536-etin5i7y	143	6	rod	rod	NN
cord-103536-etin5i7y	143	7	-	-	HYPH
cord-103536-etin5i7y	143	8	like	like	JJ
cord-103536-etin5i7y	143	9	structures	structure	NNS
cord-103536-etin5i7y	143	10	composed	compose	VBN
cord-103536-etin5i7y	143	11	of	of	IN
cord-103536-etin5i7y	143	12	a	a	DT
cord-103536-etin5i7y	143	13	central	central	JJ
cord-103536-etin5i7y	143	14	triple	triple	RB
cord-103536-etin5i7y	143	15	-	-	HYPH
cord-103536-etin5i7y	143	16	stranded	stranded	JJ
cord-103536-etin5i7y	143	17	coiled	coiled	JJ
cord-103536-etin5i7y	143	18	coil	coil	NN
cord-103536-etin5i7y	143	19	and	and	CC
cord-103536-etin5i7y	143	20	an	an	DT
cord-103536-etin5i7y	143	21	outer	outer	JJ
cord-103536-etin5i7y	143	22	helical	helical	JJ
cord-103536-etin5i7y	143	23	or	or	CC
cord-103536-etin5i7y	143	24	non	non	JJ
cord-103536-etin5i7y	143	25	-	-	JJ
cord-103536-etin5i7y	143	26	helical	helical	JJ
cord-103536-etin5i7y	143	27	layer	layer	NN
cord-103536-etin5i7y	143	28	.	.	.
cord-103536-etin5i7y	144	1	This	this	DT
cord-103536-etin5i7y	144	2	arrangement	arrangement	NN
cord-103536-etin5i7y	144	3	places	place	VBZ
cord-103536-etin5i7y	144	4	the	the	DT
cord-103536-etin5i7y	144	5	fusion	fusion	NN
cord-103536-etin5i7y	144	6	peptide	peptide	NN
cord-103536-etin5i7y	144	7	and	and	CC
cord-103536-etin5i7y	144	8	the	the	DT
cord-103536-etin5i7y	144	9	transmembrane	transmembrane	NN
cord-103536-etin5i7y	144	10	region	region	NN
cord-103536-etin5i7y	144	11	at	at	IN
cord-103536-etin5i7y	144	12	one	one	CD
cord-103536-etin5i7y	144	13	end	end	NN
cord-103536-etin5i7y	144	14	of	of	IN
cord-103536-etin5i7y	144	15	the	the	DT
cord-103536-etin5i7y	144	16	rod	rod	NN
cord-103536-etin5i7y	144	17	,	,	,
cord-103536-etin5i7y	144	18	which	which	WDT
cord-103536-etin5i7y	144	19	facilitates	facilitate	VBZ
cord-103536-etin5i7y	144	20	fusion	fusion	NN
cord-103536-etin5i7y	144	21	of	of	IN
cord-103536-etin5i7y	144	22	viral	viral	JJ
cord-103536-etin5i7y	144	23	and	and	CC
cord-103536-etin5i7y	144	24	cellular	cellular	JJ
cord-103536-etin5i7y	144	25	membranes	membrane	NNS
cord-103536-etin5i7y	144	26	during	during	IN
cord-103536-etin5i7y	144	27	viral	viral	JJ
cord-103536-etin5i7y	144	28	entry	entry	NN
cord-103536-etin5i7y	144	29	[	[	-LRB-
cord-103536-etin5i7y	144	30	60	60	CD
cord-103536-etin5i7y	144	31	]	]	-RRB-
cord-103536-etin5i7y	144	32	.	.	.
cord-103536-etin5i7y	145	1	The	the	DT
cord-103536-etin5i7y	145	2	conserved	conserved	JJ
cord-103536-etin5i7y	145	3	function	function	NN
cord-103536-etin5i7y	145	4	and	and	CC
cord-103536-etin5i7y	145	5	conformation	conformation	NN
cord-103536-etin5i7y	145	6	of	of	IN
cord-103536-etin5i7y	145	7	the	the	DT
cord-103536-etin5i7y	145	8	fusion	fusion	NN
cord-103536-etin5i7y	145	9	proteins	protein	NNS
cord-103536-etin5i7y	145	10	may	may	MD
cord-103536-etin5i7y	145	11	therefore	therefore	RB
cord-103536-etin5i7y	145	12	be	be	VB
cord-103536-etin5i7y	145	13	based	base	VBN
cord-103536-etin5i7y	145	14	on	on	IN
cord-103536-etin5i7y	145	15	a	a	DT
cord-103536-etin5i7y	145	16	common	common	JJ
cord-103536-etin5i7y	145	17	ancestral	ancestral	JJ
cord-103536-etin5i7y	145	18	viral	viral	JJ
cord-103536-etin5i7y	145	19	fusion	fusion	NN
cord-103536-etin5i7y	145	20	protein	protein	NN
cord-103536-etin5i7y	145	21	[	[	-LRB-
cord-103536-etin5i7y	145	22	61	61	CD
cord-103536-etin5i7y	145	23	]	]	-RRB-
cord-103536-etin5i7y	145	24	.	.	.
cord-103536-etin5i7y	146	1	The	the	DT
cord-103536-etin5i7y	146	2	structural	structural	JJ
cord-103536-etin5i7y	146	3	dissimilarity	dissimilarity	NN
cord-103536-etin5i7y	146	4	of	of	IN
cord-103536-etin5i7y	146	5	matrix	matrix	NN
cord-103536-etin5i7y	146	6	proteins	protein	NNS
cord-103536-etin5i7y	146	7	might	may	MD
cord-103536-etin5i7y	146	8	indicate	indicate	VB
cord-103536-etin5i7y	146	9	two	two	CD
cord-103536-etin5i7y	146	10	different	different	JJ
cord-103536-etin5i7y	146	11	scenarios	scenario	NNS
cord-103536-etin5i7y	146	12	:	:	:
cord-103536-etin5i7y	146	13	(	(	-LRB-
cord-103536-etin5i7y	146	14	i	i	NN
cord-103536-etin5i7y	146	15	)	)	-RRB-
cord-103536-etin5i7y	146	16	Matrix	matrix	NN
cord-103536-etin5i7y	146	17	proteins	protein	NNS
cord-103536-etin5i7y	146	18	from	from	IN
cord-103536-etin5i7y	146	19	related	related	JJ
cord-103536-etin5i7y	146	20	viruses	virus	NNS
cord-103536-etin5i7y	146	21	have	have	VBP
cord-103536-etin5i7y	146	22	evolved	evolve	VBN
cord-103536-etin5i7y	146	23	from	from	IN
cord-103536-etin5i7y	146	24	a	a	DT
cord-103536-etin5i7y	146	25	common	common	JJ
cord-103536-etin5i7y	146	26	ancestor	ancestor	NN
cord-103536-etin5i7y	146	27	and	and	CC
cord-103536-etin5i7y	146	28	have	have	VBP
cord-103536-etin5i7y	146	29	changed	change	VBN
cord-103536-etin5i7y	146	30	over	over	IN
cord-103536-etin5i7y	146	31	time	time	NN
cord-103536-etin5i7y	146	32	completely	completely	RB
cord-103536-etin5i7y	146	33	as	as	IN
cord-103536-etin5i7y	146	34	they	-PRON-	PRP
cord-103536-etin5i7y	146	35	acquired	acquire	VBD
cord-103536-etin5i7y	146	36	new	new	JJ
cord-103536-etin5i7y	146	37	functions	function	NNS
cord-103536-etin5i7y	146	38	that	that	WDT
cord-103536-etin5i7y	146	39	helped	help	VBD
cord-103536-etin5i7y	146	40	to	to	TO
cord-103536-etin5i7y	146	41	adapt	adapt	VB
cord-103536-etin5i7y	146	42	to	to	IN
cord-103536-etin5i7y	146	43	the	the	DT
cord-103536-etin5i7y	146	44	hosts	host	NNS
cord-103536-etin5i7y	146	45	.	.	.
cord-103536-etin5i7y	147	1	Such	such	JJ
cord-103536-etin5i7y	147	2	dramatic	dramatic	JJ
cord-103536-etin5i7y	147	3	changes	change	NNS
cord-103536-etin5i7y	147	4	could	could	MD
cord-103536-etin5i7y	147	5	have	have	VB
cord-103536-etin5i7y	147	6	been	be	VBN
cord-103536-etin5i7y	147	7	supported	support	VBN
cord-103536-etin5i7y	147	8	by	by	IN
cord-103536-etin5i7y	147	9	their	-PRON-	PRP$
cord-103536-etin5i7y	147	10	high	high	JJ
cord-103536-etin5i7y	147	11	mutation	mutation	NN
cord-103536-etin5i7y	147	12	rate	rate	NN
cord-103536-etin5i7y	147	13	[	[	-LRB-
cord-103536-etin5i7y	147	14	62	62	CD
cord-103536-etin5i7y	147	15	]	]	-RRB-
cord-103536-etin5i7y	147	16	.	.	.
cord-103536-etin5i7y	148	1	(	(	-LRB-
cord-103536-etin5i7y	148	2	ii	ii	NN
cord-103536-etin5i7y	148	3	)	)	-RRB-
cord-103536-etin5i7y	149	1	Secondly	secondly	RB
cord-103536-etin5i7y	149	2	,	,	,
cord-103536-etin5i7y	149	3	matrix	matrix	NN
cord-103536-etin5i7y	149	4	proteins	protein	NNS
cord-103536-etin5i7y	149	5	have	have	VBP
cord-103536-etin5i7y	149	6	nothing	nothing	NN
cord-103536-etin5i7y	149	7	in	in	IN
cord-103536-etin5i7y	149	8	common	common	JJ
cord-103536-etin5i7y	149	9	with	with	IN
cord-103536-etin5i7y	149	10	each	each	DT
cord-103536-etin5i7y	149	11	other	other	JJ
cord-103536-etin5i7y	149	12	as	as	IN
cord-103536-etin5i7y	149	13	they	-PRON-	PRP
cord-103536-etin5i7y	149	14	have	have	VBP
cord-103536-etin5i7y	149	15	been	be	VBN
cord-103536-etin5i7y	149	16	acquired	acquire	VBN
cord-103536-etin5i7y	149	17	independently	independently	RB
cord-103536-etin5i7y	149	18	during	during	IN
cord-103536-etin5i7y	149	19	evolution	evolution	NN
cord-103536-etin5i7y	149	20	.	.	.
cord-103536-etin5i7y	150	1	Although	although	IN
cord-103536-etin5i7y	150	2	there	there	EX
cord-103536-etin5i7y	150	3	is	be	VBZ
cord-103536-etin5i7y	150	4	no	no	DT
cord-103536-etin5i7y	150	5	doubt	doubt	NN
cord-103536-etin5i7y	150	6	that	that	IN
cord-103536-etin5i7y	150	7	matrix	matrix	NN
cord-103536-etin5i7y	150	8	proteins	protein	NNS
cord-103536-etin5i7y	150	9	are	be	VBP
cord-103536-etin5i7y	150	10	the	the	DT
cord-103536-etin5i7y	150	11	major	major	JJ
cord-103536-etin5i7y	150	12	driving	driving	NN
cord-103536-etin5i7y	150	13	forces	force	NNS
cord-103536-etin5i7y	150	14	for	for	IN
cord-103536-etin5i7y	150	15	assembly	assembly	NN
cord-103536-etin5i7y	150	16	and	and	CC
cord-103536-etin5i7y	150	17	budding	bud	VBG
cord-103536-etin5i7y	150	18	there	there	EX
cord-103536-etin5i7y	150	19	is	be	VBZ
cord-103536-etin5i7y	150	20	some	some	DT
cord-103536-etin5i7y	150	21	evidence	evidence	NN
cord-103536-etin5i7y	150	22	that	that	IN
cord-103536-etin5i7y	150	23	matrix	matrix	NN
cord-103536-etin5i7y	150	24	protein	protein	NN
cord-103536-etin5i7y	150	25	-	-	HYPH
cord-103536-etin5i7y	150	26	free	free	JJ
cord-103536-etin5i7y	150	27	viruses	virus	NNS
cord-103536-etin5i7y	150	28	might	may	MD
cord-103536-etin5i7y	150	29	have	have	VB
cord-103536-etin5i7y	150	30	existed	exist	VBN
cord-103536-etin5i7y	150	31	as	as	IN
cord-103536-etin5i7y	150	32	matrix	matrix	NN
cord-103536-etin5i7y	150	33	-	-	HYPH
cord-103536-etin5i7y	150	34	less	less	JJR
cord-103536-etin5i7y	150	35	measles	measles	NN
cord-103536-etin5i7y	150	36	virus	virus	NN
cord-103536-etin5i7y	150	37	,	,	,
cord-103536-etin5i7y	150	38	VSV	VSV	NNP
cord-103536-etin5i7y	150	39	and	and	CC
cord-103536-etin5i7y	150	40	rabies	rabies	NN
cord-103536-etin5i7y	150	41	virus	virus	NN
cord-103536-etin5i7y	150	42	show	show	VBP
cord-103536-etin5i7y	150	43	infectivity	infectivity	NN
cord-103536-etin5i7y	150	44	,	,	,
cord-103536-etin5i7y	150	45	albeit	albeit	IN
cord-103536-etin5i7y	150	46	severely	severely	RB
cord-103536-etin5i7y	150	47	impaired	impair	VBD
cord-103536-etin5i7y	150	48	[	[	-LRB-
cord-103536-etin5i7y	150	49	63	63	CD
cord-103536-etin5i7y	150	50	]	]	-RRB-
cord-103536-etin5i7y	150	51	[	[	-LRB-
cord-103536-etin5i7y	150	52	64	64	CD
cord-103536-etin5i7y	150	53	]	]	-RRB-
cord-103536-etin5i7y	151	1	[	[	-LRB-
cord-103536-etin5i7y	151	2	65	65	CD
cord-103536-etin5i7y	151	3	]	]	-RRB-
cord-103536-etin5i7y	151	4	.	.	.
cord-103536-etin5i7y	152	1	In	in	IN
cord-103536-etin5i7y	152	2	addition	addition	NN
cord-103536-etin5i7y	152	3	,	,	,
cord-103536-etin5i7y	152	4	other	other	JJ
cord-103536-etin5i7y	152	5	enveloped	envelop	VBN
cord-103536-etin5i7y	152	6	viruses	virus	NNS
cord-103536-etin5i7y	152	7	have	have	VBP
cord-103536-etin5i7y	152	8	solved	solve	VBN
cord-103536-etin5i7y	152	9	their	-PRON-	PRP$
cord-103536-etin5i7y	152	10	envelope	envelope	NN
cord-103536-etin5i7y	152	11	acquirement	acquirement	NN
cord-103536-etin5i7y	152	12	differently	differently	RB
cord-103536-etin5i7y	152	13	,	,	,
cord-103536-etin5i7y	152	14	namely	namely	RB
cord-103536-etin5i7y	152	15	flaviviruses	flavivirus	NNS
cord-103536-etin5i7y	152	16	and	and	CC
cord-103536-etin5i7y	152	17	alphaviruses	alphavirus	NNS
cord-103536-etin5i7y	152	18	use	use	VBP
cord-103536-etin5i7y	152	19	their	-PRON-	PRP$
cord-103536-etin5i7y	152	20	glycoprotein	glycoprotein	NN
cord-103536-etin5i7y	152	21	to	to	TO
cord-103536-etin5i7y	152	22	form	form	VB
cord-103536-etin5i7y	152	23	a	a	DT
cord-103536-etin5i7y	152	24	protein	protein	NN
cord-103536-etin5i7y	152	25	shell	shell	NN
cord-103536-etin5i7y	152	26	on	on	IN
cord-103536-etin5i7y	152	27	the	the	DT
cord-103536-etin5i7y	152	28	outside	outside	NN
cord-103536-etin5i7y	152	29	of	of	IN
cord-103536-etin5i7y	152	30	the	the	DT
cord-103536-etin5i7y	152	31	lipid	lipid	NN
cord-103536-etin5i7y	152	32	bilayer	bilayer	NN
cord-103536-etin5i7y	152	33	envelope	envelope	NN
cord-103536-etin5i7y	152	34	[	[	-LRB-
cord-103536-etin5i7y	152	35	66	66	CD
cord-103536-etin5i7y	152	36	]	]	-RRB-
cord-103536-etin5i7y	152	37	.	.	.
cord-103536-etin5i7y	153	1	A	a	DT
cord-103536-etin5i7y	153	2	third	third	JJ
cord-103536-etin5i7y	153	3	class	class	NN
cord-103536-etin5i7y	153	4	of	of	IN
cord-103536-etin5i7y	153	5	enveloped	envelop	VBN
cord-103536-etin5i7y	153	6	viruses	virus	NNS
cord-103536-etin5i7y	153	7	,	,	,
cord-103536-etin5i7y	153	8	the	the	DT
cord-103536-etin5i7y	153	9	corona	corona	NN
cord-103536-etin5i7y	153	10	virus	virus	NN
cord-103536-etin5i7y	153	11	uses	use	VBZ
cord-103536-etin5i7y	153	12	an	an	DT
cord-103536-etin5i7y	153	13	integral	integral	JJ
cord-103536-etin5i7y	153	14	membrane	membrane	NN
cord-103536-etin5i7y	153	15	protein	protein	NN
cord-103536-etin5i7y	153	16	that	that	WDT
cord-103536-etin5i7y	153	17	might	may	MD
cord-103536-etin5i7y	153	18	function	function	VB
cord-103536-etin5i7y	153	19	as	as	IN
cord-103536-etin5i7y	153	20	a	a	DT
cord-103536-etin5i7y	153	21	matrix	matrix	NN
cord-103536-etin5i7y	153	22	protein	protein	NN
cord-103536-etin5i7y	153	23	[	[	-LRB-
cord-103536-etin5i7y	153	24	67	67	CD
cord-103536-etin5i7y	153	25	]	]	-RRB-
cord-103536-etin5i7y	153	26	.	.	.
cord-103536-etin5i7y	154	1	In	in	IN
cord-103536-etin5i7y	154	2	conclusion	conclusion	NN
cord-103536-etin5i7y	154	3	,	,	,
cord-103536-etin5i7y	154	4	different	different	JJ
cord-103536-etin5i7y	154	5	matrix	matrix	NN
cord-103536-etin5i7y	154	6	protein	protein	NN
cord-103536-etin5i7y	154	7	conformations	conformation	NNS
cord-103536-etin5i7y	154	8	and/or	and/or	CC
cord-103536-etin5i7y	154	9	their	-PRON-	PRP$
cord-103536-etin5i7y	154	10	diverse	diverse	JJ
cord-103536-etin5i7y	154	11	oligomeric	oligomeric	JJ
cord-103536-etin5i7y	154	12	states	state	NNS
cord-103536-etin5i7y	154	13	or	or	CC
cord-103536-etin5i7y	154	14	polymerisation	polymerisation	NN
cord-103536-etin5i7y	154	15	features	feature	NNS
cord-103536-etin5i7y	154	16	are	be	VBP
cord-103536-etin5i7y	154	17	most	most	RBS
cord-103536-etin5i7y	154	18	likely	likely	JJ
cord-103536-etin5i7y	154	19	to	to	TO
cord-103536-etin5i7y	154	20	contribute	contribute	VB
cord-103536-etin5i7y	154	21	to	to	IN
cord-103536-etin5i7y	154	22	the	the	DT
cord-103536-etin5i7y	154	23	morphological	morphological	JJ
cord-103536-etin5i7y	154	24	differences	difference	NNS
cord-103536-etin5i7y	154	25	between	between	IN
cord-103536-etin5i7y	154	26	viral	viral	JJ
cord-103536-etin5i7y	154	27	families	family	NNS
cord-103536-etin5i7y	154	28	.	.	.
cord-103536-etin5i7y	155	1	Virus	virus	NN
cord-103536-etin5i7y	155	2	maturation	maturation	NN
cord-103536-etin5i7y	155	3	by	by	IN
cord-103536-etin5i7y	155	4	budding	bud	VBG
cord-103536-etin5i7y	155	5	Escaping	escape	VBG
cord-103536-etin5i7y	155	6	from	from	IN
cord-103536-etin5i7y	155	7	the	the	DT
cord-103536-etin5i7y	155	8	cell	cell	NN
cord-103536-etin5i7y	155	9	:	:	:
cord-103536-etin5i7y	155	10	assembly	assembly	NN
cord-103536-etin5i7y	155	11	and	and	CC
cord-103536-etin5i7y	155	12	budding	budding	NN
cord-103536-etin5i7y	155	13	of	of	IN
cord-103536-etin5i7y	155	14	negative	negative	JJ
cord-103536-etin5i7y	155	15	-	-	HYPH
cord-103536-etin5i7y	155	16	strand	strand	NN
cord-103536-etin5i7y	155	17	RNA	RNA	NNP
cord-103536-etin5i7y	155	18	viruses	virus	NNS
cord-103536-etin5i7y	155	19	Membrane	Membrane	NNP
cord-103536-etin5i7y	155	20	vesiculation	vesiculation	NN
cord-103536-etin5i7y	155	21	function	function	NN
cord-103536-etin5i7y	155	22	and	and	CC
cord-103536-etin5i7y	155	23	exocytosis	exocytosis	NN
cord-103536-etin5i7y	155	24	of	of	IN
cord-103536-etin5i7y	155	25	wild	wild	JJ
cord-103536-etin5i7y	155	26	-	-	HYPH
cord-103536-etin5i7y	155	27	type	type	NN
cord-103536-etin5i7y	155	28	and	and	CC
cord-103536-etin5i7y	155	29	mutant	mutant	JJ
cord-103536-etin5i7y	155	30	matrix	matrix	NN
cord-103536-etin5i7y	155	31	proteins	protein	NNS
cord-103536-etin5i7y	155	32	of	of	IN
cord-103536-etin5i7y	155	33	vesicular	vesicular	JJ
cord-103536-etin5i7y	155	34	stomatitis	stomatitis	NN
cord-103536-etin5i7y	155	35	virus	virus	NN
cord-103536-etin5i7y	155	36	Vesicular	Vesicular	NNP
cord-103536-etin5i7y	155	37	release	release	NN
cord-103536-etin5i7y	155	38	of	of	IN
cord-103536-etin5i7y	155	39	ebola	ebola	NNP
cord-103536-etin5i7y	155	40	virus	virus	NN
cord-103536-etin5i7y	155	41	matrix	matrix	NN
cord-103536-etin5i7y	155	42	protein	protein	NN
cord-103536-etin5i7y	155	43	VP40	VP40	NNP
cord-103536-etin5i7y	155	44	Ebola	Ebola	NNP
cord-103536-etin5i7y	155	45	virus	virus	NN
cord-103536-etin5i7y	155	46	VP40-induced	vp40-induced	CD
cord-103536-etin5i7y	155	47	particle	particle	NN
cord-103536-etin5i7y	155	48	formation	formation	NN
cord-103536-etin5i7y	155	49	and	and	CC
cord-103536-etin5i7y	155	50	association	association	NN
cord-103536-etin5i7y	155	51	with	with	IN
cord-103536-etin5i7y	155	52	the	the	DT
cord-103536-etin5i7y	155	53	lipid	lipid	NN
cord-103536-etin5i7y	155	54	bilayer	bilayer	NN
cord-103536-etin5i7y	155	55	Intracellular	Intracellular	NNP
cord-103536-etin5i7y	155	56	transport	transport	NN
cord-103536-etin5i7y	155	57	of	of	IN
cord-103536-etin5i7y	155	58	retroviral	retroviral	JJ
cord-103536-etin5i7y	155	59	capsid	capsid	NN
cord-103536-etin5i7y	155	60	components	component	NNS
cord-103536-etin5i7y	156	1	Influenza	influenza	NN
cord-103536-etin5i7y	156	2	viruses	virus	NNS
cord-103536-etin5i7y	156	3	select	select	VBP
cord-103536-etin5i7y	156	4	ordered	order	VBN
cord-103536-etin5i7y	156	5	lipid	lipid	NN
cord-103536-etin5i7y	156	6	domains	domain	NNS
cord-103536-etin5i7y	156	7	during	during	IN
cord-103536-etin5i7y	156	8	budding	bud	VBG
cord-103536-etin5i7y	156	9	from	from	IN
cord-103536-etin5i7y	156	10	the	the	DT
cord-103536-etin5i7y	156	11	plasma	plasma	NN
cord-103536-etin5i7y	156	12	membrane	membrane	NN
cord-103536-etin5i7y	156	13	Effect	effect	NN
cord-103536-etin5i7y	156	14	of	of	IN
cord-103536-etin5i7y	156	15	mutations	mutation	NNS
cord-103536-etin5i7y	156	16	affecting	affect	VBG
cord-103536-etin5i7y	156	17	the	the	DT
cord-103536-etin5i7y	156	18	p6	p6	NN
cord-103536-etin5i7y	156	19	gag	gag	NN
cord-103536-etin5i7y	156	20	protein	protein	NN
cord-103536-etin5i7y	156	21	on	on	IN
cord-103536-etin5i7y	156	22	human	human	JJ
cord-103536-etin5i7y	156	23	immunodeficiency	immunodeficiency	NN
cord-103536-etin5i7y	156	24	virus	virus	NN
cord-103536-etin5i7y	156	25	particle	particle	NN
cord-103536-etin5i7y	156	26	release	release	NN
cord-103536-etin5i7y	156	27	is	be	VBZ
cord-103536-etin5i7y	156	28	required	require	VBN
cord-103536-etin5i7y	156	29	for	for	IN
cord-103536-etin5i7y	156	30	particle	particle	NN
cord-103536-etin5i7y	156	31	production	production	NN
cord-103536-etin5i7y	156	32	from	from	IN
cord-103536-etin5i7y	156	33	full	full	JJ
cord-103536-etin5i7y	156	34	-	-	HYPH
cord-103536-etin5i7y	156	35	length	length	NN
cord-103536-etin5i7y	156	36	human	human	JJ
cord-103536-etin5i7y	156	37	immunodeficiency	immunodeficiency	NN
cord-103536-etin5i7y	156	38	virus	virus	NN
cord-103536-etin5i7y	156	39	type	type	NN
cord-103536-etin5i7y	156	40	1	1	CD
cord-103536-etin5i7y	156	41	molecular	molecular	JJ
cord-103536-etin5i7y	156	42	clones	clone	NNS
cord-103536-etin5i7y	156	43	expressing	express	VBG
cord-103536-etin5i7y	156	44	protease	protease	NN
cord-103536-etin5i7y	156	45	Mechanisms	Mechanisms	NNPS
cord-103536-etin5i7y	156	46	of	of	IN
cord-103536-etin5i7y	156	47	enveloped	envelop	VBN
cord-103536-etin5i7y	156	48	RNA	RNA	NNP
cord-103536-etin5i7y	156	49	virus	virus	NN
cord-103536-etin5i7y	156	50	budding	bud	VBG
cord-103536-etin5i7y	156	51	Receptor	receptor	NN
cord-103536-etin5i7y	156	52	downregulation	downregulation	NN
cord-103536-etin5i7y	156	53	and	and	CC
cord-103536-etin5i7y	156	54	multivesicular	multivesicular	JJ
cord-103536-etin5i7y	156	55	-	-	HYPH
cord-103536-etin5i7y	156	56	body	body	NN
cord-103536-etin5i7y	156	57	sorting	sort	VBG
cord-103536-etin5i7y	156	58	The	the	DT
cord-103536-etin5i7y	156	59	protein	protein	NN
cord-103536-etin5i7y	156	60	network	network	NN
cord-103536-etin5i7y	156	61	of	of	IN
cord-103536-etin5i7y	156	62	HIV	HIV	NNP
cord-103536-etin5i7y	156	63	budding	bud	VBG
cord-103536-etin5i7y	156	64	AIP1	AIP1	NNP
cord-103536-etin5i7y	157	1	/ALIX	/ALIX	NFP
cord-103536-etin5i7y	157	2	is	be	VBZ
cord-103536-etin5i7y	157	3	a	a	DT
cord-103536-etin5i7y	157	4	binding	bind	VBG
cord-103536-etin5i7y	157	5	partner	partner	NN
cord-103536-etin5i7y	157	6	for	for	IN
cord-103536-etin5i7y	157	7	HIV-1	HIV-1	NNP
cord-103536-etin5i7y	157	8	p6	p6	NNP
cord-103536-etin5i7y	157	9	and	and	CC
cord-103536-etin5i7y	157	10	EIAV	EIAV	NNP
cord-103536-etin5i7y	157	11	p9	p9	NN
cord-103536-etin5i7y	157	12	functioning	function	VBG
cord-103536-etin5i7y	157	13	in	in	IN
cord-103536-etin5i7y	157	14	virus	virus	NN
cord-103536-etin5i7y	157	15	budding	bud	VBG
cord-103536-etin5i7y	157	16	Ubiquitin	Ubiquitin	NNP
cord-103536-etin5i7y	158	1	is	be	VBZ
cord-103536-etin5i7y	158	2	part	part	NN
cord-103536-etin5i7y	158	3	of	of	IN
cord-103536-etin5i7y	158	4	the	the	DT
cord-103536-etin5i7y	158	5	retrovirus	retrovirus	NN
cord-103536-etin5i7y	158	6	budding	bud	VBG
cord-103536-etin5i7y	158	7	machinery	machinery	NN
cord-103536-etin5i7y	158	8	A	a	DT
cord-103536-etin5i7y	158	9	role	role	NN
cord-103536-etin5i7y	158	10	for	for	IN
cord-103536-etin5i7y	158	11	ubiquitin	ubiquitin	NN
cord-103536-etin5i7y	158	12	ligase	ligase	NN
cord-103536-etin5i7y	158	13	recruitment	recruitment	NN
cord-103536-etin5i7y	158	14	in	in	IN
cord-103536-etin5i7y	158	15	retrovirus	retrovirus	NN
cord-103536-etin5i7y	158	16	release	release	NN
cord-103536-etin5i7y	159	1	A	a	DT
cord-103536-etin5i7y	159	2	PPxY	ppxy	JJ
cord-103536-etin5i7y	159	3	motif	motif	NN
cord-103536-etin5i7y	159	4	within	within	IN
cord-103536-etin5i7y	159	5	the	the	DT
cord-103536-etin5i7y	159	6	VP40	VP40	NNP
cord-103536-etin5i7y	159	7	protein	protein	NN
cord-103536-etin5i7y	159	8	of	of	IN
cord-103536-etin5i7y	159	9	Ebola	Ebola	NNP
cord-103536-etin5i7y	159	10	virus	virus	NN
cord-103536-etin5i7y	159	11	interacts	interact	VBZ
cord-103536-etin5i7y	159	12	physically	physically	RB
cord-103536-etin5i7y	159	13	and	and	CC
cord-103536-etin5i7y	159	14	functionally	functionally	RB
cord-103536-etin5i7y	159	15	with	with	IN
cord-103536-etin5i7y	159	16	a	a	DT
cord-103536-etin5i7y	159	17	ubiquitin	ubiquitin	JJ
cord-103536-etin5i7y	159	18	ligase	ligase	NN
cord-103536-etin5i7y	159	19	:	:	:
cord-103536-etin5i7y	159	20	implications	implication	NNS
cord-103536-etin5i7y	159	21	for	for	IN
cord-103536-etin5i7y	159	22	filovirus	filovirus	NN
cord-103536-etin5i7y	159	23	budding	bud	VBG
cord-103536-etin5i7y	159	24	Raft	Raft	NNP
cord-103536-etin5i7y	159	25	-	-	HYPH
cord-103536-etin5i7y	159	26	partitioning	partitioning	NN
cord-103536-etin5i7y	159	27	of	of	IN
cord-103536-etin5i7y	159	28	the	the	DT
cord-103536-etin5i7y	159	29	ubiquitin	ubiquitin	NN
cord-103536-etin5i7y	159	30	ligases	ligase	NNS
cord-103536-etin5i7y	159	31	Cbl	Cbl	NNP
cord-103536-etin5i7y	159	32	and	and	CC
cord-103536-etin5i7y	159	33	Nedd4	nedd4	NN
cord-103536-etin5i7y	159	34	upon	upon	IN
cord-103536-etin5i7y	159	35	IgE	ige	NN
cord-103536-etin5i7y	159	36	-	-	HYPH
cord-103536-etin5i7y	159	37	triggered	trigger	VBN
cord-103536-etin5i7y	159	38	cell	cell	NN
cord-103536-etin5i7y	159	39	signaling	signal	VBG
cord-103536-etin5i7y	159	40	Multivesicular	Multivesicular	NNP
cord-103536-etin5i7y	159	41	body	body	NN
cord-103536-etin5i7y	159	42	sorting	sorting	NN
cord-103536-etin5i7y	159	43	:	:	:
cord-103536-etin5i7y	160	1	ubiquitin	ubiquitin	NNP
cord-103536-etin5i7y	160	2	ligase	ligase	NNP
cord-103536-etin5i7y	160	3	Rsp5	Rsp5	NNP
cord-103536-etin5i7y	160	4	is	be	VBZ
cord-103536-etin5i7y	160	5	required	require	VBN
cord-103536-etin5i7y	160	6	for	for	IN
cord-103536-etin5i7y	160	7	the	the	DT
cord-103536-etin5i7y	160	8	modification	modification	NN
cord-103536-etin5i7y	160	9	and	and	CC
cord-103536-etin5i7y	160	10	sorting	sorting	NN
cord-103536-etin5i7y	160	11	of	of	IN
cord-103536-etin5i7y	160	12	carboxypeptidase	carboxypeptidase	NN
cord-103536-etin5i7y	160	13	S	S	NNP
cord-103536-etin5i7y	160	14	Alix	Alix	NNP
cord-103536-etin5i7y	160	15	(	(	-LRB-
cord-103536-etin5i7y	160	16	ALG-2-interacting	alg-2-interacte	VBG
cord-103536-etin5i7y	160	17	protein	protein	NN
cord-103536-etin5i7y	160	18	X	X	NNP
cord-103536-etin5i7y	160	19	)	)	-RRB-
cord-103536-etin5i7y	160	20	,	,	,
cord-103536-etin5i7y	160	21	a	a	DT
cord-103536-etin5i7y	160	22	protein	protein	NN
cord-103536-etin5i7y	160	23	involved	involve	VBN
cord-103536-etin5i7y	160	24	in	in	IN
cord-103536-etin5i7y	160	25	apoptosis	apoptosis	NN
cord-103536-etin5i7y	160	26	,	,	,
cord-103536-etin5i7y	160	27	binds	bind	VBZ
cord-103536-etin5i7y	160	28	to	to	IN
cord-103536-etin5i7y	160	29	endophilins	endophilin	NNS
cord-103536-etin5i7y	160	30	and	and	CC
cord-103536-etin5i7y	160	31	induces	induce	VBZ
cord-103536-etin5i7y	160	32	cytoplasmic	cytoplasmic	JJ
cord-103536-etin5i7y	160	33	vacuolization	vacuolization	NN
cord-103536-etin5i7y	160	34	Endophilins	Endophilins	NNP
cord-103536-etin5i7y	160	35	interact	interact	VBP
cord-103536-etin5i7y	160	36	with	with	IN
cord-103536-etin5i7y	160	37	Moloney	Moloney	NNP
cord-103536-etin5i7y	160	38	murine	murine	JJ
cord-103536-etin5i7y	160	39	leukemia	leukemia	NN
cord-103536-etin5i7y	160	40	virus	virus	NN
cord-103536-etin5i7y	160	41	Gag	gag	NN
cord-103536-etin5i7y	160	42	and	and	CC
cord-103536-etin5i7y	160	43	modulate	modulate	VB
cord-103536-etin5i7y	160	44	virion	virion	NN
cord-103536-etin5i7y	160	45	production	production	NN
cord-103536-etin5i7y	160	46	Crystal	Crystal	NNP
cord-103536-etin5i7y	160	47	structure	structure	NN
cord-103536-etin5i7y	160	48	of	of	IN
cord-103536-etin5i7y	160	49	the	the	DT
cord-103536-etin5i7y	160	50	matrix	matrix	NN
cord-103536-etin5i7y	160	51	protein	protein	NN
cord-103536-etin5i7y	160	52	VP40	VP40	NNP
cord-103536-etin5i7y	160	53	from	from	IN
cord-103536-etin5i7y	160	54	Ebola	Ebola	NNP
cord-103536-etin5i7y	160	55	virus	virus	NN
cord-103536-etin5i7y	161	1	Structural	structural	JJ
cord-103536-etin5i7y	161	2	characterization	characterization	NN
cord-103536-etin5i7y	161	3	and	and	CC
cord-103536-etin5i7y	161	4	membrane	membrane	NN
cord-103536-etin5i7y	161	5	binding	bind	VBG
cord-103536-etin5i7y	161	6	properties	property	NNS
cord-103536-etin5i7y	161	7	of	of	IN
cord-103536-etin5i7y	161	8	the	the	DT
cord-103536-etin5i7y	161	9	matrix	matrix	NN
cord-103536-etin5i7y	161	10	protein	protein	NN
cord-103536-etin5i7y	161	11	VP40	VP40	NNP
cord-103536-etin5i7y	161	12	of	of	IN
cord-103536-etin5i7y	161	13	Ebola	Ebola	NNP
cord-103536-etin5i7y	161	14	virus	virus	NN
cord-103536-etin5i7y	161	15	Membrane	Membrane	NNP
cord-103536-etin5i7y	161	16	association	association	NNP
cord-103536-etin5i7y	161	17	induces	induce	VBZ
cord-103536-etin5i7y	161	18	a	a	DT
cord-103536-etin5i7y	161	19	conformational	conformational	JJ
cord-103536-etin5i7y	161	20	change	change	NN
cord-103536-etin5i7y	161	21	in	in	IN
cord-103536-etin5i7y	161	22	the	the	DT
cord-103536-etin5i7y	161	23	Ebola	Ebola	NNP
cord-103536-etin5i7y	161	24	virus	virus	NN
cord-103536-etin5i7y	161	25	matrix	matrix	NN
cord-103536-etin5i7y	161	26	protein	protein	NN
cord-103536-etin5i7y	161	27	Oligomerization	Oligomerization	NNP
cord-103536-etin5i7y	161	28	and	and	CC
cord-103536-etin5i7y	161	29	polimerization	polimerization	NN
cord-103536-etin5i7y	161	30	of	of	IN
cord-103536-etin5i7y	161	31	the	the	DT
cord-103536-etin5i7y	161	32	filovirus	filovirus	NN
cord-103536-etin5i7y	161	33	matrix	matrix	NN
cord-103536-etin5i7y	161	34	protein	protein	NN
cord-103536-etin5i7y	162	1	VP40	VP40	NNP
cord-103536-etin5i7y	163	1	The	the	DT
cord-103536-etin5i7y	163	2	matrix	matrix	NN
cord-103536-etin5i7y	163	3	protein	protein	NN
cord-103536-etin5i7y	163	4	VP40	VP40	NNP
cord-103536-etin5i7y	163	5	from	from	IN
cord-103536-etin5i7y	163	6	Ebola	Ebola	NNP
cord-103536-etin5i7y	163	7	virus	virus	NN
cord-103536-etin5i7y	163	8	octamerizes	octamerize	VBZ
cord-103536-etin5i7y	163	9	into	into	IN
cord-103536-etin5i7y	163	10	porelike	porelike	JJ
cord-103536-etin5i7y	163	11	structures	structure	NNS
cord-103536-etin5i7y	163	12	with	with	IN
cord-103536-etin5i7y	163	13	specific	specific	JJ
cord-103536-etin5i7y	163	14	RNA	RNA	NNP
cord-103536-etin5i7y	163	15	binding	binding	NN
cord-103536-etin5i7y	163	16	properties	property	NNS
cord-103536-etin5i7y	164	1	In	in	IN
cord-103536-etin5i7y	164	2	vivo	vivo	NN
cord-103536-etin5i7y	164	3	oligomerization	oligomerization	NN
cord-103536-etin5i7y	164	4	and	and	CC
cord-103536-etin5i7y	164	5	raft	raft	NN
cord-103536-etin5i7y	164	6	localization	localization	NN
cord-103536-etin5i7y	164	7	of	of	IN
cord-103536-etin5i7y	164	8	Ebola	Ebola	NNP
cord-103536-etin5i7y	164	9	virus	virus	NN
cord-103536-etin5i7y	164	10	protein	protein	NN
cord-103536-etin5i7y	164	11	VP40	VP40	NNP
cord-103536-etin5i7y	164	12	during	during	IN
cord-103536-etin5i7y	164	13	vesicular	vesicular	JJ
cord-103536-etin5i7y	164	14	budding	bud	VBG
cord-103536-etin5i7y	164	15	Ebola	Ebola	NNP
cord-103536-etin5i7y	164	16	virus	virus	NN
cord-103536-etin5i7y	164	17	matrix	matrix	NN
cord-103536-etin5i7y	164	18	protein	protein	NN
cord-103536-etin5i7y	164	19	VP40	VP40	NNP
cord-103536-etin5i7y	164	20	interaction	interaction	NN
cord-103536-etin5i7y	164	21	with	with	IN
cord-103536-etin5i7y	164	22	human	human	JJ
cord-103536-etin5i7y	164	23	cellular	cellular	JJ
cord-103536-etin5i7y	164	24	factors	factor	NNS
cord-103536-etin5i7y	165	1	Tsg101	Tsg101	NNP
cord-103536-etin5i7y	165	2	and	and	CC
cord-103536-etin5i7y	166	1	Nedd4	Nedd4	NNP
cord-103536-etin5i7y	166	2	Nedd4	Nedd4	NNP
cord-103536-etin5i7y	166	3	regulates	regulate	VBZ
cord-103536-etin5i7y	166	4	egress	egress	NN
cord-103536-etin5i7y	166	5	of	of	IN
cord-103536-etin5i7y	166	6	Ebola	Ebola	NNP
cord-103536-etin5i7y	166	7	virus	virus	NN
cord-103536-etin5i7y	166	8	-	-	HYPH
cord-103536-etin5i7y	166	9	like	like	JJ
cord-103536-etin5i7y	166	10	particles	particle	NNS
cord-103536-etin5i7y	166	11	from	from	IN
cord-103536-etin5i7y	166	12	host	host	NN
cord-103536-etin5i7y	166	13	cells	cell	NNS
cord-103536-etin5i7y	166	14	HIV-1	HIV-1	NNP
cord-103536-etin5i7y	166	15	and	and	CC
cord-103536-etin5i7y	166	16	Ebola	Ebola	NNP
cord-103536-etin5i7y	166	17	virus	virus	NN
cord-103536-etin5i7y	166	18	encode	encode	VBP
cord-103536-etin5i7y	166	19	small	small	JJ
cord-103536-etin5i7y	166	20	peptide	peptide	NN
cord-103536-etin5i7y	166	21	motifs	motif	NNS
cord-103536-etin5i7y	166	22	that	that	WDT
cord-103536-etin5i7y	166	23	recruit	recruit	VBP
cord-103536-etin5i7y	166	24	Tsg101	tsg101	DT
cord-103536-etin5i7y	166	25	to	to	IN
cord-103536-etin5i7y	166	26	sites	site	NNS
cord-103536-etin5i7y	166	27	of	of	IN
cord-103536-etin5i7y	166	28	particle	particle	NN
cord-103536-etin5i7y	166	29	assembly	assembly	NN
cord-103536-etin5i7y	166	30	to	to	TO
cord-103536-etin5i7y	166	31	facilitate	facilitate	VB
cord-103536-etin5i7y	166	32	egress	egress	NN
cord-103536-etin5i7y	166	33	Overlapping	overlapping	JJ
cord-103536-etin5i7y	166	34	motifs	motif	NNS
cord-103536-etin5i7y	166	35	(	(	-LRB-
cord-103536-etin5i7y	166	36	PTAP	PTAP	NNP
cord-103536-etin5i7y	166	37	and	and	CC
cord-103536-etin5i7y	166	38	PPEY	PPEY	NNP
cord-103536-etin5i7y	166	39	)	)	-RRB-
cord-103536-etin5i7y	166	40	within	within	IN
cord-103536-etin5i7y	166	41	the	the	DT
cord-103536-etin5i7y	166	42	Ebola	Ebola	NNP
cord-103536-etin5i7y	166	43	virus	virus	NN
cord-103536-etin5i7y	166	44	VP40	VP40	NNP
cord-103536-etin5i7y	166	45	protein	protein	NN
cord-103536-etin5i7y	166	46	function	function	VBP
cord-103536-etin5i7y	166	47	independently	independently	RB
cord-103536-etin5i7y	166	48	as	as	IN
cord-103536-etin5i7y	166	49	late	late	JJ
cord-103536-etin5i7y	166	50	budding	bud	VBG
cord-103536-etin5i7y	166	51	domains	domain	NNS
cord-103536-etin5i7y	166	52	:	:	:
cord-103536-etin5i7y	166	53	involvement	involvement	NN
cord-103536-etin5i7y	166	54	of	of	IN
cord-103536-etin5i7y	166	55	host	host	NN
cord-103536-etin5i7y	166	56	proteins	protein	NNS
cord-103536-etin5i7y	166	57	TSG101	TSG101	NNP
cord-103536-etin5i7y	166	58	and	and	CC
cord-103536-etin5i7y	166	59	VPS-4	VPS-4	NNP
cord-103536-etin5i7y	166	60	Crystal	Crystal	NNP
cord-103536-etin5i7y	166	61	structure	structure	NN
cord-103536-etin5i7y	166	62	of	of	IN
cord-103536-etin5i7y	166	63	vesicular	vesicular	JJ
cord-103536-etin5i7y	166	64	stomatitis	stomatitis	NN
cord-103536-etin5i7y	166	65	virus	virus	NN
cord-103536-etin5i7y	166	66	matrix	matrix	NN
cord-103536-etin5i7y	166	67	protein	protein	NN
cord-103536-etin5i7y	166	68	Conformational	Conformational	NNP
cord-103536-etin5i7y	166	69	flexibility	flexibility	NN
cord-103536-etin5i7y	166	70	and	and	CC
cord-103536-etin5i7y	166	71	polymerization	polymerization	NN
cord-103536-etin5i7y	166	72	of	of	IN
cord-103536-etin5i7y	166	73	vesicular	vesicular	JJ
cord-103536-etin5i7y	166	74	stomatitis	stomatitis	NN
cord-103536-etin5i7y	166	75	virus	virus	NN
cord-103536-etin5i7y	166	76	matrix	matrix	NN
cord-103536-etin5i7y	166	77	protein	protein	NN
cord-103536-etin5i7y	166	78	Solubility	solubility	NN
cord-103536-etin5i7y	166	79	of	of	IN
cord-103536-etin5i7y	166	80	vesicular	vesicular	JJ
cord-103536-etin5i7y	166	81	stomatitis	stomatitis	NN
cord-103536-etin5i7y	166	82	virus	virus	NN
cord-103536-etin5i7y	166	83	M	M	NNP
cord-103536-etin5i7y	166	84	protein	protein	NN
cord-103536-etin5i7y	166	85	in	in	IN
cord-103536-etin5i7y	166	86	the	the	DT
cord-103536-etin5i7y	166	87	cytosol	cytosol	NN
cord-103536-etin5i7y	166	88	of	of	IN
cord-103536-etin5i7y	166	89	infected	infected	JJ
cord-103536-etin5i7y	166	90	cells	cell	NNS
cord-103536-etin5i7y	166	91	or	or	CC
cord-103536-etin5i7y	166	92	isolated	isolate	VBN
cord-103536-etin5i7y	166	93	from	from	IN
cord-103536-etin5i7y	166	94	virions	virion	NNS
cord-103536-etin5i7y	166	95	Aggregation	Aggregation	NNP
cord-103536-etin5i7y	166	96	of	of	IN
cord-103536-etin5i7y	166	97	VSV	VSV	NNP
cord-103536-etin5i7y	166	98	M	M	NNP
cord-103536-etin5i7y	166	99	protein	protein	NN
cord-103536-etin5i7y	166	100	is	be	VBZ
cord-103536-etin5i7y	166	101	reversible	reversible	JJ
cord-103536-etin5i7y	166	102	and	and	CC
cord-103536-etin5i7y	166	103	mediated	mediate	VBN
cord-103536-etin5i7y	166	104	by	by	IN
cord-103536-etin5i7y	166	105	nucleation	nucleation	NN
cord-103536-etin5i7y	166	106	sites	site	NNS
cord-103536-etin5i7y	166	107	:	:	:
cord-103536-etin5i7y	167	1	implications	implication	NNS
cord-103536-etin5i7y	167	2	for	for	IN
cord-103536-etin5i7y	167	3	viral	viral	JJ
cord-103536-etin5i7y	167	4	assembly	assembly	NNP
cord-103536-etin5i7y	167	5	Membrane	Membrane	NNP
cord-103536-etin5i7y	167	6	association	association	NNP
cord-103536-etin5i7y	167	7	of	of	IN
cord-103536-etin5i7y	167	8	functional	functional	JJ
cord-103536-etin5i7y	167	9	vesicular	vesicular	JJ
cord-103536-etin5i7y	167	10	stomatitis	stomatitis	NN
cord-103536-etin5i7y	167	11	virus	virus	NN
cord-103536-etin5i7y	167	12	matrix	matrix	NN
cord-103536-etin5i7y	167	13	protein	protein	NN
cord-103536-etin5i7y	167	14	in	in	IN
cord-103536-etin5i7y	167	15	vivo	vivo	NNP
cord-103536-etin5i7y	167	16	Role	role	NN
cord-103536-etin5i7y	167	17	of	of	IN
cord-103536-etin5i7y	167	18	matrix	matrix	NN
cord-103536-etin5i7y	167	19	protein	protein	NN
cord-103536-etin5i7y	167	20	in	in	IN
cord-103536-etin5i7y	167	21	cytopathogenesis	cytopathogenesis	NNP
cord-103536-etin5i7y	167	22	of	of	IN
cord-103536-etin5i7y	167	23	vesicular	vesicular	JJ
cord-103536-etin5i7y	167	24	stomatitis	stomatitis	NNP
cord-103536-etin5i7y	167	25	virus	virus	NN
cord-103536-etin5i7y	168	1	The	the	DT
cord-103536-etin5i7y	168	2	matrix	matrix	NN
cord-103536-etin5i7y	168	3	protein	protein	NN
cord-103536-etin5i7y	168	4	of	of	IN
cord-103536-etin5i7y	168	5	vesicular	vesicular	JJ
cord-103536-etin5i7y	168	6	stomatitis	stomatitis	NN
cord-103536-etin5i7y	168	7	virus	virus	NN
cord-103536-etin5i7y	168	8	inhibits	inhibit	VBZ
cord-103536-etin5i7y	168	9	nucleocytoplasmic	nucleocytoplasmic	JJ
cord-103536-etin5i7y	168	10	transport	transport	NN
cord-103536-etin5i7y	168	11	when	when	WRB
cord-103536-etin5i7y	168	12	it	-PRON-	PRP
cord-103536-etin5i7y	168	13	is	be	VBZ
cord-103536-etin5i7y	168	14	in	in	IN
cord-103536-etin5i7y	168	15	the	the	DT
cord-103536-etin5i7y	168	16	nucleus	nucleus	NN
cord-103536-etin5i7y	168	17	and	and	CC
cord-103536-etin5i7y	168	18	associated	associate	VBN
cord-103536-etin5i7y	168	19	with	with	IN
cord-103536-etin5i7y	168	20	nuclear	nuclear	JJ
cord-103536-etin5i7y	168	21	pore	pore	NN
cord-103536-etin5i7y	168	22	complexes	complex	NNS
cord-103536-etin5i7y	168	23	Vesicular	Vesicular	NNP
cord-103536-etin5i7y	168	24	stomatitis	stomatitis	NN
cord-103536-etin5i7y	168	25	virus	virus	NN
cord-103536-etin5i7y	168	26	matrix	matrix	NN
cord-103536-etin5i7y	168	27	protein	protein	NN
cord-103536-etin5i7y	169	1	inhibits	inhibit	VBZ
cord-103536-etin5i7y	169	2	host	host	NN
cord-103536-etin5i7y	169	3	cell	cell	NN
cord-103536-etin5i7y	169	4	gene	gene	NN
cord-103536-etin5i7y	169	5	expression	expression	NN
cord-103536-etin5i7y	169	6	by	by	IN
cord-103536-etin5i7y	169	7	targeting	target	VBG
cord-103536-etin5i7y	169	8	the	the	DT
cord-103536-etin5i7y	169	9	nucleoporin	nucleoporin	NNP
cord-103536-etin5i7y	169	10	Nup98	Nup98	NNP
cord-103536-etin5i7y	169	11	Complex	Complex	NNP
cord-103536-etin5i7y	169	12	nuclear	nuclear	JJ
cord-103536-etin5i7y	169	13	localization	localization	NN
cord-103536-etin5i7y	169	14	signals	signal	NNS
cord-103536-etin5i7y	169	15	in	in	IN
cord-103536-etin5i7y	169	16	the	the	DT
cord-103536-etin5i7y	169	17	matrix	matrix	NN
cord-103536-etin5i7y	169	18	protein	protein	NN
cord-103536-etin5i7y	169	19	of	of	IN
cord-103536-etin5i7y	169	20	vesicular	vesicular	JJ
cord-103536-etin5i7y	169	21	stomatitis	stomatitis	NN
cord-103536-etin5i7y	169	22	virus	virus	NN
cord-103536-etin5i7y	170	1	The	the	DT
cord-103536-etin5i7y	170	2	cell	cell	NN
cord-103536-etin5i7y	170	3	-	-	HYPH
cord-103536-etin5i7y	170	4	rounding	round	VBG
cord-103536-etin5i7y	170	5	activity	activity	NN
cord-103536-etin5i7y	170	6	of	of	IN
cord-103536-etin5i7y	170	7	the	the	DT
cord-103536-etin5i7y	170	8	vesicular	vesicular	JJ
cord-103536-etin5i7y	170	9	stomatitis	stomatitis	NN
cord-103536-etin5i7y	170	10	virus	virus	NN
cord-103536-etin5i7y	170	11	matrix	matrix	NN
cord-103536-etin5i7y	170	12	protein	protein	NN
cord-103536-etin5i7y	170	13	is	be	VBZ
cord-103536-etin5i7y	170	14	due	due	JJ
cord-103536-etin5i7y	170	15	to	to	IN
cord-103536-etin5i7y	170	16	the	the	DT
cord-103536-etin5i7y	170	17	induction	induction	NN
cord-103536-etin5i7y	170	18	of	of	IN
cord-103536-etin5i7y	170	19	cell	cell	NN
cord-103536-etin5i7y	170	20	death	death	NN
cord-103536-etin5i7y	170	21	Role	role	NN
cord-103536-etin5i7y	170	22	of	of	IN
cord-103536-etin5i7y	170	23	the	the	DT
cord-103536-etin5i7y	170	24	vesicular	vesicular	JJ
cord-103536-etin5i7y	170	25	stomatitis	stomatitis	NN
cord-103536-etin5i7y	170	26	virus	virus	NN
cord-103536-etin5i7y	170	27	matrix	matrix	NN
cord-103536-etin5i7y	170	28	protein	protein	NN
cord-103536-etin5i7y	170	29	in	in	IN
cord-103536-etin5i7y	170	30	maintaining	maintain	VBG
cord-103536-etin5i7y	170	31	the	the	DT
cord-103536-etin5i7y	170	32	viral	viral	JJ
cord-103536-etin5i7y	170	33	nucleocapsid	nucleocapsid	NN
cord-103536-etin5i7y	170	34	in	in	IN
cord-103536-etin5i7y	170	35	the	the	DT
cord-103536-etin5i7y	170	36	condensed	condense	VBN
cord-103536-etin5i7y	170	37	form	form	NN
cord-103536-etin5i7y	170	38	found	find	VBN
cord-103536-etin5i7y	170	39	in	in	IN
cord-103536-etin5i7y	170	40	native	native	JJ
cord-103536-etin5i7y	170	41	virions	virion	NNS
cord-103536-etin5i7y	171	1	The	the	DT
cord-103536-etin5i7y	171	2	assembly	assembly	NN
cord-103536-etin5i7y	171	3	of	of	IN
cord-103536-etin5i7y	171	4	Ebola	Ebola	NNP
cord-103536-etin5i7y	171	5	virus	virus	NN
cord-103536-etin5i7y	171	6	nucleocapsid	nucleocapsid	NN
cord-103536-etin5i7y	171	7	requires	require	VBZ
cord-103536-etin5i7y	171	8	virion	virion	NN
cord-103536-etin5i7y	171	9	-	-	HYPH
cord-103536-etin5i7y	171	10	associated	associate	VBN
cord-103536-etin5i7y	171	11	proteins	protein	NNS
cord-103536-etin5i7y	171	12	35	35	CD
cord-103536-etin5i7y	171	13	and	and	CC
cord-103536-etin5i7y	171	14	24	24	CD
cord-103536-etin5i7y	171	15	and	and	CC
cord-103536-etin5i7y	171	16	posttranslational	posttranslational	JJ
cord-103536-etin5i7y	171	17	modification	modification	NN
cord-103536-etin5i7y	171	18	of	of	IN
cord-103536-etin5i7y	171	19	nucleoprotein	nucleoprotein	NNP
cord-103536-etin5i7y	171	20	Rhabdoviruses	Rhabdoviruses	NNPS
cord-103536-etin5i7y	171	21	and	and	CC
cord-103536-etin5i7y	171	22	the	the	DT
cord-103536-etin5i7y	171	23	cellular	cellular	JJ
cord-103536-etin5i7y	171	24	ubiquitin	ubiquitin	NN
cord-103536-etin5i7y	171	25	-	-	HYPH
cord-103536-etin5i7y	171	26	proteasome	proteasome	VBN
cord-103536-etin5i7y	171	27	system	system	NN
cord-103536-etin5i7y	171	28	:	:	:
cord-103536-etin5i7y	171	29	a	a	DT
cord-103536-etin5i7y	171	30	budding	bud	VBG
cord-103536-etin5i7y	171	31	interaction	interaction	NN
cord-103536-etin5i7y	171	32	Structure	structure	NN
cord-103536-etin5i7y	171	33	of	of	IN
cord-103536-etin5i7y	171	34	a	a	DT
cord-103536-etin5i7y	171	35	bifunctional	bifunctional	JJ
cord-103536-etin5i7y	171	36	membrane	membrane	NN
cord-103536-etin5i7y	171	37	-	-	HYPH
cord-103536-etin5i7y	171	38	RNA	rna	NN
cord-103536-etin5i7y	171	39	binding	binding	NN
cord-103536-etin5i7y	171	40	protein	protein	NN
cord-103536-etin5i7y	171	41	,	,	,
cord-103536-etin5i7y	171	42	influenza	influenza	NN
cord-103536-etin5i7y	171	43	virus	virus	NN
cord-103536-etin5i7y	171	44	matrix	matrix	NN
cord-103536-etin5i7y	171	45	protein	protein	NN
cord-103536-etin5i7y	171	46	M1	M1	NNP
cord-103536-etin5i7y	171	47	Combined	Combined	NNP
cord-103536-etin5i7y	171	48	results	result	NNS
cord-103536-etin5i7y	171	49	from	from	IN
cord-103536-etin5i7y	171	50	solution	solution	NN
cord-103536-etin5i7y	171	51	studies	study	NNS
cord-103536-etin5i7y	171	52	on	on	IN
cord-103536-etin5i7y	171	53	intact	intact	JJ
cord-103536-etin5i7y	172	1	Influeenza	Influeenza	NNP
cord-103536-etin5i7y	172	2	virus	virus	NN
cord-103536-etin5i7y	172	3	M1	M1	NNP
cord-103536-etin5i7y	172	4	protein	protein	NN
cord-103536-etin5i7y	172	5	and	and	CC
cord-103536-etin5i7y	172	6	from	from	IN
cord-103536-etin5i7y	172	7	a	a	DT
cord-103536-etin5i7y	172	8	new	new	JJ
cord-103536-etin5i7y	172	9	crystal	crystal	NN
cord-103536-etin5i7y	172	10	form	form	NN
cord-103536-etin5i7y	172	11	of	of	IN
cord-103536-etin5i7y	172	12	its	-PRON-	PRP$
cord-103536-etin5i7y	172	13	N	n	CD
cord-103536-etin5i7y	172	14	-	-	HYPH
cord-103536-etin5i7y	172	15	terminal	terminal	NN
cord-103536-etin5i7y	172	16	domain	domain	NN
cord-103536-etin5i7y	172	17	show	show	VBP
cord-103536-etin5i7y	172	18	that	that	IN
cord-103536-etin5i7y	172	19	M1	M1	NNP
cord-103536-etin5i7y	172	20	is	be	VBZ
cord-103536-etin5i7y	172	21	an	an	DT
cord-103536-etin5i7y	172	22	elongated	elongated	JJ
cord-103536-etin5i7y	172	23	monomer	monomer	NN
cord-103536-etin5i7y	173	1	In	in	IN
cord-103536-etin5i7y	173	2	vitro	vitro	FW
cord-103536-etin5i7y	173	3	dissection	dissection	NN
cord-103536-etin5i7y	173	4	of	of	IN
cord-103536-etin5i7y	173	5	the	the	DT
cord-103536-etin5i7y	173	6	membrane	membrane	NN
cord-103536-etin5i7y	173	7	and	and	CC
cord-103536-etin5i7y	173	8	RNP	RNP	NNP
cord-103536-etin5i7y	173	9	binding	bind	VBG
cord-103536-etin5i7y	173	10	activities	activity	NNS
cord-103536-etin5i7y	173	11	of	of	IN
cord-103536-etin5i7y	173	12	influenza	influenza	NN
cord-103536-etin5i7y	173	13	virus	virus	NN
cord-103536-etin5i7y	173	14	M1	M1	NNP
cord-103536-etin5i7y	173	15	protein	protein	NN
cord-103536-etin5i7y	173	16	Nucleus	Nucleus	NNP
cord-103536-etin5i7y	173	17	-	-	HYPH
cord-103536-etin5i7y	173	18	targeting	target	VBG
cord-103536-etin5i7y	173	19	domain	domain	NN
cord-103536-etin5i7y	173	20	of	of	IN
cord-103536-etin5i7y	173	21	the	the	DT
cord-103536-etin5i7y	173	22	matrix	matrix	NN
cord-103536-etin5i7y	173	23	protein	protein	NN
cord-103536-etin5i7y	173	24	(	(	-LRB-
cord-103536-etin5i7y	173	25	M1	M1	NNP
cord-103536-etin5i7y	173	26	)	)	-RRB-
cord-103536-etin5i7y	173	27	of	of	IN
cord-103536-etin5i7y	173	28	influenza	influenza	NN
cord-103536-etin5i7y	173	29	virus	virus	NN
cord-103536-etin5i7y	173	30	Crystal	Crystal	NNP
cord-103536-etin5i7y	173	31	structure	structure	NN
cord-103536-etin5i7y	173	32	of	of	IN
cord-103536-etin5i7y	173	33	the	the	DT
cord-103536-etin5i7y	173	34	M1	M1	NNP
cord-103536-etin5i7y	173	35	protein	protein	NN
cord-103536-etin5i7y	173	36	-	-	HYPH
cord-103536-etin5i7y	173	37	binding	bind	VBG
cord-103536-etin5i7y	173	38	domain	domain	NN
cord-103536-etin5i7y	173	39	of	of	IN
cord-103536-etin5i7y	173	40	the	the	DT
cord-103536-etin5i7y	173	41	influenza	influenza	NN
cord-103536-etin5i7y	173	42	A	a	DT
cord-103536-etin5i7y	173	43	virus	virus	NN
cord-103536-etin5i7y	173	44	nuclear	nuclear	JJ
cord-103536-etin5i7y	173	45	export	export	NN
cord-103536-etin5i7y	173	46	protein	protein	NN
cord-103536-etin5i7y	173	47	(	(	-LRB-
cord-103536-etin5i7y	173	48	NEP	NEP	NNP
cord-103536-etin5i7y	173	49	/	/	SYM
cord-103536-etin5i7y	173	50	NS2	NS2	NNP
cord-103536-etin5i7y	173	51	)	)	-RRB-
cord-103536-etin5i7y	174	1	Influenza	influenza	NN
cord-103536-etin5i7y	174	2	virus	virus	NN
cord-103536-etin5i7y	174	3	matrix	matrix	NN
cord-103536-etin5i7y	174	4	protein	protein	NN
cord-103536-etin5i7y	174	5	is	be	VBZ
cord-103536-etin5i7y	174	6	the	the	DT
cord-103536-etin5i7y	174	7	major	major	JJ
cord-103536-etin5i7y	174	8	driving	drive	VBG
cord-103536-etin5i7y	174	9	force	force	NN
cord-103536-etin5i7y	174	10	in	in	IN
cord-103536-etin5i7y	174	11	virus	virus	NN
cord-103536-etin5i7y	174	12	budding	bud	VBG
cord-103536-etin5i7y	174	13	Influenza	Influenza	NNP
cord-103536-etin5i7y	174	14	virus	virus	NN
cord-103536-etin5i7y	174	15	hemagglutinin	hemagglutinin	NN
cord-103536-etin5i7y	174	16	and	and	CC
cord-103536-etin5i7y	174	17	neuraminidase	neuraminidase	NN
cord-103536-etin5i7y	174	18	glycoproteins	glycoprotein	NNS
cord-103536-etin5i7y	174	19	stimulate	stimulate	VBP
cord-103536-etin5i7y	174	20	the	the	DT
cord-103536-etin5i7y	174	21	membrane	membrane	NN
cord-103536-etin5i7y	174	22	association	association	NN
cord-103536-etin5i7y	174	23	of	of	IN
cord-103536-etin5i7y	174	24	the	the	DT
cord-103536-etin5i7y	174	25	matrix	matrix	NN
cord-103536-etin5i7y	174	26	protein	protein	NN
cord-103536-etin5i7y	174	27	Characterization	characterization	NN
cord-103536-etin5i7y	174	28	of	of	IN
cord-103536-etin5i7y	174	29	the	the	DT
cord-103536-etin5i7y	174	30	membrane	membrane	NNP
cord-103536-etin5i7y	174	31	association	association	NNP
cord-103536-etin5i7y	174	32	of	of	IN
cord-103536-etin5i7y	174	33	the	the	DT
cord-103536-etin5i7y	174	34	influenza	influenza	NNP
cord-103536-etin5i7y	174	35	virus	virus	NN
cord-103536-etin5i7y	174	36	matrix	matrix	NN
cord-103536-etin5i7y	174	37	protein	protein	NN
cord-103536-etin5i7y	174	38	in	in	IN
cord-103536-etin5i7y	174	39	living	live	VBG
cord-103536-etin5i7y	174	40	cells	cell	NNS
cord-103536-etin5i7y	174	41	Nuclear	nuclear	JJ
cord-103536-etin5i7y	174	42	transport	transport	NN
cord-103536-etin5i7y	174	43	of	of	IN
cord-103536-etin5i7y	174	44	influenza	influenza	NN
cord-103536-etin5i7y	174	45	virus	virus	NN
cord-103536-etin5i7y	174	46	ribonucleoproteins	ribonucleoproteins	NNP
cord-103536-etin5i7y	174	47	:	:	:
cord-103536-etin5i7y	174	48	the	the	DT
cord-103536-etin5i7y	174	49	viral	viral	JJ
cord-103536-etin5i7y	174	50	matrix	matrix	NN
cord-103536-etin5i7y	174	51	protein	protein	NN
cord-103536-etin5i7y	174	52	(	(	-LRB-
cord-103536-etin5i7y	174	53	M1	M1	NNP
cord-103536-etin5i7y	174	54	)	)	-RRB-
cord-103536-etin5i7y	174	55	promotes	promote	VBZ
cord-103536-etin5i7y	174	56	export	export	NN
cord-103536-etin5i7y	174	57	and	and	CC
cord-103536-etin5i7y	174	58	inhibits	inhibit	VBZ
cord-103536-etin5i7y	174	59	import	import	NN
cord-103536-etin5i7y	174	60	Crystal	Crystal	NNP
cord-103536-etin5i7y	174	61	structures	structure	NNS
cord-103536-etin5i7y	174	62	of	of	IN
cord-103536-etin5i7y	174	63	the	the	DT
cord-103536-etin5i7y	174	64	trimeric	trimeric	NNP
cord-103536-etin5i7y	174	65	human	human	JJ
cord-103536-etin5i7y	174	66	immunodeficiency	immunodeficiency	NN
cord-103536-etin5i7y	174	67	virus	virus	NN
cord-103536-etin5i7y	174	68	type	type	NN
cord-103536-etin5i7y	174	69	1	1	CD
cord-103536-etin5i7y	174	70	matrix	matrix	NN
cord-103536-etin5i7y	174	71	protein	protein	NN
cord-103536-etin5i7y	174	72	:	:	:
cord-103536-etin5i7y	174	73	implications	implication	NNS
cord-103536-etin5i7y	174	74	for	for	IN
cord-103536-etin5i7y	174	75	membrane	membrane	NNP
cord-103536-etin5i7y	174	76	association	association	NNP
cord-103536-etin5i7y	174	77	and	and	CC
cord-103536-etin5i7y	174	78	assembly	assembly	NNP
cord-103536-etin5i7y	174	79	Crystal	Crystal	NNP
cord-103536-etin5i7y	174	80	structure	structure	NN
cord-103536-etin5i7y	174	81	of	of	IN
cord-103536-etin5i7y	174	82	SIV	SIV	NNP
cord-103536-etin5i7y	174	83	matrix	matrix	NN
cord-103536-etin5i7y	174	84	antigen	antigen	NN
cord-103536-etin5i7y	174	85	and	and	CC
cord-103536-etin5i7y	174	86	implications	implication	NNS
cord-103536-etin5i7y	174	87	for	for	IN
cord-103536-etin5i7y	174	88	virus	virus	NN
cord-103536-etin5i7y	174	89	assembly	assembly	NN
cord-103536-etin5i7y	174	90	Visualization	Visualization	NNP
cord-103536-etin5i7y	174	91	of	of	IN
cord-103536-etin5i7y	174	92	the	the	DT
cord-103536-etin5i7y	174	93	intracellular	intracellular	JJ
cord-103536-etin5i7y	174	94	behavior	behavior	NN
cord-103536-etin5i7y	174	95	of	of	IN
cord-103536-etin5i7y	174	96	HIV	HIV	NNP
cord-103536-etin5i7y	174	97	in	in	IN
cord-103536-etin5i7y	174	98	living	living	NN
cord-103536-etin5i7y	174	99	cells	cell	NNS
cord-103536-etin5i7y	175	1	Two	two	CD
cord-103536-etin5i7y	175	2	nuclear	nuclear	JJ
cord-103536-etin5i7y	175	3	localization	localization	NN
cord-103536-etin5i7y	175	4	signals	signal	NNS
cord-103536-etin5i7y	175	5	in	in	IN
cord-103536-etin5i7y	175	6	the	the	DT
cord-103536-etin5i7y	175	7	HIV-1	HIV-1	NNP
cord-103536-etin5i7y	175	8	matrix	matrix	NN
cord-103536-etin5i7y	175	9	protein	protein	NN
cord-103536-etin5i7y	175	10	regulate	regulate	VBP
cord-103536-etin5i7y	175	11	nuclear	nuclear	JJ
cord-103536-etin5i7y	175	12	import	import	NN
cord-103536-etin5i7y	175	13	of	of	IN
cord-103536-etin5i7y	175	14	the	the	DT
cord-103536-etin5i7y	175	15	HIV-1	HIV-1	NNP
cord-103536-etin5i7y	175	16	pre	pre	NN
cord-103536-etin5i7y	175	17	-	-	JJ
cord-103536-etin5i7y	175	18	integration	integration	JJ
cord-103536-etin5i7y	175	19	complex	complex	NN
cord-103536-etin5i7y	175	20	Retroviral	Retroviral	NNP
cord-103536-etin5i7y	175	21	matrix	matrix	NN
cord-103536-etin5i7y	175	22	proteins	protein	NNS
cord-103536-etin5i7y	175	23	:	:	:
cord-103536-etin5i7y	175	24	a	a	DT
cord-103536-etin5i7y	175	25	structural	structural	JJ
cord-103536-etin5i7y	175	26	perspective	perspective	NN
cord-103536-etin5i7y	175	27	HIV	HIV	NNP
cord-103536-etin5i7y	175	28	Gag	Gag	NNP
cord-103536-etin5i7y	175	29	mimics	mimic	VBZ
cord-103536-etin5i7y	175	30	the	the	DT
cord-103536-etin5i7y	175	31	Tsg101-recruiting	tsg101-recruiting	NN
cord-103536-etin5i7y	175	32	activity	activity	NN
cord-103536-etin5i7y	175	33	of	of	IN
cord-103536-etin5i7y	175	34	the	the	DT
cord-103536-etin5i7y	175	35	human	human	JJ
cord-103536-etin5i7y	175	36	Hrs	Hrs	NNP
cord-103536-etin5i7y	175	37	protein	protein	NN
cord-103536-etin5i7y	175	38	Receptor	receptor	NN
cord-103536-etin5i7y	175	39	binding	binding	NN
cord-103536-etin5i7y	175	40	and	and	CC
cord-103536-etin5i7y	175	41	membrane	membrane	NN
cord-103536-etin5i7y	175	42	fusion	fusion	NN
cord-103536-etin5i7y	175	43	in	in	IN
cord-103536-etin5i7y	175	44	virus	virus	NN
cord-103536-etin5i7y	175	45	entry	entry	NN
cord-103536-etin5i7y	175	46	:	:	:
cord-103536-etin5i7y	175	47	the	the	DT
cord-103536-etin5i7y	175	48	influenza	influenza	NN
cord-103536-etin5i7y	175	49	hemagglutinin	hemagglutinin	NN
cord-103536-etin5i7y	175	50	Structural	structural	JJ
cord-103536-etin5i7y	175	51	basis	basis	NN
cord-103536-etin5i7y	175	52	for	for	IN
cord-103536-etin5i7y	175	53	membrane	membrane	NN
cord-103536-etin5i7y	175	54	fusion	fusion	NN
cord-103536-etin5i7y	175	55	by	by	IN
cord-103536-etin5i7y	175	56	enveloped	envelop	VBN
cord-103536-etin5i7y	175	57	viruses	virus	NNS
cord-103536-etin5i7y	175	58	Structure	Structure	NNP
cord-103536-etin5i7y	175	59	of	of	IN
cord-103536-etin5i7y	175	60	the	the	DT
cord-103536-etin5i7y	175	61	haemagglutinin	haemagglutinin	JJ
cord-103536-etin5i7y	175	62	-	-	HYPH
cord-103536-etin5i7y	175	63	esterase	esterase	NN
cord-103536-etin5i7y	175	64	-	-	HYPH
cord-103536-etin5i7y	175	65	fusion	fusion	NN
cord-103536-etin5i7y	175	66	glycoprotein	glycoprotein	NN
cord-103536-etin5i7y	175	67	of	of	IN
cord-103536-etin5i7y	175	68	influenza	influenza	NN
cord-103536-etin5i7y	175	69	C	C	NNP
cord-103536-etin5i7y	175	70	virus	virus	NN
cord-103536-etin5i7y	175	71	RNA	RNA	NNP
cord-103536-etin5i7y	175	72	virus	virus	NN
cord-103536-etin5i7y	175	73	mutations	mutation	NNS
cord-103536-etin5i7y	175	74	and	and	CC
cord-103536-etin5i7y	175	75	fitness	fitness	NN
cord-103536-etin5i7y	175	76	for	for	IN
cord-103536-etin5i7y	175	77	survival	survival	NN
cord-103536-etin5i7y	175	78	Complementation	Complementation	NNP
cord-103536-etin5i7y	175	79	of	of	IN
cord-103536-etin5i7y	175	80	M	M	NNP
cord-103536-etin5i7y	175	81	gene	gene	NN
cord-103536-etin5i7y	175	82	mutants	mutant	NNS
cord-103536-etin5i7y	175	83	of	of	IN
cord-103536-etin5i7y	175	84	vesicular	vesicular	JJ
cord-103536-etin5i7y	175	85	stomatitis	stomatitis	NN
cord-103536-etin5i7y	175	86	virus	virus	NN
cord-103536-etin5i7y	175	87	by	by	IN
cord-103536-etin5i7y	175	88	plasmid	plasmid	NN
cord-103536-etin5i7y	175	89	-	-	HYPH
cord-103536-etin5i7y	175	90	derived	derive	VBN
cord-103536-etin5i7y	175	91	M	M	NNP
cord-103536-etin5i7y	175	92	protein	protein	NN
cord-103536-etin5i7y	175	93	converts	convert	VBZ
cord-103536-etin5i7y	175	94	spherical	spherical	JJ
cord-103536-etin5i7y	175	95	extracellular	extracellular	JJ
cord-103536-etin5i7y	175	96	particles	particle	NNS
cord-103536-etin5i7y	175	97	into	into	IN
cord-103536-etin5i7y	175	98	native	native	JJ
cord-103536-etin5i7y	175	99	bullet	bullet	NN
cord-103536-etin5i7y	175	100	shapes	shape	NNS
cord-103536-etin5i7y	176	1	A	a	DT
cord-103536-etin5i7y	176	2	matrix	matrix	NN
cord-103536-etin5i7y	176	3	-	-	HYPH
cord-103536-etin5i7y	176	4	less	less	JJR
cord-103536-etin5i7y	176	5	measles	measle	NNS
cord-103536-etin5i7y	176	6	virus	virus	NN
cord-103536-etin5i7y	176	7	is	be	VBZ
cord-103536-etin5i7y	176	8	infectious	infectious	JJ
cord-103536-etin5i7y	176	9	and	and	CC
cord-103536-etin5i7y	176	10	elicits	elicit	VBZ
cord-103536-etin5i7y	176	11	extensive	extensive	JJ
cord-103536-etin5i7y	176	12	cell	cell	NN
cord-103536-etin5i7y	176	13	fusion	fusion	NN
cord-103536-etin5i7y	176	14	:	:	:
cord-103536-etin5i7y	176	15	consequences	consequence	NNS
cord-103536-etin5i7y	176	16	for	for	IN
cord-103536-etin5i7y	176	17	propagation	propagation	NN
cord-103536-etin5i7y	176	18	in	in	IN
cord-103536-etin5i7y	176	19	the	the	DT
cord-103536-etin5i7y	176	20	brain	brain	NN
cord-103536-etin5i7y	176	21	Matrix	Matrix	NNP
cord-103536-etin5i7y	176	22	protein	protein	NN
cord-103536-etin5i7y	176	23	of	of	IN
cord-103536-etin5i7y	176	24	rabies	rabies	NN
cord-103536-etin5i7y	176	25	virus	virus	NN
cord-103536-etin5i7y	176	26	is	be	VBZ
cord-103536-etin5i7y	176	27	responsible	responsible	JJ
cord-103536-etin5i7y	176	28	for	for	IN
cord-103536-etin5i7y	176	29	the	the	DT
cord-103536-etin5i7y	176	30	assembly	assembly	NN
cord-103536-etin5i7y	176	31	and	and	CC
cord-103536-etin5i7y	176	32	budding	budding	NN
cord-103536-etin5i7y	176	33	of	of	IN
cord-103536-etin5i7y	176	34	bullet	bullet	NN
cord-103536-etin5i7y	176	35	-	-	HYPH
cord-103536-etin5i7y	176	36	shaped	shape	VBN
cord-103536-etin5i7y	176	37	particles	particle	NNS
cord-103536-etin5i7y	176	38	and	and	CC
cord-103536-etin5i7y	176	39	interacts	interact	VBZ
cord-103536-etin5i7y	176	40	with	with	IN
cord-103536-etin5i7y	176	41	the	the	DT
cord-103536-etin5i7y	176	42	transmembrane	transmembrane	NN
cord-103536-etin5i7y	176	43	spike	spike	NN
cord-103536-etin5i7y	176	44	glycoprotein	glycoprotein	NN
cord-103536-etin5i7y	176	45	G	g	NN
cord-103536-etin5i7y	176	46	Enveloped	Enveloped	NNP
cord-103536-etin5i7y	176	47	viruses	virus	NNS
cord-103536-etin5i7y	176	48	SARS	SARS	NNP
cord-103536-etin5i7y	176	49	:	:	:
cord-103536-etin5i7y	176	50	beginning	begin	VBG
cord-103536-etin5i7y	176	51	to	to	TO
cord-103536-etin5i7y	176	52	understand	understand	VB
cord-103536-etin5i7y	176	53	a	a	DT
cord-103536-etin5i7y	176	54	new	new	JJ
cord-103536-etin5i7y	176	55	virus	virus	NN
cord-103536-etin5i7y	176	56	We	-PRON-	PRP
cord-103536-etin5i7y	176	57	gratefully	gratefully	RB
cord-103536-etin5i7y	176	58	acknowledge	acknowledge	VBP
cord-103536-etin5i7y	176	59	critical	critical	JJ
cord-103536-etin5i7y	176	60	comments	comment	NNS
cord-103536-etin5i7y	176	61	on	on	IN
cord-103536-etin5i7y	176	62	the	the	DT
cord-103536-etin5i7y	176	63	manuscript	manuscript	NN
cord-103536-etin5i7y	176	64	by	by	IN
cord-103536-etin5i7y	176	65	Dr.	Dr.	NNP
cord-103536-etin5i7y	176	66	Stephan	Stephan	NNP
cord-103536-etin5i7y	176	67	Becker	Becker	NNP
cord-103536-etin5i7y	176	68	and	and	CC
cord-103536-etin5i7y	176	69	apologize	apologize	VB
cord-103536-etin5i7y	176	70	to	to	IN
cord-103536-etin5i7y	176	71	the	the	DT
cord-103536-etin5i7y	176	72	many	many	JJ
cord-103536-etin5i7y	176	73	colleagues	colleague	NNS
cord-103536-etin5i7y	176	74	whose	whose	WP$
cord-103536-etin5i7y	176	75	work	work	NN
cord-103536-etin5i7y	176	76	we	-PRON-	PRP
cord-103536-etin5i7y	176	77	were	be	VBD
cord-103536-etin5i7y	176	78	unable	unable	JJ
cord-103536-etin5i7y	176	79	to	to	TO
cord-103536-etin5i7y	176	80	cite	cite	VB
cord-103536-etin5i7y	176	81	due	due	IN
cord-103536-etin5i7y	176	82	to	to	IN
cord-103536-etin5i7y	176	83	the	the	DT
cord-103536-etin5i7y	176	84	publishers	publisher	NNS
cord-103536-etin5i7y	176	85	space	space	NN
cord-103536-etin5i7y	176	86	limitations	limitation	NNS
cord-103536-etin5i7y	176	87	.	.	.